产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), eBioscience™
目录 :
14-0541-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
YN1/1.7。 4
反应物种 :
人类, 小鼠
应用 :
免疫组化, 中和反应, 流式细胞仪
更多信息或购买 :
文章摘录数: 40
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 1g
Welsh J, Hoofnagle M, Bamezai S, Oxendine M, Lim L, Hall J, et al. Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis. J Clin Invest. 2019;129:5489-5500 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Edwards R, Kopp S, Ifergan I, Shui J, Kronenberg M, Miller S, et al. Murine Corneal Inflammation and Nerve Damage After Infection With HSV-1 Are Promoted by HVEM and Ameliorated by Immune-Modifying Nanoparticle Therapy. Invest Ophthalmol Vis Sci. 2017;58:282-291 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 5
Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed 出版商
  • 流式细胞仪; 小鼠
Nacer A, Movila A, Sohet F, Girgis N, Gundra U, Loke P, et al. Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier. PLoS Pathog. 2014;10:e1004528 pubmed 出版商
  • 流式细胞仪; 小鼠
Kiesel J, Buchwald Z, Aurora R. Cross-presentation by osteoclasts induces FoxP3 in CD8+ T cells. J Immunol. 2009;182:5477-87 pubmed 出版商
  • 流式细胞仪; 人类; 图 6
Zhang F, Marcus W, Goyal N, Selvaraj P, Springer T, Zhu C. Two-dimensional kinetics regulation of alphaLbeta2-ICAM-1 interaction by conformational changes of the alphaL-inserted domain. J Biol Chem. 2005;280:42207-18 pubmed
Drescher H, Schippers A, Rosenhain S, Gremse F, Bongiovanni L, Bruin A, et al. L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men. Cells. 2020;9: pubmed 出版商
Kanitz A, Syed A, Kaji K, Zavolan M. Conserved regulation of RNA processing in somatic cell reprogramming. BMC Genomics. 2019;20:100 pubmed 出版商
Deloch L, Rückert M, Fietkau R, Frey B, Gaipl U. Low-Dose Radiotherapy Has No Harmful Effects on Key Cells of Healthy Non-Inflamed Joints. Int J Mol Sci. 2018;19: pubmed 出版商
Ward C, Volpe G, Cauchy P, Ptasinska A, Almaghrabi R, Blakemore D, et al. Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming. Cell Rep. 2018;24:1496-1511.e8 pubmed 出版商
Pincha N, Hajam E, Badarinath K, Batta S, Masudi T, Dey R, et al. PAI1 mediates fibroblast-mast cell interactions in skin fibrosis. J Clin Invest. 2018;128:1807-1819 pubmed 出版商
Khoshnejad M, Brenner J, Motley W, Parhiz H, Greineder C, Villa C, et al. Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9. Sci Rep. 2018;8:1760 pubmed 出版商
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed 出版商
Villegas Mendez A, Strangward P, Shaw T, Rajkovic I, Tosevski V, Forman R, et al. Gamma Interferon Mediates Experimental Cerebral Malaria by Signaling within Both the Hematopoietic and Nonhematopoietic Compartments. Infect Immun. 2017;85: pubmed 出版商
Xiong Y, Brinkman C, Famulski K, Mongodin E, Lord C, Hippen K, et al. A robust in vitro model for trans-lymphatic endothelial migration. Sci Rep. 2017;7:1633 pubmed 出版商
Gittens B, Bodkin J, Nourshargh S, Perretti M, Cooper D. Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation. J Immunol. 2017;198:4458-4469 pubmed 出版商
Skopova K, Tomalova B, Kanchev I, Rossmann P, Svedova M, Adkins I, et al. Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis. Infect Immun. 2017;85: pubmed 出版商
Arokiasamy S, Zakian C, Dilliway J, Wang W, Nourshargh S, Voisin M. Endogenous TNFα orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation. Sci Rep. 2017;7:44189 pubmed 出版商
Miyake K, Shiozawa N, Nagao T, Yoshikawa S, Yamanishi Y, Karasuyama H. Trogocytosis of peptide-MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils. Proc Natl Acad Sci U S A. 2017;114:1111-1116 pubmed 出版商
Beard R, Yang X, Meegan J, Overstreet J, Yang C, Elliott J, et al. Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome. Nat Commun. 2016;7:12823 pubmed 出版商
Chantzoura E, Skylaki S, Menendez S, Kim S, Johnsson A, Linnarsson S, et al. Reprogramming Roadblocks Are System Dependent. Stem Cell Reports. 2015;5:350-64 pubmed 出版商
