产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD115 (c-fms) Monoclonal Antibody (AFS98), eBioscience
目录 :
14-1152-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
AFS98
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 中和反应, 流式细胞仪, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 200
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 4a
Seung H, Wröbel J, Wadle C, B xfc hler T, Chiang D, Rettkowski J, et al. P2Y12-dependent activation of hematopoietic stem and progenitor cells promotes emergency hematopoiesis after myocardial infarction. Basic Res Cardiol. 2022;117:16 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6d
Droho S, Cuda C, Perlman H, Lavine J. Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis. Sci Rep. 2021;11:18084 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3c
Sivasubramaniyam T, Yang J, Cheng H, Zyla A, Li A, Besla R, et al. Dj1 deficiency protects against atherosclerosis with anti-inflammatory response in macrophages. Sci Rep. 2021;11:4723 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s5a
Hidalgo Sastre A, Kuebelsbeck L, Jochheim L, Staufer L, Altmayr F, Johannes W, et al. Toll-like receptor 3 expression in myeloid cells is essential for efficient regeneration after acute pancreatitis in mice. Eur J Immunol. 2021;51:1182-1194 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Park M, Kim H, Lee H, Zabel B, Bae Y. Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection. Sci Adv. 2020;6:eaax8820 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s9c
Chu C, Murdock M, Jing D, Won T, Chung H, Kressel A, et al. The microbiota regulate neuronal function and fear extinction learning. Nature. 2019;574:543-548 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:10; 图 s3a
Kobayakawa K, Ohkawa Y, Yoshizaki S, Tamaru T, Saito T, Kijima K, et al. Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. Sci Adv. 2019;5:eaav5086 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 e7b
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a, 2c
Puchner A, Saferding V, Bonelli M, Mikami Y, Hofmann M, Brunner J, et al. Non-classical monocytes as mediators of tissue destruction in arthritis. Ann Rheum Dis. 2018;77:1490-1497 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Baba O, Horie T, Nakao T, Hakuno D, Nakashima Y, Nishi H, et al. MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways. Mol Cell Biol. 2018;38: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Baranska A, Shawket A, Jouve M, Baratin M, Malosse C, Voluzan O, et al. Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal. J Exp Med. 2018;215:1115-1133 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Huang L, Nazarova E, Tan S, Liu Y, Russell D. Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny. J Exp Med. 2018;215:1135-1152 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4a
Metghalchi S, Vandestienne M, Haddad Y, Esposito B, Dairou J, Tedgui A, et al. Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet. PLoS ONE. 2018;13:e0193737 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6a
Westhorpe C, Norman M, Hall P, Snelgrove S, Finsterbusch M, Li A, et al. Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes. Nat Commun. 2018;9:747 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 1a
Hoving L, De Vries M, de Jong R, Katiraei S, Pronk A, Quax P, et al. The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice. Nutrients. 2018;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Kasaai B, Caolo V, Peacock H, Lehoux S, Gomez Perdiguero E, Luttun A, et al. Erythro-myeloid progenitors can differentiate from endothelial cells and modulate embryonic vascular remodeling. Sci Rep. 2017;7:43817 pubmed 出版商
  • 流式细胞仪; 小鼠
de Jong R, Paulin N, Lemnitzer P, Viola J, Winter C, Ferraro B, et al. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:312-315 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4b
Dong L, Yu W, Zheng H, Loh M, Bunting S, Pauly M, et al. Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment. Nature. 2016;539:304-308 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1g
Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, et al. On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver. Nat Med. 2016;22:945-51 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 2
Li Y, Jalili R, Ghahary A. Accelerating skin wound healing by M-CSF through generating SSEA-1 and -3 stem cells in the injured sites. Sci Rep. 2016;6:28979 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Lancaster G, Kammoun H, Kraakman M, Kowalski G, Bruce C, Febbraio M. PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications. Nat Commun. 2016;7:10626 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s5
Scott C, Zheng F, De Baetselier P, Martens L, Saeys Y, De Prijck S, et al. Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells. Nat Commun. 2016;7:10321 pubmed 出版商
  • 流式细胞仪; 小鼠
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed 出版商
  • 流式细胞仪; 小鼠
Cole C, Verdoni A, Ketkar S, Leight E, Russler Germain D, Lamprecht T, et al. PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia. J Clin Invest. 2016;126:85-98 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, et al. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 2015;42:1143-58 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Finisguerra V, Di Conza G, Di Matteo M, Serneels J, Costa S, Thompson A, et al. MET is required for the recruitment of anti-tumoural neutrophils. Nature. 2015;522:349-53 pubmed 出版商
  • 流式细胞仪; 小鼠
Carmi Y, Spitzer M, Linde I, Burt B, Prestwood T, Perlman N, et al. Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity. Nature. 2015;521:99-104 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Krysiak K, Tibbitts J, Shao J, Liu T, Ndonwi M, Walter M. Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells. Exp Hematol. 2015;43:319-30.e10 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Evrard M, Chong S, Devi S, Chew W, Lee B, Poidinger M, et al. Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L-/- reporter mouse by multiphoton intravital microscopy. J Leukoc Biol. 2015;97:611-9 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Lou J, Low Nam S, Kerkvliet J, Hoppe A. Delivery of CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages. J Cell Sci. 2014;127:5228-39 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Becker A, Walcheck B, Bhattacharya D. ADAM17 limits the expression of CSF1R on murine hematopoietic progenitors. Exp Hematol. 2015;43:44-52.e1-3 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:1000; 图 1,5,6,7
Sauter K, Pridans C, Sehgal A, Bain C, Scott C, Moffat L, et al. The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration. PLoS ONE. 2014;9:e105429 pubmed 出版商
  • 流式细胞仪; 人类
Zhu Y, Knolhoff B, Meyer M, Nywening T, West B, Luo J, et al. CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Cancer Res. 2014;74:5057-69 pubmed 出版商
  • 抑制或激活实验; 小鼠; 5 ug/ml
Sheng K, Herrero L, Taylor A, Hapel A, Mahalingam S. IL-3 and CSF-1 interact to promote generation of CD11c+ IL-10-producing macrophages. PLoS ONE. 2014;9:e95208 pubmed 出版商
  • 流式细胞仪; 小鼠
Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, et al. TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS Pathog. 2014;10:e1003900 pubmed 出版商
  • 流式细胞仪; 小鼠; 2 ug/ml; 图 s10
Cho J, Guo Y, Ramos R, Hebroni F, Plaisier S, Xuan C, et al. Neutrophil-derived IL-1? is sufficient for abscess formation in immunity against Staphylococcus aureus in mice. PLoS Pathog. 2012;8:e1003047 pubmed 出版商
  • 流式细胞仪; 小鼠
Qian B, Li J, Zhang H, Kitamura T, Zhang J, Campion L, et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature. 2011;475:222-5 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Waskow C, Liu K, Darrasse Jèze G, Guermonprez P, Ginhoux F, Merad M, et al. The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues. Nat Immunol. 2008;9:676-83 pubmed 出版商
Zhao T, Liu S, Ding X, Johnson E, Hanna N, Singh K, et al. Lysosomal acid lipase, CSF1R, and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells. JCI Insight. 2022;7: pubmed 出版商
