产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD28 Monoclonal Antibody (37.51), eBioscience™
目录 :
14-0281-86
规格 :
1毫克
价格 :
美国437
克隆性 :
单克隆
宿主 :
Syrian golden hamster
共轭标签 :
未共轭
克隆名称 :
37.51
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫沉淀, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 186
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 1d
Xing S, Gai K, Li X, Shao P, Zeng Z, Zhao X, et al. Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells. J Exp Med. 2019;: pubmed 出版商
  • 流式细胞仪; 人类; 图 6a
Muscate F, Stetter N, Schramm C, Schulze zur Wiesch J, Bosurgi L, Jacobs T. HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage. Front Immunol. 2018;9:2611 pubmed 出版商
  • 抑制或激活实验; 小鼠; 3 ug/ml; 图 2
Swamy M, Pathak S, Grzes K, Damerow S, Sinclair L, van Aalten D, et al. Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy. Nat Immunol. 2016;17:712-20 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4
Kabat A, Harrison O, Riffelmacher T, Moghaddam A, Pearson C, Laing A, et al. The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. elife. 2016;5:e12444 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4
Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s9
Ying W, Tseng A, Chang R, Wang H, Lin Y, Kanameni S, et al. miR-150 regulates obesity-associated insulin resistance by controlling B cell functions. Sci Rep. 2016;6:20176 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Verma S, Weiskopf D, Gupta A, McDonald B, Peters B, Sette A, et al. Cytomegalovirus-Specific CD4 T Cells Are Cytolytic and Mediate Vaccine Protection. J Virol. 2016;90:650-8 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 1f
  • 流式细胞仪; 小鼠; 1 ug/ml; 图 1b
Nakatsukasa H, Zhang D, Maruyama T, Chen H, Cui K, Ishikawa M, et al. The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. Nat Immunol. 2015;16:1077-84 pubmed 出版商
  • 抑制或激活实验; 小鼠; 1:500
Pearce V, Bouabe H, MacQueen A, Carbonaro V, Okkenhaug K. PI3Kδ Regulates the Magnitude of CD8+ T Cell Responses after Challenge with Listeria monocytogenes. J Immunol. 2015;195:3206-17 pubmed 出版商
  • 抑制或激活实验; 小鼠
Sharma S, Chintala N, Vadrevu S, Patel J, Karbowniczek M, Markiewski M. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J Immunol. 2015;194:5529-38 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Buchwald Z, Yang C, Nellore S, Shashkova E, Davis J, Cline A, et al. A Bone Anabolic Effect of RANKL in a Murine Model of Osteoporosis Mediated Through FoxP3+ CD8 T Cells. J Bone Miner Res. 2015;30:1508-22 pubmed 出版商
  • 抑制或激活实验; 小鼠; 2 ug/ml
Sakaguchi S, Hombauer M, Hassan H, Tanaka H, Yasmin N, Naoe Y, et al. A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells. J Leukoc Biol. 2015;97:635-44 pubmed 出版商
  • 抑制或激活实验; 小鼠; 5 ug/ml
  • 流式细胞仪; 小鼠; 5 ug/ml
Arndt B, Witkowski L, Ellwart J, Seissler J. CD8+ CD122+ PD-1- effector cells promote the development of diabetes in NOD mice. J Leukoc Biol. 2015;97:111-20 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 1e
Backer R, Helbig C, Gentek R, Kent A, Laidlaw B, Dominguez C, et al. A central role for Notch in effector CD8(+) T cell differentiation. Nat Immunol. 2014;15:1143-51 pubmed 出版商
  • 抑制或激活实验; 小鼠
Bashour K, Gondarenko A, Chen H, Shen K, Liu X, Huse M, et al. CD28 and CD3 have complementary roles in T-cell traction forces. Proc Natl Acad Sci U S A. 2014;111:2241-6 pubmed 出版商
  • 抑制或激活实验; 小鼠
