产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
beta连环蛋白单克隆抗体(猫-5H10)
目录 :
13-8400
规格 :
100微克
价格 :
美国455.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
猫-5H10
反应物种 :
人类, 小鼠, 大鼠, 犬, 鸡, 牛, 猕猴
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 其他
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 126
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:300; 表 1
Wilhelm F, Böger C, Krüger S, Behrens H, Rocken C. Troy is expressed in human stomach mucosa and a novel putative prognostic marker of intestinal type gastric cancer. Oncotarget. 2017;8:50557-50569 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5b
Wan H, Cai J, Chen F, Zhu J, Zhong J, Zhong H. SOX12: a novel potential target for acute myeloid leukaemia. Br J Haematol. 2017;176:421-430 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3b
Lobato Álvarez J, Roldán M, López Murillo T, González Ramírez R, Bonilla Delgado J, Shoshani L. The Apical Localization of Na+, K+-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the ?2 Subunit. Front Physiol. 2016;7:450 pubmed
  • 免疫细胞化学; 人类; 图 1
Arévalo Romero H, Meza I, Vallejo Flores G, Fuentes Panana E. Helicobacter pylori CagA and IL-1? Promote the Epithelial-to-Mesenchymal Transition in a Nontransformed Epithelial Cell Model. Gastroenterol Res Pract. 2016;2016:4969163 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
De Pauw A, Massion P, Sekkali B, André E, Dubroca C, Kmecova J, et al. Paracrine nitric oxide induces expression of cardiac sarcomeric proteins in adult progenitor cells through soluble guanylyl cyclase/cyclic-guanosine monophosphate and Wnt/?-catenin inhibition. Cardiovasc Res. 2016;112:478-90 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 1
  • 免疫印迹; 大鼠; 1:500; 图 1
Li N, Mruk D, Chen H, Wong C, Lee W, Cheng C. Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43. Sci Rep. 2016;6:29667 pubmed 出版商
  • 免疫组化-石蜡切片; 犬; 1:100; 图 1a
Payan Carreira R, Pires M, Santos C, Holst B, Colaco J, Rodriguez Martinez H. Immunolocalization of E-cadherin and ?-catenin in the cyclic and early pregnant canine endometrium. Theriogenology. 2016;86:1092-1101 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 7
  • 免疫印迹; 小鼠; 图 8
Falcão V, Maschio D, de Fontes C, Oliveira R, Santos Silva J, Almeida A, et al. Reduced insulin secretion function is associated with pancreatic islet redistribution of cell adhesion molecules (CAMS) in diabetic mice after prolonged high-fat diet. Histochem Cell Biol. 2016;146:13-31 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 3
  • 免疫印迹; 大鼠; 1:300; 图 3
Chen H, Mruk D, Lee W, Cheng C. Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats. Endocrinology. 2016;157:2140-59 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Xu X, Zhang Y, Jasper J, Lykken E, Alexander P, Markowitz G, et al. MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer. Oncotarget. 2016;7:20381-94 pubmed 出版商
  • 其他; 人类; 图 st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
  • 免疫印迹; 人类; 1:2000; 图 2a
Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:300
Figueira A, Gomes C, Vilhena H, Miranda S, Carvalheira J, de Matos A, et al. Characterization of α-, β- and p120-Catenin Expression in Feline Mammary Tissues and their Relation with E- and P-Cadherin. Anticancer Res. 2015;35:3361-9 pubmed
  • 免疫细胞化学; 人类; 1:100; 图 1d
Zhu D, Wang Z, Zhao J, Calimeri T, Meng J, Hideshima T, et al. The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells. Nat Med. 2015;21:572-80 pubmed 出版商
  • 免疫组化; 大鼠; 1:500
Tennakoon A, Izawa T, Wijesundera K, Katou Ichikawa C, Tanaka M, Golbar H, et al. Analysis of glial fibrillary acidic protein (GFAP)-expressing ductular cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA). Exp Mol Pathol. 2015;98:476-85 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 6
