产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD3e Monoclonal Antibody (145-2C11), eBioscience™
目录 :
14-0031-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
未共轭
克隆名称 :
145-2C11
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 1047
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:100
Jensen I, Jensen S, Sjaastad F, Gibson Corley K, Dileepan T, Griffith T, et al. Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200
Gao L, Li B, Wang J, Shen D, Yang M, Sun R, et al. Activation of Liver X Receptor α Sensitizes Mice to T-Cell Mediated Hepatitis. Hepatol Commun. 2020;4:1664-1679 pubmed 出版商
  • 流式细胞仪; 小鼠
Myers D, Abram C, Wildes D, Belwafa A, Welsh A, Schulze C, et al. Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity. Front Immunol. 2020;11:576310 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
  • 免疫组化; 小鼠
Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed 出版商
  • 流式细胞仪; 人类; 1:100; 图 6a
Gao M, Wang T, Ji L, Bai S, Tian L, Song H. Therapy With Carboplatin and Anti-PD-1 Antibodies Before Surgery Demonstrates Sustainable Anti-Tumor Effects for Secondary Cancers in Mice With Triple-Negative Breast Cancer. Front Immunol. 2020;11:366 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Tizian C, Lahmann A, Hölsken O, Cosovanu C, Kofoed Branzk M, Heinrich F, et al. c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3c
Park M, Kim H, Lee H, Zabel B, Bae Y. Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection. Sci Adv. 2020;6:eaax8820 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:50; 图 e1a
Vagnozzi R, Maillet M, Sargent M, Khalil H, Johansen A, Schwanekamp J, et al. An acute immune response underlies the benefit of cardiac stem cell therapy. Nature. 2020;577:405-409 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 e9g
Hang S, Paik D, Yao L, Kim E, Jamma T, Lu J, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019;576:143-148 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 2e
Kobayakawa K, Ohkawa Y, Yoshizaki S, Tamaru T, Saito T, Kijima K, et al. Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. Sci Adv. 2019;5:eaav5086 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:1000; 图 e2j, e8a
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Kumar P, Rajasekaran K, Nanbakhsh A, Gorski J, Thakar M, Malarkannan S. IL-27 promotes NK cell effector functions via Maf-Nrf2 pathway during influenza infection. Sci Rep. 2019;9:4984 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3b
Nayar S, Campos J, Smith C, Iannizzotto V, Gardner D, Colafrancesco S, et al. Phosphatidylinositol 3-kinase delta pathway: a novel therapeutic target for Sjögren's syndrome. Ann Rheum Dis. 2019;78:249-260 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6b
Er J, Koean R, Ding J. Loss of T-bet confers survival advantage to influenza-bacterial superinfection. EMBO J. 2019;38: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Lee Y, Ju J, Shon W, Oh S, Min C, Kang M, et al. Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD. Immune Netw. 2018;18:e44 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6d
Stephens J, Bailey J, Hang H, Rittell V, Dietrich M, Mynatt R, et al. Adipose Tissue Dysfunction Occurs Independently of Obesity in Adipocyte-Specific Oncostatin Receptor Knockout Mice. Obesity (Silver Spring). 2018;26:1439-1447 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Gu C, Borjabad A, Hadas E, Kelschenbach J, Kim B, Chao W, et al. EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment. PLoS Pathog. 2018;14:e1007061 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1e
Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s5d
Donaldson G, Ladinsky M, Yu K, Sanders J, Yoo B, Chou W, et al. Gut microbiota utilize immunoglobulin A for mucosal colonization. Science. 2018;360:795-800 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Kling J, Jordan M, Pitt L, Meiners J, Thanh Tran T, Tran L, et al. Temporal Regulation of Natural Killer T Cell Interferon Gamma Responses by β-Catenin-Dependent and -Independent Wnt Signaling. Front Immunol. 2018;9:483 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4a
Metghalchi S, Vandestienne M, Haddad Y, Esposito B, Dairou J, Tedgui A, et al. Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet. PLoS ONE. 2018;13:e0193737 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 1b
A Verghese D, Demir M, Chun N, Fribourg M, Cravedi P, Llaudó I, et al. T Cell Expression of C5a Receptor 2 Augments Murine Regulatory T Cell (TREG) Generation and TREG-Dependent Cardiac Allograft Survival. J Immunol. 2018;200:2186-2198 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
Perry C, Muñoz Rojas A, Meeth K, Kellman L, Amezquita R, Thakral D, et al. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J Exp Med. 2018;215:877-893 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s11c
Dejea C, Fathi P, Craig J, Boleij A, Taddese R, Geis A, et al. Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria. Science. 2018;359:592-597 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4c
Vo L, Kinney M, Liu X, Zhang Y, Barragan J, Sousa P, et al. Regulation of embryonic haematopoietic multipotency by EZH1. Nature. 2018;553:506-510 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3b
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2d
Guarnerio J, Mendez L, Asada N, Menon A, Fung J, Berry K, et al. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nat Commun. 2018;9:66 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Burrack A, Malhotra D, Dileepan T, Osum K, Swanson L, Fife B, et al. Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides. J Immunol. 2018;200:477-482 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7a
Kortlever R, Sodir N, Wilson C, Burkhart D, Pellegrinet L, Brown Swigart L, et al. Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. Cell. 2017;171:1301-1315.e14 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Cole C, Russler Germain D, Ketkar S, Verdoni A, Smith A, Bangert C, et al. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies. J Clin Invest. 2017;127:3657-3674 pubmed 出版商
  • 免疫组化; 小鼠; 图 s3b
Funken D, Ishikawa Ankerhold H, Uhl B, Lerchenberger M, Rentsch M, Mayr D, et al. In situ targeting of dendritic cells sets tolerogenic environment and ameliorates CD4+ T-cell response in the postischemic liver. FASEB J. 2017;31:4796-4808 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Ma S, Wan X, Deng Z, Shi L, Hao C, Zhou Z, et al. Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs. J Exp Med. 2017;214:1471-1491 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 9
Tewes S, Gueler F, Chen R, Gutberlet M, Jang M, Meier M, et al. Functional MRI for characterization of renal perfusion impairment and edema formation due to acute kidney injury in different mouse strains. PLoS ONE. 2017;12:e0173248 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1g
Goverse G, Molenaar R, Macia L, Tan J, Erkelens M, Konijn T, et al. Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells. J Immunol. 2017;198:2172-2181 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 4a
Larabee C, Desai S, Agasing A, Georgescu C, Wren J, Axtell R, et al. Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis. Mol Vis. 2016;22:1503-1513 pubmed
  • 流式细胞仪; 小鼠; 图 3
Bieber K, Witte M, Sun S, Hundt J, Kalies K, Dräger S, et al. T cells mediate autoantibody-induced cutaneous inflammation and blistering in epidermolysis bullosa acquisita. Sci Rep. 2016;6:38357 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Moroishi T, Hayashi T, Pan W, Fujita Y, Holt M, Qin J, et al. The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity. Cell. 2016;167:1525-1539.e17 pubmed 出版商
  • 流式细胞仪; 小鼠
Ramirez Carrozzi V, Sambandam A, Zhou M, Yan D, Kang J, Wu X, et al. Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone. J Allergy Clin Immunol. 2017;139:705-708.e6 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 3
Hrdinka M, Sudan K, Just S, Drobek A, Stepanek O, Schluter D, et al. Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice. PLoS ONE. 2016;11:e0162863 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 S3
Uhde A, Herder V, Akram Khan M, Ciurkiewicz M, Schaudien D, Teich R, et al. Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL Mice. PLoS ONE. 2016;11:e0161883 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
He C, Duan X, Guo N, Chan C, Poon C, Weichselbaum R, et al. Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy. Nat Commun. 2016;7:12499 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Terashima A, Okamoto K, Nakashima T, Akira S, Ikuta K, Takayanagi H. Sepsis-Induced Osteoblast Ablation Causes Immunodeficiency. Immunity. 2016;44:1434-43 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3f
Stein S, Mack E, Rome K, Pajcini K, Ohtani T, Xu L, et al. Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL. PLoS ONE. 2016;11:e0155408 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4
Brandstätter O, Schanz O, Vorac J, König J, Mori T, Maruyama T, et al. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016;6:26091 pubmed 出版商
  • 抑制或激活实验; 小鼠; 5 ug/ml; 图 2
Swamy M, Pathak S, Grzes K, Damerow S, Sinclair L, van Aalten D, et al. Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy. Nat Immunol. 2016;17:712-20 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2d
Song Z, Li Z, Li D, Fang W, Liu H, Yang D, et al. Seminal plasma induces inflammation in the uterus through the ?? T/IL-17 pathway. Sci Rep. 2016;6:25118 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4
Kabat A, Harrison O, Riffelmacher T, Moghaddam A, Pearson C, Laing A, et al. The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. elife. 2016;5:e12444 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4
Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100
Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Caballero Franco C, Guma M, Choo M, Sano Y, Enzler T, Karin M, et al. Epithelial Control of Gut-Associated Lymphoid Tissue Formation through p38?-Dependent Restraint of NF-?B Signaling. J Immunol. 2016;196:2368-76 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4a
Jabara H, Boyden S, Chou J, Ramesh N, Massaad M, Benson H, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016;48:74-8 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 1
Schachtner H, Weimershaus M, Stache V, Plewa N, Legler D, Höpken U, et al. Loss of Gadkin Affects Dendritic Cell Migration In Vitro. PLoS ONE. 2015;10:e0143883 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Zhong C, Cui K, Wilhelm C, Hu G, Mao K, Belkaid Y, et al. Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment. Nat Immunol. 2016;17:169-78 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Stachtea X, Tykesson E, van Kuppevelt T, Feinstein R, Malmström A, Reijmers R, et al. Dermatan Sulfate-Free Mice Display Embryological Defects and Are Neonatal Lethal Despite Normal Lymphoid and Non-Lymphoid Organogenesis. PLoS ONE. 2015;10:e0140279 pubmed 出版商
  • 流式细胞仪; 小鼠
Li S, Dislich B, Brakebusch C, Lichtenthaler S, Brocker T. Control of Homeostasis and Dendritic Cell Survival by the GTPase RhoA. J Immunol. 2015;195:4244-56 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5b
Guo L, Huang Y, Chen X, Hu Li J, Urban J, Paul W. Innate immunological function of TH2 cells in vivo. Nat Immunol. 2015;16:1051-9 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 1f
  • 流式细胞仪; 小鼠; 1 ug/ml; 图 1b
Nakatsukasa H, Zhang D, Maruyama T, Chen H, Cui K, Ishikawa M, et al. The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. Nat Immunol. 2015;16:1077-84 pubmed 出版商
  • 抑制或激活实验; 小鼠
Pearce V, Bouabe H, MacQueen A, Carbonaro V, Okkenhaug K. PI3Kδ Regulates the Magnitude of CD8+ T Cell Responses after Challenge with Listeria monocytogenes. J Immunol. 2015;195:3206-17 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Jiang Y, Gao Q, Wang L, Guo C, Zhu F, Wang B, et al. Deficiency of programmed cell death 4 results in increased IL-10 expression by macrophages and thereby attenuates atherosclerosis in hyperlipidemic mice. Cell Mol Immunol. 2016;13:524-34 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Hernández P, Mahlakõiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F, et al. Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection. Nat Immunol. 2015;16:698-707 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2
Chen H, Sun J, Huang Z, Hou H, Arcilla M, Rakhilin N, et al. Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting. Nat Biotechnol. 2015;33:656-60 pubmed 出版商
  • 流式细胞仪; 小鼠
Berent Maoz B, Montecino Rodriguez E, Fice M, Casero D, Seet C, Crooks G, et al. The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2). PLoS ONE. 2015;10:e0125414 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:12
Siegemund S, Shepherd J, Xiao C, Sauer K. hCD2-iCre and Vav-iCre mediated gene recombination patterns in murine hematopoietic cells. PLoS ONE. 2015;10:e0124661 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Kim P, Nakano H, Das P, Chen M, Rowe R, Chou S, et al. Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. J Exp Med. 2015;212:633-48 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 8
Van Den Ham K, Shio M, Rainone A, Fournier S, Krawczyk C, Olivier M. Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis. PLoS ONE. 2015;10:e0118451 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 1
Feuerstein R, Seidl M, Prinz M, Henneke P. MyD88 in macrophages is critical for abscess resolution in staphylococcal skin infection. J Immunol. 2015;194:2735-45 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Zhan R, Han Q, Zhang C, Tian Z, Zhang J. Toll-Like receptor 2 (TLR2) and TLR9 play opposing roles in host innate immunity against Salmonella enterica serovar Typhimurium infection. Infect Immun. 2015;83:1641-9 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Sell S, Dietz M, Schneider A, Holtappels R, Mach M, Winkler T. Control of murine cytomegalovirus infection by γδ T cells. PLoS Pathog. 2015;11:e1004481 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Hu W, Dooley J, Chung S, Chandramohan D, Cimmino L, Mukherjee S, et al. miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 2015;125:2206-16 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Das D, Feng Y, Mallis R, Li X, Keskin D, Hussey R, et al. Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime. Proc Natl Acad Sci U S A. 2015;112:1517-22 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Karsten C, Laumonnier Y, Eurich B, Ender F, Bröker K, Roy S, et al. Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse. J Immunol. 2015;194:1841-55 pubmed 出版商
  • 流式细胞仪; 小鼠
Spada R, Rojas J, Pérez Yagüe S, Mulens V, Cannata Ortiz P, Bragado R, et al. NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery. J Leukoc Biol. 2015;97:583-98 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Sullivan B, Teijaro J, de la Torre J, Oldstone M. Early virus-host interactions dictate the course of a persistent infection. PLoS Pathog. 2015;11:e1004588 pubmed 出版商
  • 流式细胞仪; 小鼠; 表 1
Djukic M, Sostmann N, Bertsch T, Mecke M, Nessler S, Manig A, et al. Vitamin D deficiency decreases survival of bacterial meningoencephalitis in mice. J Neuroinflammation. 2015;12:208 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Krysiak K, Tibbitts J, Shao J, Liu T, Ndonwi M, Walter M. Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells. Exp Hematol. 2015;43:319-30.e10 pubmed 出版商
  • 抑制或激活实验; 小鼠; 1 ug/ml
Sakaguchi S, Hombauer M, Hassan H, Tanaka H, Yasmin N, Naoe Y, et al. A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells. J Leukoc Biol. 2015;97:635-44 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Ueno N, Lodoen M, Hickey G, Robey E, Coombes J. Toxoplasma gondii-infected natural killer cells display a hypermotility phenotype in vivo. Immunol Cell Biol. 2015;93:508-13 pubmed 出版商
  • 流式细胞仪; 小鼠
Karamitros D, Patmanidi A, Kotantaki P, Potocnik A, Bähr Ivacevic T, Benes V, et al. Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors. Development. 2015;142:70-81 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Kobold S, Steffen J, Chaloupka M, Grassmann S, Henkel J, Castoldi R, et al. Selective bispecific T cell recruiting antibody and antitumor activity of adoptive T cell transfer. J Natl Cancer Inst. 2015;107:364 pubmed 出版商
  • 流式细胞仪; 小鼠
Schwartz C, Turqueti Neves A, Hartmann S, Yu P, Nimmerjahn F, Voehringer D. Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion. Proc Natl Acad Sci U S A. 2014;111:E5169-77 pubmed 出版商
  • 抑制或激活实验; 小鼠; 1 ug/ml
  • 流式细胞仪; 小鼠; 1 ug/ml
Arndt B, Witkowski L, Ellwart J, Seissler J. CD8+ CD122+ PD-1- effector cells promote the development of diabetes in NOD mice. J Leukoc Biol. 2015;97:111-20 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 1e
Backer R, Helbig C, Gentek R, Kent A, Laidlaw B, Dominguez C, et al. A central role for Notch in effector CD8(+) T cell differentiation. Nat Immunol. 2014;15:1143-51 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Morales D, Monte K, Sun L, Struckhoff J, Agapov E, Holtzman M, et al. Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice. J Virol. 2015;89:337-49 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Edwards C, Best S, Gun S, Claser C, James K, de Oca M, et al. Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection. Eur J Immunol. 2015;45:130-41 pubmed 出版商
  • 流式细胞仪; 小鼠
Denton A, Roberts E, Linterman M, Fearon D. Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells. Proc Natl Acad Sci U S A. 2014;111:12139-44 pubmed 出版商
  • 流式细胞仪; 人类
Zhu Y, Knolhoff B, Meyer M, Nywening T, West B, Luo J, et al. CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Cancer Res. 2014;74:5057-69 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 流式细胞仪; 小鼠
Longman R, Diehl G, Victorio D, Huh J, Galan C, Miraldi E, et al. CX?CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J Exp Med. 2014;211:1571-83 pubmed 出版商
  • 流式细胞仪; 小鼠
Vogelzang A, Perdomo C, Zedler U, Kuhlmann S, Hurwitz R, Gengenbacher M, et al. Central memory CD4+ T cells are responsible for the recombinant Bacillus Calmette-Guérin ?ureC::hly vaccine's superior protection against tuberculosis. J Infect Dis. 2014;210:1928-37 pubmed 出版商
  • 流式细胞仪; 小鼠
Vanoaica L, Richman L, Jaworski M, Darshan D, Luther S, Kühn L. Conditional deletion of ferritin h in mice reduces B and T lymphocyte populations. PLoS ONE. 2014;9:e89270 pubmed 出版商
  • 抑制或激活实验; 小鼠
Bashour K, Gondarenko A, Chen H, Shen K, Liu X, Huse M, et al. CD28 and CD3 have complementary roles in T-cell traction forces. Proc Natl Acad Sci U S A. 2014;111:2241-6 pubmed 出版商
  • 抑制或激活实验; 小鼠
Yang C, Li J, Chiu L, Lan J, Chen D, Chuang H, et al. Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation. J Immunol. 2014;192:1547-57 pubmed 出版商
  • 免疫细胞化学; 小鼠
McGuire D, Rowse A, Li H, Peng B, Sestero C, Cashman K, et al. CD5 enhances Th17-cell differentiation by regulating IFN-? response and ROR?t localization. Eur J Immunol. 2014;44:1137-42 pubmed 出版商
  • 流式细胞仪; 小鼠
Griffiths K, Stylianou E, Poyntz H, Betts G, Fletcher H, McShane H. Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice. PLoS ONE. 2013;8:e78312 pubmed 出版商
  • 抑制或激活实验; 小鼠; 10 ug/ml
Kłossowicz M, Scirka B, Suchanek J, Marek Bukowiec K, Kisielow P, Aguado E, et al. Assessment of caspase mediated degradation of linker for activation of T cells (LAT) at a single cell level. J Immunol Methods. 2013;389:9-17 pubmed 出版商
  • 流式细胞仪; 小鼠
Golias J, Schwarzer M, Wallner M, Kverka M, Kozakova H, Srůtková D, et al. Heat-induced structural changes affect OVA-antigen processing and reduce allergic response in mouse model of food allergy. PLoS ONE. 2012;7:e37156 pubmed 出版商
  • 流式细胞仪; 小鼠
Chevrier S, Genton C, Malissen B, Malissen M, Acha Orbea H. Dominant Role of CD80-CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LAT(Y136F) CD4(+) T Cells. Front Immunol. 2012;3:27 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Ota N, Wong K, Valdez P, Zheng Y, Crellin N, Diehl L, et al. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nat Immunol. 2011;12:941-8 pubmed 出版商
  • 流式细胞仪; 小鼠
Deswal S, Schulze A, Hofer T, Schamel W. Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networks. PLoS ONE. 2011;6:e22928 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Yan S, Wang L, Liu N, Wang Y, Chu Y. Critical role of interleukin-17/interleukin-17 receptor axis in mediating Con A-induced hepatitis. Immunol Cell Biol. 2012;90:421-8 pubmed 出版商
  • 流式细胞仪; 小鼠
Tousif S, Singh Y, Prasad D, Sharma P, Van Kaer L, Das G. T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection. PLoS ONE. 2011;6:e19864 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Fahl S, Crittenden R, Allman D, Bender T. c-Myb is required for pro-B cell differentiation. J Immunol. 2009;183:5582-92 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Zumsteg A, Baeriswyl V, Imaizumi N, Schwendener R, Ruegg C, Christofori G. Myeloid cells contribute to tumor lymphangiogenesis. PLoS ONE. 2009;4:e7067 pubmed 出版商
  • 流式细胞仪; 小鼠
Hamada H, Garcia Hernandez M, Reome J, Misra S, Strutt T, McKinstry K, et al. Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J Immunol. 2009;182:3469-81 pubmed 出版商
  • 抑制或激活实验; 小鼠; 100 ng/ml
Sheng H, Wang Y, Jin Y, Zhang Q, Zhang Y, Wang L, et al. A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res. 2008;18:846-57 pubmed 出版商
  • 流式细胞仪; 小鼠
Jiang L, Yang P, He H, Li B, Lin X, Hou S, et al. Increased expression of Foxp3 in splenic CD8+ T cells from mice with anterior chamber-associated immune deviation. Mol Vis. 2007;13:968-74 pubmed
  • 抑制或激活实验; 小鼠
Sevigny C, Li L, Awad A, Huang L, McDuffie M, Linden J, et al. Activation of adenosine 2A receptors attenuates allograft rejection and alloantigen recognition. J Immunol. 2007;178:4240-9 pubmed
  • 流式细胞仪; 小鼠; 图 2
Xin K, Mizukami H, Urabe M, Toda Y, Shinoda K, Yoshida A, et al. Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells. J Virol. 2006;80:11899-910 pubmed
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 1
Geng H, Zhang G, Xiao H, Yuan Y, Li D, Zhang H, et al. HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma. Int J Cancer. 2006;118:2657-64 pubmed
  • 流式细胞仪; 小鼠; 图 5
Gupta R, Karpatkin S, Basch R. Hematopoiesis and stem cell renewal in long-term bone marrow cultures containing catalase. Blood. 2006;107:1837-46 pubmed
  • 流式细胞仪; 小鼠; 图 1
Krieg C, Han P, Stone R, Goularte O, Kaye J. Functional analysis of B and T lymphocyte attenuator engagement on CD4+ and CD8+ T cells. J Immunol. 2005;175:6420-7 pubmed
  • 免疫组化-冰冻切片; 小鼠
Takeuchi A, Usui Y, Takeuchi M, Hattori T, Kezuka T, Suzuki J, et al. CCR5-deficient mice develop experimental autoimmune uveoretinitis in the context of a deviant effector response. Invest Ophthalmol Vis Sci. 2005;46:3753-60 pubmed
  • 流式细胞仪; 小鼠
Irwin S, Izzo A, Dow S, Skeiky Y, Reed S, Alderson M, et al. Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein. Infect Immun. 2005;73:5809-16 pubmed
  • 抑制或激活实验; 小鼠
Nakae S, Suto H, Kakurai M, Sedgwick J, Tsai M, Galli S. Mast cells enhance T cell activation: Importance of mast cell-derived TNF. Proc Natl Acad Sci U S A. 2005;102:6467-72 pubmed
Mahata B, Pramanik J, van der Weyden L, Polanski K, Kar G, Riedel A, et al. Tumors induce de novo steroid biosynthesis in T cells to evade immunity. Nat Commun. 2020;11:3588 pubmed 出版商
Cao W, Fang F, Gould T, Li X, Kim C, Gustafson C, et al. Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation. J Clin Invest. 2020;130:3422-3436 pubmed 出版商
Tummers B, Mari L, Guy C, Heckmann B, Rodriguez D, Rühl S, et al. Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis. Immunity. 2020;52:994-1006.e8 pubmed 出版商
Han S, Chung D, St Paul M, Liu Z, Garcia Batres C, Elford A, et al. Overproduction of IL-2 by Cbl-b deficient CD4+ T cells provides resistance against regulatory T cells. Oncoimmunology. 2020;9:1737368 pubmed 出版商
Fan X, Wang J, Qin T, Zhang Y, Liu W, Jiang K, et al. Exosome miR-27a-3p secreted from adipocytes targets ICOS to promote antitumor immunity in lung adenocarcinoma. Thorac Cancer. 2020;11:1453-1464 pubmed 出版商
Piao W, Xiong Y, Li L, Saxena V, Smith K, Hippen K, et al. Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration. Cell Rep. 2020;30:1052-1062.e5 pubmed 出版商
Wu R, Liu C, Deng X, Chen L, Hao S, Ma L. Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells. J Cell Mol Med. 2020;24:1684-1699 pubmed 出版商
Gamache A, Cronk J, Nash W, Puchalski P, Gillespie A, Wei H, et al. Ly49R activation receptor drives self-MHC-educated NK cell immunity against cytomegalovirus infection. Proc Natl Acad Sci U S A. 2019;: pubmed 出版商
Cai D, Li J, Liu D, Hong S, Qiao Q, Sun Q, et al. Tumor-expressed B7-H3 mediates the inhibition of antitumor T-cell functions in ovarian cancer insensitive to PD-1 blockade therapy. Cell Mol Immunol. 2019;: pubmed 出版商
