产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD68 Monoclonal Antibody (KP1), eBioscience™
目录 :
14-0688-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
KP1
反应物种 :
人类, 小鼠, pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, mass cytometry
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 图 6f
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed 出版商
  • 免疫组化; pigs ; 1:100; 图 6h
Fang B, Ren X, Wang Y, Li Z, Zhao L, Zhang M, et al. Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs. Dis Model Mech. 2018;11: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 s7
Chevrier S, Levine J, Zanotelli V, Silina K, Schulz D, Bacac M, et al. An Immune Atlas of Clear Cell Renal Cell Carcinoma. Cell. 2017;169:736-749.e18 pubmed 出版商
  • mass cytometry; 人类; 图 1j
See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 s2b
de Jong R, Paulin N, Lemnitzer P, Viola J, Winter C, Ferraro B, et al. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:312-315 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 1
Chuang T, Guo Y, Seki S, Rosen A, Johanson D, Mandell J, et al. LRP1 expression in microglia is protective during CNS autoimmunity. Acta Neuropathol Commun. 2016;4:68 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:800; 图 1
Liu K, Yang K, Wu B, Chen H, Chen X, Chen X, et al. Tumor-Infiltrating Immune Cells Are Associated With Prognosis of Gastric Cancer. Medicine (Baltimore). 2015;94:e1631 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Prata T, Bonin C, Ferreira A, Padovani C, Fernandes C, Machado A, et al. Local immunosuppression induced by high viral load of human papillomavirus: characterization of cellular phenotypes producing interleukin-10 in cervical neoplastic lesions. Immunology. 2015;146:113-21 pubmed 出版商
Duan F, Guo L, Yang L, Han Y, Thakur A, Nilsson Payant B, et al. Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2. Res Sq. 2020;: pubmed 出版商
Grajchen E, Wouters E, van de Haterd B, Haidar M, Hardonnière K, Dierckx T, et al. CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation. J Neuroinflammation. 2020;17:224 pubmed 出版商
Bowman A, Bogie J, Hendriks J, Haidar M, Belov M, Heeren R, et al. Evaluation of lipid coverage and high spatial resolution MALDI-imaging capabilities of oversampling combined with laser post-ionisation. Anal Bioanal Chem. 2020;412:2277-2289 pubmed 出版商
Kursawe R, Dixit V, Scherer P, Santoro N, Narayan D, Gordillo R, et al. A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents. Diabetes. 2016;65:610-8 pubmed 出版商
Ok Atılgan A, Özdemir B, Akçay E, Ataol Demirkan Ã, Tekindal M, ÖzkardeÅŸ H. Role of tumor-associated macrophages in the Hexim1 and TGFβ/SMAD pathway, and their influence on progression of prostatic adenocarcinoma. Pathol Res Pract. 2016;212:83-92 pubmed 出版商
Song K, Herzog B, Sheng M, Fu J, McDaniel J, Chen H, et al. Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma. Cancer Res. 2013;73:7254-64 pubmed 出版商
Bentley J, Sajjan U, Dzaman M, Jarjour N, Lee W, Gern J, et al. Rhinovirus colocalizes with CD68- and CD11b-positive macrophages following experimental infection in humans. J Allergy Clin Immunol. 2013;132:758-761.e3 pubmed 出版商
Eventov Friedman S, Tchorsh D, Katchman H, Shezen E, Aronovich A, Hecht G, et al. Embryonic pig pancreatic tissue transplantation for the treatment of diabetes. PLoS Med. 2006;3:e215 pubmed
Kunisch E, Fuhrmann R, Roth A, Winter R, Lungershausen W, Kinne R. Macrophage specificity of three anti-CD68 monoclonal antibodies (KP1, EBM11, and PGM1) widely used for immunohistochemistry and flow cytometry. Ann Rheum Dis. 2004;63:774-84 pubmed
Pulford K, Rigney E, Micklem K, Jones M, Stross W, Gatter K, et al. KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections. J Clin Pathol. 1989;42:414-21 pubmed
Horny H, Schaumburg Lever G, Bolz S, Geerts M, Kaiserling E. Use of monoclonal antibody KP1 for identifying normal and neoplastic human mast cells. J Clin Pathol. 1990;43:719-22 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD68 Monoclonal Antibody (KP1), eBioscience™
目录# :
14-0688-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 µg/ml, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
物种 :
人类
克隆 :
KP1
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: 5 µg/ml, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent
别名 :
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国