Whish S, Dziegielewska K, MøllgÃ¥rd K, Noor N, Liddelow S, Habgood M, et al. The inner CSF-brain barrier: developmentally controlled access to the brain via intercellular junctions. Front Neurosci. 2015;9:16 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Chong K, Hsu C, Hung T, Hu H, Huang T, Wang T, et al. Wnt pathway activation and ABCB1 expression account for attenuation of proteasome inhibitor-mediated apoptosis in multidrug-resistant cancer cells. Cancer Biol Ther. 2015;16:149-59 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:1000
Xu X, Kim J, Sun P, Yoo S, Kim H, Jin Y, et al. Immunohistochemical demonstration of alteration of β-catenin during tumor metastasis by different mechanisms according to histology in lung cancer. Exp Ther Med. 2015;9:311-318 pubmed
  • 免疫组化-冰冻切片; 大鼠; 1:100
  • 免疫印迹; 大鼠; 1:300
Tang E, Mok K, Lee W, Cheng C. EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study. Endocrinology. 2015;156:680-93 pubmed 出版商
  • 免疫印迹; 人类
Hung T, Hsu S, Cheng C, Choo K, Tseng C, Chen T, et al. Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway. Oncotarget. 2014;5:12273-90 pubmed
  • 免疫细胞化学; 人类
Hagos Y, Wegner W, Kuehne A, Floerl S, Marada V, Burckhardt G, et al. HNF4α induced chemosensitivity to oxaliplatin and 5-FU mediated by OCT1 and CNT3 in renal cell carcinoma. J Pharm Sci. 2014;103:3326-34 pubmed 出版商
  • 免疫印迹; 人类
Jin G, Liu B, You Z, Bambakidis T, Dekker S, Maxwell J, et al. Development of a novel neuroprotective strategy: combined treatment with hypothermia and valproic acid improves survival in hypoxic hippocampal cells. Surgery. 2014;156:221-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:1000
Li J, Bai X, Zou Y, Hao Y, Xu X. Aberration of the Wnt signaling pathway in pulmonary fatal adenocarcinoma: a case report. Chin J Cancer Res. 2014;26:E13-6 pubmed 出版商
  • 免疫组化-石蜡切片; 犬; 1:150
Rodrigues M, Rema A, Gartner M, Laufer Amorim R. Role of adhesion molecules and proliferation hyperplasic, pre neoplastic and neoplastic lesions in canine prostate. Pak J Biol Sci. 2013;16:1324-9 pubmed
  • 免疫组化; 人类; 1:2000
Kim S, Kim M, Kim M, Kim S, Choi J, Yu E, et al. Pleomorphic solid pseudopapillary neoplasm of the pancreas: degenerative change rather than high-grade malignant potential. Hum Pathol. 2014;45:166-74 pubmed 出版商
  • 免疫组化; 人类; 图 2
Krabbe L, Westerman M, Bagrodia A, Gayed B, Darwish O, Haddad A, et al. Dysregulation of ?-catenin is an independent predictor of oncologic outcomes in patients with clear cell renal cell carcinoma. J Urol. 2014;191:1671-7 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Gu M, Choi J. Epithelial-mesenchymal transition phenotypes are associated with patient survival in intrahepatic cholangiocarcinoma. J Clin Pathol. 2014;67:229-34 pubmed 出版商
  • 免疫组化; 人类; 1:1500; 表 1
Lee P, Yau D, Lau P, Chan J. Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess. Int J Surg Pathol. 2014;22:286-90 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400; 表 4
Lee S, Kim H, Kim W, Han H, Lim S, Kim W, et al. Genetic alteration and immunohistochemical staining patterns of ovarian high-grade serous adenocarcinoma with special emphasis on p53 immnnostaining pattern. Pathol Int. 2013;63:252-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 图 1
Shi Y, Wu H, Zhang M, Ding L, Meng F, Fan X. Expression of the epithelial-mesenchymal transition-related proteins and their clinical significance in lung adenocarcinoma. Diagn Pathol. 2013;8:89 pubmed 出版商
  • 免疫组化; 人类; 1:150; 图 2
Min H, Lee C, Jung K. Correlation of immunohistochemical markers and BRAF mutation status with histological variants of papillary thyroid carcinoma in the Korean population. J Korean Med Sci. 2013;28:534-41 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Qiu H, Zhang L, Ren C, Zeng Z, Wu W, Luo H, et al. Targeting CDH17 suppresses tumor progression in gastric cancer by downregulating Wnt/β-catenin signaling. PLoS ONE. 2013;8:e56959 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:75; 图 2
Vasconcelos Nóbrega C, Costa C, Vala H, Colaco A, Santos L, Lopes C, et al. E-cadherin and ?-catenin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in mice. Urol Int. 2013;91:462-6 pubmed 出版商