Chen L, Strohmeier V, He Z, Deshpande M, Catalan Dibene J, Durum S, et al. Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23. Nat Commun. 2019;10:4517 pubmed 出版商
Nachmani D, Bothmer A, Grisendi S, Mele A, Bothmer D, Lee J, et al. Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita. Nat Genet. 2019;51:1518-1529 pubmed 出版商
Yu T, Gan S, Zhu Q, Dai D, Li N, Wang H, et al. Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24. Nat Commun. 2019;10:4353 pubmed 出版商
Zhang H, Hu Q, Zhang M, Yang F, Peng C, Zhang Z, et al. Bach2 Deficiency Leads to Spontaneous Expansion of IL-4-Producing T Follicular Helper Cells and Autoimmunity. Front Immunol. 2019;10:2050 pubmed 出版商
Selvaraj S, Dhoke N, Kiley J, Mateos Aierdi A, Tungtur S, Mondragón González R, et al. Gene Correction of LGMD2A Patient-Specific iPSCs for the Development of Targeted Autologous Cell Therapy. Mol Ther. 2019;27:2147-2157 pubmed 出版商
Xu J, Pei S, Wang Y, Liu J, Qian Y, Huang M, et al. Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells. Front Immunol. 2019;10:1980 pubmed 出版商
Lionarons D, Hancock D, Rana S, East P, Moore C, Murillo M, et al. RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance. Cancer Cell. 2019;: pubmed 出版商
Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, et al. Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors. Cell. 2019;178:346-360.e24 pubmed 出版商
Khanom U, Ohigashi I, Fujimori S, Kondo K, Takada K, Takahama Y. TCR Affinity for In Vivo Peptide-Induced Thymic Positive Selection Fine-Tunes TCR Responsiveness of Peripheral CD8+ T Cells. J Immunol. 2019;: pubmed 出版商
Zheng M, Li D, Zhao Z, Shytikov D, Xu Q, Jin X, et al. Protein phosphatase 2A has an essential role in promoting thymocyte survival during selection. Proc Natl Acad Sci U S A. 2019;: pubmed 出版商
Zhang Y, Liu R, Cao Q, Fan K, Huang L, Yu J, et al. USP16-mediated deubiquitination of calcineurin A controls peripheral T cell maintenance. J Clin Invest. 2019;129:2856-2871 pubmed 出版商
Persson E, Verstraete K, Heyndrickx I, Gevaert E, Aegerter H, Percier J, et al. Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science. 2019;364: pubmed 出版商
Mizuno R, Sugiura D, Shimizu K, Maruhashi T, Watada M, Okazaki I, et al. PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation. Front Immunol. 2019;10:630 pubmed 出版商
Wagenaar L, van Roest M, Kruijssen L, Simons P, Boon L, Vonk M, et al. Non-digestible oligosaccharides scFOS/lcFOS facilitate safe subcutaneous immunotherapy for peanut allergy. Clin Mol Allergy. 2019;17:7 pubmed 出版商
Anderson C, Reilly E, Lee A, Brossay L. Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection. Cell Rep. 2019;27:537-548.e5 pubmed 出版商
Qian L, Bajana S, Georgescu C, Peng V, Wang H, Adrianto I, et al. Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors. J Exp Med. 2019;216:884-899 pubmed 出版商
Cao Y, Trillo Tinoco J, Sierra R, Anadon C, Dai W, Mohamed E, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nat Commun. 2019;10:1280 pubmed 出版商
Wu J, Chen Y, Dobbs N, Sakai T, Liou J, Miner J, et al. STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death. J Exp Med. 2019;: pubmed 出版商
Paudel S, Baral P, Ghimire L, Bergeron S, Jin L, De Corte J, et al. CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3. Blood. 2019;: pubmed 出版商
Graham K, Werner B, Moyer K, Patton A, Krois C, Yoo H, et al. DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis. Proc Natl Acad Sci U S A. 2019;116:3126-3135 pubmed 出版商
Simonović N, Witalisz Siepracka A, Meissl K, Lassnig C, Reichart U, Kolbe T, et al. NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity. J Immunol. 2019;202:1724-1734 pubmed 出版商
Davies A, Kim H, González Cano R, Choi J, Back S, Roh S, et al. Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury. Cell. 2019;176:716-728.e18 pubmed 出版商
Mikolajczyk T, Nosalski R, Skiba D, Koziol J, Mazur M, Justo Junior A, et al. 1,2,3,4,6-Penta-O-galloyl-β-d-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. Br J Pharmacol. 2019;176:1951-1965 pubmed 出版商
Bern M, Parikh B, Yang L, Beckman D, Poursine Laurent J, Yokoyama W. Inducible down-regulation of MHC class I results in natural killer cell tolerance. J Exp Med. 2019;216:99-116 pubmed 出版商
Lauron E, Yang L, Harvey I, Sojka D, Williams G, Paley M, et al. Viral MHCI inhibition evades tissue-resident memory T cell formation and responses. J Exp Med. 2019;216:117-132 pubmed 出版商
Li J, He Y, Hao J, Ni L, Dong C. High Levels of Eomes Promote Exhaustion of Anti-tumor CD8+ T Cells. Front Immunol. 2018;9:2981 pubmed 出版商
Waldt N, Seifert A, Demiray Y, Devroe E, Turk B, Reichardt P, et al. Filamin A Phosphorylation at Serine 2152 by the Serine/Threonine Kinase Ndr2 Controls TCR-Induced LFA-1 Activation in T Cells. Front Immunol. 2018;9:2852 pubmed 出版商
Bonnefoy F, Gauthier T, Vallion R, Martin Rodriguez O, Missey A, Daoui A, et al. Factors Produced by Macrophages Eliminating Apoptotic Cells Demonstrate Pro-Resolutive Properties and Terminate Ongoing Inflammation. Front Immunol. 2018;9:2586 pubmed 出版商
Chaudhury S, O Connor C, Cañete A, Bittencourt Silvestre J, Sarrou E, Prendergast Á, et al. Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias. Nat Commun. 2018;9:5280 pubmed 出版商
Heinonen T, Ciarlo E, Théroude C, Pelekanou A, Herderschee J, Le Roy D, et al. Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections. Front Immunol. 2018;9:2675 pubmed 出版商
Muscate F, Stetter N, Schramm C, Schulze zur Wiesch J, Bosurgi L, Jacobs T. HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage. Front Immunol. 2018;9:2611 pubmed 出版商
Ushio A, Arakaki R, Otsuka K, Yamada A, Tsunematsu T, Kudo Y, et al. CCL22-Producing Resident Macrophages Enhance T Cell Response in Sjögren's Syndrome. Front Immunol. 2018;9:2594 pubmed 出版商
Zhang W, Li Q, Li D, Li J, Aki D, Liu Y. The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation. J Exp Med. 2018;215:3180-3193 pubmed 出版商
Ng K, Yui M, Mehta A, Siu S, Irwin B, Pease S, et al. A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment. elife. 2018;7: pubmed 出版商
Sandrock I, Reinhardt A, Ravens S, Binz C, Wilharm A, Martins J, et al. Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells. J Exp Med. 2018;215:3006-3018 pubmed 出版商
Grigoryan A, Guidi N, Senger K, Liehr T, Soller K, Marka G, et al. LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells. Genome Biol. 2018;19:189 pubmed 出版商
Lee Sherick A, Jacobsen K, HENRY C, Huey M, Parker R, Page L, et al. MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity. JCI Insight. 2018;3: pubmed 出版商
Lane R, Femel J, Breazeale A, Loo C, Thibault G, Kaempf A, et al. IFNγ-activated dermal lymphatic vessels inhibit cytotoxic T cells in melanoma and inflamed skin. J Exp Med. 2018;215:3057-3074 pubmed 出版商
Bhatt K, Machado H, Osório N, Sousa J, Cardoso F, Magalhães C, et al. A Nonribosomal Peptide Synthase Gene Driving Virulence in Mycobacterium tuberculosis. mSphere. 2018;3: pubmed 出版商
Oike T, Kanagawa H, Sato Y, Kobayashi T, Nakatsukasa H, Miyamoto K, et al. IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse. Sci Rep. 2018;8:15783 pubmed 出版商
Philipp D, Suhr L, Wahlers T, Choi Y, Paunel Görgülü A. Preconditioning of bone marrow-derived mesenchymal stem cells highly strengthens their potential to promote IL-6-dependent M2b polarization. Stem Cell Res Ther. 2018;9:286 pubmed 出版商
Disson O, Blériot C, Jacob J, Serafini N, Dulauroy S, Jouvion G, et al. Peyer's patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion. J Exp Med. 2018;215:2936-2954 pubmed 出版商
Pramanik J, Chen X, Kar G, Henriksson J, Gomes T, Park J, et al. Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation. Genome Med. 2018;10:76 pubmed 出版商
Humblet Baron S, Barber J, Roca C, Lenaerts A, Koni P, Liston A. Murine myeloproliferative disorder as a consequence of impaired collaboration between dendritic cells and CD4 T cells. Blood. 2018;: pubmed 出版商
van Nieuwenhuijze A, Burton O, Lemaitre P, Denton A, Cascalho A, Goodchild R, et al. Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations. Front Immunol. 2018;9:2234 pubmed 出版商
Brajic A, Franckaert D, Burton O, Bornschein S, Calvanese A, Demeyer S, et al. The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells. Front Immunol. 2018;9:1989 pubmed 出版商
Song M, Sandoval T, Chae C, Chopra S, Tan C, Rutkowski M, et al. IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. Nature. 2018;562:423-428 pubmed 出版商
Dong M, Meng Z, Kuerban K, Qi F, Liu J, Wei Y, et al. Diosgenin promotes antitumor immunity and PD-1 antibody efficacy against melanoma by regulating intestinal microbiota. Cell Death Dis. 2018;9:1039 pubmed 出版商
Luu M, Weigand K, Wedi F, Breidenbend C, Leister H, Pautz S, et al. Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate. Sci Rep. 2018;8:14430 pubmed 出版商
Luo H, Winkelmann E, Zhu S, Ru W, Mays E, Silvas J, et al. Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection. J Clin Invest. 2018;128:4980-4991 pubmed 出版商
Min C, Kim H, Ha N, Kim Y, Kwon E, Yen N, et al. A Type I Interferon and IL-10 Induced by Orientia tsutsugamushi Infection Suppresses Antigen-Specific T Cells and Their Memory Responses. Front Immunol. 2018;9:2022 pubmed 出版商
Adam L, Lopez Gonzalez M, Björk A, Pålsson S, Poux C, Wahren Herlenius M, et al. Early Resistance of Non-virulent Mycobacterial Infection in C57BL/6 Mice Is Associated With Rapid Up-Regulation of Antimicrobial Cathelicidin Camp. Front Immunol. 2018;9:1939 pubmed 出版商
Allard D, Wang Y, Li J, Conley B, Xu E, Sailer D, et al. Schwann cell-derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment. J Clin Invest. 2018;128:4727-4741 pubmed 出版商
Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed 出版商
Rodríguez Baena F, Redondo García S, Peris Torres C, Martino Echarri E, Fernández Rodríguez R, Plaza Calonge M, et al. ADAMTS1 protease is required for a balanced immune cell repertoire and tumour inflammatory response. Sci Rep. 2018;8:13103 pubmed 出版商
Kip E, Staal J, Tima H, Verstrepen L, Romano M, Lemeire K, et al. Inhibition of MALT1 Decreases Neuroinflammation and Pathogenicity of Virulent Rabies Virus in Mice. J Virol. 2018;92: pubmed 出版商
Gharagozloo M, Mahmoud S, Simard C, Mahvelati T, Amrani A, Gris D. The Dual Immunoregulatory function of Nlrp12 in T Cell-Mediated Immune Response: Lessons from Experimental Autoimmune Encephalomyelitis. Cells. 2018;7: pubmed 出版商
Napier R, Lee E, Vance E, Snow P, Samson K, Dawson C, et al. Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis. J Immunol. 2018;201:1889-1898 pubmed 出版商
Sequeira I, Neves J, Carrero D, Peng Q, Palasz N, Liakath Ali K, et al. Immunomodulatory role of Keratin 76 in oral and gastric cancer. Nat Commun. 2018;9:3437 pubmed 出版商
Ko Y, Chan Y, Liu C, Liang J, Chuang T, Hsueh Y, et al. Blimp-1-Mediated Pathway Promotes Type I IFN Production in Plasmacytoid Dendritic Cells by Targeting to Interleukin-1 Receptor-Associated Kinase M. Front Immunol. 2018;9:1828 pubmed 出版商
Gibson H, McKnight B, Malysa A, Dyson G, Wiesend W, McCarthy C, et al. IFNγ PET Imaging as a Predictive Tool for Monitoring Response to Tumor Immunotherapy. Cancer Res. 2018;78:5706-5717 pubmed 出版商
McDonald Hyman C, Muller J, Loschi M, Thangavelu G, Saha A, Kumari S, et al. The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease. J Clin Invest. 2018;128:4604-4621 pubmed 出版商
Tartey S, Gurung P, Samir P, Burton A, Kanneganti T. Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses. J Immunol. 2018;201:1639-1644 pubmed 出版商
Stathopoulou C, Gangaplara A, Mallett G, Flomerfelt F, Liniany L, Knight D, et al. PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells. Immunity. 2018;49:247-263.e7 pubmed 出版商
Bending D, Paduraru A, Ducker C, Prieto Martin P, Crompton T, Ono M. A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme. EMBO J. 2018;37: pubmed 出版商
Chen E, Brzostek J, Gascoigne N, Rybakin V. Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation. Sci Rep. 2018;8:10046 pubmed 出版商
Viau A, Bienaime F, Lukas K, Todkar A, Knoll M, Yakulov T, et al. Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. EMBO J. 2018;37: pubmed 出版商
Jensen C, Åhsberg J, Sommarin M, Strid T, Somasundaram R, Okuyama K, et al. Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis. J Exp Med. 2018;215:1947-1963 pubmed 出版商
Kennedy S, Johnson A, Bharrhan S, Lindestam Arlehamn C, Xu J, Garforth S, et al. Identification of Mycobacterial Ribosomal Proteins as Targets for CD4+ T Cells That Enhance Protective Immunity in Tuberculosis. Infect Immun. 2018;86: pubmed 出版商
Alamri A, Rahman R, Zhang M, Alamri A, Gounni A, Kung S. Semaphorin-3E Produced by Immature Dendritic Cells Regulates Activated Natural Killer Cells Migration. Front Immunol. 2018;9:1005 pubmed 出版商
Deshpande N, Uhrlaub J, Way S, Nikolich Zugich J, Kuhns M. A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice. PLoS ONE. 2018;13:e0198354 pubmed 出版商
Wilhelmson A, Lantero Rodriguez M, Svedlund Eriksson E, Johansson I, Fogelstrand P, Stubelius A, et al. Testosterone Protects Against Atherosclerosis in Male Mice by Targeting Thymic Epithelial Cells-Brief Report. Arterioscler Thromb Vasc Biol. 2018;38:1519-1527 pubmed 出版商
Jones R, Cosway E, Willis C, White A, Jenkinson W, Fehling H, et al. Dynamic changes in intrathymic ILC populations during murine neonatal development. Eur J Immunol. 2018;48:1481-1491 pubmed 出版商
Holm T, Tornehave D, Søndergaard H, Kvist P, Sondergaard B, Hansen L, et al. Evaluating IL-21 as a Potential Therapeutic Target in Crohn's Disease. Gastroenterol Res Pract. 2018;2018:5962624 pubmed 出版商
Andargachew R, Martinez R, Kolawole E, Evavold B. CD4 T Cell Affinity Diversity Is Equally Maintained during Acute and Chronic Infection. J Immunol. 2018;201:19-30 pubmed 出版商
Stefani F, Eberstål S, Vergani S, Kristiansen T, Bengzon J. Low-dose irradiated mesenchymal stromal cells break tumor defensive properties in vivo. Int J Cancer. 2018;143:2200-2212 pubmed 出版商
Shi X, Kitano A, Jiang Y, Luu V, Hoegenauer K, Nakada D. Clonal expansion and myeloid leukemia progression modeled by multiplex gene editing of murine hematopoietic progenitor cells. Exp Hematol. 2018;64:33-44.e5 pubmed 出版商
Muri J, Heer S, Matsushita M, Pohlmeier L, Tortola L, Fuhrer T, et al. The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation. Nat Commun. 2018;9:1851 pubmed 出版商
Pittala S, Krelin Y, Shoshan Barmatz V. Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide. Neoplasia. 2018;20:594-609 pubmed 出版商
Schmolka N, Papotto P, Romero P, Amado T, Enguita F, Amorim A, et al. MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1. Sci Immunol. 2018;3: pubmed 出版商
Qian P, De Kumar B, He X, Nolte C, Gogol M, Ahn Y, et al. Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis. Cell Stem Cell. 2018;22:740-754.e7 pubmed 出版商
Wunderlich C, Ackermann P, Ostermann A, Adams Quack P, Vogt M, Tran M, et al. Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment. Nat Commun. 2018;9:1646 pubmed 出版商
Theisen E, McDougal C, Nakanishi M, Stevenson D, Amador Noguez D, Rosenberg D, et al. Cyclooxygenase-1 and -2 Play Contrasting Roles in Listeria-Stimulated Immunity. J Immunol. 2018;200:3729-3738 pubmed 出版商
Silva M, Davoli Ferreira M, Medina T, Sesti Costa R, Silva G, Lopes C, et al. Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis. Nat Commun. 2018;9:1513 pubmed 出版商
Youssef L, Rebbaa A, Pampou S, Weisberg S, Stockwell B, Hod E, et al. Increased erythrophagocytosis induces ferroptosis in red pulp macrophages in a mouse model of transfusion. Blood. 2018;: pubmed 出版商
Zhang J, He Z, Sen S, Wang F, Zhang Q, Sun Z. TCF-1 Inhibits IL-17 Gene Expression To Restrain Th17 Immunity in a Stage-Specific Manner. J Immunol. 2018;200:3397-3406 pubmed 出版商
Xia P, Wang S, Ye B, Du Y, Li C, Xiong Z, et al. A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion. Immunity. 2018;48:688-701.e7 pubmed 出版商
Lee J, Kim J, Yi J, Kim D, Kim H, Han D, et al. Phenotypic and Functional Changes of Peripheral Ly6C+ T Regulatory Cells Driven by Conventional Effector T Cells. Front Immunol. 2018;9:437 pubmed 出版商
Swafford D, Shanmugam A, Ranganathan P, Hussein M, Koni P, Prasad P, et al. Canonical Wnt Signaling in CD11c+ APCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon. J Immunol. 2018;200:3259-3268 pubmed 出版商
Tong H, Miyake Y, Mi ichi F, Iwakura Y, Hara H, Yoshida H. Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells. PLoS ONE. 2018;13:e0195119 pubmed 出版商
Kiyota T, Machhi J, Lu Y, Dyavarshetty B, Nemati M, Yokoyama I, et al. Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer's disease mice. J Neuroimmunol. 2018;319:80-92 pubmed 出版商
Moreno Fernandez M, Giles D, Stankiewicz T, Sheridan R, Karns R, Cappelletti M, et al. Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease. JCI Insight. 2018;3: pubmed 出版商
Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine T, et al. Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression. J Clin Invest. 2018;128:2487-2499 pubmed 出版商
Xi J, Huang Q, Wang L, Ma X, Deng Q, Kumar M, et al. miR-21 depletion in macrophages promotes tumoricidal polarization and enhances PD-1 immunotherapy. Oncogene. 2018;37:3151-3165 pubmed 出版商
Mair I, Zandee S, Toor I, Saul L, McPherson R, Leech M, et al. A Context-Dependent Role for αv Integrins in Regulatory T Cell Accumulation at Sites of Inflammation. Front Immunol. 2018;9:264 pubmed 出版商
Fransen M, Benonisson H, van Maren W, Sow H, Breukel C, Linssen M, et al. A Restricted Role for FcγR in the Regulation of Adaptive Immunity. J Immunol. 2018;200:2615-2626 pubmed 出版商
Jung J, Eggleton P, Robinson A, Wang J, Gutowski N, Holley J, et al. Calnexin is necessary for T cell transmigration into the central nervous system. JCI Insight. 2018;3: pubmed 出版商
Blass E, Aid M, Martinot A, Larocca R, Kang Z, Badamchi Zadeh A, et al. Adenovirus Vector Vaccination Impacts NK Cell Rheostat Function following Lymphocytic Choriomeningitis Virus Infection. J Virol. 2018;92: pubmed 出版商
Xu Y, Ikeda S, Sumida K, Yamamoto R, Tanaka H, Minato N. Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells. Nat Commun. 2018;9:914 pubmed 出版商
Mayordomo A, Silva J, Gorlino C, Arias J, Berón W, Di Genaro M. IL-12/23p40 overproduction by dendritic cells leads to an increased Th1 and Th17 polarization in a model of Yersinia enterocolitica-induced reactive arthritis in TNFRp55-/- mice. PLoS ONE. 2018;13:e0193573 pubmed 出版商
Muir L, Kiridena S, Griffin C, Delproposto J, Geletka L, Martinez Santibañez G, et al. Frontline Science: Rapid adipose tissue expansion triggers unique proliferation and lipid accumulation profiles in adipose tissue macrophages. J Leukoc Biol. 2018;103:615-628 pubmed 出版商
Gomes R, Silva M, Dos Santos J, van Linge C, Reis J, Teixeira M, et al. Human Interleukin-32γ Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice. Infect Immun. 2018;86: pubmed 出版商
Sengar P, Juarez P, Verdugo Meza A, Arellano D, Jain A, Chauhan K, et al. Development of a functionalized UV-emitting nanocomposite for the treatment of cancer using indirect photodynamic therapy. J Nanobiotechnology. 2018;16:19 pubmed 出版商
Flores Santibáñez F, Cuadra B, Fernandez D, Rosemblatt M, Nuñez S, Cruz P, et al. In Vitro-Generated Tc17 Cells Present a Memory Phenotype and Serve As a Reservoir of Tc1 Cells In Vivo. Front Immunol. 2018;9:209 pubmed 出版商
Yang J, Cornelissen F, Papazian N, Reijmers R, Llorian M, Cupedo T, et al. IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes. J Exp Med. 2018;215:1069-1077 pubmed 出版商
Bhaskaran N, Liu Z, Saravanamuthu S, Yan C, Hu Y, Dong L, et al. Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity. Front Immunol. 2018;9:184 pubmed 出版商
Yu J, Duong V, Westphal K, Westphal A, Suwandi A, Grassl G, et al. Surface receptor Toso controls B cell-mediated regulation of T cell immunity. J Clin Invest. 2018;128:1820-1836 pubmed 出版商
Akuffo A, Alontaga A, Metcalf R, Beatty M, Becker A, McDaniel J, et al. Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon. J Biol Chem. 2018;293:6187-6200 pubmed 出版商
Beesetty P, Wieczerzak K, Gibson J, Kaitsuka T, Luu C, Matsushita M, et al. Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry. Sci Rep. 2018;8:3023 pubmed 出版商
Lauron E, Yang L, Elliott J, Gainey M, Fremont D, Yokoyama W. Cross-priming induces immunodomination in the presence of viral MHC class I inhibition. PLoS Pathog. 2018;14:e1006883 pubmed 出版商
Supramaniam A, Liu X, Ferro V, Herrero L. Prophylactic Antiheparanase Activity by PG545 Is Antiviral In Vitro and Protects against Ross River Virus Disease in Mice. Antimicrob Agents Chemother. 2018;62: pubmed 出版商
Liang W, Mao S, Sun S, Li M, Li Z, Yu R, et al. Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation. Front Immunol. 2018;9:78 pubmed 出版商
Zhao M, Tan Y, Peng Q, Huang C, Guo Y, Liang G, et al. IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic regulation. Nat Commun. 2018;9:583 pubmed 出版商
Cortes J, Ambesi Impiombato A, Couronné L, Quinn S, Kim C, da Silva Almeida A, et al. RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis. Cancer Cell. 2018;33:259-273.e7 pubmed 出版商
Ranganathan P, Shanmugam A, Swafford D, Suryawanshi A, Bhattacharjee P, Hussein M, et al. GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis. J Immunol. 2018;200:1781-1789 pubmed 出版商
Kip E, Staal J, Verstrepen L, Tima H, Terryn S, Romano M, et al. MALT1 Controls Attenuated Rabies Virus by Inducing Early Inflammation and T Cell Activation in the Brain. J Virol. 2018;92: pubmed 出版商
SMITH C, Allard D, Wang Y, Howard J, Montgomery S, Su M. IL-10 Paradoxically Promotes Autoimmune Neuropathy through S1PR1-Dependent CD4+ T Cell Migration. J Immunol. 2018;200:1580-1592 pubmed 出版商
Solanki A, Yanez D, Ross S, Lau C, Papaioannou E, Li J, et al. Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh. Development. 2018;145: pubmed 出版商
Varanasi S, Jaggi U, Hay N, Rouse B. Hexokinase II may be dispensable for CD4 T cell responses against a virus infection. PLoS ONE. 2018;13:e0191533 pubmed 出版商
Tenno M, Kojo S, Lawir D, Hess I, Shiroguchi K, Ebihara T, et al. Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors. J Exp Med. 2018;215:595-610 pubmed 出版商
Ferdinand J, Richard A, Meylan F, Al Shamkhani A, Siegel R. Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells. J Immunol. 2018;200:1360-1369 pubmed 出版商
Goldman N, Lomakova Y, Londregan J, Bucknum A, DePierri K, Somerville J, et al. High macrophage PD-L1 expression not responsible for T cell suppression. Cell Immunol. 2018;324:50-58 pubmed 出版商
Cowan J, Baik S, McCarthy N, Parnell S, White A, Jenkinson W, et al. Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus. Eur J Immunol. 2018;48:844-854 pubmed 出版商
Delpoux A, Michelini R, Verma S, Lai C, Omilusik K, Utzschneider D, et al. Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells. J Exp Med. 2018;215:575-594 pubmed 出版商
Chang C, Goods B, Askenase M, Hammond M, Renfroe S, Steinschneider A, et al. Erythrocyte efferocytosis modulates macrophages towards recovery after intracerebral hemorrhage. J Clin Invest. 2018;128:607-624 pubmed 出版商
Shi B, Geng J, Wang Y, Wei H, Walters B, Li W, et al. Foxp1 Negatively Regulates T Follicular Helper Cell Differentiation and Germinal Center Responses by Controlling Cell Migration and CTLA-4. J Immunol. 2018;200:586-594 pubmed 出版商
Villadiego J, Labrador Garrido A, Franco J, Leal Lasarte M, De Genst E, Dobson C, et al. Immunization with ?-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model. Glia. 2018;66:191-205 pubmed 出版商
Zimmermann J, Durek P, Kuhl A, Schattenberg F, Maschmeyer P, Siracusa F, et al. The intestinal microbiota determines the colitis-inducing potential of T-bet-deficient Th cells in mice. Eur J Immunol. 2018;48:161-167 pubmed 出版商
Robb C, McSorley H, Lee J, Aoki T, Yu C, Crittenden S, et al. Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis. J Allergy Clin Immunol. 2018;141:152-162 pubmed 出版商
Dutton E, Camelo A, Sleeman M, Herbst R, Carlesso G, Belz G, et al. Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity. Wellcome Open Res. 2017;2:117 pubmed 出版商
Liang D, Tian L, You R, Halpert M, Konduri V, Baig Y, et al. AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity. Front Immunol. 2017;8:1801 pubmed 出版商
Field C, Hunn M, Ferguson P, Ruedl C, Ancelet L, Hermans I. Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model. Oncoimmunology. 2017;7:e1376154 pubmed 出版商
Lam J, Chua Y, Lee P, Martínez Gómez J, Ooi E, Alonso S. Dengue vaccine-induced CD8+ T cell immunity confers protection in the context of enhancing, interfering maternal antibodies. JCI Insight. 2017;2: pubmed 出版商
Rapp A, Hachemi Y, Kemmler J, Koenen M, Tuckermann J, Ignatius A. Induced global deletion of glucocorticoid receptor impairs fracture healing. FASEB J. 2017;: pubmed 出版商
Milner J, Toma C, Yu B, Zhang K, Omilusik K, Phan A, et al. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. 2017;552:253-257 pubmed 出版商