Yang C, Li J, Chiu L, Lan J, Chen D, Chuang H, et al. Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation. J Immunol. 2014;192:1547-57 pubmed 出版商
  • 流式细胞仪; 小鼠; 2 ug/ml
Hu Y, Xiao H, Shi T, Oppenheim J, Chen X. Progranulin promotes tumour necrosis factor-induced proliferation of suppressive mouse CD4? Foxp3? regulatory T cells. Immunology. 2014;142:193-201 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Salinas N, Olguín J, Castellanos C, Saavedra R. T cell suppression in vitro during Toxoplasma gondii infection is the result of IL-2 competition between Tregs and T cells leading to death of proliferating T cells. Scand J Immunol. 2014;79:1-11 pubmed 出版商
  • 抑制或激活实验; 小鼠; 200 ng/ml
Sheng H, Wang Y, Jin Y, Zhang Q, Zhang Y, Wang L, et al. A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res. 2008;18:846-57 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Nakae S, Iwakura Y, Suto H, Galli S. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81:1258-68 pubmed
  • 流式细胞仪; 小鼠; 10 ug/ml; 图 2
Krieg C, Han P, Stone R, Goularte O, Kaye J. Functional analysis of B and T lymphocyte attenuator engagement on CD4+ and CD8+ T cells. J Immunol. 2005;175:6420-7 pubmed
Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed 出版商
Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed 出版商
Bending D, Paduraru A, Ducker C, Prieto Martin P, Crompton T, Ono M. A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme. EMBO J. 2018;37: pubmed 出版商
Sinclair L, Neyens D, Ramsay G, Taylor P, Cantrell D. Single cell analysis of kynurenine and System L amino acid transport in T cells. Nat Commun. 2018;9:1981 pubmed 出版商
Zhang J, Qiu X, Zhang N, Tang W, Gober H, Li D, et al. Bu‑Shen‑Ning‑Xin decoction suppresses osteoclastogenesis by modulating RANKL/OPG imbalance in the CD4+ T lymphocytes of ovariectomized mice. Int J Mol Med. 2018;42:299-308 pubmed 出版商
Tong H, Miyake Y, Mi ichi F, Iwakura Y, Hara H, Yoshida H. Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells. PLoS ONE. 2018;13:e0195119 pubmed 出版商
Moreno Fernandez M, Giles D, Stankiewicz T, Sheridan R, Karns R, Cappelletti M, et al. Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease. JCI Insight. 2018;3: pubmed 出版商
Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine T, et al. Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression. J Clin Invest. 2018;128:2487-2499 pubmed 出版商
Fransen M, Benonisson H, van Maren W, Sow H, Breukel C, Linssen M, et al. A Restricted Role for FcγR in the Regulation of Adaptive Immunity. J Immunol. 2018;200:2615-2626 pubmed 出版商
Mencarelli A, Vacca M, Khameneh H, Acerbi E, Tay A, Zolezzi F, et al. Calcineurin B in CD4+ T Cells Prevents Autoimmune Colitis by Negatively Regulating the JAK/STAT Pathway. Front Immunol. 2018;9:261 pubmed 出版商
Villadiego J, Labrador Garrido A, Franco J, Leal Lasarte M, De Genst E, Dobson C, et al. Immunization with ?-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model. Glia. 2018;66:191-205 pubmed 出版商
Morillon Y, Hammond S, Durham N, Schlom J, Greiner J. Enhanced immunotherapy by combining a vaccine with a novel murine GITR ligand fusion protein. Oncotarget. 2017;8:73469-73482 pubmed 出版商
Wang J, He N, Zhang N, Quan D, Zhang S, Zhang C, et al. NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection. Nat Commun. 2017;8:959 pubmed 出版商