  • 免疫组化; 人类; 1:100; 表 1
Souazé F, Bou Hanna C, Kandel C, Leclair F, Devalliere J, Charreau B, et al. Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study. PLoS ONE. 2013;8:e55904 pubmed 出版商
  • 免疫组化; 人类; 1:3000; 图 1
Avoranta S, Korkeila E, Ristamäki R, Syrjanen K, Carpén O, Pyrhönen S, et al. ALDH1 expression indicates chemotherapy resistance and poor outcome in node-negative rectal cancer. Hum Pathol. 2013;44:966-74 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Wang Q, Lin J, Chan S, Lin J. The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development. Dev Biol. 2013;374:264-80 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:250; 图 6
Carlsson E, Krohn K, Ovaska K, Lindberg P, Häyry V, Maliniemi P, et al. Neuron navigator 3 alterations in nervous system tumors associate with tumor malignancy grade and prognosis. Genes Chromosomes Cancer. 2013;52:191-201 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
  • 免疫印迹; 人类; 图 3
Langer M, Duggan E, Booth J, Patel V, Zander R, Silasi Mansat R, et al. Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function. Infect Immun. 2012;80:4374-87 pubmed 出版商
  • 免疫组化; 小鼠; 1:600
Gil da Costa R, Oliveira P, Bastos M, Lopes C, Lopes C. Ptaquiloside-induced early-stage urothelial lesions show increased cell proliferation and intact ?-catenin and E-cadherin expression. Environ Toxicol. 2014;29:763-9 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4
Raposo C, Odorissi P, Oliveira A, Aoyama H, Ferreira C, Verinaud L, et al. Effect of Phoneutria nigriventer venom on the expression of junctional protein and P-gp efflux pump function in the blood-brain barrier. Neurochem Res. 2012;37:1967-81 pubmed 出版商
  • 免疫组化; 人类; 图 2
Zhang J, Liang Z, Gao J, Luo Y, Liu T. Pulmonary adenocarcinoma with a micropapillary pattern: a clinicopathological, immunophenotypic and molecular analysis. Histopathology. 2011;59:1204-14 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Jin G, Bausch D, Knightly T, Liu Z, Li Y, Liu B, et al. Histone deacetylase inhibitors enhance endothelial cell sprouting angiogenesis in vitro. Surgery. 2011;150:429-35 pubmed 出版商
  • 免疫印迹; 人类; 1:250; 图 2
Kolegraff K, Nava P, Laur O, Parkos C, Nusrat A. Characterization of full-length and proteolytic cleavage fragments of desmoglein-2 in native human colon and colonic epithelial cell lines. Cell Adh Migr. 2011;5:306-14 pubmed
  • 免疫组化; 猕猴; 图 3
Hirt B, Gleiser C, Eckhard A, Mack A, Muller M, Wolburg H, et al. All functional aquaporin-4 isoforms are expressed in the rat cochlea and contribute to the formation of orthogonal arrays of particles. Neuroscience. 2011;189:79-92 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 4
  • 免疫印迹; 小鼠; 1:1000; 图 4
MARCIANO D, BRAKEMAN P, Lee C, Spivak N, Eastburn D, Bryant D, et al. p120 catenin is required for normal renal tubulogenesis and glomerulogenesis. Development. 2011;138:2099-109 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1
Im M, Kim D, Park J, Chung H, Lee Y, Kim C, et al. Alteration of the ?-catenin pathway in spiradenoma. J Cutan Pathol. 2011;38:657-62 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8
Li J, Swope D, Raess N, Cheng L, Muller E, Radice G. Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling. Mol Cell Biol. 2011;31:1134-44 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Yong Jiang -, Huawei Liu -, Hu Long -, Yingying Yang -, Dianying Liao -, Xiuhui Zhang -. Goblet cell carcinoid of the appendix: a clinicopathological and immunohistochemical study of 26 cases from southwest china. Int J Surg Pathol. 2010;18:488-92 pubmed 出版商
  • 免疫印迹; 人类; 图 s7
Tonge P, Andrews P. Retinoic acid directs neuronal differentiation of human pluripotent stem cell lines in a non-cell-autonomous manner. Differentiation. 2010;80:20-30 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Huvila J, Brandt A, Rojas C, Pasanen S, Talve L, Hirsimäki P, et al. Gene expression profiling of endometrial adenocarcinomas reveals increased apolipoprotein E expression in poorly differentiated tumors. Int J Gynecol Cancer. 2009;19:1226-31 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:300; 表 2
