产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
alpha Catenin Monoclonal Antibody (alpha-CAT-7A4)
目录 :
13-9700
规格 :
100微克
价格 :
美国449.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
甲猫
反应物种 :
人类, 小鼠, 大鼠, 鸡
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 31
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠; 1:100
Li N, Mruk D, Wong C, Lee W, Han D, Cheng C. Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis. FASEB J. 2015;29:3788-805 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Figueira A, Gomes C, Vilhena H, Miranda S, Carvalheira J, de Matos A, et al. Characterization of α-, β- and p120-Catenin Expression in Feline Mammary Tissues and their Relation with E- and P-Cadherin. Anticancer Res. 2015;35:3361-9 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100
da Silva S, Morand G, Alobaid F, Hier M, Mlynarek A, Alaoui Jamali M, et al. Epithelial-mesenchymal transition (EMT) markers have prognostic impact in multiple primary oral squamous cell carcinoma. Clin Exp Metastasis. 2015;32:55-63 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Qian X, Mruk D, Cheng C. Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*. PLoS ONE. 2013;8:e60656 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 s5
  • 免疫组化; 小鼠; 1:100; 图 s3h
Gladden A, Hebert A, Schneeberger E, McClatchey A. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010;19:727-39 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Patriarca C, Colombo P, Pio Taronna A, Wesseling J, Franchi G, Guddo F, et al. Cell discohesion and multifocality of carcinoma in situ of the bladder: new insight from the adhesion molecule profile (e-cadherin, Ep-CAM, and MUC1). Int J Surg Pathol. 2009;17:99-106 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠
Uehara K, Uehara A. Localization of claudin-5 and ZO-1 in rat spleen sinus endothelial cells. Histochem Cell Biol. 2008;129:95-103 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Canavese G, Bernardi A, Candelaresi G, Lovadina P, Amerio S, Rossetti V, et al. Expression of the E-cadherin-catenins complex in sentinel node is related to tumor morphology but not to spread to nonsentinel nodes. Pathol Res Pract. 2007;203:517-23 pubmed
  • 免疫组化-冰冻切片; 小鼠; 1:100
Akins M, Greer C. Axon behavior in the olfactory nerve reflects the involvement of catenin-cadherin mediated adhesion. J Comp Neurol. 2006;499:979-89 pubmed
  • 免疫细胞化学; 小鼠; 图 1
  • 免疫印迹; 小鼠; 图 1
Kim Y, Sauer C, Testa K, Wahl J, Svoboda R, Johnson K, et al. Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex. J Cell Sci. 2005;118:3883-94 pubmed
  • 免疫组化-冰冻切片; 人类
Kaplan S, Gard J, Protonotarios N, Tsatsopoulou A, Spiliopoulou C, Anastasakis A, et al. Remodeling of myocyte gap junctions in arrhythmogenic right ventricular cardiomyopathy due to a deletion in plakoglobin (Naxos disease). Heart Rhythm. 2004;1:3-11 pubmed
  • 免疫组化-石蜡切片; 人类; 1:50; 表 1
Marques F, Fonsechi Carvasan G, de Angelo Andrade L, Bottcher Luiz F. Immunohistochemical patterns for alpha- and beta-catenin, E- and N-cadherin expression in ovarian epithelial tumors. Gynecol Oncol. 2004;94:16-24 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100; 表 4
Song S, Kim S, Kim D, Son H, Rhee J, Kim Y. Abnormal expression of E-cadherin in early gastric carcinoma: its relationship with macroscopic growth patterns and catenin alpha and beta. J Clin Gastroenterol. 2004;38:252-9 pubmed
  • 免疫印迹; 小鼠; 图 8
Carothers A, Melstrom K, Mueller J, Weyant M, Bertagnolli M. Progressive changes in adherens junction structure during intestinal adenoma formation in Apc mutant mice. J Biol Chem. 2001;276:39094-102 pubmed
  • 免疫细胞化学; 人类
Allport J, Muller W, Luscinskas F. Monocytes induce reversible focal changes in vascular endothelial cadherin complex during transendothelial migration under flow. J Cell Biol. 2000;148:203-16 pubmed
  • 免疫组化-冰冻切片; 人类
Spirin K, Ljubimov A, Castellon R, Wiedoeft O, Marano M, Sheppard D, et al. Analysis of gene expression in human bullous keratopathy corneas containing limiting amounts of RNA. Invest Ophthalmol Vis Sci. 1999;40:3108-15 pubmed
  • 免疫印迹; 人类
de Boer C, van Dorst E, van Krieken H, Jansen van Rhijn C, Warnaar S, Fleuren G, et al. Changing roles of cadherins and catenins during progression of squamous intraepithelial lesions in the uterine cervix. Am J Pathol. 1999;155:505-15 pubmed
Ouyang X, Dong C, Ubogu E. In situ molecular characterization of endoneurial microvessels that form the blood-nerve barrier in normal human adult peripheral nerves. J Peripher Nerv Syst. 2019;24:195-206 pubmed 出版商