Basler M, Maurits E, de Bruin G, Koerner J, Overkleeft H, Groettrup M. Amelioration of autoimmunity with an inhibitor selectively targeting all active centers of the immunoproteasome. Br J Pharmacol. 2017;: pubmed 出版商
Vonk M, Wagenaar L, Pieters R, Knippels L, Willemsen L, Smit J, et al. The efficacy of oral and subcutaneous antigen-specific immunotherapy in murine cow's milk- and peanut allergy models. Clin Transl Allergy. 2017;7:35 pubmed 出版商
Gulen M, Koch U, Haag S, Schüler F, Apetoh L, Villunger A, et al. Signalling strength determines proapoptotic functions of STING. Nat Commun. 2017;8:427 pubmed 出版商
Kurachi M, Kurachi J, Chen Z, Johnson J, Khan O, Bengsch B, et al. Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function. Nat Protoc. 2017;12:1980-1998 pubmed 出版商
Jang E, Lee H, Lee G, Oh A, Cha J, Igarashi K, et al. Bach2 represses the AP-1-driven induction of interleukin-2 gene transcription in CD4+ T cells. BMB Rep. 2017;50:472-477 pubmed
He Z, Ma J, Wang R, Zhang J, Huang Z, Wang F, et al. A two-amino-acid substitution in the transcription factor RORγt disrupts its function in TH17 differentiation but not in thymocyte development. Nat Immunol. 2017;18:1128-1138 pubmed 出版商
Hosokawa T, Kimura T, Nada S, Okuno T, Ito D, Kang S, et al. Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function. J Immunol. 2017;199:2008-2019 pubmed 出版商
Van Den Ham K, Smith L, Richer M, Olivier M. Protein Tyrosine Phosphatase Inhibition Prevents Experimental Cerebral Malaria by Precluding CXCR3 Expression on T Cells. Sci Rep. 2017;7:5478 pubmed 出版商
Chen J, Martindale J, Cramer C, Gorospe M, Atasoy U, Drew P, et al. The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells. J Biol Chem. 2017;292:14532-14543 pubmed 出版商
Mancera P, Wappenhans B, Cordobilla B, Virgili N, Pugliese M, Rueda F, et al. Natural Docosahexaenoic Acid in the Triglyceride Form Attenuates In Vitro Microglial Activation and Ameliorates Autoimmune Encephalomyelitis in Mice. Nutrients. 2017;9: pubmed 出版商
Dombrowski Y, O Hagan T, Dittmer M, Penalva R, Mayoral S, Bankhead P, et al. Regulatory T cells promote myelin regeneration in the central nervous system. Nat Neurosci. 2017;20:674-680 pubmed 出版商
Prados Rosales R, Carreño L, Cheng T, Blanc C, Weinrick B, Malek A, et al. Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine. PLoS Pathog. 2017;13:e1006250 pubmed 出版商
PENBERTHY K, BUCKLEY M, Arandjelovic S, Ravichandran K. Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells. PLoS ONE. 2017;12:e0173386 pubmed 出版商
Sun X, Liu S, Wang D, Zhang Y, Li W, Guo Y, et al. Colorectal cancer cells suppress CD4+ T cells immunity through canonical Wnt signaling. Oncotarget. 2017;8:15168-15181 pubmed 出版商
Britton G, Ambler R, Clark D, Hill E, Tunbridge H, McNally K, et al. PKC? links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton. elife. 2017;6: pubmed 出版商
Araujo L, Khim P, Mkhikian H, Mortales C, Demetriou M. Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation. elife. 2017;6: pubmed 出版商
Song M, Nair V, Oh K. Vitamin C enhances the expression of IL17 in a Jmjd2-dependent manner. BMB Rep. 2017;50:49-54 pubmed
Davis R, Silvin C, Allen C. Avoiding phagocytosis-related artifact in myeloid derived suppressor cell T-lymphocyte suppression assays. J Immunol Methods. 2017;440:12-18 pubmed 出版商