Gil da Costa R, Santos M, Amorim I, Lopes C, Pereira P, Faustino A. An immunohistochemical study of feline endometrial adenocarcinoma. J Comp Pathol. 2009;140:254-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Patriarca C, Colombo P, Pio Taronna A, Wesseling J, Franchi G, Guddo F, et al. Cell discohesion and multifocality of carcinoma in situ of the bladder: new insight from the adhesion molecule profile (e-cadherin, Ep-CAM, and MUC1). Int J Surg Pathol. 2009;17:99-106 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Elzagheid A, Buhmeida A, Korkeila E, Collan Y, Syrjanen K, Pyrhonen S. Nuclear beta-catenin expression as a prognostic factor in advanced colorectal carcinoma. World J Gastroenterol. 2008;14:3866-71 pubmed
  • 免疫组化-石蜡切片; 人类; 1:200
Buhmeida A, Elzagheid A, Algars A, Collan Y, Syrjanen K, Pyrhonen S. Expression of the cell-cell adhesion molecule beta-catenin in colorectal carcinomas and their metastases. APMIS. 2008;116:1-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Hervieu V, Lombard Bohas C, Dumortier J, Boillot O, Scoazec J. Primary acinar cell carcinoma of the liver. Virchows Arch. 2008;452:337-41 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:1500; 图 2
Reichel O, Mayr D, Durst F, Berghaus A. E-cadherin but not beta-catenin expression is decreased in laryngeal biopsies from patients with laryngopharyngeal reflux. Eur Arch Otorhinolaryngol. 2008;265:937-42 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 3
Lim S, Lim K, Giuliano R, Federoff H. Temporal and spatial localization of nectin-1 and l-afadin during synaptogenesis in hippocampal neurons. J Comp Neurol. 2008;507:1228-44 pubmed 出版商
  • 免疫组化; 鸡; 1:100; 图 2H
Thompson J, Wong L, Lau P, Bannigan J. Adherens junction breakdown in the periderm following cadmium administration in the chick embryo: distribution of cadherins and associated molecules. Reprod Toxicol. 2008;25:39-46 pubmed
  • 免疫组化; 犬; 1:100
Gama A, Paredes J, Gartner F, Alves A, Schmitt F. Expression of E-cadherin, P-cadherin and beta-catenin in canine malignant mammary tumours in relation to clinicopathological parameters, proliferation and survival. Vet J. 2008;177:45-53 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100
  • 免疫细胞化学; 人类; 1:100
Huang D, Casale G, Tian J, Wehbi N, Abrahams N, Kaleem Z, et al. Quantitative fluorescence imaging analysis for cancer biomarker discovery: application to beta-catenin in archived prostate specimens. Cancer Epidemiol Biomarkers Prev. 2007;16:1371-81 pubmed
  • 免疫组化-石蜡切片; 人类; 图 2
Mahomed F, Altini M, Meer S. Altered E-cadherin/beta-catenin expression in oral squamous carcinoma with and without nodal metastasis. Oral Dis. 2007;13:386-92 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100; 图 2
Canavese G, Bernardi A, Candelaresi G, Lovadina P, Amerio S, Rossetti V, et al. Expression of the E-cadherin-catenins complex in sentinel node is related to tumor morphology but not to spread to nonsentinel nodes. Pathol Res Pract. 2007;203:517-23 pubmed
  • 免疫组化-石蜡切片; 人类; 图 4
De Matos A, Lopes C, Faustino A, Carvalheira J, Rutteman G, Gärtner M. E-cadherin, beta-catenin, invasion and lymph node metastases in canine malignant mammary tumours. APMIS. 2007;115:327-34 pubmed
  • 免疫印迹; 小鼠; 1:1000
Chang M, Boulden J, Sutanto Ward E, DuHadaway J, Soler A, Muller A, et al. Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression. Cancer Res. 2007;67:100-7 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:400
Gritli Linde A, Hallberg K, Harfe B, Reyahi A, Kannius Janson M, Nilsson J, et al. Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell. 2007;12:99-112 pubmed
  • 免疫组化; 人类; 1:250
Tiemann K, Kosmahl M, Ohlendorf J, Krams M, Kloppel G. Solid pseudopapillary neoplasms of the pancreas are associated with FLI-1 expression, but not with EWS/FLI-1 translocation. Mod Pathol. 2006;19:1409-13 pubmed