Anchan A, Kalogirou Baldwin P, Johnson R, Kho D, Joseph W, Hucklesby J, et al. Real-Time Measurement of Melanoma Cell-Mediated Human Brain Endothelial Barrier Disruption Using Electric Cell-Substrate Impedance Sensing Technology. Biosensors (Basel). 2019;9: pubmed 出版商
Domke L, Franke W. The cell-cell junctions of mammalian testes: II. The lamellar smooth muscle monolayer cells of the peritubular wall are laterally connected by vertical adherens junctions-a novel architectonic cell-cell junction system. Cell Tissue Res. 2019;375:451-482 pubmed 出版商
Chen H, Lu R, Zhang Y, Sun J. Vitamin D Receptor Deletion Leads to the Destruction of Tight and Adherens Junctions in Lungs. Tissue Barriers. 2018;6:1-13 pubmed 出版商
Robilliard L, Kho D, Johnson R, Anchan A, O Carroll S, Graham E. The Importance of Multifrequency Impedance Sensing of Endothelial Barrier Formation Using ECIS Technology for the Generation of a Strong and Durable Paracellular Barrier. Biosensors (Basel). 2018;8: pubmed 出版商
Vite A, Zhang C, Yi R, Emms S, Radice G. α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart. Development. 2018;145: pubmed 出版商
Palladino S, Helton E, Jain P, Dong C, Crowley M, Crossman D, et al. The Human Blood-Nerve Barrier Transcriptome. Sci Rep. 2017;7:17477 pubmed 出版商
Advedissian T, Proux Gillardeaux V, Nkosi R, Peyret G, Nguyen T, Poirier F, et al. E-cadherin dynamics is regulated by galectin-7 at epithelial cell surface. Sci Rep. 2017;7:17086 pubmed 出版商
Jenkins E, Caputo M, Angelini G, Ghorbel M. Chronic hypoxia down-regulates tight junction protein ZO-2 expression in children with cyanotic congenital heart defect. ESC Heart Fail. 2016;3:131-137 pubmed
Qian X, Mruk D, Wong E, Lie P, Cheng C. Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes. Endocrinology. 2013;154:1907-20 pubmed 出版商
Troyanovsky R, Klingelhofer J, Troyanovsky S. ?-Catenin contributes to the strength of E-cadherin-p120 interactions. Mol Biol Cell. 2011;22:4247-55 pubmed 出版商
Gould Rothberg B, Berger A, Molinaro A, Subtil A, Krauthammer M, Camp R, et al. Melanoma prognostic model using tissue microarrays and genetic algorithms. J Clin Oncol. 2009;27:5772-80 pubmed 出版商
Jacquemier J, Ginestier C, Rougemont J, Bardou V, Charafe Jauffret E, Geneix J, et al. Protein expression profiling identifies subclasses of breast cancer and predicts prognosis. Cancer Res. 2005;65:767-79 pubmed
Scheffers M, Le H, van der Bent P, Leonhard W, Prins F, Spruit L, et al. Distinct subcellular expression of endogenous polycystin-2 in the plasma membrane and Golgi apparatus of MDCK cells. Hum Mol Genet. 2002;11:59-67 pubmed
产品信息
产品类型 :
抗体
产品名称 :
alpha Catenin Monoclonal Antibody (alpha-CAT-7A4)
目录# :
13-9700
规格 :
100微克
价格 :
美国449.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
鸡, 人类, 小鼠, 大鼠, 非洲爪蛙
应用 :
ELISA: Assay-dependent, Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 1:250, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:250
物种 :
鸡, 人类, 小鼠, 大鼠, 非洲爪蛙
克隆 :
甲猫
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
Alpha catenin is a member of the b-catenin family of cytosolic proteins. Alpha catenin interacts with N-cadherin and b-catenin on the cytosolic side of adherins junctions to mediate the interaction with the actin cytoskeleton. Alpha catenin is a homodimer in solution, but dissociates to form a 1:1 heterodimer with b-catenin in order to interact with cadherins. It also regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Alpha catenin also functions in the control of the startle modulation.
免疫原 :
Synthetic peptide derived from the C-terminus of mouse alpha-catenin.
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 1:250, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:250
别名 :
102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI481747; AI988031; alpha E catenin; alpha E-catenin; Alpha N-catenin; alpha(E)-catenin; alpha(N)-catenin; alpha-catenin; alpha-catenin-related protein; alpha-E-catenin; alphaE-catenin; alpha-N-catenin; alphaN-catenin; cadherin associated protein; Cadherin-associated protein; cadherin-associated protein, related; cancer/testis antigen 114; CAP102; CAPR; CAP-R; catenin; catenin (cadherin associated protein), alpha 1; catenin (cadherin associated protein), alpha 2; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin (cadherin-associated protein), alpha 2; catenin alpha 1; catenin alpha 2; Catenin alpha1; catenin alpha-1; Catenin alpha2; Catenin alpha-2; catenin, alpha 1; Catenin-alpha1; Catenin-alpha2; Catna; Catna1; Catna2; cdf; cerebellar deficient folia; chp; CT114; CTNNA1; Ctnna2; CTNR; FLJ36832; FLJ52416; HGNC:2509; MDPT2; Neural alpha-catenin; NY-REN-13 antigen; renal carcinoma antigen NY-REN-13
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国