产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD62E (E-selectin) Monoclonal Antibody (P2H3), eBioscience™
目录 :
14-0627-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
P2H3
反应物种 :
人类, 小鼠, pigs
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 6
出版应用/物种/样本/稀释 | 参考文献 |
---|---|
| |
| |
Bevilacqua M, Stengelin S, Gimbrone M, Seed B. Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science. 1989;243:1160-5 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
CD62E (E-selectin) Monoclonal Antibody (P2H3), eBioscience™
目录# :
14-0627-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:500
物种 :
人类, 小鼠
克隆 :
P2H3
抗体亚型 :
IgG1
储存 :
4° C
描述 :
Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes. In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation. This response is immediate and involves a cascade of adhesion receptors. At the endothelial surface members of the selectin and immunoglobulin superfamilies participate in this cascade. Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines. In vitro experiments have shown that IL-1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signaling cascade. E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:500
别名 :
CD62 antigen-like family member E; CD62E; e selectin; Elam; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule; endothelial leukocyte adhesion molecule 1; endothelial leukocyte adhesion molecule I; ESEL; E-selectin; LECAM2; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; RP1-117P20.2; SELE; selectin E; selectin E (endothelial adhesion molecule 1); selectin, endothelial cell
更多信息或购买 :
公司信息
赛默飞世尔
微博分享
关注我们的微博
- 来邦网
- 英文来邦
产品浏览
- CD62E (E-selectin) Monoclonal Antibody (P2H3), eBioscience™ | 14-0627-82
- CD62P (P-Selectin) Monoclonal Antibody (AK-4), eBioscience™ | 14-0628-80
- CD62P (P-Selectin) Monoclonal Antibody (AK-4), eBioscience™ | 14-0628-82
- CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), eBioscience™
- CD62L (L-Selectin) Monoclonal Antibody (DREG-56 (DREG56)), eBioscience™
问题和意见