Stentzel S, Teufelberger A, Nordengrün M, Kolata J, Schmidt F, Van Crombruggen K, et al. Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus. J Allergy Clin Immunol. 2017;139:492-500.e8 pubmed 出版商
Kumar P, Kolls J. Lymphocyte Isolation, Th17 Cell Differentiation, Activation, and Staining. Bio Protoc. 2016;6: pubmed 出版商
Blanquiceth Y, Rodríguez Perea A, Tabares Guevara J, Correa L, Sánchez M, Ramirez Pineda J, et al. Increase of Frequency and Modulation of Phenotype of Regulatory T Cells by Atorvastatin Is Associated with Decreased Lung Inflammatory Cell Infiltration in a Murine Model of Acute Allergic Asthma. Front Immunol. 2016;7:620 pubmed 出版商
Gomes R, Cavalcanti K, Teixeira C, Carvalho A, Mattos P, Cristal J, et al. Immunity to Lutzomyia whitmani Saliva Protects against Experimental Leishmania braziliensis Infection. PLoS Negl Trop Dis. 2016;10:e0005078 pubmed 出版商
Massaad M, Zhou J, Tsuchimoto D, Chou J, Jabara H, Janssen E, et al. Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. J Clin Invest. 2016;126:4219-4236 pubmed 出版商
Akhter N, Takeda Y, Nara H, Araki A, Ishii N, Asao N, et al. Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 (Ape1/Ref-1) Modulates Antigen Presenting Cell-mediated T Helper Cell Type 1 Responses. J Biol Chem. 2016;291:23672-23680 pubmed
Eil R, Vodnala S, Clever D, Klebanoff C, Sukumar M, Pan J, et al. Ionic immune suppression within the tumour microenvironment limits T cell effector function. Nature. 2016;537:539-543 pubmed 出版商
Oudhoff M, Antignano F, Chenery A, Burrows K, Redpath S, Braam M, et al. Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection. PLoS Pathog. 2016;12:e1005876 pubmed 出版商
Zakostelska Z, Málková J, Klimesova K, Rossmann P, Hornova M, Novosádová I, et al. Intestinal Microbiota Promotes Psoriasis-Like Skin Inflammation by Enhancing Th17 Response. PLoS ONE. 2016;11:e0159539 pubmed 出版商
He Z, Wang F, Ma J, Sen S, Zhang J, Gwack Y, et al. Ubiquitination of ROR?t at Lysine 446 Limits Th17 Differentiation by Controlling Coactivator Recruitment. J Immunol. 2016;197:1148-58 pubmed 出版商
Xu Y, Zhao F, Qiu Q, Chen K, Wei J, Kong Q, et al. The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity. Nat Commun. 2016;7:12073 pubmed 出版商
Venetz D, Koovely D, Weder B, Neri D. Targeted Reconstitution of Cytokine Activity upon Antigen Binding using Split Cytokine Antibody Fusion Proteins. J Biol Chem. 2016;291:18139-47 pubmed 出版商
Hidalgo Cantabrana C, Algieri F, Rodríguez Nogales A, Vezza T, Martinez Camblor P, Margolles A, et al. Effect of a Ropy Exopolysaccharide-Producing Bifidobacterium animalis subsp. lactis Strain Orally Administered on DSS-Induced Colitis Mice Model. Front Microbiol. 2016;7:868 pubmed 出版商
Holmgaard R, Zamarin D, Lesokhin A, Merghoub T, Wolchok J. Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressing tumors. EBioMedicine. 2016;6:50-58 pubmed 出版商
Rapp M, Grassmann S, Chaloupka M, Layritz P, Krüger S, Ormanns S, et al. C-C chemokine receptor type-4 transduction of T cells enhances interaction with dendritic cells, tumor infiltration and therapeutic efficacy of adoptive T cell transfer. Oncoimmunology. 2016;5:e1105428 pubmed
Rowe R, Ellis G, Harrison J, Bachstetter A, Corder G, Van Eldik L, et al. Diffuse traumatic brain injury induces prolonged immune dysregulation and potentiates hyperalgesia following a peripheral immune challenge. Mol Pain. 2016;12: pubmed 出版商
