产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD19 Monoclonal Antibody (6OMP31), eBioscience™
目录 :
14-0194-82
规格 :
100微克
价格 :
325美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
6OMP31
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 4
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 0.5 ug/ml; 图 4a
Rodríguez Lorenzo S, Konings J, van der Pol S, Kamermans A, Amor S, van Horssen J, et al. Inflammation of the choroid plexus in progressive multiple sclerosis: accumulation of granulocytes and T cells. Acta Neuropathol Commun. 2020;8:9 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6d
Rühl J, Citterio C, Engelmann C, Haigh T, Dzionek A, Dreyer J, et al. Heterologous prime-boost vaccination protects against EBV antigen-expressing lymphomas. J Clin Invest. 2019;129:2071-2087 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 2
Krishnan B, Massilamany C, Basavalingappa R, Gangaplara A, Rajasekaran R, Afzal M, et al. Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice. J Immunol. 2018;200:523-537 pubmed 出版商
Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, et al. Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice. World J Gastroenterol. 2020;26:918-932 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD19 Monoclonal Antibody (6OMP31), eBioscience™
目录# :
14-0194-82
规格 :
100微克
价格 :
325美元
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Frozen): 0.5 µg/mL, Immunohistochemistry (Paraffin): 0.5 µg/mL, Western Blot: 1 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
6OMP31
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Frozen): 0.5 µg/mL, Immunohistochemistry (Paraffin): 0.5 µg/mL, Western Blot: 1 µg/mL
别名 :
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国