  • 免疫细胞化学; 犬
Larre I, Ponce A, Fiorentino R, Shoshani L, Contreras R, Cereijido M. Contacts and cooperation between cells depend on the hormone ouabain. Proc Natl Acad Sci U S A. 2006;103:10911-6 pubmed
  • 免疫组化; 人类; 1:400; 图 1
Goldstein N. Small colonic microsatellite unstable adenocarcinomas and high-grade epithelial dysplasias in sessile serrated adenoma polypectomy specimens: a study of eight cases. Am J Clin Pathol. 2006;125:132-45 pubmed
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1
Lee J, Choi K, Lee S, Gye M. Expression of beta-catenin in human testes with spermatogenic defects. Arch Androl. 2005;51:271-6 pubmed
  • 免疫组化-冰冻切片; 人类
Kaplan S, Gard J, Protonotarios N, Tsatsopoulou A, Spiliopoulou C, Anastasakis A, et al. Remodeling of myocyte gap junctions in arrhythmogenic right ventricular cardiomyopathy due to a deletion in plakoglobin (Naxos disease). Heart Rhythm. 2004;1:3-11 pubmed
  • 免疫组化-石蜡切片; 小鼠
Knudsen K, Sauer C, Johnson K, Wheelock M. Effect of N-cadherin misexpression by the mammary epithelium in mice. J Cell Biochem. 2005;95:1093-107 pubmed
  • 免疫细胞化学; 小鼠; 图 3
  • 免疫印迹; 小鼠; 图 4A-B
Modarresi R, Lafond T, Roman Blas J, Danielson K, Tuan R, Seghatoleslami M. N-cadherin mediated distribution of beta-catenin alters MAP kinase and BMP-2 signaling on chondrogenesis-related gene expression. J Cell Biochem. 2005;95:53-63 pubmed
  • 免疫组化-石蜡切片; 人类; 图 2
Ramburan A, Oladiran F, Smith C, Hadley G, Govender D. Microsatellite analysis of the adenomatous polyposis coli (APC) gene and immunoexpression of beta catenin in nephroblastoma: a study including 83 cases treated with preoperative chemotherapy. J Clin Pathol. 2005;58:44-50 pubmed
  • 免疫组化-石蜡切片; 人类; 1:250
Sedivy R, Peters K, Kloppel G. Osteopontin expression in ductal adenocarcinomas and undifferentiated carcinomas of the pancreas. Virchows Arch. 2005;446:41-5 pubmed
  • 免疫组化-冰冻切片; 人类; 1:2000
  • 免疫组化-石蜡切片; 人类; 1:2000
Honecker F, Kersemaekers A, Molier M, Van Weeren P, Stoop H, de Krijger R, et al. Involvement of E-cadherin and beta-catenin in germ cell tumours and in normal male fetal germ cell development. J Pathol. 2004;204:167-74 pubmed
  • 免疫组化-石蜡切片; 人类
Lyakhovitsky A, Barzilai A, Fogel M, Trau H, Huszar M. Expression of e-cadherin and beta-catenin in cutaneous squamous cell carcinoma and its precursors. Am J Dermatopathol. 2004;26:372-8 pubmed
  • 免疫组化-石蜡切片; 人类; 1:250; 表 1
Marques F, Fonsechi Carvasan G, de Angelo Andrade L, Bottcher Luiz F. Immunohistochemical patterns for alpha- and beta-catenin, E- and N-cadherin expression in ovarian epithelial tumors. Gynecol Oncol. 2004;94:16-24 pubmed
  • 免疫组化-石蜡切片; 人类; 1:750; 图 3
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产品信息
产品类型 :
抗体
产品名称 :
beta连环蛋白单克隆抗体(猫-5H10)
目录# :
13-8400
规格 :
100微克
价格 :
美国455.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
鸡, 人类, 小鼠
应用 :
Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
物种 :
鸡, 人类, 小鼠
克隆 :
猫-5H10
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless. The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis. Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats. A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development. In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation. The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.
免疫原 :
Fusion protein consisting of the maltose binding protein fused to a 100 amino acid segment of the C-terminus of chicken beta-Catenin.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
别名 :
armadillo; armadillo homolog; Bcatenin; b-catenin; beta 1 88kDa; beta catenin; Betacatenin; beta-catenin; beta-catenin 1; Bfc; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin ß 1; Catenin ß1; Catnb; CHBCAT; CTNB1; CTNNB; ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; ß catenin; ßcatenin
更多信息或购买 :
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公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国