Seehus C, Kadavallore A, Torre B, Yeckes A, Wang Y, Tang J, et al. Alternative activation generates IL-10 producing type 2 innate lymphoid cells. Nat Commun. 2017;8:1900 pubmed 出版商
Pollok K, Mothes R, Ulbricht C, Liebheit A, Gerken J, Uhlmann S, et al. The chronically inflamed central nervous system provides niches for long-lived plasma cells. Acta Neuropathol Commun. 2017;5:88 pubmed 出版商
Ellen B, Maya I, Tania M, Jessica V, Nele B, Louis B, et al. Lymphocyte-independent pathways underlie the pathogenesis of murine cytomegalovirus-associated secondary hemophagocytic lymphohistiocytosis. Clin Exp Immunol. 2017;: pubmed 出版商
Grau K, Roth A, Zhu S, Hernández A, Colliou N, DiVita B, et al. The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue. Nat Microbiol. 2017;2:1586-1591 pubmed 出版商
Morillon Y, Hammond S, Durham N, Schlom J, Greiner J. Enhanced immunotherapy by combining a vaccine with a novel murine GITR ligand fusion protein. Oncotarget. 2017;8:73469-73482 pubmed 出版商
Jones G, Smith V, D Orazio S. Listeria monocytogenes Replicate in Bone Marrow-Derived CD11c+ Cells but Not in Dendritic Cells Isolated from the Murine Gastrointestinal Tract. J Immunol. 2017;199:3789-3797 pubmed 出版商
O Neill R, Du W, Mohammadpour H, Alqassim E, Qiu J, Chen G, et al. T Cell-Derived CD70 Delivers an Immune Checkpoint Function in Inflammatory T Cell Responses. J Immunol. 2017;199:3700-3710 pubmed 出版商
Deng R, Hurtz C, Song Q, Yue C, Xiao G, Yu H, et al. Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease. Nat Commun. 2017;8:978 pubmed 出版商
Wang J, He N, Zhang N, Quan D, Zhang S, Zhang C, et al. NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection. Nat Commun. 2017;8:959 pubmed 出版商
Basler M, Maurits E, de Bruin G, Koerner J, Overkleeft H, Groettrup M. Amelioration of autoimmunity with an inhibitor selectively targeting all active centers of the immunoproteasome. Br J Pharmacol. 2017;: pubmed 出版商
Vonk M, Wagenaar L, Pieters R, Knippels L, Willemsen L, Smit J, et al. The efficacy of oral and subcutaneous antigen-specific immunotherapy in murine cow's milk- and peanut allergy models. Clin Transl Allergy. 2017;7:35 pubmed 出版商
Kim H, Jang S, Lee W, Kim K, Sohn H, Hwang S, et al. PTEN drives Th17 cell differentiation by preventing IL-2 production. J Exp Med. 2017;214:3381-3398 pubmed 出版商
Chu F, Hu Y, Zhou Y, Guo M, Lu J, Zheng W, et al. MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway. Clin Exp Immunol. 2017;: pubmed 出版商
Bern M, Beckman D, Ebihara T, Taffner S, Poursine Laurent J, White J, et al. Immunoreceptor tyrosine-based inhibitory motif-dependent functions of an MHC class I-specific NK cell receptor. Proc Natl Acad Sci U S A. 2017;114:E8440-E8447 pubmed 出版商
Ebina Shibuya R, Matsumoto M, Kuwahara M, Jang K, Sugai M, Ito Y, et al. Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis. J Biol Chem. 2017;292:18098-18112 pubmed 出版商
Koyanagi N, Imai T, Shindo K, Sato A, Fujii W, Ichinohe T, et al. Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis. J Clin Invest. 2017;127:3784-3795 pubmed 出版商
Chávez Galán L, Vesin D, Uysal H, Blaser G, Benkhoucha M, Ryffel B, et al. Transmembrane Tumor Necrosis Factor Controls Myeloid-Derived Suppressor Cell Activity via TNF Receptor 2 and Protects from Excessive Inflammation during BCG-Induced Pleurisy. Front Immunol. 2017;8:999 pubmed 出版商
Kollek M, Voigt G, Molnar C, Murad F, Bertele D, Krombholz C, et al. Transient apoptosis inhibition in donor stem cells improves hematopoietic stem cell transplantation. J Exp Med. 2017;214:2967-2983 pubmed 出版商
Gulen M, Koch U, Haag S, Schüler F, Apetoh L, Villunger A, et al. Signalling strength determines proapoptotic functions of STING. Nat Commun. 2017;8:427 pubmed 出版商
Kurachi M, Kurachi J, Chen Z, Johnson J, Khan O, Bengsch B, et al. Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function. Nat Protoc. 2017;12:1980-1998 pubmed 出版商
Zaid A, Hor J, Christo S, Groom J, Heath W, Mackay L, et al. Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation. J Immunol. 2017;199:2451-2459 pubmed 出版商
Jang E, Lee H, Lee G, Oh A, Cha J, Igarashi K, et al. Bach2 represses the AP-1-driven induction of interleukin-2 gene transcription in CD4+ T cells. BMB Rep. 2017;50:472-477 pubmed
He Z, Ma J, Wang R, Zhang J, Huang Z, Wang F, et al. A two-amino-acid substitution in the transcription factor RORγt disrupts its function in TH17 differentiation but not in thymocyte development. Nat Immunol. 2017;18:1128-1138 pubmed 出版商
Kim D, Dastidar H, Zhang C, Zemp F, Lau K, Ernst M, et al. Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms. Nat Commun. 2017;8:344 pubmed 出版商
Tenno M, Shiroguchi K, Muroi S, Kawakami E, Koseki K, Kryukov K, et al. Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling. J Exp Med. 2017;214:2933-2946 pubmed 出版商
Li L, Labuda J, Imai D, Griffey S, McSorley S. CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract. J Immunol. 2017;199:2547-2554 pubmed 出版商
Varanasi S, Donohoe D, Jaggi U, Rouse B. Manipulating Glucose Metabolism during Different Stages of Viral Pathogenesis Can Have either Detrimental or Beneficial Effects. J Immunol. 2017;199:1748-1761 pubmed 出版商
Acuff N, Li X, Latha K, Nagy T, Watford W. Tpl2 Promotes Innate Cell Recruitment and Effector T Cell Differentiation To Limit Citrobacter rodentium Burden and Dissemination. Infect Immun. 2017;85: pubmed 出版商
Weis V, Königsberger S, Amler S, Wienands J, Kiefer F. Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation. Mol Cell Biol. 2017;37: pubmed 出版商
Llewellyn R, Thomas K, Gutknecht M, Bouton A. The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state. J Leukoc Biol. 2017;102:1069-1080 pubmed 出版商
Liao X, Ren J, Reihl A, Pirapakaran T, Sreekumar B, Cecere T, et al. Renal-infiltrating CD11c+ cells are pathogenic in murine lupus nephritis through promoting CD4+ T cell responses. Clin Exp Immunol. 2017;190:187-200 pubmed 出版商
Novince C, Whittow C, Aartun J, Hathaway J, Poulides N, Chavez M, et al. Commensal Gut Microbiota Immunomodulatory Actions in Bone Marrow and Liver have Catabolic Effects on Skeletal Homeostasis in Health. Sci Rep. 2017;7:5747 pubmed 出版商
He Z, Chen L, Souto F, Canasto Chibuque C, Bongers G, Deshpande M, et al. Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc Min/+ mice. Sci Rep. 2017;7:5520 pubmed 出版商
Van Den Ham K, Smith L, Richer M, Olivier M. Protein Tyrosine Phosphatase Inhibition Prevents Experimental Cerebral Malaria by Precluding CXCR3 Expression on T Cells. Sci Rep. 2017;7:5478 pubmed 出版商
Bhela S, Varanasi S, Jaggi U, Sloan S, Rajasagi N, Rouse B. The Plasticity and Stability of Regulatory T Cells during Viral-Induced Inflammatory Lesions. J Immunol. 2017;199:1342-1352 pubmed 出版商
Blackmore S, Hernandez J, Juda M, Ryder E, Freund G, Johnson R, et al. Influenza infection triggers disease in a genetic model of experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A. 2017;114:E6107-E6116 pubmed 出版商
Nadya N, Tezuka H, Ohteki T, Matsuda S, Azuma M, Nagai S. PI3K-Akt pathway enhances the differentiation of interleukin-27-induced type 1 regulatory T cells. Immunology. 2017;152:507-516 pubmed 出版商
Belgiovine C, Bello E, Liguori M, Craparotta I, Mannarino L, Paracchini L, et al. Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models. Br J Cancer. 2017;117:628-638 pubmed 出版商
He Z, Wang F, Zhang J, Sen S, Pang Q, Luo S, et al. Regulation of Th17 Differentiation by IKK?-Dependent and -Independent Phosphorylation of ROR?t. J Immunol. 2017;199:955-964 pubmed 出版商
Miletić A, Lenartic M, Popovic B, Brizic I, Trsan T, Miklic K, et al. NCR1-deficiency diminishes the generation of protective murine cytomegalovirus antibodies by limiting follicular helper T-cell maturation. Eur J Immunol. 2017;47:1443-1456 pubmed 出版商
Lupfer C, Stokes K, Kuriakose T, Kanneganti T. Deficiency of the NOD-Like Receptor NLRC5 Results in Decreased CD8+ T Cell Function and Impaired Viral Clearance. J Virol. 2017;91: pubmed 出版商
Mattila J, Beaino W, Maiello P, Coleman M, White A, Scanga C, et al. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin ?4?1-Expressing Immune Cells. J Immunol. 2017;199:806-815 pubmed 出版商
Becattini S, Littmann E, Carter R, Kim S, Morjaria S, Ling L, et al. Commensal microbes provide first line defense against Listeria monocytogenes infection. J Exp Med. 2017;214:1973-1989 pubmed 出版商
Bergmann H, Roth S, Pechloff K, Kiss E, Kuhn S, Heikenwalder M, et al. Card9-dependent IL-1? regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer. Eur J Immunol. 2017;47:1342-1353 pubmed 出版商
Moreira Teixeira L, Redford P, Stavropoulos E, Ghilardi N, Maynard C, Weaver C, et al. T Cell-Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection. J Immunol. 2017;199:613-623 pubmed 出版商
Chae W, Park J, Henegariu O, Yilmaz S, Hao L, Bothwell A. Membrane-bound Dickkopf-1 in Foxp3+ regulatory T cells suppresses T-cell-mediated autoimmune colitis. Immunology. 2017;152:265-275 pubmed 出版商
Leigh N, O Neill R, Du W, Chen C, Qiu J, Ashwell J, et al. Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function. J Immunol. 2017;199:336-347 pubmed 出版商
Vaitaitis G, Waid D, Yussman M, Wagner D. CD40-mediated signalling influences trafficking, T-cell receptor expression, and T-cell pathogenesis, in the NOD model of type 1 diabetes. Immunology. 2017;152:243-254 pubmed 出版商
Mendoza A, Fang V, Chen C, Serasinghe M, Verma A, Muller J, et al. Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. Nature. 2017;546:158-161 pubmed 出版商
Oh D, Kim H, Oh J, Jung H, Lee Y, Park J, et al. Intratumoral depletion of regulatory T cells using CD25-targeted photodynamic therapy in a mouse melanoma model induces antitumoral immune responses. Oncotarget. 2017;8:47440-47453 pubmed 出版商
Miao T, Symonds A, Singh R, Symonds J, Ogbe A, Omodho B, et al. Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017;214:1787-1808 pubmed 出版商
Govender L, Wyss J, Kumar R, Pascual M, Golshayan D. IL-2-Mediated In Vivo Expansion of Regulatory T Cells Combined with CD154-CD40 Co-Stimulation Blockade but Not CTLA-4 Ig Prolongs Allograft Survival in Naive and Sensitized Mice. Front Immunol. 2017;8:421 pubmed 出版商
Rialdi A, Hultquist J, Jimenez Morales D, Peralta Z, Campisi L, Fenouil R, et al. The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity. Cell. 2017;169:679-692.e14 pubmed 出版商
Olson M, Ulrich B, Hummel S, Khan I, Meuris B, Cherukuri Y, et al. Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production. J Immunol. 2017;198:4352-4359 pubmed 出版商
Henriquez C, Morán G, Carrasco C, Sarmiento J, Barria M, Folch H, et al. Modulatory role of regulatory T cells in a murine model of severe equine asthma. BMC Vet Res. 2017;13:117 pubmed 出版商
Meinicke H, Bremser A, Brack M, Schrenk K, Pircher H, Izcue A. KLRG1 impairs regulatory T-cell competitive fitness in the gut. Immunology. 2017;152:65-73 pubmed 出版商
Meinicke H, Bremser A, Brack M, Akeus P, Pearson C, Bullers S, et al. Tumour-associated changes in intestinal epithelial cells cause local accumulation of KLRG1+ GATA3+ regulatory T cells in mice. Immunology. 2017;152:74-88 pubmed 出版商
Maceiras A, Almeida S, Mariotti Ferrandiz E, Chaara W, Jebbawi F, Six A, et al. T follicular helper and T follicular regulatory cells have different TCR specificity. Nat Commun. 2017;8:15067 pubmed 出版商
Li Y, Liu X, Duan W, Tian H, Zhu G, He H, et al. Batf3-dependent CD8?+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages. EBioMedicine. 2017;18:188-198 pubmed 出版商
Zhu F, Willette Brown J, Song N, Lomada D, Song Y, Xue L, et al. Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis. Cell Host Microbe. 2017;21:478-493.e7 pubmed 出版商
Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, et al. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med. 2017;214:1453-1469 pubmed 出版商
Lagumersindez Denis N, Wrzos C, Mack M, Winkler A, van der Meer F, Reinert M, et al. Differential contribution of immune effector mechanisms to cortical demyelination in multiple sclerosis. Acta Neuropathol. 2017;134:15-34 pubmed 出版商
Chapman L, Ture S, Field D, Morrell C. miR-451 limits CD4+ T cell proliferative responses to infection in mice. Immunol Res. 2017;65:828-840 pubmed 出版商
Zhu H, Lou F, Yin Q, Gao Y, Sun Y, Bai J, et al. RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease. EMBO Mol Med. 2017;9:589-604 pubmed 出版商
Bruce D, Stefanski H, Vincent B, Dant T, Reisdorf S, Bommiasamy H, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. J Clin Invest. 2017;127:1813-1825 pubmed 出版商
Davis R, Moore E, Clavijo P, Friedman J, Cash H, Chen Z, et al. Anti-PD-L1 Efficacy Can Be Enhanced by Inhibition of Myeloid-Derived Suppressor Cells with a Selective Inhibitor of PI3K?/?. Cancer Res. 2017;77:2607-2619 pubmed 出版商
Powell D, Frelinger J. Efficacy of Resistance to Francisella Imparted by ITY/NRAMP/SLC11A1 Depends on Route of Infection. Front Immunol. 2017;8:206 pubmed 出版商
Vazquez Mateo C, Collins J, Fleury M, Dooms H. Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7R? antibodies in NOD mice. BMC Immunol. 2017;18:18 pubmed 出版商
Nouri Shirazi M, Bible B, Zeng M, Tamjidi S, Bossart G. Phenotyping and comparing the immune cell populations of free-ranging Atlantic bottlenose dolphins (Tursiops truncatus) and dolphins under human care. BMC Vet Res. 2017;13:78 pubmed 出版商
Sun X, Li C, Liu Y, Du L, Zeng M, Zheng X, et al. T-Cell Mineralocorticoid Receptor Controls Blood Pressure by Regulating Interferon-Gamma. Circ Res. 2017;120:1584-1597 pubmed 出版商
Dombrowski Y, O Hagan T, Dittmer M, Penalva R, Mayoral S, Bankhead P, et al. Regulatory T cells promote myelin regeneration in the central nervous system. Nat Neurosci. 2017;20:674-680 pubmed 出版商
Ho C, Chhabra A, Starkl P, Schnorr P, Wilmes S, Moraga I, et al. Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling. Cell. 2017;168:1041-1052.e18 pubmed 出版商
Goldman N, Valiuskyte K, Londregan J, Swider A, Somerville J, Riggs J. Macrophage regulation of B cell proliferation. Cell Immunol. 2017;314:54-62 pubmed 出版商
Jones G, D Orazio S. Monocytes Are the Predominant Cell Type Associated with Listeria monocytogenes in the Gut, but They Do Not Serve as an Intracellular Growth Niche. J Immunol. 2017;198:2796-2804 pubmed 出版商
Martinic M, Caminschi I, O Keeffe M, Thinnes T, Grumont R, Gerondakis S, et al. The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+ Thymocyte Selection. J Immunol. 2017;198:2649-2660 pubmed 出版商
Zamarin D, Holmgaard R, Ricca J, Plitt T, Palese P, Sharma P, et al. Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity. Nat Commun. 2017;8:14340 pubmed 出版商
Schiering C, Wincent E, Metidji A, Iseppon A, Li Y, Potocnik A, et al. Feedback control of AHR signalling regulates intestinal immunity. Nature. 2017;542:242-245 pubmed 出版商
Kim H, Kwon K, Kim W, Shin S. Virulence-dependent induction of interleukin-10-producing-tolerogenic dendritic cells by Mycobacterium tuberculosis impedes optimal T helper type 1 proliferation. Immunology. 2017;151:177-190 pubmed 出版商
Oh J, Oh D, Jung H, Lee H. A mechanism for the induction of type 2 immune responses by a protease allergen in the genital tract. Proc Natl Acad Sci U S A. 2017;114:E1188-E1195 pubmed 出版商
Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed 出版商
Chucair Elliott A, Carr M, Carr D. Long-term consequences of topical dexamethasone treatment during acute corneal HSV-1 infection on the immune system. J Leukoc Biol. 2017;101:1253-1261 pubmed 出版商
Britton G, Ambler R, Clark D, Hill E, Tunbridge H, McNally K, et al. PKC? links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton. elife. 2017;6: pubmed 出版商
Zamarron B, Mergian T, Cho K, Martinez Santibañez G, Luan D, Singer K, et al. Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice. Diabetes. 2017;66:392-406 pubmed 出版商
Varanasi S, Reddy P, Bhela S, Jaggi U, Giménez F, Rouse B. Azacytidine Treatment Inhibits the Progression of Herpes Stromal Keratitis by Enhancing Regulatory T Cell Function. J Virol. 2017;91: pubmed 出版商
Qu J, Do D, Zhou Y, Luczak E, Mitzner W, Anderson M, et al. Oxidized CaMKII promotes asthma through the activation of mast cells. JCI Insight. 2017;2:e90139 pubmed 出版商
Bracamonte Baran W, Florentin J, Zhou Y, Jankowska Gan E, Haynes W, Zhong W, et al. Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance. Proc Natl Acad Sci U S A. 2017;114:1099-1104 pubmed 出版商
Blanquiceth Y, Rodríguez Perea A, Tabares Guevara J, Correa L, Sánchez M, Ramirez Pineda J, et al. Increase of Frequency and Modulation of Phenotype of Regulatory T Cells by Atorvastatin Is Associated with Decreased Lung Inflammatory Cell Infiltration in a Murine Model of Acute Allergic Asthma. Front Immunol. 2016;7:620 pubmed 出版商
Araujo L, Khim P, Mkhikian H, Mortales C, Demetriou M. Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation. elife. 2017;6: pubmed 出版商
Atkin Smith G, Paone S, Zanker D, Duan M, Phan T, Chen W, et al. Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting. Sci Rep. 2017;7:39846 pubmed 出版商
Ehrlich A, Fernández O, Rodriguez Pinto D, Castilho T, Corral Caridad M, Goldsmith Pestana K, et al. Local Delivery of the Toll-Like Receptor 9 Ligand CpG Downregulates Host Immune and Inflammatory Responses, Ameliorating Established Leishmania (Viannia) panamensis Chronic Infection. Infect Immun. 2017;85: pubmed 出版商
Chen S, Cai C, Li Z, Liu G, Wang Y, Blonska M, et al. Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity. J Exp Med. 2017;214:475-489 pubmed 出版商
Kuhn C, Rezende R, M Hamdi H, da Cunha A, Weiner H. IL-6 Inhibits Upregulation of Membrane-Bound TGF-? 1 on CD4+ T Cells and Blocking IL-6 Enhances Oral Tolerance. J Immunol. 2017;198:1202-1209 pubmed 出版商
Lee P, Zhu Z, Hachmann J, Nojima T, Kitamura D, Salvesen G, et al. Differing Requirements for MALT1 Function in Peripheral B Cell Survival and Differentiation. J Immunol. 2017;198:1066-1080 pubmed 出版商
Xu X, Han L, Zhao G, Xue S, Gao Y, Xiao J, et al. LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis. J Exp Med. 2017;214:209-226 pubmed 出版商
Hayakawa M, Hayakawa H, Petrova T, Ritprajak P, Sutavani R, Jiménez Andrade G, et al. Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction. J Biol Chem. 2017;292:1762-1772 pubmed 出版商
Li M, Li Z, Yao Y, Jin W, Wood K, Liu Q, et al. Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity. Proc Natl Acad Sci U S A. 2017;114:E396-E405 pubmed 出版商
Nair V, Song M, Ko M, Oh K. DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA Methyltransferases. Mol Cells. 2016;39:888-897 pubmed 出版商
Karki R, Man S, Malireddi R, Kesavardhana S, Zhu Q, Burton A, et al. NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer. Nature. 2016;540:583-587 pubmed 出版商
Kuchmiy A, D Hont J, Hochepied T, Lamkanfi M. NLRP2 controls age-associated maternal fertility. J Exp Med. 2016;213:2851-2860 pubmed
Meng C, Li Z, Fang W, Song Z, Yang D, Li D, et al. Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy. J Cell Mol Med. 2017;21:697-710 pubmed 出版商
Davis R, Silvin C, Allen C. Avoiding phagocytosis-related artifact in myeloid derived suppressor cell T-lymphocyte suppression assays. J Immunol Methods. 2017;440:12-18 pubmed 出版商
Müller A, Florek M, Kohrt H, Küpper N, Filatenkov A, Linderman J, et al. Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning. J Immunol. 2016;197:4151-4162 pubmed
Gomes R, Cavalcanti K, Teixeira C, Carvalho A, Mattos P, Cristal J, et al. Immunity to Lutzomyia whitmani Saliva Protects against Experimental Leishmania braziliensis Infection. PLoS Negl Trop Dis. 2016;10:e0005078 pubmed 出版商
Carroll V, Lafferty M, Marchionni L, Bryant J, Gallo R, Garzino Demo A. Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice. Proc Natl Acad Sci U S A. 2016;113:13168-13173 pubmed
Zhou Y, Weng X, Dou R, Tan X, Zhang T, Fang J, et al. Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice. Acta Pharmacol Sin. 2017;38:201-210 pubmed 出版商
Chen Q, Xu L, Liang C, Wang C, Peng R, Liu Z. Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy. Nat Commun. 2016;7:13193 pubmed 出版商
Massaad M, Zhou J, Tsuchimoto D, Chou J, Jabara H, Janssen E, et al. Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. J Clin Invest. 2016;126:4219-4236 pubmed 出版商
Case A, Roessner C, Tian J, Zimmerman M. Mitochondrial Superoxide Signaling Contributes to Norepinephrine-Mediated T-Lymphocyte Cytokine Profiles. PLoS ONE. 2016;11:e0164609 pubmed 出版商
Chudnovskiy A, Mortha A, Kana V, Kennard A, Ramírez J, Rahman A, et al. Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. Cell. 2016;167:444-456.e14 pubmed 出版商
Sato Y, Mii A, Hamazaki Y, Fujita H, Nakata H, Masuda K, et al. Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney. JCI Insight. 2016;1:e87680 pubmed 出版商
Eil R, Vodnala S, Clever D, Klebanoff C, Sukumar M, Pan J, et al. Ionic immune suppression within the tumour microenvironment limits T cell effector function. Nature. 2016;537:539-543 pubmed 出版商
Oudhoff M, Antignano F, Chenery A, Burrows K, Redpath S, Braam M, et al. Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection. PLoS Pathog. 2016;12:e1005876 pubmed 出版商
Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed 出版商
Yoon J, Leyva Castillo J, Wang G, Galand C, Oyoshi M, Kumar L, et al. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016;213:2147-66 pubmed 出版商
Kim K, Williams J, Wang Y, Ivanov S, Gilfillan S, Colonna M, et al. MHC II+ resident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytes. J Exp Med. 2016;213:1951-9 pubmed 出版商
Henry E, Sy C, Inclan Rico J, Espinosa V, Ghanny S, Dwyer D, et al. Carbonic anhydrase enzymes regulate mast cell-mediated inflammation. J Exp Med. 2016;213:1663-73 pubmed 出版商
Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, et al. Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion. J Exp Med. 2016;213:1881-900 pubmed 出版商
Lenac Rovis T, Kucan Brlic P, Kaynan N, Juranic Lisnic V, Brizic I, Jordan S, et al. Inflammatory monocytes and NK cells play a crucial role in DNAM-1-dependent control of cytomegalovirus infection. J Exp Med. 2016;213:1835-50 pubmed 出版商
Finkel P, Frey B, Mayer F, Bösl K, Werthmöller N, Mackensen A, et al. The dual role of NK cells in antitumor reactions triggered by ionizing radiation in combination with hyperthermia. Oncoimmunology. 2016;5:e1101206 pubmed 出版商
Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed 出版商
Demarta Gatsi C, Smith L, Thiberge S, Peronet R, Commere P, Matondo M, et al. Protection against malaria in mice is induced by blood stage-arresting histamine-releasing factor (HRF)-deficient parasites. J Exp Med. 2016;213:1419-28 pubmed 出版商
He Z, Wang F, Ma J, Sen S, Zhang J, Gwack Y, et al. Ubiquitination of ROR?t at Lysine 446 Limits Th17 Differentiation by Controlling Coactivator Recruitment. J Immunol. 2016;197:1148-58 pubmed 出版商
Xu Y, Zhao F, Qiu Q, Chen K, Wei J, Kong Q, et al. The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity. Nat Commun. 2016;7:12073 pubmed 出版商
Venetz D, Koovely D, Weder B, Neri D. Targeted Reconstitution of Cytokine Activity upon Antigen Binding using Split Cytokine Antibody Fusion Proteins. J Biol Chem. 2016;291:18139-47 pubmed 出版商
Menendez C, Jinkins J, Carr D. Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency. J Immunol. 2016;197:1262-75 pubmed 出版商
Deng Z, Rong Y, Teng Y, Zhuang X, Samykutty A, Mu J, et al. Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis. Oncogene. 2017;36:639-651 pubmed 出版商
Lee H, Kim J, Quan W, Lee J, Kim M, Kim S, et al. Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis. Autophagy. 2016;12:1390-403 pubmed 出版商
Brinkman C, Iwami D, Hritzo M, Xiong Y, Ahmad S, Simon T, et al. Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration. Nat Commun. 2016;7:12021 pubmed 出版商
Fernandez D, Flores Santibáñez F, Neira J, Osorio Barrios F, Tejon G, Nuñez S, et al. Purinergic Signaling as a Regulator of Th17 Cell Plasticity. PLoS ONE. 2016;11:e0157889 pubmed 出版商
Stentzel S, Teufelberger A, Nordengrün M, Kolata J, Schmidt F, Van Crombruggen K, et al. Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus. J Allergy Clin Immunol. 2017;139:492-500.e8 pubmed 出版商
Ruhland M, Loza A, Capietto A, Luo X, Knolhoff B, Flanagan K, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nat Commun. 2016;7:11762 pubmed 出版商
Wood M, Goldman N, DePierri K, Somerville J, Riggs J. Erythropoietin increases macrophage-mediated T cell suppression. Cell Immunol. 2016;306-307:17-24 pubmed 出版商
Holmgaard R, Zamarin D, Lesokhin A, Merghoub T, Wolchok J. Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressing tumors. EBioMedicine. 2016;6:50-58 pubmed 出版商
Kawalkowska J, Quirke A, Ghari F, Davis S, Subramanian V, Thompson P, et al. Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses. Sci Rep. 2016;6:26430 pubmed 出版商
Rapp M, Grassmann S, Chaloupka M, Layritz P, Krüger S, Ormanns S, et al. C-C chemokine receptor type-4 transduction of T cells enhances interaction with dendritic cells, tumor infiltration and therapeutic efficacy of adoptive T cell transfer. Oncoimmunology. 2016;5:e1105428 pubmed
Göbel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nat Commun. 2016;7:11626 pubmed 出版商
