产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), eBioscience™
目录 :
14-0541-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
YN1/1.7。 4
反应物种 :
人类, 小鼠
应用 :
免疫组化, 中和反应, 流式细胞仪
更多信息或购买 :
文章摘录数: 40
出版应用/物种/样本/稀释 | 参考文献 |
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| Zhang F, Marcus W, Goyal N, Selvaraj P, Springer T, Zhu C. Two-dimensional kinetics regulation of alphaLbeta2-ICAM-1 interaction by conformational changes of the alphaL-inserted domain. J Biol Chem. 2005;280:42207-18 pubmed
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Birbach A, Eisenbarth D, Kozakowski N, Ladenhauf E, Schmidt Supprian M, Schmid J. Persistent inflammation leads to proliferative neoplasia and loss of smooth muscle cells in a prostate tumor model. Neoplasia. 2011;13:692-703 pubmed
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Togbe D, Schofield L, Grau G, Schnyder B, Boissay V, Charron S, et al. Murine cerebral malaria development is independent of toll-like receptor signaling. Am J Pathol. 2007;170:1640-8 pubmed
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Zhou J, Friend D, Feldweg A, Daheshia M, Li L, Austen K, et al. Prevention of lipopolysaccharide-induced microangiopathy by gp49B1: evidence for an important role for gp49B1 expression on neutrophils. J Exp Med. 2003;198:1243-51 pubmed
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Kumasaka T, Quinlan W, Doyle N, Condon T, Sligh J, Takei F, et al. Role of the intercellular adhesion molecule-1(ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides, anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice. J Clin Invest. 1996;97:2362-9 pubmed
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Burns A, Takei F, Doerschuk C. Quantitation of ICAM-1 expression in mouse lung during pneumonia. J Immunol. 1994;153:3189-98 pubmed
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Jevnikar A, Wuthrich R, Takei F, Xu H, Brennan D, Glimcher L, et al. Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells. Kidney Int. 1990;38:417-25 pubmed
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Fabry Z, Waldschmidt M, Hendrickson D, Keiner J, Love Homan L, Takei F, et al. Adhesion molecules on murine brain microvascular endothelial cells: expression and regulation of ICAM-1 and Lgp 55. J Neuroimmunol. 1992;36:1-11 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), eBioscience™
目录# :
14-0541-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent
物种 :
小鼠
克隆 :
YN1/1.7。 4
抗体亚型 :
IgG2b, kappa
储存 :
4° C
描述 :
ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent
别名 :
BB2; CD54; cell surface glycoprotein P3.58; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly-47; major group rhinovirus receptor; MALA-2; MyD10; P3.58; sCD54; soluble CD54
更多信息或购买 :
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产品浏览
- CD54 (ICAM-1) Monoclonal Antibody (eBioKAT-1 (KAT-1, KAT1)), eBioscience™
- CD54 (ICAM-1) Monoclonal Antibody (eBioKAT-1 (KAT-1, KAT1)), eBioscience™
- CD54 (ICAM-1) Monoclonal Antibody (eBioKAT-1 (KAT-1, KAT1)), eBioscience™
- CD54 (ICAM-1) Monoclonal Antibody (HA58), eBioscience™ | 14-0549-80
- CD54 (ICAM-1) Monoclonal Antibody (HA58), eBioscience™ | 14-0549-82
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