Harding M, Zhang K, Conly J, Kubes P. Neutrophil crawling in capillaries; a novel immune response to Staphylococcus aureus. PLoS Pathog. 2014;10:e1004379 pubmed 出版商
Larsen J, Dall M, Antvorskov J, Weile C, Engkilde K, Josefsen K, et al. Dietary gluten increases natural killer cell cytotoxicity and cytokine secretion. Eur J Immunol. 2014;44:3056-67 pubmed 出版商
O MALLEY J, Skylaki S, Iwabuchi K, Chantzoura E, Ruetz T, Johnsson A, et al. High-resolution analysis with novel cell-surface markers identifies routes to iPS cells. Nature. 2013;499:88-91 pubmed 出版商
Hossain M, Qadri S, Su Y, Liu L. ICAM-1-mediated leukocyte adhesion is critical for the activation of endothelial LSP1. Am J Physiol Cell Physiol. 2013;304:C895-904 pubmed 出版商
Proebstl D, Voisin M, Woodfin A, Whiteford J, D Acquisto F, Jones G, et al. Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med. 2012;209:1219-34 pubmed 出版商
Otsuka A, Kubo M, Honda T, Egawa G, Nakajima S, Tanizaki H, et al. Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity. PLoS ONE. 2011;6:e25538 pubmed 出版商
Birbach A, Eisenbarth D, Kozakowski N, Ladenhauf E, Schmidt Supprian M, Schmid J. Persistent inflammation leads to proliferative neoplasia and loss of smooth muscle cells in a prostate tumor model. Neoplasia. 2011;13:692-703 pubmed
Norling L, Spite M, Yang R, Flower R, Perretti M, Serhan C. Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing. J Immunol. 2011;186:5543-7 pubmed 出版商
Yao L, Baluk P, Feng J, McDonald D. Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways. Am J Pathol. 2010;176:1525-41 pubmed 出版商
Huggins A, Paschalidis N, Flower R, Perretti M, D Acquisto F. Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation. FASEB J. 2009;23:985-96 pubmed 出版商
Sumagin R, Lomakina E, Sarelius I. Leukocyte-endothelial cell interactions are linked to vascular permeability via ICAM-1-mediated signaling. Am J Physiol Heart Circ Physiol. 2008;295:H969-H977 pubmed 出版商
Sumagin R, Brown C, Sarelius I, King M. Microvascular endothelial cells exhibit optimal aspect ratio for minimizing flow resistance. Ann Biomed Eng. 2008;36:580-5 pubmed 出版商
Togbe D, Schofield L, Grau G, Schnyder B, Boissay V, Charron S, et al. Murine cerebral malaria development is independent of toll-like receptor signaling. Am J Pathol. 2007;170:1640-8 pubmed
Zhou J, Friend D, Feldweg A, Daheshia M, Li L, Austen K, et al. Prevention of lipopolysaccharide-induced microangiopathy by gp49B1: evidence for an important role for gp49B1 expression on neutrophils. J Exp Med. 2003;198:1243-51 pubmed
Kumasaka T, Quinlan W, Doyle N, Condon T, Sligh J, Takei F, et al. Role of the intercellular adhesion molecule-1(ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides, anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice. J Clin Invest. 1996;97:2362-9 pubmed
Burns A, Takei F, Doerschuk C. Quantitation of ICAM-1 expression in mouse lung during pneumonia. J Immunol. 1994;153:3189-98 pubmed
Jevnikar A, Wuthrich R, Takei F, Xu H, Brennan D, Glimcher L, et al. Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells. Kidney Int. 1990;38:417-25 pubmed
Fabry Z, Waldschmidt M, Hendrickson D, Keiner J, Love Homan L, Takei F, et al. Adhesion molecules on murine brain microvascular endothelial cells: expression and regulation of ICAM-1 and Lgp 55. J Neuroimmunol. 1992;36:1-11 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD54 (ICAM-1) Monoclonal Antibody (YN1/1.7.4), eBioscience™
目录# :
14-0541-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent
物种 :
小鼠
克隆 :
YN1/1.7。 4
抗体亚型 :
IgG2b, kappa
储存 :
4° C
描述 :
ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Neutralization: Assay-Dependent
别名 :
BB2; CD54; cell surface glycoprotein P3.58; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly-47; major group rhinovirus receptor; MALA-2; MyD10; P3.58; sCD54; soluble CD54
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国