Collins N, Jiang X, Zaid A, Macleod B, Li J, Park C, et al. Skin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation. Nat Commun. 2016;7:11514 pubmed 出版商
Vandenberk L, Garg A, Verschuere T, Koks C, Belmans J, Beullens M, et al. Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma. Oncoimmunology. 2016;5:e1083669 pubmed
Monticelli L, Buck M, Flamar A, Saenz S, Tait Wojno E, Yudanin N, et al. Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation. Nat Immunol. 2016;17:656-65 pubmed 出版商
Ghari F, Quirke A, Munro S, Kawalkowska J, Picaud S, McGouran J, et al. Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response. Sci Adv. 2016;2:e1501257 pubmed 出版商
Cheng Y, Chikwava K, Wu C, Zhang H, Bhagat A, Pei D, et al. LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors. J Clin Invest. 2016;126:1267-81 pubmed 出版商
Ruck T, Afzali A, Lukat K, Eveslage M, Gross C, Pfeuffer S, et al. ALAIN01--Alemtuzumab in autoimmune inflammatory neurodegeneration: mechanisms of action and neuroprotective potential. BMC Neurol. 2016;16:34 pubmed 出版商
Ingwersen J, Wingerath B, Graf J, Lepka K, Hofrichter M, Schröter F, et al. Dual roles of the adenosine A2a receptor in autoimmune neuroinflammation. J Neuroinflammation. 2016;13:48 pubmed 出版商
Westernberg L, Conche C, Huang Y, Rigaud S, Deng Y, Siegemund S, et al. Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent. elife. 2016;5: pubmed 出版商
Harmon D, Srikakulapu P, Kaplan J, Oldham S, McSkimming C, Garmey J, et al. Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance. Arterioscler Thromb Vasc Biol. 2016;36:682-91 pubmed 出版商
Gillespie A, Teoh J, Lee H, Prince J, Stadnisky M, Anderson M, et al. Genomic Modifiers of Natural Killer Cells, Immune Responsiveness and Lymphoid Tissue Remodeling Together Increase Host Resistance to Viral Infection. PLoS Pathog. 2016;12:e1005419 pubmed 出版商
Lee J, Kannarkat G, Chung J, Joon Lee H, Graham K, Tansey M. RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2016;13:24 pubmed 出版商
Oh J, Kim B, Chang D, Kwon M, Lee S, Kang D, et al. Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa. Proc Natl Acad Sci U S A. 2016;113:E762-71 pubmed 出版商
Wei J, Long L, Yang K, Guy C, Shrestha S, Chen Z, et al. Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis. Nat Immunol. 2016;17:277-85 pubmed 出版商
Coffman L, Choi Y, McLean K, Allen B, di Magliano M, Buckanovich R. Human carcinoma-associated mesenchymal stem cells promote ovarian cancer chemotherapy resistance via a BMP4/HH signaling loop. Oncotarget. 2016;7:6916-32 pubmed 出版商
Milanez Almeida P, Ulas T, Pasztoi M, Glage S, Schughart K, Lutz M, et al. CD11b(+)Ly6C(++)Ly6G(-) Cells with Suppressive Activity Towards T Cells Accumulate in Lungs of Influenza a Virus-Infected Mice. Eur J Microbiol Immunol (Bp). 2015;5:246-55 pubmed 出版商
Mackay L, Wynne Jones E, Freestone D, Pellicci D, Mielke L, Newman D, et al. T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate. Immunity. 2015;43:1101-11 pubmed 出版商
Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani A, et al. Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex. Nat Commun. 2015;6:10181 pubmed 出版商
Intosalmi J, Ahlfors H, Rautio S, Mannerstöm H, Chen Z, Lahesmaa R, et al. Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data. BMC Syst Biol. 2015;9:81 pubmed 出版商
Bhaskaran N, Quigley C, Weinberg A, Huang A, Popkin D, Pandiyan P. Transforming growth factor-β1 sustains the survival of Foxp3(+) regulatory cells during late phase of oropharyngeal candidiasis infection. Mucosal Immunol. 2016;9:1015-26 pubmed 出版商
Lobo P, Schlegel K, Bajwa A, Huang L, Kurmaeva E, Wang B, et al. Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation. J Immunol. 2015;195:5215-26 pubmed 出版商
Ruan S, Samuelson D, Assouline B, Morre M, Shellito J. Treatment with Interleukin-7 Restores Host Defense against Pneumocystis in CD4+ T-Lymphocyte-Depleted Mice. Infect Immun. 2016;84:108-19 pubmed 出版商
Alam M, Gaida M, Bergmann F, Lasitschka F, Giese T, Giese N, et al. Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression. Nat Med. 2015;21:1337-43 pubmed 出版商
Zanvit P, Konkel J, Jiao X, Kasagi S, Zhang D, Wu R, et al. Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis. Nat Commun. 2015;6:8424 pubmed 出版商
Lee J, Dustin M, KAM L. A microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays. Integr Biol (Camb). 2015;7:1442-53 pubmed 出版商
Kawahara M, Takaku H. A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells. Cancer Biol Ther. 2015;16:1616-25 pubmed 出版商
Li W, Liu H. CCL20-CCR6 Cytokine Network Facilitate Treg Activity in Advanced Grades and Metastatic Variants of Hepatocellular Carcinoma. Scand J Immunol. 2016;83:33-7 pubmed 出版商
Wang W, Yen M, Liu K, Hsu P, Lin M, Chen P, et al. Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses. Stem Cell Reports. 2015;5:392-404 pubmed 出版商
Wang X, Huang Z, Chen Y, Lu X, Zhu P, Wen K, et al. A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus. PLoS ONE. 2015;10:e0136888 pubmed 出版商
Kaneko K, Williams R, Dransfield D, Nixon A, Sandison A, Itoh Y. Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade. Arthritis Rheumatol. 2016;68:521-31 pubmed 出版商
Yang B, Hagemann S, Mamareli P, Lauer U, Hoffmann U, Beckstette M, et al. Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation. Mucosal Immunol. 2016;9:444-57 pubmed 出版商
Takada K, Van Laethem F, Xing Y, Akane K, Suzuki H, Murata S, et al. TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8(+) T cells. Nat Immunol. 2015;16:1069-76 pubmed 出版商
Monteiro M, Agua Doce A, Almeida C, Fonseca Pereira D, Veiga Fernandes H, Graca L. IL-9 Expression by Invariant NKT Cells Is Not Imprinted during Thymic Development. J Immunol. 2015;195:3463-71 pubmed 出版商
Derkow K, Krüger C, Dembny P, Lehnardt S. Microglia Induce Neurotoxic IL-17+ γδ T Cells Dependent on TLR2, TLR4, and TLR9 Activation. PLoS ONE. 2015;10:e0135898 pubmed 出版商
Mandl M, Drechsler M, Jansen Y, Neideck C, Noels H, Faussner A, et al. Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation. PLoS ONE. 2015;10:e0134176 pubmed 出版商
Yoon K, Byun S, Kwon E, Hwang S, Chu K, Hiraki M, et al. Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53. Science. 2015;349:1261669 pubmed 出版商
Bittner S, Bobak N, Hofmann M, Schuhmann M, Ruck T, Göbel K, et al. Murine K2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation due to Compensatory K2P3.1- and KV1.3-Dependent Mechanisms. Int J Mol Sci. 2015;16:16880-96 pubmed 出版商
Schumann J, Stanko K, Schliesser U, Appelt C, Sawitzki B. Differences in CD44 Surface Expression Levels and Function Discriminates IL-17 and IFN-γ Producing Helper T Cells. PLoS ONE. 2015;10:e0132479 pubmed 出版商
Kim M, Taparowsky E, Kim C. Retinoic Acid Differentially Regulates the Migration of Innate Lymphoid Cell Subsets to the Gut. Immunity. 2015;43:107-19 pubmed 出版商
Wu J, Waxman D. Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8+ T-cell responses and immune memory. Oncoimmunology. 2015;4:e1005521 pubmed
Vaeth M, Zee I, Concepcion A, Maus M, Shaw P, Portal Celhay C, et al. Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells. J Immunol. 2015;195:1202-17 pubmed 出版商
Rose A, Hoffmann F, Hara J, Urschitz J, Moisyadi S, Hoffmann P, et al. Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses. Hum Vaccin Immunother. 2015;11:2305-11 pubmed 出版商
Dey M, Chang A, Miska J, Wainwright D, Ahmed A, Balyasnikova I, et al. Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma. J Immunol. 2015;195:367-76 pubmed 出版商
Mascanfroni I, Takenaka M, Yeste A, Patel B, Wu Y, Kenison J, et al. Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α. Nat Med. 2015;21:638-46 pubmed 出版商
Uyangaa E, Choi J, Ryu H, Oh S, Eo S. Anti-herpes Activity of Vinegar-processed Daphne genkwa Flos Via Enhancement of Natural Killer Cell Activity. Immune Netw. 2015;15:91-9 pubmed 出版商
Lazear H, Daniels B, Pinto A, Huang A, Vick S, Doyle S, et al. Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier. Sci Transl Med. 2015;7:284ra59 pubmed 出版商
Stubbington M, Mahata B, Svensson V, Deonarine A, Nissen J, Betz A, et al. An atlas of mouse CD4(+) T cell transcriptomes. Biol Direct. 2015;10:14 pubmed 出版商
Gillgrass A, Chew M, Krneta T, Ashkar A. Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model. BMC Cancer. 2015;15:293 pubmed 出版商
Zheng D, Chen H, Bartee M, Williams J, Davids J, Lomas D, et al. Myxomaviral Anti-Inflammatory Serpin Reduces Myeloid-Derived Suppressor Cells and Human Pancreatic Cancer Cell Growth in Mice. J Cancer Sci Ther. 2013;5:291-299 pubmed
Kumari S, Depoil D, Martinelli R, Judokusumo E, Carmona G, Gertler F, et al. Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway. elife. 2015;4: pubmed 出版商
McPherson R, Turner D, Mair I, O Connor R, Anderton S. T-bet Expression by Foxp3(+) T Regulatory Cells is Not Essential for Their Suppressive Function in CNS Autoimmune Disease or Colitis. Front Immunol. 2015;6:69 pubmed 出版商
Gao Y, Yang P, Shen H, Yu H, Song X, Zhang L, et al. Small-molecule inhibitors targeting INK4 protein p18(INK4C) enhance ex vivo expansion of haematopoietic stem cells. Nat Commun. 2015;6:6328 pubmed 出版商
McAlees J, Lajoie S, Dienger K, Sproles A, Richgels P, Yang Y, et al. Differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma. Eur J Immunol. 2015;45:1019-29 pubmed 出版商
Hill E, Ng T, Burton B, Oakley C, Malik K, Wraith D. Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter. Eur J Immunol. 2015;45:1103-15 pubmed 出版商
Chmelova H, Cohrs C, Chouinard J, Petzold C, Kuhn M, Chen C, et al. Distinct roles of β-cell mass and function during type 1 diabetes onset and remission. Diabetes. 2015;64:2148-60 pubmed 出版商
Mooster J, Le Bras S, Massaad M, Jabara H, Yoon J, Galand C, et al. Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα. J Exp Med. 2015;212:185-202 pubmed 出版商
Mackley E, Houston S, Marriott C, Halford E, LUCAS B, Cerovic V, et al. CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes. Nat Commun. 2015;6:5862 pubmed 出版商
Jung Y, Wen T, Mingler M, Caldwell J, Wang Y, Chaplin D, et al. IL-1β in eosinophil-mediated small intestinal homeostasis and IgA production. Mucosal Immunol. 2015;8:930-42 pubmed 出版商
Li C, Lin M, Chu S, Tu P, Fang C, Yen C, et al. Role of glycine N-methyltransferase in the regulation of T-cell responses in experimental autoimmune encephalomyelitis. Mol Med. 2015;20:684-96 pubmed 出版商
Gewies A, Gorka O, Bergmann H, Pechloff K, Petermann F, Jeltsch K, et al. Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation. Cell Rep. 2014;9:1292-305 pubmed 出版商
Sharir R, Semo J, Shimoni S, Ben Mordechai T, Landa Rouben N, Maysel Auslender S, et al. Experimental myocardial infarction induces altered regulatory T cell hemostasis, and adoptive transfer attenuates subsequent remodeling. PLoS ONE. 2014;9:e113653 pubmed 出版商
Kobayashi S, Hara A, Isagawa T, Manabe I, Takeda K, Maruyama T. The nuclear IκB family protein IκBNS influences the susceptibility to experimental autoimmune encephalomyelitis in a murine model. PLoS ONE. 2014;9:e110838 pubmed 出版商
Hou H, Liu W, Wu S, Lu Y, Peng J, Zhu Y, et al. Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock. PLoS ONE. 2014;9:e110585 pubmed 出版商
Jaworski M, Marsland B, Gehrig J, Held W, Favre S, Luther S, et al. Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity. EMBO J. 2014;33:2765-81 pubmed 出版商
Bode C, Wang J, Klinman D. Suppressive oligodeoxynucleotides promote the generation of regulatory T cells by inhibiting STAT1 phosphorylation. Int Immunopharmacol. 2014;23:516-22 pubmed 出版商
Bertin S, Aoki Nonaka Y, de Jong P, Nohara L, Xu H, Stanwood S, et al. The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4? T cells. Nat Immunol. 2014;15:1055-1063 pubmed 出版商
Beale J, Jayaraman A, Jackson D, Macintyre J, Edwards M, Walton R, et al. Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation. Sci Transl Med. 2014;6:256ra134 pubmed 出版商
Guéry L, Dubrot J, Lippens C, Brighouse D, Malinge P, Irla M, et al. Ag-presenting CpG-activated pDCs prime Th17 cells that induce tumor regression. Cancer Res. 2014;74:6430-40 pubmed 出版商
Han S, Melichar H, Coombes J, Chan S, Koshy A, Boothroyd J, et al. Internalization and TLR-dependent type I interferon production by monocytes in response to Toxoplasma gondii. Immunol Cell Biol. 2014;92:872-81 pubmed 出版商
Dai M, Yip Y, Hellstrom I, Hellstrom K. Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies. Clin Cancer Res. 2015;21:1127-38 pubmed 出版商
Li X, Liang Y, Leblanc M, Benner C, Zheng Y. Function of a Foxp3 cis-element in protecting regulatory T cell identity. Cell. 2014;158:734-748 pubmed 出版商
Glick G, Rossignol R, Lyssiotis C, Wahl D, Lesch C, Sanchez B, et al. Anaplerotic metabolism of alloreactive T cells provides a metabolic approach to treat graft-versus-host disease. J Pharmacol Exp Ther. 2014;351:298-307 pubmed 出版商
Saunders A, Shim Y, Johnson P. Innate immune cell CD45 regulates lymphopenia-induced T cell proliferation. J Immunol. 2014;193:2831-42 pubmed 出版商
Cao Y, Rathmell J, Macintyre A. Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. PLoS ONE. 2014;9:e104104 pubmed 出版商
Figueiredo C, Drohomyrecky P, McCarthy S, Leontyev D, Ma X, Branch D, et al. Optimal attenuation of experimental autoimmune encephalomyelitis by intravenous immunoglobulin requires an intact interleukin-11 receptor. PLoS ONE. 2014;9:e101947 pubmed 出版商
Larsen J, Dall M, Antvorskov J, Weile C, Engkilde K, Josefsen K, et al. Dietary gluten increases natural killer cell cytotoxicity and cytokine secretion. Eur J Immunol. 2014;44:3056-67 pubmed 出版商
Mayer C, Ghorbani P, Kuhl A, Stüve P, Hegemann M, Berod L, et al. Few Foxp3⁺ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity. Eur J Immunol. 2014;44:2990-3002 pubmed 出版商
Whitney P, Bär E, Osorio F, Rogers N, Schraml B, Deddouche S, et al. Syk signaling in dendritic cells orchestrates innate resistance to systemic fungal infection. PLoS Pathog. 2014;10:e1004276 pubmed 出版商
Cao Q, Wang Y, Wang X, Lu J, Lee V, Ye Q, et al. Renal F4/80+ CD11c+ mononuclear phagocytes display phenotypic and functional characteristics of macrophages in health and in adriamycin nephropathy. J Am Soc Nephrol. 2015;26:349-63 pubmed 出版商
Costes L, van der Vliet J, Farro G, Matteoli G, van Bree S, Olivier B, et al. The spleen responds to intestinal manipulation but does not participate in the inflammatory response in a mouse model of postoperative ileus. PLoS ONE. 2014;9:e102211 pubmed 出版商
May S, Zhou Q, Lewellen M, Carter C, Coffey D, Highfill S, et al. Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis. PLoS ONE. 2014;9:e100629 pubmed 出版商
Goto M, Takano Ishikawa Y, Nishimoto M, Kitaoka M. Effect of Lacto-N-biose I on the Antigen-specific Immune Responses of Splenocytes. Biosci Microbiota Food Health. 2012;31:47-50 pubmed 出版商
Walch M, Dotiwala F, Mulik S, Thiery J, Kirchhausen T, Clayberger C, et al. Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes. Cell. 2014;157:1309-23 pubmed 出版商
Wang G, Wu K, Li W, Zhao E, Shi L, Wang J, et al. Role of IL-17 and TGF-? in peritoneal adhesion formation after surgical trauma. Wound Repair Regen. 2014;22:631-9 pubmed 出版商
Wang H, Geng J, Wen X, Bi E, Kossenkov A, Wolf A, et al. The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells. Nat Immunol. 2014;15:667-75 pubmed 出版商
Mahata B, Zhang X, Kolodziejczyk A, Proserpio V, Haim Vilmovsky L, Taylor A, et al. Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis. Cell Rep. 2014;7:1130-42 pubmed 出版商
Kong G, Wunderlich M, Yang D, Ranheim E, Young K, Wang J, et al. Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm. J Clin Invest. 2014;124:2762-73 pubmed 出版商
Rocca C, Ur S, Harrison F, Cherqui S. rAAV9 combined with renal vein injection is optimal for kidney-targeted gene delivery: conclusion of a comparative study. Gene Ther. 2014;21:618-28 pubmed 出版商
Mihaly S, Morioka S, Ninomiya Tsuji J, Takaesu G. Activated macrophage survival is coordinated by TAK1 binding proteins. PLoS ONE. 2014;9:e94982 pubmed 出版商
Gerhardt D, Pajcini K, D Altri T, Tu L, Jain R, Xu L, et al. The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells. Genes Dev. 2014;28:576-93 pubmed 出版商
Hart K, Usherwood E, Berwin B. CX3CR1 delineates temporally and functionally distinct subsets of myeloid-derived suppressor cells in a mouse model of ovarian cancer. Immunol Cell Biol. 2014;92:499-508 pubmed 出版商
Jie Z, Liang Y, Hou L, Dong C, Iwakura Y, Soong L, et al. Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection. J Immunol. 2014;192:3289-300 pubmed 出版商
Liu H, Moynihan K, Zheng Y, Szeto G, Li A, Huang B, et al. Structure-based programming of lymph-node targeting in molecular vaccines. Nature. 2014;507:519-22 pubmed 出版商
Sindhava V, Scholz J, Stohl W, Cancro M. APRIL mediates peritoneal B-1 cell homeostasis. Immunol Lett. 2014;160:120-7 pubmed 出版商
Thelemann C, Eren R, Coutaz M, Brasseit J, Bouzourene H, Rosa M, et al. Interferon-? induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis. PLoS ONE. 2014;9:e86844 pubmed 出版商
Akbari M, Honma K, Kimura D, Miyakoda M, Kimura K, Matsuyama T, et al. IRF4 in dendritic cells inhibits IL-12 production and controls Th1 immune responses against Leishmania major. J Immunol. 2014;192:2271-9 pubmed 出版商
Hilgendorf I, Theurl I, Gerhardt L, Robbins C, Weber G, Gonen A, et al. Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity. Circulation. 2014;129:1677-87 pubmed 出版商
Campese A, Grazioli P, De Cesaris P, Riccioli A, Bellavia D, Pelullo M, et al. Mouse Sertoli cells sustain de novo generation of regulatory T cells by triggering the notch pathway through soluble JAGGED1. Biol Reprod. 2014;90:53 pubmed 出版商
Yamamoto H, Nakamura Y, Sato K, Takahashi Y, Nomura T, Miyasaka T, et al. Defect of CARD9 leads to impaired accumulation of gamma interferon-producing memory phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans. Infect Immun. 2014;82:1606-15 pubmed 出版商
Ribes S, Meister T, Ott M, Redlich S, Janova H, Hanisch U, et al. Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection. J Neuroinflammation. 2014;11:14 pubmed 出版商
Leigh N, Bian G, Ding X, Liu H, Aygun Sunar S, Burdelya L, et al. A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity. PLoS ONE. 2014;9:e85587 pubmed 出版商
Torabi Parizi P, Vrisekoop N, Kastenmuller W, Gerner M, Egen J, Germain R. Pathogen-related differences in the abundance of presented antigen are reflected in CD4+ T cell dynamic behavior and effector function in the lung. J Immunol. 2014;192:1651-1660 pubmed 出版商
Prajeeth C, Löhr K, Floess S, Zimmermann J, Ulrich R, Gudi V, et al. Effector molecules released by Th1 but not Th17 cells drive an M1 response in microglia. Brain Behav Immun. 2014;37:248-59 pubmed 出版商
Norrie I, Ohlsson E, Nielsen O, Hasemann M, Porse B. C/EBP? is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner. PLoS ONE. 2014;9:e84728 pubmed 出版商
Qin X, Liu X, Shan B, Shi L, Sharma S, Wu J, et al. Inhibition of eIF5A results in aberrant uterine natural killer cell function and embryo loss in mice. Am J Reprod Immunol. 2014;71:229-40 pubmed 出版商
Zhang B, Yin Y, Lai R, Tan S, Choo A, Lim S. Mesenchymal stem cells secrete immunologically active exosomes. Stem Cells Dev. 2014;23:1233-44 pubmed 出版商
Eitas T, Chou W, Wen H, Gris D, Robbins G, Brickey J, et al. The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation. J Biol Chem. 2014;289:4173-9 pubmed 出版商
Haastert B, Mellanby R, Anderton S, O Connor R. T cells at the site of autoimmune inflammation show increased potential for trogocytosis. PLoS ONE. 2013;8:e81404 pubmed 出版商
Shubin N, Monaghan S, Heffernan D, Chung C, Ayala A. B and T lymphocyte attenuator expression on CD4+ T-cells associates with sepsis and subsequent infections in ICU patients. Crit Care. 2013;17:R276 pubmed 出版商
Leyva Castillo J, Hener P, Michea P, Karasuyama H, Chan S, Soumelis V, et al. Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade. Nat Commun. 2013;4:2847 pubmed 出版商
Saucillo D, Gerriets V, Sheng J, Rathmell J, Maciver N. Leptin metabolically licenses T cells for activation to link nutrition and immunity. J Immunol. 2014;192:136-44 pubmed 出版商
Dey M, Chang A, Wainwright D, Ahmed A, Han Y, Balyasnikova I, et al. Heme oxygenase-1 protects regulatory T cells from hypoxia-induced cellular stress in an experimental mouse brain tumor model. J Neuroimmunol. 2014;266:33-42 pubmed 出版商
Hofmann C, Dunger N, Doser K, Lippert E, Siller S, Edinger M, et al. Physiologic TLR9-CpG-DNA interaction is essential for the homeostasis of the intestinal immune system. Inflamm Bowel Dis. 2014;20:136-43 pubmed 出版商
Seach N, Guerri L, Le Bourhis L, Mburu Y, Cui Y, Bessoles S, et al. Double-positive thymocytes select mucosal-associated invariant T cells. J Immunol. 2013;191:6002-9 pubmed 出版商
Almena M, Andrada E, Liébana R, Merida I. Diacylglycerol metabolism attenuates T-cell receptor signaling and alters thymocyte differentiation. Cell Death Dis. 2013;4:e912 pubmed 出版商
Ramon S, Bancos S, Serhan C, Phipps R. Lipoxin A? modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism. Eur J Immunol. 2014;44:357-69 pubmed
Friend S, Peterson L, Treacy E, Stefanski A, Sosinowski T, Pennock N, et al. The discovery of a reciprocal relationship between tyrosine-kinase signaling and cullin neddylation. PLoS ONE. 2013;8:e75200 pubmed 出版商
Alhajjat A, Strong B, Durkin E, Turner L, Wadhwani R, Midura E, et al. Trogocytosis as a mechanistic link between chimerism and prenatal tolerance. Chimerism. 2013;4:126-31 pubmed 出版商
Yamamoto K, Tsuzuki S, Minami Y, Yamamoto Y, Abe A, Ohshima K, et al. Functionally deregulated AML1/RUNX1 cooperates with BCR-ABL to induce a blastic phase-like phenotype of chronic myelogenous leukemia in mice. PLoS ONE. 2013;8:e74864 pubmed 出版商
Ichim C, Dervovic D, Zuniga Pflucker J, Wells R. The orphan nuclear receptor Ear-2 (Nr2f6) is a novel negative regulator of T cell development. Exp Hematol. 2014;42:46-58 pubmed 出版商
Fleischman A, Maxson J, Luty S, Agarwal A, Royer L, Abel M, et al. The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition. Blood. 2013;122:3628-31 pubmed 出版商
Mayer C, Tian L, Hesse C, Kühl A, Swallow M, Kruse F, et al. Anti-CD4 treatment inhibits autoimmunity in scurfy mice through the attenuation of co-stimulatory signals. J Autoimmun. 2014;50:23-32 pubmed 出版商
Zhong M, Veillette A. The adaptor molecule signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) is essential in mechanisms involving the Fyn tyrosine kinase for induction and progression of collagen-induced arthritis. J Biol Chem. 2013;288:31423-36 pubmed 出版商
Guo Z, Cheng D, Xia Z, Luan M, Wu L, Wang G, et al. Combined TIM-3 blockade and CD137 activation affords the long-term protection in a murine model of ovarian cancer. J Transl Med. 2013;11:215 pubmed 出版商
Carbo A, Bassaganya Riera J, Pedragosa M, Viladomiu M, Marathe M, Eubank S, et al. Predictive computational modeling of the mucosal immune responses during Helicobacter pylori infection. PLoS ONE. 2013;8:e73365 pubmed 出版商
Frazer L, Sullivan J, Zurenski M, Mintus M, Tomasak T, Prantner D, et al. CD4+ T cell expression of MyD88 is essential for normal resolution of Chlamydia muridarum genital tract infection. J Immunol. 2013;191:4269-79 pubmed 出版商
Chen Y, Forsberg M, Khaja S, Ciecko A, Hessner M, Geurts A. Gene targeting in NOD mouse embryos using zinc-finger nucleases. Diabetes. 2014;63:68-74 pubmed 出版商
Nishimoto S, Kotani H, Tsuruta S, Shimizu N, Ito M, Shichita T, et al. Th17 cells carrying TCR recognizing epidermal autoantigen induce psoriasis-like skin inflammation. J Immunol. 2013;191:3065-72 pubmed 出版商
Heymans S, Corsten M, Verhesen W, Carai P, van Leeuwen R, Custers K, et al. Macrophage microRNA-155 promotes cardiac hypertrophy and failure. Circulation. 2013;128:1420-32 pubmed 出版商
Imai T, Koyanagi N, Ogawa R, Shindo K, Suenaga T, Sato A, et al. Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cells. PLoS ONE. 2013;8:e72050 pubmed 出版商
Taylor A, Sheng K, Herrero L, Chen W, Rulli N, Mahalingam S. Methotrexate treatment causes early onset of disease in a mouse model of Ross River virus-induced inflammatory disease through increased monocyte production. PLoS ONE. 2013;8:e71146 pubmed 出版商
Bittner Eddy P, Fischer L, Costalonga M. Identification of gingipain-specific I-A(b) -restricted CD4+ T cells following mucosal colonization with Porphyromonas gingivalis in C57BL/6 mice. Mol Oral Microbiol. 2013;28:452-66 pubmed 出版商
Wege A, Huber B, Wimmer N, Männel D, Hehlgans T. LT?R expression on hematopoietic cells regulates acute inflammation and influences maturation of myeloid subpopulations. Innate Immun. 2014;20:461-70 pubmed 出版商
Grishkan I, Ntranos A, Calabresi P, Gocke A. Helper T cells down-regulate CD4 expression upon chronic stimulation giving rise to double-negative T cells. Cell Immunol. 2013;284:68-74 pubmed 出版商
Dugger K, Chrisman T, Jones B, Chastain P, Watson K, Estell K, et al. Moderate aerobic exercise alters migration patterns of antigen specific T helper cells within an asthmatic lung. Brain Behav Immun. 2013;34:67-78 pubmed 出版商