Bravo B, Gallego M, Flores A, Bornstein R, Puente Bedia A, Hernandez J, et al. Restrained Th17 response and myeloid cell infiltration into the central nervous system by human decidua-derived mesenchymal stem cells during experimental autoimmune encephalomyelitis. Stem Cell Res Ther. 2016;7:43 pubmed 出版商
Lee J, Kannarkat G, Chung J, Joon Lee H, Graham K, Tansey M. RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2016;13:24 pubmed 出版商
Polansky J, Bahri R, Divivier M, Duitman E, Vock C, Goyeneche Patino D, et al. High dose CD11c-driven IL15 is sufficient to drive NK cell maturation and anti-tumor activity in a trans-presentation independent manner. Sci Rep. 2016;6:19699 pubmed 出版商
Wei J, Long L, Yang K, Guy C, Shrestha S, Chen Z, et al. Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis. Nat Immunol. 2016;17:277-85 pubmed 出版商
Milanez Almeida P, Ulas T, Pasztoi M, Glage S, Schughart K, Lutz M, et al. CD11b(+)Ly6C(++)Ly6G(-) Cells with Suppressive Activity Towards T Cells Accumulate in Lungs of Influenza a Virus-Infected Mice. Eur J Microbiol Immunol (Bp). 2015;5:246-55 pubmed 出版商
Mackay L, Wynne Jones E, Freestone D, Pellicci D, Mielke L, Newman D, et al. T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate. Immunity. 2015;43:1101-11 pubmed 出版商
Jabara H, Boyden S, Chou J, Ramesh N, Massaad M, Benson H, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016;48:74-8 pubmed 出版商
Intosalmi J, Ahlfors H, Rautio S, Mannerstöm H, Chen Z, Lahesmaa R, et al. Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data. BMC Syst Biol. 2015;9:81 pubmed 出版商
Zhong Y, Tang H, Wang X, Zeng Q, Liu Y, Zhao X, et al. Intranasal immunization with heat shock protein 60 induces CD4(+) CD25(+) GARP(+) and type 1 regulatory T cells and inhibits early atherosclerosis. Clin Exp Immunol. 2016;183:452-68 pubmed 出版商
Yuan C, Sun X, Zhu C, Liu S, Wu L, Chen H, et al. Amphiregulin activates regulatory T lymphocytes and suppresses CD8+ T cell-mediated anti-tumor response in hepatocellular carcinoma cells. Oncotarget. 2015;6:32138-53 pubmed 出版商
Lee J, Dustin M, KAM L. A microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays. Integr Biol (Camb). 2015;7:1442-53 pubmed 出版商
Farez M, Mascanfroni I, Méndez Huergo S, Yeste A, Murugaiyan G, Garo L, et al. Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses. Cell. 2015;162:1338-52 pubmed 出版商
Li W, Liu H. CCL20-CCR6 Cytokine Network Facilitate Treg Activity in Advanced Grades and Metastatic Variants of Hepatocellular Carcinoma. Scand J Immunol. 2016;83:33-7 pubmed 出版商
Yang B, Hagemann S, Mamareli P, Lauer U, Hoffmann U, Beckstette M, et al. Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation. Mucosal Immunol. 2016;9:444-57 pubmed 出版商
Takada K, Van Laethem F, Xing Y, Akane K, Suzuki H, Murata S, et al. TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8(+) T cells. Nat Immunol. 2015;16:1069-76 pubmed 出版商
Bittner S, Bobak N, Hofmann M, Schuhmann M, Ruck T, Göbel K, et al. Murine K2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation due to Compensatory K2P3.1- and KV1.3-Dependent Mechanisms. Int J Mol Sci. 2015;16:16880-96 pubmed 出版商
Schumann J, Stanko K, Schliesser U, Appelt C, Sawitzki B. Differences in CD44 Surface Expression Levels and Function Discriminates IL-17 and IFN-γ Producing Helper T Cells. PLoS ONE. 2015;10:e0132479 pubmed 出版商