Ohsugi T, Wakamiya M, Morikawa S, Matsuura K, Kumar J, Kumasaka T, et al. Invasion of histiocytic sarcoma into the spinal cord of HTLV-1 tax transgenic mice with HTLV-1-associated myelopathy/tropical spastic paraparesis-like disease. Oncol Res. 2013;20:403-10 pubmed 出版商
Guo Y, Sun X, Shibata K, Yamada H, Muta H, Podack E, et al. CD30 is required for activation of a unique subset of interleukin-17A-producing ?? T cells in innate immunity against Mycobacterium bovis Bacillus Calmette-Guerin infection. Infect Immun. 2013;81:3923-34 pubmed 出版商
Ieronimakis N, Pantoja M, Hays A, Dosey T, Qi J, Fischer K, et al. Increased sphingosine-1-phosphate improves muscle regeneration in acutely injured mdx mice. Skelet Muscle. 2013;3:20 pubmed 出版商
Barao I, Wright P, Sungur C, Anderson S, Redelman D, Murphy W. Differential expression of the Ly49G(B6), but not the Ly49G(BALB), receptor isoform during natural killer cell reconstitution after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2013;19:1446-52 pubmed 出版商
Ding L, Chen T, Wang X, Zhou L, Shi A, Ning Q. CD69+NK cells contribute to the murine hepatitis virus strain 3-induced murine hepatitis. J Huazhong Univ Sci Technolog Med Sci. 2013;33:505-510 pubmed 出版商
Herrero L, Sheng K, Jian P, Taylor A, Her Z, Herring B, et al. Macrophage migration inhibitory factor receptor CD74 mediates alphavirus-induced arthritis and myositis in murine models of alphavirus infection. Arthritis Rheum. 2013;65:2724-36 pubmed 出版商
Flaczyk A, Duerr C, Shourian M, Lafferty E, Fritz J, Qureshi S. IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans. J Immunol. 2013;191:2503-13 pubmed 出版商
Noonan T, Lukas S, Peet G, Pelletier J, Panzenbeck M, Hanidu A, et al. The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function. Am J Clin Exp Immunol. 2013;2:172-85 pubmed
Yoshida A, Kato J, Nakamae I, Yoneda Kato N. COP1 targets C/EBP? for degradation and induces acute myeloid leukemia via Trib1. Blood. 2013;122:1750-60 pubmed 出版商
Heinrichs S, Conover L, Bueso Ramos C, Kilpivaara O, Stevenson K, Neuberg D, et al. MYBL2 is a sub-haploinsufficient tumor suppressor gene in myeloid malignancy. elife. 2013;2:e00825 pubmed 出版商
Monk J, Hou T, Turk H, McMurray D, Chapkin R. n3 PUFAs reduce mouse CD4+ T-cell ex vivo polarization into Th17 cells. J Nutr. 2013;143:1501-8 pubmed 出版商
Stokes K, Currier M, Sakamoto K, Lee S, Collins P, Plemper R, et al. The respiratory syncytial virus fusion protein and neutrophils mediate the airway mucin response to pathogenic respiratory syncytial virus infection. J Virol. 2013;87:10070-82 pubmed 出版商
Rattazzi L, Piras G, Ono M, Deacon R, Pariante C, D Acquisto F. CD4? but not CD8? T cells revert the impaired emotional behavior of immunocompromised RAG-1-deficient mice. Transl Psychiatry. 2013;3:e280 pubmed 出版商
Yau I, Cato M, Jellusova J, Hurtado de Mendoza T, Brink R, Rickert R. Censoring of self-reactive B cells by follicular dendritic cell-displayed self-antigen. J Immunol. 2013;191:1082-90 pubmed 出版商
Wensveen F, Lenartic M, Jelencic V, Lemmermann N, ten Brinke A, Jonjic S, et al. NKG2D induces Mcl-1 expression and mediates survival of CD8 memory T cell precursors via phosphatidylinositol 3-kinase. J Immunol. 2013;191:1307-15 pubmed 出版商
Haasken S, Auger J, Taylor J, Hobday P, Goudy B, Titcombe P, et al. Macrophage scavenger receptor 1 (Msr1, SR-A) influences B cell autoimmunity by regulating soluble autoantigen concentration. J Immunol. 2013;191:1055-62 pubmed 出版商
Wang J, Shan Y, Jiang Z, Feng J, Li C, Ma L, et al. High frequencies of activated B cells and T follicular helper cells are correlated with disease activity in patients with new-onset rheumatoid arthritis. Clin Exp Immunol. 2013;174:212-20 pubmed 出版商
Goto R, You S, Zaitsu M, Chatenoud L, Wood K. Delayed anti-CD3 therapy results in depletion of alloreactive T cells and the dominance of Foxp3+ CD4+ graft infiltrating cells. Am J Transplant. 2013;13:1655-64 pubmed 出版商
Engel A, Sun G, Gad E, Rastetter L, Strobe K, Yang Y, et al. Protein-bound polysaccharide activates dendritic cells and enhances OVA-specific T cell response as vaccine adjuvant. Immunobiology. 2013;218:1468-76 pubmed 出版商
Li J, Heinrichs J, Leconte J, Haarberg K, Semple K, Liu C, et al. Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice. J Immunol. 2013;191:200-7 pubmed 出版商
Roychoudhuri R, Hirahara K, Mousavi K, Clever D, Klebanoff C, Bonelli M, et al. BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis. Nature. 2013;498:506-10 pubmed 出版商
Jabara H, Ohsumi T, Chou J, Massaad M, Benson H, Megarbane A, et al. A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency. J Allergy Clin Immunol. 2013;132:151-8 pubmed 出版商
Kühlhorn F, Rath M, Schmoeckel K, Cziupka K, Nguyen H, Hildebrandt P, et al. Foxp3+ regulatory T cells are required for recovery from severe sepsis. PLoS ONE. 2013;8:e65109 pubmed 出版商
Bae J, Koo J, Kim S, Park T, Kim M. Ginsenoside Rp1 Exerts Anti-inflammatory Effects via Activation of Dendritic Cells and Regulatory T Cells. J Ginseng Res. 2012;36:375-82 pubmed 出版商
Jeon C, Kang S, Park S, Lim K, Hwang K, Min H. T Cell Stimulatory Effects of Korean Red Ginseng through Modulation of Myeloid-Derived Suppressor Cells. J Ginseng Res. 2011;35:462-70 pubmed 出版商
Cheng H, Wu R, Gebre A, Hanna R, Smith D, Parks J, et al. Increased cholesterol content in gammadelta (??) T lymphocytes differentially regulates their activation. PLoS ONE. 2013;8:e63746 pubmed 出版商
Kuriya G, Uchida T, Akazawa S, Kobayashi M, Nakamura K, Satoh T, et al. Double deficiency in IL-17 and IFN-? signalling significantly suppresses the development of diabetes in the NOD mouse. Diabetologia. 2013;56:1773-80 pubmed 出版商
Jordan S, Ruzsics Z, Mitrović M, Baranek T, Arapović J, Krmpotić A, et al. Natural killer cells are required for extramedullary hematopoiesis following murine cytomegalovirus infection. Cell Host Microbe. 2013;13:535-545 pubmed 出版商
Singh R, Franke K, Kalucka J, Mamlouk S, Muschter A, Gembarska A, et al. HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress. Blood. 2013;121:5158-66 pubmed 出版商
Yoshida H, Kotani H, Kondo T, Tani I, Wei X, Tsuruta S, et al. CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice. Biochem Biophys Res Commun. 2013;435:378-84 pubmed 出版商
Inafuku M, Nagao K, Inafuku A, Yanagita T, Taira N, Toda T, et al. Dietary phosphatidylinositol protects C57BL/6 mice from concanavalin A-induced liver injury by modulating immune cell functions. Mol Nutr Food Res. 2013;57:1671-9 pubmed 出版商
Ohta S, Imamura M, Xing W, Boyce J, Balestrieri B. Group V secretory phospholipase A2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation. J Immunol. 2013;190:5927-38 pubmed 出版商
Hasan Z, Palani K, Zhang S, Lepsenyi M, Hwaiz R, Rahman M, et al. Rho kinase regulates induction of T-cell immune dysfunction in abdominal sepsis. Infect Immun. 2013;81:2499-506 pubmed 出版商
Liang Y, Jie Z, Hou L, Aguilar Valenzuela R, Vu D, Soong L, et al. IL-33 induces nuocytes and modulates liver injury in viral hepatitis. J Immunol. 2013;190:5666-75 pubmed 出版商
Shimizu K, Asakura M, Shinga J, Sato Y, Kitahara S, Hoshino K, et al. Invariant NKT cells induce plasmacytoid dendritic cell (DC) cross-talk with conventional DCs for efficient memory CD8+ T cell induction. J Immunol. 2013;190:5609-19 pubmed 出版商
Lee I, Wang X, Hao J, Akhoundsadegh N, Chen L, Liu L, et al. B7-H4.Ig inhibits the development of type 1 diabetes by regulating Th17 cells in NOD mice. Cell Immunol. 2013;282:1-8 pubmed 出版商
Chiang Y, Ho K, Sun C, Chiu J, Lee F, Liao F, et al. CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. PLoS ONE. 2013;8:e61761 pubmed 出版商
Kearl T, Jing W, Gershan J, Johnson B. Programmed death receptor-1/programmed death receptor ligand-1 blockade after transient lymphodepletion to treat myeloma. J Immunol. 2013;190:5620-8 pubmed 出版商
Hu J, Zhang L, Wang N, Ding R, Cui S, Zhu F, et al. Mesenchymal stem cells attenuate ischemic acute kidney injury by inducing regulatory T cells through splenocyte interactions. Kidney Int. 2013;84:521-31 pubmed 出版商
Yang Q, Monticelli L, Saenz S, Chi A, Sonnenberg G, Tang J, et al. T cell factor 1 is required for group 2 innate lymphoid cell generation. Immunity. 2013;38:694-704 pubmed 出版商
Loubaki L, Tremblay T, Bazin R. In vivo depletion of leukocytes and platelets following injection of T cell-specific antibodies into mice. J Immunol Methods. 2013;393:38-44 pubmed 出版商
Ammann J, Cooke A, Trowsdale J. Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes. J Immunol. 2013;190:5030-6 pubmed 出版商
Selemidis S, Seow H, Broughton B, Vinh A, Bozinovski S, Sobey C, et al. Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress. PLoS ONE. 2013;8:e60792 pubmed 出版商
Ryan S, Johnson J, Cobb B. Neutrophils confer T cell resistance to myeloid-derived suppressor cell-mediated suppression to promote chronic inflammation. J Immunol. 2013;190:5037-47 pubmed 出版商
Yao C, Hirata T, Soontrapa K, Ma X, Takemori H, Narumiya S. Prostaglandin E? promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase. Nat Commun. 2013;4:1685 pubmed 出版商
Mullaly S, Oudhoff M, Min P, Burrows K, Antignano F, Rattray D, et al. Requirement for core 2 O-glycans for optimal resistance to helminth infection. PLoS ONE. 2013;8:e60124 pubmed 出版商
Schenkel J, Fraser K, Vezys V, Masopust D. Sensing and alarm function of resident memory CD8? T cells. Nat Immunol. 2013;14:509-13 pubmed 出版商
Cowan J, Parnell S, Nakamura K, Caamano J, Lane P, Jenkinson E, et al. The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development. J Exp Med. 2013;210:675-81 pubmed 出版商
Barrigan L, Tuladhar S, Brunton J, Woolard M, Chen C, Saini D, et al. Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response. Infect Immun. 2013;81:2028-42 pubmed 出版商
Beijer M, Molenaar R, Goverse G, Mebius R, Kraal G, den Haan J. A crucial role for retinoic acid in the development of Notch-dependent murine splenic CD8- CD4- and CD4+ dendritic cells. Eur J Immunol. 2013;43:1608-16 pubmed 出版商
Abadi Y, Jeon H, Ohaegbulam K, Scandiuzzi L, Ghosh K, Hofmeyer K, et al. Host b7x promotes pulmonary metastasis of breast cancer. J Immunol. 2013;190:3806-14 pubmed 出版商
Lewis N, Haxhinasto S, Anderson S, Stefanopoulos D, Fogal S, Adusumalli P, et al. Circulating monocytes are reduced by sphingosine-1-phosphate receptor modulators independently of S1P3. J Immunol. 2013;190:3533-40 pubmed 出版商
Beachy S, Onozawa M, Silverman D, Chung Y, Rivera M, Aplan P. Isolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia. Exp Hematol. 2013;41:518-529.e5 pubmed 出版商
Jessen B, Bode S, Ammann S, Chakravorty S, Davies G, Diestelhorst J, et al. The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2. Blood. 2013;121:2943-51 pubmed 出版商
Mc Guire C, Wieghofer P, Elton L, Muylaert D, Prinz M, Beyaert R, et al. Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination. J Immunol. 2013;190:2896-903 pubmed 出版商
Lee T, Lee E, Irwin R, Lucas P, McCabe L, Parameswaran N. ?-Arrestin-1 deficiency protects mice from experimental colitis. Am J Pathol. 2013;182:1114-23 pubmed 出版商
Kathania M, Zadeh M, Lightfoot Y, Roman R, Sahay B, Abbott J, et al. Colonic immune stimulation by targeted oral vaccine. PLoS ONE. 2013;8:e55143 pubmed 出版商
Zhu M, Nagavalli A, Su M. Aire deficiency promotes TRP-1-specific immune rejection of melanoma. Cancer Res. 2013;73:2104-16 pubmed 出版商
Liu B, Liu Y, Du Y, Mardaryev A, Yang W, Chen H, et al. Cbx4 regulates the proliferation of thymic epithelial cells and thymus function. Development. 2013;140:780-8 pubmed 出版商
Dillon T, Takahashi M, Li Y, Tavisala S, Murray S, Moran A, et al. B-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cells. Int Immunol. 2013;25:259-69 pubmed 出版商
Yamamoto M, Seki Y, Iwai K, Ko I, Martin A, Tsuji N, et al. Ontogeny and localization of the cells produce IL-2 in healthy animals. Cytokine. 2013;61:831-41 pubmed 出版商
Izhak L, Ambrosino E, Kato S, Parish S, O Konek J, Weber H, et al. Delicate balance among three types of T cells in concurrent regulation of tumor immunity. Cancer Res. 2013;73:1514-23 pubmed 出版商
Gautier E, Westerterp M, Bhagwat N, Cremers S, Shih A, Abdel Wahab O, et al. HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders. J Exp Med. 2013;210:339-53 pubmed 出版商
Zhong M, Veillette A. Critical role of SAP in progression and reactivation but not maintenance of T cell-dependent humoral immunity. Mol Cell Biol. 2013;33:1223-32 pubmed 出版商
Yan X, Shichita T, Katsumata Y, Matsuhashi T, Ito H, Ito K, et al. Deleterious effect of the IL-23/IL-17A axis and ??T cells on left ventricular remodeling after myocardial infarction. J Am Heart Assoc. 2012;1:e004408 pubmed 出版商
Lemke C, Geary S, Joshi V, Salem A. Antigen-coated poly ?-hydroxy acid based microparticles for heterologous prime-boost adenovirus based vaccinations. Biomaterials. 2013;34:2524-9 pubmed 出版商
Ma D, Suthar M, Kasahara S, Gale M, Clark E. CD22 is required for protection against West Nile virus Infection. J Virol. 2013;87:3361-75 pubmed 出版商
Almeida A, Arroz Madeira S, Fonseca Pereira D, Ribeiro H, Lasrado R, Pachnis V, et al. RET/GFR? signals are dispensable for thymic T cell development in vivo. PLoS ONE. 2012;7:e52949 pubmed 出版商
Gujar S, Dielschneider R, Clements D, Helson E, Shmulevitz M, Marcato P, et al. Multifaceted therapeutic targeting of ovarian peritoneal carcinomatosis through virus-induced immunomodulation. Mol Ther. 2013;21:338-47 pubmed 出版商
Massilamany C, Gangaplara A, Kim H, Stanford C, Rathnaiah G, Steffen D, et al. Copper-zinc superoxide dismutase-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis induced with myelin oligodendrocyte glycoprotein 35-55. J Neuroimmunol. 2013;256:19-27 pubmed 出版商
Chao L, Soto E, Hong C, Ito A, Pei L, Chawla A, et al. Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice. J Lipid Res. 2013;54:806-15 pubmed 出版商
Baine I, Basu S, Ames R, Sellers R, Macian F. Helios induces epigenetic silencing of IL2 gene expression in regulatory T cells. J Immunol. 2013;190:1008-16 pubmed 出版商
Althof N, Whitton J. Coxsackievirus B3 infects the bone marrow and diminishes the restorative capacity of erythroid and lymphoid progenitors. J Virol. 2013;87:2823-34 pubmed 出版商
Franke K, Kalucka J, Mamlouk S, Singh R, Muschter A, Weidemann A, et al. HIF-1? is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2?-induced excessive erythropoiesis. Blood. 2013;121:1436-45 pubmed 出版商
Piao X, Komazawa Sakon S, Nishina T, Koike M, Piao J, Ehlken H, et al. c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis. Sci Signal. 2012;5:ra93 pubmed 出版商
Hou L, Jie Z, Desai M, Liang Y, Soong L, Wang T, et al. Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis. J Immunol. 2013;190:621-9 pubmed 出版商
Yan L, Singh L, Zhang L, Xu Y. Role of OGR1 in myeloid-derived cells in prostate cancer. Oncogene. 2014;33:157-64 pubmed 出版商
Schmitt D, O Dee D, Brown M, Horzempa J, Russo B, Morel P, et al. Role of NK cells in host defense against pulmonary type A Francisella tularensis infection. Microbes Infect. 2013;15:201-11 pubmed 出版商
Barr K, Jing W, Hallett W, Gershan J, Johnson B. Examining T cells at vaccine sites of tumor-bearing hosts provides insights to dysfunctional T-cell immunity. J Immunother. 2013;36:41-51 pubmed 出版商
Teo T, Lum F, Claser C, Lulla V, Lulla A, Merits A, et al. A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice. J Immunol. 2013;190:259-69 pubmed 出版商
Cohen N, Brennan P, Shay T, Watts G, Brigl M, Kang J, et al. Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells. Nat Immunol. 2013;14:90-9 pubmed 出版商
Majowicz A, van der Marel S, te Velde A, Meijer S, Petry H, van Deventer S, et al. Murine CD4?CD25? cells activated in vitro with PMA/ionomycin and anti-CD3 acquire regulatory function and ameliorate experimental colitis in vivo. BMC Gastroenterol. 2012;12:172 pubmed 出版商
Wu C, Yang C, Chen Y, Chen C, Chen L, Kuo M. The DNA methylation inhibitor 5-azacytidine increases regulatory T cells and alleviates airway inflammation in ovalbumin-sensitized mice. Int Arch Allergy Immunol. 2013;160:356-64 pubmed 出版商
Duffy D, Perrin H, Abadie V, Benhabilès N, Boissonnas A, Liard C, et al. Neutrophils transport antigen from the dermis to the bone marrow, initiating a source of memory CD8+ T cells. Immunity. 2012;37:917-29 pubmed 出版商
Richmond J, Lee J, Green D, Kornfeld H, Cruikshank W. Mannose-capped lipoarabinomannan from Mycobacterium tuberculosis preferentially inhibits sphingosine-1-phosphate-induced migration of Th1 cells. J Immunol. 2012;189:5886-95 pubmed 出版商
Gong Y, Wang Z, Liang Z, Duan H, Ouyang L, Yu Q, et al. Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells. PLoS ONE. 2012;7:e47435 pubmed 出版商
Lee C, Hsu S, Jong Y, Hung C, Suen J. Inhibition of histamine H1 receptor activity modulates proinflammatory cytokine production of dendritic cells through c-Rel activity. Int Arch Allergy Immunol. 2013;160:265-74 pubmed 出版商
Hackstein H, Wachtendorf A, Kranz S, Lohmeyer J, Bein G, Baal N. Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains. Respir Res. 2012;13:94 pubmed 出版商
Ding X, Bian G, Leigh N, Qiu J, McCarthy P, Liu H, et al. A TLR5 agonist enhances CD8(+) T cell-mediated graft-versus-tumor effect without exacerbating graft-versus-host disease. J Immunol. 2012;189:4719-27 pubmed 出版商
Schulz V, Smit J, Bol Schoenmakers M, van Duursen M, Van den Berg M, Pieters R. Activation of the aryl hydrocarbon receptor reduces the number of precursor and effector T cells, but preserves thymic CD4+CD25+Foxp3+ regulatory T cells. Toxicol Lett. 2012;215:100-9 pubmed 出版商
Ramon S, Bancos S, Thatcher T, Murant T, Moshkani S, Sahler J, et al. Peroxisome proliferator-activated receptor ? B cell-specific-deficient mice have an impaired antibody response. J Immunol. 2012;189:4740-7 pubmed 出版商
Zhao J, Zhao J, Perlman S. Differential effects of IL-12 on Tregs and non-Treg T cells: roles of IFN-?, IL-2 and IL-2R. PLoS ONE. 2012;7:e46241 pubmed 出版商
Blasius A, Krebs P, Sullivan B, Oldstone M, Popkin D. Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection. PLoS Pathog. 2012;8:e1002915 pubmed 出版商
Byun J, Suh Y, Yi H, Lee Y, Jeong W. Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating Kupffer cells and stellate cells to produce interleukin-10 in mice. J Hepatol. 2013;58:342-9 pubmed 出版商
Yao Y, Han W, Liang J, Ji J, Wang J, Cantor H, et al. Glatiramer acetate ameliorates inflammatory bowel disease in mice through the induction of Qa-1-restricted CD8? regulatory cells. Eur J Immunol. 2013;43:125-36 pubmed 出版商
Kulhankova K, Rouse T, Nasr M, Field E. Dendritic cells control CD4+CD25+ Treg cell suppressor function in vitro through juxtacrine delivery of IL-2. PLoS ONE. 2012;7:e43609 pubmed 出版商
Hall A, Beiting D, Tato C, John B, Oldenhove G, Lombana C, et al. The cytokines interleukin 27 and interferon-? promote distinct Treg cell populations required to limit infection-induced pathology. Immunity. 2012;37:511-23 pubmed 出版商
Hagman D, Kuzma J, Larson I, Foster Schubert K, Kuan L, Cignarella A, et al. Characterizing and quantifying leukocyte populations in human adipose tissue: impact of enzymatic tissue processing. J Immunol Methods. 2012;386:50-9 pubmed 出版商
Dickgreber N, Farrand K, van Panhuys N, Knight D, McKee S, Chong M, et al. Immature murine NKT cells pass through a stage of developmentally programmed innate IL-4 secretion. J Leukoc Biol. 2012;92:999-1009 pubmed 出版商
Schuettpelz L, Gopalan P, Giuste F, Romine M, van Os R, Link D. Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function. Blood. 2012;120:2981-9 pubmed 出版商
Garaycoechea J, Crossan G, Langevin F, Daly M, Arends M, Patel K. Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function. Nature. 2012;489:571-5 pubmed 出版商
Jin J, Han X, Yu Q. Interleukin-6 induces the generation of IL-10-producing Tr1 cells and suppresses autoimmune tissue inflammation. J Autoimmun. 2013;40:28-44 pubmed 出版商
Barrett O, Sottocornola R, Lo Celso C. In vivo imaging of hematopoietic stem cells in the bone marrow niche. Methods Mol Biol. 2012;916:231-42 pubmed 出版商
Barnes M, Griseri T, Johnson A, Young W, Powrie F, Izcue A. CTLA-4 promotes Foxp3 induction and regulatory T cell accumulation in the intestinal lamina propria. Mucosal Immunol. 2013;6:324-34 pubmed 出版商
Bezman N, Kim C, Sun J, Min oo G, Hendricks D, Kamimura Y, et al. Molecular definition of the identity and activation of natural killer cells. Nat Immunol. 2012;13:1000-9 pubmed 出版商
Zhao D, Zhang M, Wang M, Liu B, Wang X, Yang J, et al. Up-regulation of Cbl-b is associated with LSECtin-mediated inhibition of different CD4+ T-cell subsets. Immunobiology. 2013;218:602-8 pubmed 出版商
Glatman Zaretsky A, Silver J, Siwicki M, Durham A, Ware C, Hunter C. Infection with Toxoplasma gondii alters lymphotoxin expression associated with changes in splenic architecture. Infect Immun. 2012;80:3602-10 pubmed 出版商
Xiao X, Balasubramanian S, Liu W, Chu X, Wang H, Taparowsky E, et al. OX40 signaling favors the induction of T(H)9 cells and airway inflammation. Nat Immunol. 2012;13:981-90 pubmed 出版商
Jeisy Scott V, Kim J, Davis W, Cao W, Katz J, Sambhara S. TLR7 recognition is dispensable for influenza virus A infection but important for the induction of hemagglutinin-specific antibodies in response to the 2009 pandemic split vaccine in mice. J Virol. 2012;86:10988-98 pubmed
Goulding J, Bogue R, Tahiliani V, Croft M, Salek Ardakani S. CD8 T cells are essential for recovery from a respiratory vaccinia virus infection. J Immunol. 2012;189:2432-40 pubmed 出版商
Wang X, Sun R, Wei H, Tian Z. High-mobility group box 1 (HMGB1)-Toll-like receptor (TLR)4-interleukin (IL)-23-IL-17A axis in drug-induced damage-associated lethal hepatitis: Interaction of ?? T cells with macrophages. Hepatology. 2013;57:373-84 pubmed 出版商
Tang F, Wu Q, Ikenoue T, Guan K, Liu Y, Zheng P. A critical role for Rictor in T lymphopoiesis. J Immunol. 2012;189:1850-7 pubmed 出版商
Iwabuchi N, Yonezawa S, Odamaki T, Yaeshima T, Iwatsuki K, Xiao J. Immunomodulating and anti-infective effects of a novel strain of Lactobacillus paracasei that strongly induces interleukin-12. FEMS Immunol Med Microbiol. 2012;66:230-9 pubmed 出版商
Coquery C, Loo W, Buszko M, Lannigan J, Erickson L. Optimized protocol for the isolation of spleen-resident murine neutrophils. Cytometry A. 2012;81:806-14 pubmed 出版商
Baeke F, Van Belle T, Takiishi T, Ding L, Korf H, Laureys J, et al. Low doses of anti-CD3, ciclosporin A and the vitamin D analogue, TX527, synergise to delay recurrence of autoimmune diabetes in an islet-transplanted NOD mouse model of diabetes. Diabetologia. 2012;55:2723-2732 pubmed 出版商
Zhao G, Lu Z, Tang L, Wu Z, Wang D, Zheng J, et al. Curcumin inhibits suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro. Int Immunopharmacol. 2012;14:99-106 pubmed 出版商
Fiole D, Touvrey C, Quesnel Hellmann A, Douady J, Tournier J. Shape-based tracking allows functional discrimination of two immune cell subsets expressing the same fluorescent tag in mouse lung explant. PLoS ONE. 2012;7:e39831 pubmed 出版商
Kim J, Cha H, Kim E, Kweon M. Pathological effect of IL-17A-producing TCR??(+) T cells in mouse genital mucosa against HSV-2 infection. Immunol Lett. 2012;147:34-40 pubmed 出版商
Dangerfield E, Cheng J, Knight D, Weinkove R, Dunbar P, Hermans I, et al. Species-specific activity of glycolipid ligands for invariant NKT cells. Chembiochem. 2012;13:1349-56 pubmed 出版商
Noel G, DeKoter R, Wang Q, Hexley P, Ogle C. Optimization and application of a flow cytometric PU.1 assay for murine immune cells. J Immunol Methods. 2012;382:81-92 pubmed 出版商
Pollard K, Hultman P, Toomey C, Cauvi D, Hoffman H, Hamel J, et al. Definition of IFN-?-related pathways critical for chemically-induced systemic autoimmunity. J Autoimmun. 2012;39:323-31 pubmed 出版商
Berent Maoz B, Montecino Rodriguez E, Signer R, Dorshkind K. Fibroblast growth factor-7 partially reverses murine thymocyte progenitor aging by repression of Ink4a. Blood. 2012;119:5715-21 pubmed 出版商
Takahashi H, Kanno T, Nakayamada S, Hirahara K, Sciumè G, Muljo S, et al. TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells. Nat Immunol. 2012;13:587-95 pubmed 出版商
Ma J, Ding Y, Fang X, Wang R, Sun Z. Protein kinase C-? inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway. J Immunol. 2012;188:5337-47 pubmed 出版商
Köhler T, Reizis B, Johnson R, Weighardt H, Forster I. Influence of hypoxia-inducible factor 1? on dendritic cell differentiation and migration. Eur J Immunol. 2012;42:1226-36 pubmed 出版商
Silberman D, Bucknum A, Bartlett T, Composto G, Kozlowski M, Walker A, et al. CD28 ligation increases macrophage suppression of T-cell proliferation. Cell Mol Immunol. 2012;9:341-9 pubmed 出版商
Bönner F, Borg N, Burghoff S, Schrader J. Resident cardiac immune cells and expression of the ectonucleotidase enzymes CD39 and CD73 after ischemic injury. PLoS ONE. 2012;7:e34730 pubmed 出版商
Shaabani N, Honke N, Lang P, Gorg B, Proksch P, Gailus N, et al. Tunicamycin inhibits diabetes. Cell Physiol Biochem. 2012;29:595-602 pubmed 出版商
Kasahara D, Kim H, Williams A, Verbout N, Tran J, Si H, et al. Pulmonary inflammation induced by subacute ozone is augmented in adiponectin-deficient mice: role of IL-17A. J Immunol. 2012;188:4558-67 pubmed 出版商
Hacker H, Chi L, Rehg J, Redecke V. NIK prevents the development of hypereosinophilic syndrome-like disease in mice independent of IKK? activation. J Immunol. 2012;188:4602-10 pubmed 出版商
Iwata Y, Boström E, Menke J, Rabacal W, Morel L, Wada T, et al. Aberrant macrophages mediate defective kidney repair that triggers nephritis in lupus-susceptible mice. J Immunol. 2012;188:4568-80 pubmed 出版商
Van V, Raymond M, Baba N, Rubio M, Wakahara K, Susin S, et al. CD47(high) expression on CD4 effectors identifies functional long-lived memory T cell progenitors. J Immunol. 2012;188:4249-55 pubmed 出版商
Wensveen F, Unger P, Kragten N, Derks I, ten Brinke A, Arens R, et al. CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load. J Immunol. 2012;188:4256-67 pubmed 出版商
DRUTMAN S, Kendall J, Trombetta E. Inflammatory spleen monocytes can upregulate CD11c expression without converting into dendritic cells. J Immunol. 2012;188:3603-10 pubmed 出版商
Miyahara Y, Khattar M, Schroder P, Mierzejewska B, Deng R, Han R, et al. Anti-TCR? mAb induces long-term allograft survival by reducing antigen-reactive T cells and sparing regulatory T cells. Am J Transplant. 2012;12:1409-18 pubmed 出版商
Auderset F, Schuster S, Coutaz M, Koch U, Desgranges F, Merck E, et al. Redundant Notch1 and Notch2 signaling is necessary for IFN? secretion by T helper 1 cells during infection with Leishmania major. PLoS Pathog. 2012;8:e1002560 pubmed 出版商
Loebbermann J, Schnoeller C, Thornton H, Durant L, Sweeney N, Schuijs M, et al. IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice. PLoS ONE. 2012;7:e32371 pubmed 出版商
Zhao Y, French A. Two-compartment model of NK cell proliferation: insights from population response to IL-15 stimulation. J Immunol. 2012;188:2981-90 pubmed 出版商
Procario M, Levine R, McCarthy M, Kim E, Zhu L, Chang C, et al. Susceptibility to acute mouse adenovirus type 1 respiratory infection and establishment of protective immunity in neonatal mice. J Virol. 2012;86:4194-203 pubmed 出版商
Yamaji O, Nagaishi T, Totsuka T, Onizawa M, Suzuki M, Tsuge N, et al. The development of colitogenic CD4(+) T cells is regulated by IL-7 in collaboration with NK cell function in a murine model of colitis. J Immunol. 2012;188:2524-36 pubmed 出版商
Aizman E, Mor A, Levy A, George J, Kloog Y. Ras inhibition by FTS attenuates brain tumor growth in mice by direct antitumor activity and enhanced reactivity of cytotoxic lymphocytes. Oncotarget. 2012;3:144-57 pubmed
Hafalla J, Claser C, Couper K, Grau G, Renia L, de Souza J, et al. The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathog. 2012;8:e1002504 pubmed 出版商
Rothbard J, Kurnellas M, Brownell S, Adams C, Su L, Axtell R, et al. Therapeutic effects of systemic administration of chaperone αB-crystallin associated with binding proinflammatory plasma proteins. J Biol Chem. 2012;287:9708-21 pubmed 出版商
Gu P, Gao J, D Souza C, Kowalczyk A, Chou K, Zhang L. Trogocytosis of CD80 and CD86 by induced regulatory T cells. Cell Mol Immunol. 2012;9:136-46 pubmed 出版商
Meinhardt K, Kroeger I, Abendroth A, Muller S, Mackensen A, Ullrich E. Influence of NK cell magnetic bead isolation methods on phenotype and function of murine NK cells. J Immunol Methods. 2012;378:1-10 pubmed 出版商
McNamee E, Masterson J, Jedlicka P, Collins C, Williams I, Rivera Nieves J. Ectopic lymphoid tissue alters the chemokine gradient, increases lymphocyte retention and exacerbates murine ileitis. Gut. 2013;62:53-62 pubmed 出版商
Tawara I, Sun Y, Liu C, Toubai T, Nieves E, Evers R, et al. Donor- but not host-derived interleukin-10 contributes to the regulation of experimental graft-versus-host disease. J Leukoc Biol. 2012;91:667-75 pubmed 出版商
Fotin Mleczek M, Zanzinger K, Heidenreich R, Lorenz C, Thess A, Duchardt K, et al. Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect. J Gene Med. 2012;14:428-39 pubmed 出版商
Yoshida H, Kimura A, Fukaya T, Sekiya T, Morita R, Shichita T, et al. Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation. Biochem Biophys Res Commun. 2012;418:234-40 pubmed 出版商
Tietze J, Wilkins D, Sckisel G, Bouchlaka M, Alderson K, Weiss J, et al. Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy. Blood. 2012;119:3073-83 pubmed 出版商
Goicochea M, Zapata J, Bryant J, Davis H, Salvato M, Lukashevich I. Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model. Vaccine. 2012;30:1445-52 pubmed 出版商
Engels B, Chervin A, Sant A, Kranz D, Schreiber H. Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity. Mol Ther. 2012;20:652-60 pubmed 出版商
Goldstein M, Kohrt H, Houot R, Varghese B, Lin J, Swanson E, et al. Adoptive cell therapy for lymphoma with CD4 T cells depleted of CD137-expressing regulatory T cells. Cancer Res. 2012;72:1239-47 pubmed 出版商
Tian L, De Hertogh G, Fedeli M, Staats K, Schonefeldt S, Humblet Baron S, et al. Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice. J Autoimmun. 2012;38:39-48 pubmed 出版商
Mukherjee S, Giamberardino C, Thomas J, Evans K, Goto H, Ledford J, et al. Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation. J Immunol. 2012;188:957-67 pubmed 出版商
Qin H, Suzuki K, Nakata M, Chikuma S, Izumi N, Huong L, et al. Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age. PLoS ONE. 2011;6:e29141 pubmed 出版商
Kanistanon D, Powell D, Hajjar A, Pelletier M, Cohen I, Way S, et al. Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses. Infect Immun. 2012;80:943-51 pubmed 出版商
Ioannou M, Alissafi T, Lazaridis I, Deraos G, Matsoukas J, Gravanis A, et al. Crucial role of granulocytic myeloid-derived suppressor cells in the regulation of central nervous system autoimmune disease. J Immunol. 2012;188:1136-46 pubmed 出版商
Ogino H, Nakamura K, Iwasa T, Ihara E, Akiho H, Motomura Y, et al. Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model. J Gastroenterol. 2012;47:366-76 pubmed 出版商
Kanzaki M, Wada J, Sugiyama K, Nakatsuka A, Teshigawara S, Murakami K, et al. Galectin-9 and T cell immunoglobulin mucin-3 pathway is a therapeutic target for type 1 diabetes. Endocrinology. 2012;153:612-20 pubmed 出版商
Gomez I, Tang J, Wilson C, Yan W, Heinecke J, Harlan J, et al. Metalloproteinase-mediated Shedding of Integrin ?2 promotes macrophage efflux from inflammatory sites. J Biol Chem. 2012;287:4581-9 pubmed 出版商
Semmrich M, Plantinga M, Svensson Frej M, Uronen Hansson H, Gustafsson T, Mowat A, et al. Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses. Mucosal Immunol. 2012;5:150-60 pubmed 出版商
Saito H, Yamamoto Y, Yamamoto H. Diabetes alters subsets of endothelial progenitor cells that reside in blood, bone marrow, and spleen. Am J Physiol Cell Physiol. 2012;302:C892-901 pubmed 出版商
Mitrovic M, Arapovic J, Jordan S, Fodil Cornu N, Ebert S, Vidal S, et al. The NK cell response to mouse cytomegalovirus infection affects the level and kinetics of the early CD8(+) T-cell response. J Virol. 2012;86:2165-75 pubmed 出版商
Levin M, Lidberg U, Jirholt P, Adiels M, Wramstedt A, Gustafsson K, et al. Evaluation of macrophage-specific promoters using lentiviral delivery in mice. Gene Ther. 2012;19:1041-7 pubmed 出版商
Kliche S, Worbs T, Wang X, Degen J, Patzak I, Meineke B, et al. CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules. Blood. 2012;119:777-85 pubmed 出版商
Aksoylar H, Lampe K, Barnes M, Plas D, Hoebe K. Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells. J Immunol. 2012;188:146-54 pubmed 出版商
Lin J, Stein E, Wong M, Kalpathy K, Su L, Utz P, et al. Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis. Clin Immunol. 2012;142:127-38 pubmed 出版商
Vaknin I, Kunis G, Miller O, Butovsky O, Bukshpan S, Beers D, et al. Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis. PLoS ONE. 2011;6:e26921 pubmed 出版商
Badeaux A, Yang Y, Cardenas K, Vemulapalli V, Chen K, Kusewitt D, et al. Loss of the methyl lysine effector protein PHF20 impacts the expression of genes regulated by the lysine acetyltransferase MOF. J Biol Chem. 2012;287:429-37 pubmed 出版商
Freeman S, Lei V, Dang Lawson M, Mizuno K, Roskelley C, Gold M. Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation. J Immunol. 2011;187:5887-900 pubmed 出版商
Pillai M, Collison L, Wang X, Finkelstein D, Rehg J, Boyd K, et al. The plasticity of regulatory T cell function. J Immunol. 2011;187:4987-97 pubmed 出版商
Lilla J, Chen C, Mukai K, Benbarak M, Franco C, Kalesnikoff J, et al. Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice. Blood. 2011;118:6930-8 pubmed 出版商
Kreisel D, Sugimoto S, Zhu J, Nava R, Li W, Okazaki M, et al. Emergency granulopoiesis promotes neutrophil-dendritic cell encounters that prevent mouse lung allograft acceptance. Blood. 2011;118:6172-82 pubmed 出版商
Sato Hayashizaki A, Ohtsuji M, Lin Q, Hou R, Ohtsuji N, Nishikawa K, et al. Presumptive role of 129 strain-derived Sle16 locus in rheumatoid arthritis in a new mouse model with Fc? receptor type IIb-deficient C57BL/6 genetic background. Arthritis Rheum. 2011;63:2930-8 pubmed 出版商
Moro H, Otero D, Tanabe Y, David M. T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival. PLoS ONE. 2011;6:e24972 pubmed 出版商
Mori T, Miyamoto T, Yoshida H, Asakawa M, Kawasumi M, Kobayashi T, et al. IL-1? and TNF?-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis. Int Immunol. 2011;23:701-12 pubmed 出版商
Ma J, Wang R, Fang X, Ding Y, Sun Z. Critical role of TCF-1 in repression of the IL-17 gene. PLoS ONE. 2011;6:e24768 pubmed 出版商
Ernst P, Erickson L, Loo W, Scott K, Wiznerowicz E, Brown C, et al. Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice. Am J Physiol Gastrointest Liver Physiol. 2012;302:G105-15 pubmed 出版商
Pasieka T, Collins L, O Connor M, Chen Y, Parker Z, Berwin B, et al. Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in ?ß? interferon receptor-deficient mice. PLoS ONE. 2011;6:e24018 pubmed 出版商
Mayol K, Biajoux V, Marvel J, Balabanian K, Walzer T. Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking. Blood. 2011;118:4863-71 pubmed 出版商
Noorbakhsh F, Ellestad K, Maingat F, Warren K, Han M, Steinman L, et al. Impaired neurosteroid synthesis in multiple sclerosis. Brain. 2011;134:2703-21 pubmed 出版商
Housley W, Adams C, Vang A, Brocke S, Nichols F, Lacombe M, et al. Peroxisome proliferator-activated receptor gamma is required for CD4+ T cell-mediated lymphopenia-associated autoimmunity. J Immunol. 2011;187:4161-9 pubmed 出版商
Ishida W, Fukuda K, Sakamoto S, Koyama N, Koyanagi A, Yagita H, et al. Regulation of experimental autoimmune uveoretinitis by anti-delta-like ligand 4 monoclonal antibody. Invest Ophthalmol Vis Sci. 2011;52:8224-30 pubmed 出版商
Ohue R, Hashimoto K, Nakamoto M, Furukawa Y, Masuda T, Kitabatake N, et al. Bacterial heat shock protein 60, GroEL, can induce the conversion of naïve T cells into a CD4 CD25(+) Foxp3-expressing phenotype. J Innate Immun. 2011;3:605-13 pubmed 出版商
Garchow B, Bartulos Encinas O, Leung Y, Tsao P, Eisenberg R, Caricchio R, et al. Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice. EMBO Mol Med. 2011;3:605-15 pubmed 出版商
Jessen B, Maul Pavicic A, Ufheil H, Vraetz T, Enders A, Lehmberg K, et al. Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome. Blood. 2011;118:4620-9 pubmed 出版商
Bravo Nuevo A, O Donnell R, Rosendahl A, Chung J, Benjamin L, Odaka C. RhoB deficiency in thymic medullary epithelium leads to early thymic atrophy. Int Immunol. 2011;23:593-600 pubmed 出版商
Lee I, van den Elzen P, Tan R, Priatel J. NKT cells are required for complete Freund's adjuvant-mediated protection from autoimmune diabetes. J Immunol. 2011;187:2898-904 pubmed 出版商
Gaspal F, Withers D, Saini M, Bekiaris V, McConnell F, White A, et al. Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice. J Exp Med. 2011;208:1579-84 pubmed 出版商
Muller Y, Golshayan D, Ehirchiou D, Wyss J, Giovannoni L, Meier R, et al. Immunosuppressive effects of streptozotocin-induced diabetes result in absolute lymphopenia and a relative increase of T regulatory cells. Diabetes. 2011;60:2331-40 pubmed 出版商
Tani ichi S, Satake M, Ikuta K. The pre-TCR signal induces transcriptional silencing of the TCR? locus by reducing the recruitment of STAT5 and Runx to transcriptional enhancers. Int Immunol. 2011;23:553-63 pubmed 出版商
Penaranda C, Tang Q, Bluestone J. Anti-CD3 therapy promotes tolerance by selectively depleting pathogenic cells while preserving regulatory T cells. J Immunol. 2011;187:2015-22 pubmed 出版商
Barlow J, Flynn R, Ballantyne S, McKenzie A. Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity. Clin Exp Allergy. 2011;41:1447-55 pubmed 出版商
Narayan S, Kolly L, So A, Busso N. Increased interleukin-10 production by ASC-deficient CD4+ T cells impairs bystander T-cell proliferation. Immunology. 2011;134:33-40 pubmed 出版商
Gonzalez Martin A, Gomez L, Lustgarten J, Mira E, Manes S. Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4(+) and CD8(+) T cells. Cancer Res. 2011;71:5455-66 pubmed 出版商
Bosmann M, Russkamp N, Patel V, Zetoune F, Sarma J, Ward P. The outcome of polymicrobial sepsis is independent of T and B cells. Shock. 2011;36:396-401 pubmed 出版商
Muniz L, Pacer M, Lira S, Furtado G. A critical role for dendritic cells in the formation of lymphatic vessels within tertiary lymphoid structures. J Immunol. 2011;187:828-34 pubmed 出版商
Qian B, Li J, Zhang H, Kitamura T, Zhang J, Campion L, et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature. 2011;475:222-5 pubmed 出版商
Knosp C, Carroll H, Elliott J, Saunders S, Nel H, Amu S, et al. SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses. J Exp Med. 2011;208:1523-31 pubmed 出版商
Yu H, Qin H, He F, Wang L, Fu W, Liu D, et al. Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling. Hepatology. 2011;54:979-88 pubmed 出版商
Arias K, Chu D, Flader K, Botelho F, Walker T, Arias N, et al. Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice. J Allergy Clin Immunol. 2011;127:1552-61.e1 pubmed 出版商
Burke S, Barrette V, Carter A, Gravel J, Adams M, Croy B. Cardiovascular adaptations of pregnancy in T and B cell-deficient mice. Biol Reprod. 2011;85:605-14 pubmed 出版商
Ichiyama K, Sekiya T, Inoue N, Tamiya T, Kashiwagi I, Kimura A, et al. Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-? is mediated by suppression of eomesodermin. Immunity. 2011;34:741-54 pubmed 出版商
Song L, Lee C, Schindler C. Deletion of the murine scavenger receptor CD68. J Lipid Res. 2011;52:1542-50 pubmed 出版商
Weinger J, Brosnan C, Loudig O, Goldberg M, Macian F, Arnett H, et al. Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis. J Neuroinflammation. 2011;8:49 pubmed 出版商
Meng J, Greenlee A, Taub C, Braun R. Sertoli cell-specific deletion of the androgen receptor compromises testicular immune privilege in mice. Biol Reprod. 2011;85:254-60 pubmed 出版商
Tosiek M, Gruber A, Bader S, Mauel S, Hoymann H, Prettin S, et al. CD4+CD25+Foxp3+ regulatory T cells are dispensable for controlling CD8+ T cell-mediated lung inflammation. J Immunol. 2011;186:6106-18 pubmed 出版商
Pyzik M, Charbonneau B, Gendron Pontbriand E, Babic M, Krmpotic A, Jonjic S, et al. Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains. J Exp Med. 2011;208:1105-17 pubmed 出版商
Prajeeth C, Haeberlein S, Sebald H, Schleicher U, Bogdan C. Leishmania-infected macrophages are targets of NK cell-derived cytokines but not of NK cell cytotoxicity. Infect Immun. 2011;79:2699-708 pubmed 出版商
Haworth O, Cernadas M, Levy B. NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation. J Immunol. 2011;186:6129-35 pubmed 出版商
Lorenzo L, Chen H, Shatynski K, Clark S, Yuan R, Harrison D, et al. Defective hematopoietic stem cell and lymphoid progenitor development in the Ts65Dn mouse model of Down syndrome: potential role of oxidative stress. Antioxid Redox Signal. 2011;15:2083-94 pubmed 出版商
Nishikado H, Mukai K, Kawano Y, Minegishi Y, Karasuyama H. NK cell-depleting anti-asialo GM1 antibody exhibits a lethal off-target effect on basophils in vivo. J Immunol. 2011;186:5766-71 pubmed 出版商
Kitajima M, Lee H, Nakayama T, Ziegler S. TSLP enhances the function of helper type 2 cells. Eur J Immunol. 2011;41:1862-71 pubmed 出版商
Davidson S, Kaiko G, Loh Z, Lalwani A, Zhang V, Spann K, et al. Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway. J Immunol. 2011;186:5938-48 pubmed 出版商
Okamoto T, Saito T, Tabata Y, Uemoto S. Immunological tolerance in a mouse model of immune-mediated liver injury induced by 16,16 dimethyl PGE2 and PGE2-containing nanoscale hydrogels. Biomaterials. 2011;32:4925-35 pubmed 出版商
Huang F, Barnes P, Feng Y, Donis R, Chroneos Z, Idell S, et al. GM-CSF in the lung protects against lethal influenza infection. Am J Respir Crit Care Med. 2011;184:259-68 pubmed 出版商
Goudy K, Johnson M, Garland A, Li C, Samulski R, Wang B, et al. Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62Llo FoxP3+ CD4+ T cells with limited suppressor activity. Eur J Immunol. 2011;41:1480-1490 pubmed 出版商
Kim H, Jung B, Lee J, Pyo K, Kim T, Choi B, et al. CD8 T-cell activation in mice injected with a plasmid DNA vaccine encoding AMA-1 of the reemerging Korean Plasmodium vivax. Korean J Parasitol. 2011;49:85-90 pubmed 出版商
Shimizu K, Asakura M, Fujii S. Prolonged antitumor NK cell reactivity elicited by CXCL10-expressing dendritic cells licensed by CD40L+ CD4+ memory T cells. J Immunol. 2011;186:5927-37 pubmed 出版商
Erhardt A, Wegscheid C, Claass B, Carambia A, Herkel J, Mittrücker H, et al. CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis. J Immunol. 2011;186:5284-93 pubmed 出版商
Link A, Hardie D, Favre S, Britschgi M, Adams D, Sixt M, et al. Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans. Am J Pathol. 2011;178:1662-75 pubmed 出版商
Sakamoto N, Rosenberg A. Apolipoprotein B binding domains: evidence that they are cell-penetrating peptides that efficiently deliver antigenic peptide for cross-presentation of cytotoxic T cells. J Immunol. 2011;186:5004-11 pubmed 出版商
Shimo Y, Yanai H, Ohshima D, Qin J, Motegi H, Maruyama Y, et al. TRAF6 directs commitment to regulatory T cells in thymocytes. Genes Cells. 2011;16:437-47 pubmed 出版商
Wang L, Rubinstein R, Lines J, Wasiuk A, Ahonen C, Guo Y, et al. VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses. J Exp Med. 2011;208:577-92 pubmed 出版商
Trandem K, Zhao J, Fleming E, Perlman S. Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis. J Immunol. 2011;186:3642-52 pubmed 出版商
Christopher M, Rao M, Liu F, Woloszynek J, Link D. Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice. J Exp Med. 2011;208:251-60 pubmed 出版商
Zhang T, Sentman C. Cancer immunotherapy using a bispecific NK receptor fusion protein that engages both T cells and tumor cells. Cancer Res. 2011;71:2066-76 pubmed 出版商
Kaplan I, Morisot S, Heiser D, Cheng W, Kim M, Civin C. Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence. J Immunol. 2011;186:2826-34 pubmed 出版商
Guarda G, Zenger M, Yazdi A, Schroder K, Ferrero I, Menu P, et al. Differential expression of NLRP3 among hematopoietic cells. J Immunol. 2011;186:2529-34 pubmed 出版商
Islam S, Chang D, Colvin R, Byrne M, McCully M, Moser B, et al. Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat Immunol. 2011;12:167-77 pubmed 出版商
Welch J, Klco J, Varghese N, Nagarajan R, Ley T. Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice. Blood. 2011;117:2460-8 pubmed 出版商
Yeo C, Fearon D. T-bet-mediated differentiation of the activated CD8+ T cell. Eur J Immunol. 2011;41:60-6 pubmed 出版商
Tachibana M, Tenno M, Tezuka C, Sugiyama M, Yoshida H, Taniuchi I. Runx1/Cbf?2 complexes are required for lymphoid tissue inducer cell differentiation at two developmental stages. J Immunol. 2011;186:1450-7 pubmed 出版商
Chow Y, Zhu X, Liu L, Schwartz B, Huang X, Harlan J, et al. Role of Cdk4 in lymphocyte function and allergen response. Cell Cycle. 2010;9:4922-30 pubmed
Hebenstreit D, Gu M, Haider S, Turner D, Lio P, Teichmann S. EpiChIP: gene-by-gene quantification of epigenetic modification levels. Nucleic Acids Res. 2011;39:e27 pubmed 出版商
Machida Y, Kitamoto K, Izumi Y, Shiota M, Uchida J, Kira Y, et al. Renal fibrosis in murine obstructive nephropathy is attenuated by depletion of monocyte lineage, not dendritic cells. J Pharmacol Sci. 2010;114:464-73 pubmed
Matsunaga Y, Inoue H, Fukuyama S, Yoshida H, Moriwaki A, Matsumoto T, et al. Effects of a Janus kinase inhibitor, pyridone 6, on airway responses in a murine model of asthma. Biochem Biophys Res Commun. 2011;404:261-7 pubmed 出版商
O Connor R, Leech M, Suffner J, Hämmerling G, Anderton S. Myelin-reactive, TGF-?-induced regulatory T cells can be programmed to develop Th1-like effector function but remain less proinflammatory than myelin-reactive Th1 effectors and can suppress pathogenic T cell clonal expansion in vivo. J Immunol. 2010;185:7235-43 pubmed 出版商
Carlson M, Fulton L, Coghill J, West M, Burgents J, Wan Y, et al. L-selectin is dispensable for T regulatory cell function postallogeneic bone marrow transplantation. Am J Transplant. 2010;10:2596-603 pubmed 出版商
Schneider D, Palmer J, Tulley J, Kovacs E, Gamelli R, Faunce D. Prevention of NKT cell activation accelerates cutaneous wound closure and alters local inflammatory signals. J Surg Res. 2011;171:361-73 pubmed 出版商
Stumhofer J, Tait E, Quinn W, Hosken N, Spudy B, Goenka R, et al. A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat Immunol. 2010;11:1119-26 pubmed 出版商
Buhtoiarov I, Sondel P, Wigginton J, Buhtoiarova T, Yanke E, Mahvi D, et al. Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages. Immunology. 2011;132:226-39 pubmed 出版商
Munroe M, Businga T, Kline J, Bishop G. Anti-inflammatory effects of the neurotransmitter agonist Honokiol in a mouse model of allergic asthma. J Immunol. 2010;185:5586-97 pubmed 出版商
Small S, Keerthivasan G, Huang Z, Gurbuxani S, Crispino J. Overexpression of survivin initiates hematologic malignancies in vivo. Leukemia. 2010;24:1920-6 pubmed 出版商
Gossens K, Naus S, Hollander G, Ziltener H. Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity. PLoS ONE. 2010;5:e12766 pubmed 出版商
Brown M, Fintushel S, Lee M, Jennrich S, Geherin S, Hay J, et al. Chemoattractant receptors and lymphocyte egress from extralymphoid tissue: changing requirements during the course of inflammation. J Immunol. 2010;185:4873-82 pubmed 出版商
Kamphorst A, Guermonprez P, Dudziak D, Nussenzweig M. Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes. J Immunol. 2010;185:3426-35 pubmed 出版商
Sonn C, Yu Y, Hong Y, Shim Y, Bluestone J, Min B, et al. Clusterin synergizes with IL-2 for the expansion and IFN-? production of natural killer cells. J Leukoc Biol. 2010;88:955-63 pubmed 出版商
Freire T, Zhang X, Deriaud E, Ganneau C, Vichier Guerre S, Azria E, et al. Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant. Blood. 2010;116:3526-36 pubmed 出版商
Gomez C, Karavitis J, Palmer J, Faunce D, Ramirez L, Nomellini V, et al. Interleukin-6 contributes to age-related alteration of cytokine production by macrophages. Mediators Inflamm. 2010;2010:475139 pubmed 出版商
Lages C, Lewkowich I, Sproles A, Wills Karp M, Chougnet C. Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/?PD-L1 pathway. Aging Cell. 2010;9:785-98 pubmed 出版商
DRUTMAN S, Trombetta E. Dendritic cells continue to capture and present antigens after maturation in vivo. J Immunol. 2010;185:2140-6 pubmed 出版商
Huber S, Hoffmann R, Muskens F, Voehringer D. Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2. Blood. 2010;116:3311-20 pubmed 出版商
Stevenson H, Estes M, Thirumalapura N, Walker D, Ismail N. Natural killer cells promote tissue injury and systemic inflammatory responses during fatal Ehrlichia-induced toxic shock-like syndrome. Am J Pathol. 2010;177:766-76 pubmed 出版商
Polansky J, Schreiber L, Thelemann C, Ludwig L, Krüger M, Baumgrass R, et al. Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells. J Mol Med (Berl). 2010;88:1029-40 pubmed 出版商
Carr E, Kelman A, Wu G, Gopaul R, Senkevitch E, Aghvanyan A, et al. Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation. J Immunol. 2010;185:1037-44 pubmed 出版商
Anraku M, Tagawa T, Wu L, Yun Z, Keshavjee S, Zhang L, et al. Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignant mesothelioma. J Immunol. 2010;185:956-66 pubmed 出版商
Teng L, Liu L, Su Y, Yuan X, Li J, Fu Q, et al. Suppression of alloimmunity in mice by regulatory T cells converted with conditioned media. J Surg Res. 2011;171:797-806 pubmed 出版商
Helms M, Prescher J, Cao Y, Schaffert S, Contag C. IL-12 enhances efficacy and shortens enrichment time in cytokine-induced killer cell immunotherapy. Cancer Immunol Immunother. 2010;59:1325-34 pubmed 出版商
Teige A, Bockermann R, Hasan M, Olofsson K, Liu Y, Issazadeh Navikas S. CD1d-dependent NKT cells play a protective role in acute and chronic arthritis models by ameliorating antigen-specific Th1 responses. J Immunol. 2010;185:345-56 pubmed 出版商