Vaeth M, Zee I, Concepcion A, Maus M, Shaw P, Portal Celhay C, et al. Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells. J Immunol. 2015;195:1202-17 pubmed 出版商
Shimizu K, Sakurai F, Tomita K, Nagamoto Y, Nakamura S, Katayama K, et al. Suppression of leaky expression of adenovirus genes by insertion of microRNA-targeted sequences in the replication-incompetent adenovirus vector genome. Mol Ther Methods Clin Dev. 2014;1:14035 pubmed 出版商
Römer C, Engel O, Winek K, Hochmeister S, Zhang T, Royl G, et al. Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke. J Neurosci. 2015;35:7777-94 pubmed 出版商
Gillgrass A, Chew M, Krneta T, Ashkar A. Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model. BMC Cancer. 2015;15:293 pubmed 出版商
McPherson R, Turner D, Mair I, O Connor R, Anderton S. T-bet Expression by Foxp3(+) T Regulatory Cells is Not Essential for Their Suppressive Function in CNS Autoimmune Disease or Colitis. Front Immunol. 2015;6:69 pubmed 出版商
Hill E, Ng T, Burton B, Oakley C, Malik K, Wraith D. Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter. Eur J Immunol. 2015;45:1103-15 pubmed 出版商
Shindo Y, Unsinger J, Burnham C, Green J, Hotchkiss R. Interleukin-7 and anti-programmed cell death 1 antibody have differing effects to reverse sepsis-induced immunosuppression. Shock. 2015;43:334-43 pubmed 出版商
Li C, Lin M, Chu S, Tu P, Fang C, Yen C, et al. Role of glycine N-methyltransferase in the regulation of T-cell responses in experimental autoimmune encephalomyelitis. Mol Med. 2015;20:684-96 pubmed 出版商
Gewies A, Gorka O, Bergmann H, Pechloff K, Petermann F, Jeltsch K, et al. Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation. Cell Rep. 2014;9:1292-305 pubmed 出版商
Sharir R, Semo J, Shimoni S, Ben Mordechai T, Landa Rouben N, Maysel Auslender S, et al. Experimental myocardial infarction induces altered regulatory T cell hemostasis, and adoptive transfer attenuates subsequent remodeling. PLoS ONE. 2014;9:e113653 pubmed 出版商
Thueson L, Emmons T, Browning D, Kreitinger J, Shepherd D, Wetzel S. In vitro exposure to the herbicide atrazine inhibits T cell activation, proliferation, and cytokine production and significantly increases the frequency of Foxp3+ regulatory T cells. Toxicol Sci. 2015;143:418-29 pubmed 出版商
Kobayashi S, Hara A, Isagawa T, Manabe I, Takeda K, Maruyama T. The nuclear IκB family protein IκBNS influences the susceptibility to experimental autoimmune encephalomyelitis in a murine model. PLoS ONE. 2014;9:e110838 pubmed 出版商
Linterman M, Denton A, Divekar D, Zvetkova I, Kane L, Ferreira C, et al. CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection. elife. 2014;3: pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD28 Monoclonal Antibody (37.51), eBioscience™
目录# :
14-0281-86
规格 :
1毫克
价格 :
美国437
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
Syrian Hamster
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent
物种 :
小鼠
克隆 :
37.51
抗体亚型 :
IgG
储存 :
4° C
描述 :
CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR. The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells. Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezary's Disease.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent
别名 :
antigen CD28; BOS_1949; CD28; CD28 antigen; CD28 antigen (Tp44); Cd28 molecule; CD28 precursor protein; CD28RNA; cell surface protein; CHT28; costimulatory molecule B7 receptor CD28; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国