Bhadra R, Guan H, Khan I. Absence of both IL-7 and IL-15 severely impairs the development of CD8 T cell response against Toxoplasma gondii. PLoS ONE. 2010;5:e10842 pubmed 出版商
Redford P, Boonstra A, Read S, Pitt J, Graham C, Stavropoulos E, et al. Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung. Eur J Immunol. 2010;40:2200-10 pubmed 出版商
Cha H, Chang S, Chang J, Kim J, Yang J, Kim C, et al. Downregulation of Th17 cells in the small intestine by disruption of gut flora in the absence of retinoic acid. J Immunol. 2010;184:6799-806 pubmed 出版商
Composto G, Gonzalez D, Bucknum A, Silberman D, Taylor J, Kozlowski M, et al. Peritoneal T lymphocyte regulation by macrophages. Immunobiology. 2011;216:256-64 pubmed 出版商
Mitsui J, Nishikawa H, Muraoka D, Wang L, Noguchi T, Sato E, et al. Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals. Clin Cancer Res. 2010;16:2781-91 pubmed 出版商
Muller Y, Mai G, Morel P, Serre Beinier V, Gonelle Gispert C, Yung G, et al. Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation. PLoS ONE. 2010;5:e10352 pubmed 出版商
Tomihara K, Guo M, Shin T, Sun X, Ludwig S, Brumlik M, et al. Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells. J Immunol. 2010;184:6151-60 pubmed 出版商
Dohse M, Scharenberg C, Shukla S, Robey R, Volkmann T, Deeken J, et al. Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib. Drug Metab Dispos. 2010;38:1371-80 pubmed 出版商
Fang X, Du P, Liu Y, Tang J. Efficient isolation of mouse liver NKT cells by perfusion. PLoS ONE. 2010;5:e10288 pubmed 出版商
Xie X, Stadnisky M, Coats E, Ahmed Rahim M, Lundgren A, Xu W, et al. MHC class I D(k) expression in hematopoietic and nonhematopoietic cells confers natural killer cell resistance to murine cytomegalovirus. Proc Natl Acad Sci U S A. 2010;107:8754-9 pubmed 出版商
Lehnertz B, Northrop J, Antignano F, Burrows K, Hadidi S, Mullaly S, et al. Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function. J Exp Med. 2010;207:915-22 pubmed 出版商
Kim Y, Kim K, Shevach E. Simvastatin induces Foxp3+ T regulatory cells by modulation of transforming growth factor-beta signal transduction. Immunology. 2010;130:484-93 pubmed 出版商
Ip P, Liao F. Resistance to dengue virus infection in mice is potentiated by CXCL10 and is independent of CXCL10-mediated leukocyte recruitment. J Immunol. 2010;184:5705-14 pubmed 出版商
Farquhar C, Paterson A, Cobbold S, Garcia Rueda H, Fairchild P, Yates S, et al. Tolerogenicity is not an absolute property of a dendritic cell. Eur J Immunol. 2010;40:1728-37 pubmed 出版商
Ritprajak P, Hashiguchi M, Tsushima F, Chalermsarp N, Azuma M. Keratinocyte-associated B7-H1 directly regulates cutaneous effector CD8+ T cell responses. J Immunol. 2010;184:4918-25 pubmed 出版商
Yang L, Cui H, Wang Z, Zhang B, Ding J, Liu L, et al. Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation. Am J Pathol. 2010;176:2646-57 pubmed 出版商
Wilson D, Grotenbreg G, Liu K, Zhao Y, Frickel E, Gubbels M, et al. Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells. PLoS Pathog. 2010;6:e1000815 pubmed 出版商
Dubrot J, Palazon A, Alfaro C, Azpilikueta A, Ochoa M, Rouzaut A, et al. Intratumoral injection of interferon-? and systemic delivery of agonist anti-CD137 monoclonal antibodies synergize for immunotherapy. Int J Cancer. 2011;128:105-18 pubmed 出版商
Barral P, Polzella P, Bruckbauer A, Van Rooijen N, Besra G, Cerundolo V, et al. CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes. Nat Immunol. 2010;11:303-12 pubmed 出版商
Motz G, Eppert B, Wortham B, Amos Kroohs R, Flury J, Wesselkamper S, et al. Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease. J Immunol. 2010;184:4460-9 pubmed 出版商
Giuriato S, Foisseau M, Dejean E, Felsher D, Al Saati T, Demur C, et al. Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemia. Blood. 2010;115:4061-70 pubmed 出版商
Hirata Y, Hamanaka S, Onodera M. Transactivation of the dopamine receptor 3 gene by a single provirus integration results in development of B-cell lymphoma in transgenic mice generated from retrovirally transduced embryonic stem cells. Blood. 2010;115:3930-8 pubmed 出版商
Reijmers R, Vondenhoff M, Roozendaal R, Kuil A, Li J, Spaargaren M, et al. Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase. J Immunol. 2010;184:3656-64 pubmed 出版商
Naus S, Blanchet M, Gossens K, Zaph C, Bartsch J, McNagny K, et al. The metalloprotease-disintegrin ADAM8 is essential for the development of experimental asthma. Am J Respir Crit Care Med. 2010;181:1318-28 pubmed 出版商
Jacobs S, Michalek R, Rathmell J. IL-7 is essential for homeostatic control of T cell metabolism in vivo. J Immunol. 2010;184:3461-9 pubmed 出版商
Berger M, Krebs P, Crozat K, Li X, Croker B, Siggs O, et al. An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence. Nat Immunol. 2010;11:335-43 pubmed 出版商
Voronov E, Dotan S, Gayvoronsky L, White R, Cohen I, Krelin Y, et al. IL-1-induced inflammation promotes development of leishmaniasis in susceptible BALB/c mice. Int Immunol. 2010;22:245-57 pubmed 出版商
Wilson M, Madala S, Ramalingam T, Gochuico B, Rosas I, Cheever A, et al. Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent. J Exp Med. 2010;207:535-52 pubmed 出版商
Eppert B, Motz G, Wortham B, Flury J, Borchers M. CCR7 deficiency leads to leukocyte activation and increased clearance in response to pulmonary Pseudomonas aeruginosa infection. Infect Immun. 2010;78:2099-107 pubmed 出版商
Henry T, Kirimanjeswara G, Ruby T, Jones J, Peng K, Perret M, et al. Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections. J Immunol. 2010;184:3755-67 pubmed 出版商
Paschalidis N, Huggins A, Rowbotham N, Furmanski A, Crompton T, Flower R, et al. Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection. Cell Cycle. 2010;9:784-93 pubmed
Létourneau S, van Leeuwen E, Krieg C, Martin C, Pantaleo G, Sprent J, et al. IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25. Proc Natl Acad Sci U S A. 2010;107:2171-6 pubmed 出版商
Cavassani K, Carson W, Moreira A, Wen H, Schaller M, Ishii M, et al. The post sepsis-induced expansion and enhanced function of regulatory T cells create an environment to potentiate tumor growth. Blood. 2010;115:4403-11 pubmed 出版商
DeNucci C, Pagán A, Mitchell J, Shimizu Y. Control of alpha4beta7 integrin expression and CD4 T cell homing by the beta1 integrin subunit. J Immunol. 2010;184:2458-67 pubmed 出版商
Xu X, Wen X, Chi Y, He L, Zhou S, Wang X, et al. Activation-induced T helper cell death contributes to Th1/Th2 polarization following murine Schistosoma japonicum infection. J Biomed Biotechnol. 2010;2010:202397 pubmed 出版商
Strissel K, DeFuria J, Shaul M, Bennett G, Greenberg A, Obin M. T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice. Obesity (Silver Spring). 2010;18:1918-25 pubmed 出版商
Karamitros D, Kotantaki P, Lygerou Z, Veiga Fernandes H, Pachnis V, Kioussis D, et al. Differential geminin requirement for proliferation of thymocytes and mature T cells. J Immunol. 2010;184:2432-41 pubmed 出版商
Michaelis K, Wallbrecht K, Kerstan A, Beyersdorf N, Williams C, Kerkau T, et al. Modulating T cell functions does not alleviate chronic inflammatory skin lesions in K5.TGF beta 1 transgenic mice. Exp Dermatol. 2010;19:406-15 pubmed 出版商
Chen L, Lin S, Amin S, Overbergh L, Maggiolino G, Chan L. VCAM-1 blockade delays disease onset, reduces disease severity and inflammatory cells in an atopic dermatitis model. Immunol Cell Biol. 2010;88:334-42 pubmed 出版商
Wilson A, Murphy G, Hamakawa H, Kwok L, Srinivasan S, Hovav A, et al. Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages. J Clin Invest. 2010;120:379-89 pubmed 出版商
Sanos S, Diefenbach A. Isolation of NK cells and NK-like cells from the intestinal lamina propria. Methods Mol Biol. 2010;612:505-17 pubmed 出版商
Croy B, Zhang J, Tayade C, Colucci F, Yadi H, Yamada A. Analysis of uterine natural killer cells in mice. Methods Mol Biol. 2010;612:465-503 pubmed 出版商
Lucas M, Vonarbourg C, Aichele P, Diefenbach A. Studying NK cell/dendritic cell interactions. Methods Mol Biol. 2010;612:97-126 pubmed 出版商
Hayakawa Y, Andrews D, Smyth M. Subset analysis of human and mouse mature NK cells. Methods Mol Biol. 2010;612:27-38 pubmed 出版商
Liu C, Wang Q, Liu F, Li H, Zhu F, Wang X, et al. The allogeneic but not syngeneic dendritic cells effectively generated regulatory T cells from total CD4+ population without exogenous cytokines. Scand J Immunol. 2010;71:12-9 pubmed 出版商
Singh N, Yamamoto M, Takami M, Seki Y, Takezaki M, Mellor A, et al. CD4(+)CD25(+) regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis. J Immunol. 2010;184:94-104 pubmed 出版商
Ohno T, Oboki K, Kajiwara N, Morii E, Aozasa K, Flavell R, et al. Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. J Immunol. 2009;183:7890-7 pubmed 出版商
Farrand K, Dickgreber N, Stoitzner P, Ronchese F, Petersen T, Hermans I. Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigens. J Immunol. 2009;183:7732-42 pubmed 出版商
Sauer K, Huang Y, Lin H, Sandberg M, Mayr G. Phosphoinositide and inositol phosphate analysis in lymphocyte activation. Curr Protoc Immunol. 2009;Chapter 11:Unit11.1 pubmed 出版商
Søndergaard H, Coquet J, Uldrich A, McLaughlin N, Godfrey D, Sivakumar P, et al. Endogenous IL-21 restricts CD8+ T cell expansion and is not required for tumor immunity. J Immunol. 2009;183:7326-36 pubmed 出版商
Bedoret D, Wallemacq H, Marichal T, Desmet C, Quesada Calvo F, Henry E, et al. Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. J Clin Invest. 2009;119:3723-38 pubmed 出版商
Kitamoto K, Machida Y, Uchida J, Izumi Y, Shiota M, Nakao T, et al. Effects of liposome clodronate on renal leukocyte populations and renal fibrosis in murine obstructive nephropathy. J Pharmacol Sci. 2009;111:285-92 pubmed
Beishuizen C, Kragten N, Boon L, Nolte M, van Lier R, van Gisbergen K. Chronic CD70-driven costimulation impairs IgG responses by instructing T cells to inhibit germinal center B cell formation through FasL-Fas interactions. J Immunol. 2009;183:6442-51 pubmed 出版商
Graham K, Zabel B, Loghavi S, Zuniga L, Ho P, Sobel R, et al. Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease. J Immunol. 2009;183:6717-23 pubmed 出版商
Cao X, Leonard K, Collins L, Cai S, Mayer J, Payton J, et al. Interleukin 12 stimulates IFN-gamma-mediated inhibition of tumor-induced regulatory T-cell proliferation and enhances tumor clearance. Cancer Res. 2009;69:8700-9 pubmed 出版商
Vazquez B, Laguna T, Carabana J, Krangel M, Lauzurica P. CD69 gene is differentially regulated in T and B cells by evolutionarily conserved promoter-distal elements. J Immunol. 2009;183:6513-21 pubmed 出版商
Lahl K, Mayer C, Bopp T, Huehn J, Loddenkemper C, Eberl G, et al. Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice. J Immunol. 2009;183:5662-72 pubmed 出版商
Vanden Bush T, Buchta C, Claudio J, Bishop G. Cutting Edge: Importance of IL-6 and cooperation between innate and adaptive immune receptors in cellular vaccination with B lymphocytes. J Immunol. 2009;183:4833-7 pubmed 出版商
Withers D, Jaensson E, Gaspal F, McConnell F, Eksteen B, Anderson G, et al. The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals. J Immunol. 2009;183:5079-84 pubmed 出版商
Scarlett U, Cubillos Ruiz J, Nesbeth Y, Martinez D, Engle X, Gewirtz A, et al. In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells. Cancer Res. 2009;69:7329-37 pubmed 出版商
Imada M, Masuda K, Satoh R, Ito Y, Goto Y, Matsuoka T, et al. Ectopically expressed PIR-B on T cells constitutively binds to MHC class I and attenuates T helper type 1 responses. Int Immunol. 2009;21:1151-61 pubmed 出版商
Olson J, Zeiser R, Beilhack A, Goldman J, Negrin R. Tissue-specific homing and expansion of donor NK cells in allogeneic bone marrow transplantation. J Immunol. 2009;183:3219-28 pubmed 出版商
Fu G, Gascoigne N. Multiplexed labeling of samples with cell tracking dyes facilitates rapid and accurate internally controlled calcium flux measurement by flow cytometry. J Immunol Methods. 2009;350:194-9 pubmed 出版商
Watanabe K, Carter J, Neely Burnam M, Colley D. Relative imbalance between T regulatory cells and activated T cells in mice with differential morbidity in chronic Schistosoma mansoni infections. Parasite Immunol. 2009;31:440-6 pubmed 出版商
Piconese S, Gri G, Tripodo C, Musio S, Gorzanelli A, Frossi B, et al. Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation. Blood. 2009;114:2639-48 pubmed 出版商
Schmutz S, Bosco N, Chappaz S, Boyman O, Acha Orbea H, Ceredig R, et al. Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells. J Immunol. 2009;183:2217-21 pubmed 出版商
Tang L, Yang J, Liu W, Tang X, Chen J, Zhao D, et al. Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response. Gastroenterology. 2009;137:1498-508.e1-5 pubmed 出版商
Gatzka M, Newton R, Walsh C. Altered thymic selection and increased autoimmunity caused by ectopic expression of DRAK2 during T cell development. J Immunol. 2009;183:285-97 pubmed 出版商
von Vietinghoff S, Ley K. IL-17A controls IL-17F production and maintains blood neutrophil counts in mice. J Immunol. 2009;183:865-73 pubmed 出版商
Shang L, Thirunarayanan N, Viejo Borbolla A, Martin A, Bogunovic M, Marchesi F, et al. Expression of the chemokine binding protein M3 promotes marked changes in the accumulation of specific leukocytes subsets within the intestine. Gastroenterology. 2009;137:1006-18, 1018.e1-3 pubmed 出版商
Vinay D, Kim C, Choi B, Kwon B. Origins and functional basis of regulatory CD11c+CD8+ T cells. Eur J Immunol. 2009;39:1552-63 pubmed 出版商
van Olffen R, Koning N, van Gisbergen K, Wensveen F, Hoek R, Boon L, et al. GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo. J Immunol. 2009;182:7490-500 pubmed 出版商
Astrakhan A, Ochs H, Rawlings D. Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells. J Immunol. 2009;182:7370-80 pubmed 出版商
He F, Chen Z, Xu S, Cai M, Wu M, Li H, et al. Increased CD4+CD25+Foxp3+ regulatory T cells in tolerance induced by portal venous injection. Surgery. 2009;145:663-74 pubmed 出版商
Hart K, Bak S, Alonso A, Berwin B. Phenotypic and functional delineation of murine CX(3)CR1 monocyte-derived cells in ovarian cancer. Neoplasia. 2009;11:564-73, 1 p following 573 pubmed
Niwa H, Satoh T, Matsushima Y, Hosoya K, Saeki K, Niki T, et al. Stable form of galectin-9, a Tim-3 ligand, inhibits contact hypersensitivity and psoriatic reactions: a potent therapeutic tool for Th1- and/or Th17-mediated skin inflammation. Clin Immunol. 2009;132:184-94 pubmed 出版商
Alves B, Leong J, Tamang D, Elliott V, Edelnant J, Redelman D, et al. Pancreatic lipase-related protein 2 (PLRP2) induction by IL-4 in cytotoxic T lymphocytes (CTLs) and reevaluation of the negative effects of its gene ablation on cytotoxicity. J Leukoc Biol. 2009;86:701-12 pubmed 出版商
Shiokawa A, Tanabe K, Tsuji N, Sato R, Hachimura S. IL-10 and IL-27 producing dendritic cells capable of enhancing IL-10 production of T cells are induced in oral tolerance. Immunol Lett. 2009;125:7-14 pubmed 出版商
Cridland S, Keys J, Papathanasiou P, Perkins A. Indian hedgehog supports definitive erythropoiesis. Blood Cells Mol Dis. 2009;43:149-55 pubmed 出版商
Cai S, Fehniger T, Cao X, Mayer J, Brune J, French A, et al. Differential expression of granzyme B and C in murine cytotoxic lymphocytes. J Immunol. 2009;182:6287-97 pubmed 出版商
Lin J, Lineberry N, Kattah M, Su L, Utz P, Fathman C, et al. Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression. J Immunol. 2009;182:5919-28 pubmed 出版商
Jin W, Zhou X, Yu J, Cheng X, Sun S. Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK. Blood. 2009;113:6603-10 pubmed 出版商
van Gisbergen K, van Olffen R, van Beek J, Van Der Sluijs K, Arens R, Nolte M, et al. Protective CD8 T cell memory is impaired during chronic CD70-driven costimulation. J Immunol. 2009;182:5352-62 pubmed 出版商
Moon J, Chu H, Hataye J, Pagán A, Pepper M, McLachlan J, et al. Tracking epitope-specific T cells. Nat Protoc. 2009;4:565-81 pubmed 出版商
Steelman A, Dean D, Young C, Smith R, Prentice T, Meagher M, et al. Restraint stress modulates virus specific adaptive immunity during acute Theiler's virus infection. Brain Behav Immun. 2009;23:830-43 pubmed 出版商
Alves B, Leong J, Tamang D, Elliott V, Lowe M, Hudig D. Hydrolysis of tumor cell lipids after CTL-mediated death. Int Immunol. 2009;21:543-53 pubmed 出版商
Taylor J, Krawczyk C, Mohrs M, Pearce E. Th2 cell hyporesponsiveness during chronic murine schistosomiasis is cell intrinsic and linked to GRAIL expression. J Clin Invest. 2009;119:1019-28 pubmed 出版商
Phipps S, Lam C, Kaiko G, Foo S, Collison A, Mattes J, et al. Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses. Am J Respir Crit Care Med. 2009;179:883-93 pubmed 出版商
Sumi T, Fukushima A, Nishino K, Fukuda K, Kumagai N, Nishida T, et al. Treatment with FTY720 during the induction or effector phase suppresses the development of experimental allergic conjunctivitis in mice. Cell Biol Int. 2009;33:534-41 pubmed 出版商
Maillard I, Chen Y, Friedman A, Yang Y, Tubbs A, Shestova O, et al. Menin regulates the function of hematopoietic stem cells and lymphoid progenitors. Blood. 2009;113:1661-9 pubmed 出版商
French J, Roark C, Born W, O Brien R. Gammadelta T lymphocyte homeostasis is negatively regulated by beta2-microglobulin. J Immunol. 2009;182:1892-900 pubmed 出版商
Fortin G, Yurchenko K, Collette C, Rubio M, Villani A, Bitton A, et al. L-carnitine, a diet component and organic cation transporter OCTN ligand, displays immunosuppressive properties and abrogates intestinal inflammation. Clin Exp Immunol. 2009;156:161-71 pubmed 出版商
Moniz R, Chan A, Kelly K. Identification of dendritic cell subsets responding to genital infection by Chlamydia muridarum. FEMS Immunol Med Microbiol. 2009;55:226-36 pubmed 出版商
Shimazaki K, Chan A, Moniz R, Wadehra M, Nagy A, Coulam C, et al. Blockade of epithelial membrane protein 2 (EMP2) abrogates infection of Chlamydia muridarum murine genital infection model. FEMS Immunol Med Microbiol. 2009;55:240-9 pubmed 出版商
Qu P, Du H, Li Y, Yan C. Myeloid-specific expression of Api6/AIM/Sp alpha induces systemic inflammation and adenocarcinoma in the lung. J Immunol. 2009;182:1648-59 pubmed
Anghelina D, Zhao J, Trandem K, Perlman S. Role of regulatory T cells in coronavirus-induced acute encephalitis. Virology. 2009;385:358-67 pubmed 出版商
Liu X, Shen S, Manser T. Influence of B cell antigen receptor expression level on pathways of B cell tolerance induction. J Immunol. 2009;182:398-407 pubmed
Kawamura T, Takeda K, Kaneda H, Matsumoto H, Hayakawa Y, Raulet D, et al. NKG2A inhibits invariant NKT cell activation in hepatic injury. J Immunol. 2009;182:250-8 pubmed
Bauler T, Hendriks W, King P. The FERM and PDZ domain-containing protein tyrosine phosphatases, PTPN4 and PTPN3, are both dispensable for T cell receptor signal transduction. PLoS ONE. 2008;3:e4014 pubmed 出版商
Bauquet A, Jin H, Paterson A, Mitsdoerffer M, Ho I, Sharpe A, et al. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol. 2009;10:167-75 pubmed 出版商
Glanville S, Bekiaris V, Jenkinson E, Lane P, Anderson G, Withers D. Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization. Eur J Immunol. 2009;39:280-9 pubmed 出版商
Choi Y, Baumgarth N. Dual role for B-1a cells in immunity to influenza virus infection. J Exp Med. 2008;205:3053-64 pubmed 出版商
Zhang J, Wang J, Liu Y, Sidik H, Young K, Lodish H, et al. Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation. Blood. 2009;113:1304-14 pubmed 出版商
Malik N, Gilroy D, Kabouridis P. Regulation of growth and survival of activated T cells by cell-transducing inhibitors of Ras. FEBS Lett. 2009;583:61-9 pubmed 出版商
Wintermeyer P, Cheng C, Gehring S, Hoffman B, Holub M, Brossay L, et al. Invariant natural killer T cells suppress the neutrophil inflammatory response in a mouse model of cholestatic liver damage. Gastroenterology. 2009;136:1048-59 pubmed 出版商
van der Most R, Currie A, Mahendran S, Prosser A, Darabi A, Robinson B, et al. Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy. Cancer Immunol Immunother. 2009;58:1219-28 pubmed 出版商
Iijima N, Linehan M, Zamora M, Butkus D, Dunn R, Kehry M, et al. Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus. J Exp Med. 2008;205:3041-52 pubmed 出版商
Rieger M, Smejkal B, Schroeder T. Improved prospective identification of megakaryocyte-erythrocyte progenitor cells. Br J Haematol. 2009;144:448-51 pubmed 出版商
Kalaitzidis D, Neel B. Flow-cytometric phosphoprotein analysis reveals agonist and temporal differences in responses of murine hematopoietic stem/progenitor cells. PLoS ONE. 2008;3:e3776 pubmed 出版商
Kraus Z, Haring J, Bishop G. TNF receptor-associated factor 5 is required for optimal T cell expansion and survival in response to infection. J Immunol. 2008;181:7800-9 pubmed
Odegard J, Marks B, DiPlacido L, Poholek A, Kono D, Dong C, et al. ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity. J Exp Med. 2008;205:2873-86 pubmed 出版商
Drake P, Nathan J, Stock C, Chang P, Muench M, Nakata D, et al. Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses. J Immunol. 2008;181:6850-8 pubmed
Makino N, Toyofuku T, Takegahara N, Takamatsu H, Okuno T, Nakagawa Y, et al. Involvement of Sema4A in the progression of experimental autoimmune myocarditis. FEBS Lett. 2008;582:3935-40 pubmed 出版商
Ma L, Walter B, DeGuzman A, Muller H, Walker A. Trans-epithelial immune cell transfer during suckling modulates delayed-type hypersensitivity in recipients as a function of gender. PLoS ONE. 2008;3:e3562 pubmed 出版商
Wohler J, Barnum S. Nylon wool purification alters the activation of T cells. Mol Immunol. 2009;46:1007-10 pubmed 出版商
Baker R, Wagner D, Haskins K. CD40 on NOD CD4 T cells contributes to their activation and pathogenicity. J Autoimmun. 2008;31:385-92 pubmed 出版商
Katakai T, Suto H, Sugai M, Gonda H, Togawa A, Suematsu S, et al. Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs. J Immunol. 2008;181:6189-200 pubmed
Yadi H, Burke S, Madeja Z, Hemberger M, Moffett A, Colucci F. Unique receptor repertoire in mouse uterine NK cells. J Immunol. 2008;181:6140-7 pubmed
Dupré S, Redelman D, Hunter K. Microenvironment of the murine mammary carcinoma 4T1: endogenous IFN-gamma affects tumor phenotype, growth, and metastasis. Exp Mol Pathol. 2008;85:174-88 pubmed 出版商
Hadeiba H, Sato T, Habtezion A, Oderup C, Pan J, Butcher E. CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease. Nat Immunol. 2008;9:1253-60 pubmed 出版商
Wesselkamper S, Eppert B, Motz G, Lau G, Hassett D, Borchers M. NKG2D is critical for NK cell activation in host defense against Pseudomonas aeruginosa respiratory infection. J Immunol. 2008;181:5481-9 pubmed
Sadri N, Schneider R. Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease. J Invest Dermatol. 2009;129:657-70 pubmed 出版商
Shigeta A, Matsumoto M, Tedder T, Lowe J, Miyasaka M, Hirata T. An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation. Blood. 2008;112:4915-23 pubmed 出版商
Hase K, Takahashi D, Ebisawa M, Kawano S, Itoh K, Ohno H. Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease. PLoS ONE. 2008;3:e3033 pubmed 出版商
You Q, Cheng L, Kedl R, Ju C. Mechanism of T cell tolerance induction by murine hepatic Kupffer cells. Hepatology. 2008;48:978-90 pubmed 出版商
Wang Z, Liao Y, Yuan J, Zhang J, Dong J, Wang J. Analysis of specific Th1/Th2 helper cell responses and IgG subtype antibodies in anti-CD4 monoclonal antibody treated mice with autoimmune cardiomyopathy. J Huazhong Univ Sci Technolog Med Sci. 2008;28:409-14 pubmed 出版商
Kang T, Oh G, Scandella E, Bolinger B, Ludewig B, Kovalenko A, et al. Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. J Immunol. 2008;181:2522-32 pubmed
Lapinski P, Oliver J, Kamen L, Hughes E, Saunders T, King P. Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells. J Immunol. 2008;181:2019-27 pubmed
Nishimura R, Baker J, Beilhack A, Zeiser R, Olson J, Sega E, et al. In vivo trafficking and survival of cytokine-induced killer cells resulting in minimal GVHD with retention of antitumor activity. Blood. 2008;112:2563-74 pubmed 出版商
George J, Gooden C, Guo L, Guo W, Kirklin J. Role for CD4(+)CD25(+) T cells in inhibition of graft rejection by extracorporeal photopheresis. J Heart Lung Transplant. 2008;27:616-22 pubmed 出版商
Zhang J, Dong H, Wang B, Zhu S, Croy B. Dynamic changes occur in patterns of endometrial EFNB2/EPHB4 expression during the period of spiral arterial modification in mice. Biol Reprod. 2008;79:450-8 pubmed 出版商
Gautier E, Huby T, Saint Charles F, Ouzilleau B, Chapman M, Lesnik P. Enhanced dendritic cell survival attenuates lipopolysaccharide-induced immunosuppression and increases resistance to lethal endotoxic shock. J Immunol. 2008;180:6941-6 pubmed
Niikura M, Kamiya S, Kita K, Kobayashi F. Coinfection with nonlethal murine malaria parasites suppresses pathogenesis caused by Plasmodium berghei NK65. J Immunol. 2008;180:6877-84 pubmed
Chen X, Subleski J, Kopf H, Howard O, Männel D, Oppenheim J. Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells. J Immunol. 2008;180:6467-71 pubmed
Caserta S, Alessi P, Guarnerio J, Basso V, Mondino A. Synthetic CD4+ T cell-targeted antigen-presenting cells elicit protective antitumor responses. Cancer Res. 2008;68:3010-8 pubmed 出版商
Simelyte E, Criado G, Essex D, Uger R, Feldmann M, Williams R. CD200-Fc, a novel antiarthritic biologic agent that targets proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis. Arthritis Rheum. 2008;58:1038-43 pubmed 出版商
Cheng N, van de Wetering C, Knudson C. p27 deficiency cooperates with Bcl-2 but not Bax to promote T-cell lymphoma. PLoS ONE. 2008;3:e1911 pubmed 出版商
Huai J, Firat E, Nil A, Million D, Gaedicke S, Kanzler B, et al. Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice. Proc Natl Acad Sci U S A. 2008;105:5177-82 pubmed 出版商
Xiao C, Srinivasan L, Calado D, Patterson H, Zhang B, Wang J, et al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol. 2008;9:405-14 pubmed 出版商
Smithey M, Brandt S, Freitag N, Higgins D, Bouwer H. Stimulation of enhanced CD8 T cell responses following immunization with a hyper-antigen secreting intracytosolic bacterial pathogen. J Immunol. 2008;180:3406-16 pubmed
Xiu Y, Wong C, Bouaziz J, Hamaguchi Y, Wang Y, Pop S, et al. B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions. J Immunol. 2008;180:2863-75 pubmed
Zeytin H, Reali E, Zaharoff D, Rogers C, Schlom J, Greiner J. Targeted delivery of murine IFN-gamma using a recombinant fowlpox virus: NK cell recruitment to regional lymph nodes and priming of tumor-specific host immunity. J Interferon Cytokine Res. 2008;28:73-87 pubmed 出版商
Beaumier C, Mathew A, Bashyam H, Rothman A. Cross-reactive memory CD8(+) T cells alter the immune response to heterologous secondary dengue virus infections in mice in a sequence-specific manner. J Infect Dis. 2008;197:608-17 pubmed 出版商
Streetz K, Doyonnas R, Grimm D, Jenkins D, Fuess S, Perryman S, et al. Hepatic parenchymal replacement in mice by transplanted allogeneic hepatocytes is facilitated by bone marrow transplantation and mediated by CD4 cells. Hepatology. 2008;47:706-18 pubmed 出版商
Cullere X, Lauterbach M, Tsuboi N, Mayadas T. Neutrophil-selective CD18 silencing using RNA interference in vivo. Blood. 2008;111:3591-8 pubmed 出版商
Currie A, van der Most R, Broomfield S, Prosser A, Tovey M, Robinson B. Targeting the effector site with IFN-alphabeta-inducing TLR ligands reactivates tumor-resident CD8 T cell responses to eradicate established solid tumors. J Immunol. 2008;180:1535-44 pubmed
Watarai H, Nakagawa R, Omori Miyake M, Dashtsoodol N, Taniguchi M. Methods for detection, isolation and culture of mouse and human invariant NKT cells. Nat Protoc. 2008;3:70-8 pubmed 出版商
LeBleu V, Sugimoto H, Miller C, Gattone V, Kalluri R. Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease. Lab Invest. 2008;88:284-92 pubmed 出版商
Miu J, Mitchell A, Müller M, Carter S, Manders P, McQuillan J, et al. Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency. J Immunol. 2008;180:1217-30 pubmed
Castilow E, Olson M, Meyerholz D, Varga S. Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virus. J Virol. 2008;82:2196-207 pubmed
Paclik D, Berndt U, Guzy C, Dankof A, Danese S, Holzloehner P, et al. Galectin-2 induces apoptosis of lamina propria T lymphocytes and ameliorates acute and chronic experimental colitis in mice. J Mol Med (Berl). 2008;86:1395-406 pubmed
Steiner Q, Otten L, Hicks M, Kaya G, Grosjean F, Saeuberli E, et al. In vivo transformation of mouse conventional CD8alpha+ dendritic cells leads to progressive multisystem histiocytosis. Blood. 2008;111:2073-82 pubmed
Bahjat K, Prell R, Allen H, Liu W, Lemmens E, Leong M, et al. Activation of immature hepatic NK cells as immunotherapy for liver metastatic disease. J Immunol. 2007;179:7376-84 pubmed
Zhang T, Barber A, Sentman C. Chimeric NKG2D modified T cells inhibit systemic T-cell lymphoma growth in a manner involving multiple cytokines and cytotoxic pathways. Cancer Res. 2007;67:11029-36 pubmed
Albu D, Feng D, Bhattacharya D, Jenkins N, Copeland N, Liu P, et al. BCL11B is required for positive selection and survival of double-positive thymocytes. J Exp Med. 2007;204:3003-15 pubmed
Kopf H, de la Rosa G, Howard O, Chen X. Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells. Int Immunopharmacol. 2007;7:1819-24 pubmed
Stumhofer J, Silver J, Laurence A, Porrett P, Harris T, Turka L, et al. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol. 2007;8:1363-71 pubmed
Chiu B, Stolberg V, Zhang H, Chensue S. Increased Foxp3(+) Treg cell activity reduces dendritic cell co-stimulatory molecule expression in aged mice. Mech Ageing Dev. 2007;128:618-27 pubmed
Norris H, Martin A, Lybarger L, Andersen H, Chervenak D, Chervenak R. TCRbeta enhancer activation in early and late lymphoid progenitors. Cell Immunol. 2007;247:59-71 pubmed
Bradfute S, Braun D, Shamblin J, Geisbert J, Paragas J, Garrison A, et al. Lymphocyte death in a mouse model of Ebola virus infection. J Infect Dis. 2007;196 Suppl 2:S296-304 pubmed
Tenno M, Ohtsubo K, Hagen F, Ditto D, Zarbock A, Schaerli P, et al. Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity. Mol Cell Biol. 2007;27:8783-96 pubmed
Arechiga A, Bell B, Leverrier S, Weist B, Porter M, Wu Z, et al. A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2. J Immunol. 2007;179:5291-300 pubmed
Barber M, Zhang T, Gagne B, Van Ginderachter J, De Baetselier P, Sentman C. Ly49G2 receptor blockade reduces tumor burden in a leukemia model but not in a solid tumor model. Cancer Immunol Immunother. 2008;57:655-62 pubmed
Dupré S, Redelman D, Hunter K. The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci. Int J Exp Pathol. 2007;88:351-60 pubmed
Lee S, Grigorian A, Pawling J, Chen I, Gao G, Mozaffar T, et al. N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration. J Biol Chem. 2007;282:33725-34 pubmed
Heinz R, Waltenbaugh C. Ethanol consumption modifies dendritic cell antigen presentation in mice. Alcohol Clin Exp Res. 2007;31:1759-71 pubmed
Goto M, Takano Ishikawa Y, Ono H, Yoshida M, Yamaki K, Shinmoto H. Orally administered bisphenol A disturbed antigen specific immunoresponses in the naïve condition. Biosci Biotechnol Biochem. 2007;71:2136-43 pubmed
Bank U, Tadje J, Tager M, Wolke C, Bukowska A, Ittenson A, et al. Inhibition of alanyl-aminopeptidase on CD4+CD25+ regulatory T-cells enhances expression of FoxP3 and TGF-beta1 and ameliorates acute colitis in mice. Int J Mol Med. 2007;20:483-92 pubmed
Srinivasan M, Frauwirth K. Reciprocal NFAT1 and NFAT2 nuclear localization in CD8+ anergic T cells is regulated by suboptimal calcium signaling. J Immunol. 2007;179:3734-41 pubmed
Gaudreau S, Guindi C, Ménard M, Besin G, Dupuis G, Amrani A. Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells. J Immunol. 2007;179:3638-47 pubmed
Chappaz S, Flueck L, Farr A, Rolink A, Finke D. Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice. Blood. 2007;110:3862-70 pubmed
Heffner M, Fearon D. Loss of T cell receptor-induced Bmi-1 in the KLRG1(+) senescent CD8(+) T lymphocyte. Proc Natl Acad Sci U S A. 2007;104:13414-9 pubmed
Touma M, Antonini V, Kumar M, Osborn S, Bobenchik A, Keskin D, et al. Functional role for I kappa BNS in T cell cytokine regulation as revealed by targeted gene disruption. J Immunol. 2007;179:1681-92 pubmed
Chen W, Diao J, Stepkowski S, Zhang L. Both infiltrating regulatory T cells and insufficient antigen presentation are involved in long-term cardiac xenograft survival. J Immunol. 2007;179:1542-8 pubmed
Wu T, Wang Y, Lee Y, Wang J, Liu C, Wang S, et al. Immunity to avirulent enterovirus 71 and coxsackie A16 virus protects against enterovirus 71 infection in mice. J Virol. 2007;81:10310-5 pubmed
Ashour A, Lin X, Wang X, Turnquist H, Burns N, Tuli A, et al. CCL21 is an effective surgical neoadjuvant for treatment of mammary tumors. Cancer Biol Ther. 2007;6:1206-10 pubmed
Wang S, Diao H, Guan Q, Jevnikar A, Du C. Enhanced cardiac allograft survival by Vav1-Rac signaling blockade in a mouse model. Transpl Immunol. 2007;18:53-61 pubmed
Reiley W, Jin W, Lee A, Wright A, Wu X, Tewalt E, et al. Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses. J Exp Med. 2007;204:1475-85 pubmed
Taniguchi R, Guzior D, Kumar V. 2B4 inhibits NK-cell fratricide. Blood. 2007;110:2020-3 pubmed
Cauvi D, Cauvi G, Pollard K. Reduced expression of decay-accelerating factor 1 on CD4+ T cells in murine systemic autoimmune disease. Arthritis Rheum. 2007;56:1934-44 pubmed
Guarda G, Hons M, Soriano S, Huang A, Polley R, MartIn Fontecha A, et al. L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells. Nat Immunol. 2007;8:743-52 pubmed
Lee K, Scanga C, Bachelder E, Chen Q, Snapper C. TLR2 synergizes with both TLR4 and TLR9 for induction of the MyD88-dependent splenic cytokine and chemokine response to Streptococcus pneumoniae. Cell Immunol. 2007;245:103-10 pubmed
Meier D, Bornmann C, Chappaz S, Schmutz S, Otten L, Ceredig R, et al. Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells. Immunity. 2007;26:643-54 pubmed
Rossi S, Kim M, Leibbrandt A, Parnell S, Jenkinson W, Glanville S, et al. RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J Exp Med. 2007;204:1267-72 pubmed
Hashimoto K, Fujimoto T, Shimoda Y, Huang X, Sakamoto H, Ogawa M. Distinct hemogenic potential of endothelial cells and CD41+ cells in mouse embryos. Dev Growth Differ. 2007;49:287-300 pubmed
Grigorian A, Lee S, Tian W, Chen I, Gao G, Mendelsohn R, et al. Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis. J Biol Chem. 2007;282:20027-35 pubmed
Taylor R, Patel S, Lin E, Butler B, Lake J, Newberry R, et al. Lymphotoxin-independent expression of TNF-related activation-induced cytokine by stromal cells in cryptopatches, isolated lymphoid follicles, and Peyer's patches. J Immunol. 2007;178:5659-67 pubmed
Crozat K, Hoebe K, Ugolini S, Hong N, Janssen E, Rutschmann S, et al. Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis. J Exp Med. 2007;204:853-63 pubmed
Shibata K, Yamada H, Hara H, Kishihara K, Yoshikai Y. Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production. J Immunol. 2007;178:4466-72 pubmed
Back J, Chalifour A, Scarpellino L, Held W. Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact. Proc Natl Acad Sci U S A. 2007;104:3978-83 pubmed
Bauler T, Hughes E, Arimura Y, Mustelin T, Saunders T, King P. Normal TCR signal transduction in mice that lack catalytically active PTPN3 protein tyrosine phosphatase. J Immunol. 2007;178:3680-7 pubmed
McMillan B, McMillan S, Glover E, Bradfield C. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces premature activation of the KLF2 regulon during thymocyte development. J Biol Chem. 2007;282:12590-7 pubmed
Kang S, Piniecki R, HogenEsch H, Lim H, Wiebke E, Braun S, et al. Identification of a chemokine network that recruits FoxP3(+) regulatory T cells into chronically inflamed intestine. Gastroenterology. 2007;132:966-81 pubmed
Pop S, Wong C, He Q, Wang Y, Wallet M, Goudy K, et al. The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice. Diabetes. 2007;56:1395-402 pubmed
Min J, Huang L, Zimonjic D, Moskophidis D, Mivechi N. Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors. Oncogene. 2007;26:5086-97 pubmed
Brillard E, Pallandre J, Chalmers D, Ryffel B, Radlovic A, Seilles E, et al. Natural killer cells prevent CD28-mediated Foxp3 transcription in CD4+CD25- T lymphocytes. Exp Hematol. 2007;35:416-25 pubmed
Nobuhisa I, Ohtsu N, Okada S, Nakagata N, Taga T. Identification of a population of cells with hematopoietic stem cell properties in mouse aorta-gonad-mesonephros cultures. Exp Cell Res. 2007;313:965-74 pubmed
Erhardt A, Biburger M, Papadopoulos T, Tiegs G. IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice. Hepatology. 2007;45:475-85 pubmed
Humblet Baron S, Sather B, Anover S, Becker Herman S, Kasprowicz D, Khim S, et al. Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis. J Clin Invest. 2007;117:407-18 pubmed
Sharma R, Zheng L, Guo X, Fu S, Ju S, Jarjour W. Novel animal models for Sjögren's syndrome: expression and transfer of salivary gland dysfunction from regulatory T cell-deficient mice. J Autoimmun. 2006;27:289-296 pubmed 出版商
Zhang C, Lou J, Li N, Todorov I, Lin C, Cao Y, et al. Donor CD8+ T cells mediate graft-versus-leukemia activity without clinical signs of graft-versus-host disease in recipients conditioned with anti-CD3 monoclonal antibody. J Immunol. 2007;178:838-50 pubmed
Munroe M, Bishop G. A costimulatory function for T cell CD40. J Immunol. 2007;178:671-82 pubmed
Thomas M, Calamito M, Srivastava B, Maillard I, Pear W, Allman D. Notch activity synergizes with B-cell-receptor and CD40 signaling to enhance B-cell activation. Blood. 2007;109:3342-50 pubmed
Matsutani T, Ohmori T, Ogata M, Soga H, Kasahara S, Yoshioka T, et al. Comparison of CDR3 length among thymocyte subpopulations: impacts of MHC and BV segment on the CDR3 shortening. Mol Immunol. 2007;44:2378-87 pubmed
Ohno S, Ono N, Seki F, Takeda M, Kura S, Tsuzuki T, et al. Measles virus infection of SLAM (CD150) knockin mice reproduces tropism and immunosuppression in human infection. J Virol. 2007;81:1650-9 pubmed
Lohr J, Knoechel B, Wang J, Villarino A, Abbas A. Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. J Exp Med. 2006;203:2785-91 pubmed
Fife B, Guleria I, Gubbels Bupp M, Eagar T, Tang Q, Bour Jordan H, et al. Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway. J Exp Med. 2006;203:2737-47 pubmed
Furtado G, Piña B, Tacke F, Gaupp S, Van Rooijen N, Moran T, et al. A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells. J Immunol. 2006;177:6871-9 pubmed
Yurchenko E, Friedman H, Hay V, Peterson A, Piccirillo C. Ubiquitous expression of mRFP-1 in vivo by site-directed transgenesis. Transgenic Res. 2007;16:29-40 pubmed
Maillard I, Tu L, Sambandam A, Yashiro Ohtani Y, Millholland J, Keeshan K, et al. The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. J Exp Med. 2006;203:2239-45 pubmed
Fukushima A, Sumi T, Fukuda K, Yamaguchi T, Kumagai N, Nishida T, et al. Modulation of murine experimental allergic conjunctivitis by treatment with alpha-galactosylceramide. Immunol Lett. 2006;107:32-40 pubmed
Dupré S, Hunter K. Murine mammary carcinoma 4T1 induces a leukemoid reaction with splenomegaly: association with tumor-derived growth factors. Exp Mol Pathol. 2007;82:12-24 pubmed
Luke P, Deng J, Lian D, O Connell P, Garcia B, Jevnikar A, et al. Prolongation of allograft survival by administration of anti-CD45RB monoclonal antibody is due to alteration of CD45RBhi: CD45RBlo T-cell proportions. Am J Transplant. 2006;6:2023-34 pubmed
Anghelina D, Pewe L, Perlman S. Pathogenic role for virus-specific CD4 T cells in mice with coronavirus-induced acute encephalitis. Am J Pathol. 2006;169:209-22 pubmed
Grabig A, Paclik D, Guzy C, Dankof A, Baumgart D, Erckenbrecht J, et al. Escherichia coli strain Nissle 1917 ameliorates experimental colitis via toll-like receptor 2- and toll-like receptor 4-dependent pathways. Infect Immun. 2006;74:4075-82 pubmed
Matsutani T, Ohmori T, Ogata M, Soga H, Yoshioka T, Suzuki R, et al. Alteration of T-cell receptor repertoires during thymic T-cell development. Scand J Immunol. 2006;64:53-60 pubmed
Rubinstein M, Kovar M, Purton J, Cho J, Boyman O, Surh C, et al. Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}. Proc Natl Acad Sci U S A. 2006;103:9166-71 pubmed
Bagaeva L, Rao P, Powers J, Segal B. CXC chemokine ligand 13 plays a role in experimental autoimmune encephalomyelitis. J Immunol. 2006;176:7676-85 pubmed
Li Y, Brazzell J, Herrera A, Walcheck B. ADAM17 deficiency by mature neutrophils has differential effects on L-selectin shedding. Blood. 2006;108:2275-9 pubmed
Mukherjee S, Ahmed A, Malu S, Nandi D. Modulation of cell cycle progression by CTLA4-CD80/CD86 interactions on CD4+ T cells depends on strength of the CD3 signal: critical role for IL-2. J Leukoc Biol. 2006;80:66-74 pubmed
Vingert B, Adotevi O, Patin D, Jung S, Shrikant P, Freyburger L, et al. The Shiga toxin B-subunit targets antigen in vivo to dendritic cells and elicits anti-tumor immunity. Eur J Immunol. 2006;36:1124-35 pubmed
Gazit R, Gruda R, Elboim M, Arnon T, Katz G, Achdout H, et al. Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nat Immunol. 2006;7:517-23 pubmed
Richards J, Chang X, Blaser B, Caligiuri M, Zheng P, Liu Y. Tumor growth impedes natural-killer-cell maturation in the bone marrow. Blood. 2006;108:246-52 pubmed
Abadia Molina A, Ji H, Faubion W, Julien A, Latchman Y, Yagita H, et al. CD48 controls T-cell and antigen-presenting cell functions in experimental colitis. Gastroenterology. 2006;130:424-34 pubmed
McNerney M, Lee K, Zhou P, Molinero L, Mashayekhi M, Guzior D, et al. Role of natural killer cell subsets in cardiac allograft rejection. Am J Transplant. 2006;6:505-13 pubmed
Yao Z, Li P, Zhang Q, Schwarz E, Keng P, Arbini A, et al. Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. J Biol Chem. 2006;281:11846-55 pubmed
Fukushima A, Yamaguchi T, Ishida W, Fukata K, Yagita H, Ueno H. Roles of OX40 in the development of murine experimental allergic conjunctivitis: exacerbation and attenuation by stimulation and blocking of OX40. Invest Ophthalmol Vis Sci. 2006;47:657-63 pubmed
Geng H, Zhang G, Li D, Zhang H, Yuan Y, Zhu H, et al. Soluble form of T cell Ig mucin 3 is an inhibitory molecule in T cell-mediated immune response. J Immunol. 2006;176:1411-20 pubmed
Wohlfert E, Gorelik L, Mittler R, Flavell R, Clark R. Cutting edge: deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo. J Immunol. 2006;176:1316-20 pubmed
Hadzic T, Li L, Cheng N, Walsh S, Spitz D, Knudson C. The role of low molecular weight thiols in T lymphocyte proliferation and IL-2 secretion. J Immunol. 2005;175:7965-72 pubmed
Fukushima A, Yamaguchi T, Ishida W, Fukata K, Ueno H. TLR2 agonist ameliorates murine experimental allergic conjunctivitis by inducing CD4 positive T-cell apoptosis rather than by affecting the Th1/Th2 balance. Biochem Biophys Res Commun. 2006;339:1048-55 pubmed
Lin Y, Chen Y, Zeng Y, Wang T, Zeng S. Lymphocyte phenotyping and NK cell activity analysis in pregnant NOD/SCID mice. J Reprod Immunol. 2005;68:39-51 pubmed
Honda K, Nakamura K, Matsui N, Takahashi M, Kitamura Y, Mizutani T, et al. T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis. Inflamm Bowel Dis. 2005;11:1044-52 pubmed
Dighe A, Rodriguez M, Sabastian P, Xie X, McVoy M, Brown M. Requisite H2k role in NK cell-mediated resistance in acute murine cytomegalovirus-infected MA/My mice. J Immunol. 2005;175:6820-8 pubmed
Fukushima A, Yamaguchi T, Ishida W, Fukata K, Mittler R, Yagita H, et al. Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice. J Immunol. 2005;175:4897-903 pubmed
Yamagami S, Hamrah P, Zhang Q, Liu Y, Huq S, Dana M. Early ocular chemokine gene expression and leukocyte infiltration after high-risk corneal transplantation. Mol Vis. 2005;11:632-40 pubmed
Grimbaldeston M, Chen C, Piliponsky A, Tsai M, Tam S, Galli S. Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo. Am J Pathol. 2005;167:835-48 pubmed
Faunce D, Palmer J, Paskowicz K, Witte P, Kovacs E. CD1d-restricted NKT cells contribute to the age-associated decline of T cell immunity. J Immunol. 2005;175:3102-9 pubmed
Happel K, Lockhart E, Mason C, Porretta E, Keoshkerian E, Odden A, et al. Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs. Infect Immun. 2005;73:5782-8 pubmed
Prlic M, Gibbs J, Jameson S. Characteristics of NK cell migration early after vaccinia infection. J Immunol. 2005;175:2152-7 pubmed
Zhang N, He Y. An essential role for c-FLIP in the efficient development of mature T lymphocytes. J Exp Med. 2005;202:395-404 pubmed
Myers M, Dragone L, Weiss A. Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation. J Cell Biol. 2005;170:285-94 pubmed
Chen C, Grimbaldeston M, Tsai M, Weissman I, Galli S. Identification of mast cell progenitors in adult mice. Proc Natl Acad Sci U S A. 2005;102:11408-13 pubmed
Fujimura S, Xing Y, Takeya M, Yamashita Y, Ohshima K, Kuwahara K, et al. Increased expression of germinal center-associated nuclear protein RNA-primase is associated with lymphomagenesis. Cancer Res. 2005;65:5925-34 pubmed
Zhang T, Lemoi B, Sentman C. Chimeric NK-receptor-bearing T cells mediate antitumor immunotherapy. Blood. 2005;106:1544-51 pubmed
Pop S, Wong C, Culton D, Clarke S, Tisch R. Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes. J Exp Med. 2005;201:1333-46 pubmed
Manders P, Hunter P, Telaranta A, Carr J, Marshall J, Carrasco M, et al. BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes. Proc Natl Acad Sci U S A. 2005;102:7418-25 pubmed
Bronte V, Kasic T, Gri G, Gallana K, Borsellino G, Marigo I, et al. Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers. J Exp Med. 2005;201:1257-68 pubmed
Mukherjee S, Ahmed A, Nandi D. CTLA4-CD80/CD86 interactions on primary mouse CD4+ T cells integrate signal-strength information to modulate activation with Concanavalin A. J Leukoc Biol. 2005;78:144-57 pubmed
Setoguchi R, Hori S, Takahashi T, Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med. 2005;201:723-35 pubmed
Sturm A, Rilling K, Baumgart D, Gargas K, Abou Ghazalé T, Raupach B, et al. Escherichia coli Nissle 1917 distinctively modulates T-cell cycling and expansion via toll-like receptor 2 signaling. Infect Immun. 2005;73:1452-65 pubmed
Kataoka H, Takahashi S, Takase K, Yamasaki S, Yokosuka T, Koike T, et al. CD25(+)CD4(+) regulatory T cells exert in vitro suppressive activity independent of CTLA-4. Int Immunol. 2005;17:421-7 pubmed
Lee K, McNerney M, Stepp S, Mathew P, Schatzle J, Bennett M, et al. 2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells. J Exp Med. 2004;199:1245-54 pubmed
Hsu L, Liang H, Johnson K, Kang C, Schlissel M. Pax5 activates immunoglobulin heavy chain V to DJ rearrangement in transgenic thymocytes. J Exp Med. 2004;199:825-30 pubmed
Pfeifhofer C, Kofler K, Gruber T, Tabrizi N, Lutz C, Maly K, et al. Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells. J Exp Med. 2003;197:1525-35 pubmed
Okazaki I, Hiai H, Kakazu N, Yamada S, Muramatsu M, Kinoshita K, et al. Constitutive expression of AID leads to tumorigenesis. J Exp Med. 2003;197:1173-81 pubmed
Kieper W, Tan J, Bondi Boyd B, Gapin L, Sprent J, Ceredig R, et al. Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells. J Exp Med. 2002;195:1533-9 pubmed
Iqbal N, Oliver J, Wagner F, Lazenby A, Elson C, Weaver C. T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis. J Exp Med. 2002;195:71-84 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD3e Monoclonal Antibody (145-2C11), eBioscience™
目录# :
14-0031-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
亚美尼亚仓鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
物种 :
小鼠
克隆 :
145-2C11
抗体亚型 :
IgG
储存 :
4° C
描述 :
The CD3 subunit complex which is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. The genes encoding the CD3 epsilon, gamma and delta polypeptides are located on chromosome 11. Defects in the CD3 gene are associated with CD3 immunodeficiency.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
别名 :
4930549J05Rik; A430104F18Rik; AI504783; antigen CD3D, delta polypeptide (TiT3 complex); antigen CD3E, epsilon polypeptide (TiT3 complex); antigen CD3G, gamma polypeptide; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; CD3; CD3 antigen delta chain; CD3 antigen delta polypeptide; CD3 antigen gamma chain; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 antigen, epsilon polypeptide; CD3 antigen, gamma polypeptide; CD3 antigen, zeta polypeptide; CD3 delta; CD3 epsilon; CD3 epsilon chain; CD3 epsilon subunit; CD3 epsilon subunit precursor; CD3 gamma-chain; CD3 glycoprotein; CD3 glycoprotein precursor; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3 molecule, epsilon; CD3 molecule, epsilon polypeptide; CD3 molecule, gamma; CD3 molecule, gamma polypeptide; CD3 protein; CD3 type I transmembrane glycoprotein; CD3 type I transmembrane glycoprotein precursor; CD3 zeta chain; Cd3d; CD3D antigen delta; CD3D antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; Cd3e; CD3E antigen, epsilon polypeptide; CD3E antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3epsilon; CD3-epsilon; Cd3-eta; Cd3g; CD3G antigen, gamma polypeptide; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; Cd3h; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; Ctg3; Ctg-3; FLJ18683; IMD17; IMD18; IMD19; IMD25; Leu-4; OKT3, delta chain; T3/TCR complex; T3d; T3e; T3g; T3Z; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 epsilon chain; T-cell receptor CD3 epsilon subunit; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 delta chain; T-cell receptor T3 eta chain; T-cell receptor T3 gamma chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain; T-cell surface glycoprotein CD3 zeta chain; T-cell surface protein; TcR CD3 delta-chain; TcR CD3 gamma-chain; TCR zeta chain; TCR zeta chain subunit; TCRE; Tcrk; TCRZ; TCRzeta; TiT3 complex; type I transmembrane protein; T-cell surface molecule CD3
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国