Yan Q, Gao H, Yao Q, Ling K, Xiao G. Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling. J Biol Chem. 2022;298:101639 pubmed 出版商
Awida Z, Bachar A, Saed H, Gorodov A, Ben Califa N, Ibrahim M, et al. The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in Mice. Int J Mol Sci. 2021;23: pubmed 出版商
Oladiran O, Shi X, Fournier S, Zhang J. CX3CR1 But Not CCR2 Expression Is Required for the Development of Autoimmune Peripheral Neuropathy in Mice. Front Immunol. 2021;12:720733 pubmed 出版商
Fu J, Shih L, Yen T. HOXA11 plays critical roles in disease progression and response to cytarabine in AML. Oncol Rep. 2021;46: pubmed 出版商
Serrano López J, Hegde S, Kumar S, Serrano J, Fang J, Wellendorf A, et al. Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics. elife. 2021;10: pubmed 出版商
Oladiran O, Shi X, Yang M, Fournier S, Zhang J. Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy. J Neuroinflammation. 2021;18:77 pubmed 出版商
Wieghofer P, Hagemeyer N, Sankowski R, Schlecht A, Staszewski O, Amann L, et al. Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling. EMBO J. 2021;40:e105123 pubmed 出版商
Wesolowski R, Kowenz Leutz E, Zimmermann K, Dörr D, Hofstätter M, Slany R, et al. Myeloid transformation by MLL-ENL depends strictly on C/EBP. Life Sci Alliance. 2021;4: pubmed 出版商
Christofi M, Le Sommer S, Molzer C, Klaska I, Kuffova L, Forrester J. Low-dose 2-deoxy glucose stabilises tolerogenic dendritic cells and generates potent in vivo immunosuppressive effects. Cell Mol Life Sci. 2021;78:2857-2876 pubmed 出版商
Consiglio C, Gollnick S. Androgen Receptor Signaling Positively Regulates Monocytic Development. Front Immunol. 2020;11:519383 pubmed 出版商
Lechuga Vieco A, Latorre Pellicer A, Johnston I, Prota G, Gileadi U, Justo Méndez R, et al. Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics. Sci Adv. 2020;6:eaba5345 pubmed 出版商
Xiao J, Wang C, Yao J, Alippe Y, Yang T, Kress D, et al. Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells. PLoS Biol. 2020;18:e3000807 pubmed 出版商
Wang S, Li R, Ng T, Luthria G, Oudin M, Prytyskach M, et al. Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy. Sci Adv. 2020;6:eaaz8521 pubmed 出版商
Boeck M, Thien A, Wolf J, Hagemeyer N, Laich Y, Yusuf D, et al. Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model. Glia. 2020;68:1859-1873 pubmed 出版商
Zhang J, Supakorndej T, Krambs J, Rao M, Abou Ezzi G, Ye R, et al. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129:2920-2931 pubmed 出版商
Paudel S, Baral P, Ghimire L, Bergeron S, Jin L, De Corte J, et al. CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3. Blood. 2019;: pubmed 出版商
Ni K, Gill A, Cao D, Koike K, Schweitzer K, Garantziotis S, et al. Intravascular heavy chain-modification of hyaluronan during endotoxic shock. Biochem Biophys Rep. 2019;17:114-121 pubmed 出版商
Thomas D, Doran A, Fotakis P, Westerterp M, Antonson P, Jiang H, et al. LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux. Cell Rep. 2018;25:3774-3785.e4 pubmed 出版商
Percin G, Eitler J, Kranz A, Fu J, Pollard J, Naumann R, et al. CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages. Nat Commun. 2018;9:5279 pubmed 出版商
Tong Y, Zhou L, Yang L, Guo P, Cao Y, Qin F, et al. Concomitant type I IFN and M-CSF signaling reprograms monocyte differentiation and drives pro-tumoral arginase production. EBioMedicine. 2019;39:132-144 pubmed 出版商
Plantamura E, Dzutsev A, Chamaillard M, Djebali S, Moudombi L, Boucinha L, et al. MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype. Proc Natl Acad Sci U S A. 2018;115:10404-10409 pubmed 出版商
Matesanz N, Nikolic I, Leiva M, Pulgarín Alfaro M, Santamans A, Bernardo E, et al. p38α blocks brown adipose tissue thermogenesis through p38δ inhibition. PLoS Biol. 2018;16:e2004455 pubmed 出版商
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Petvises S, Periasamy P, O Neill H. MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis. BMC Immunol. 2018;19:21 pubmed 出版商
Kirkling M, Cytlak U, Lau C, Lewis K, Resteu A, Khodadadi Jamayran A, et al. Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells. Cell Rep. 2018;23:3658-3672.e6 pubmed 出版商
Tang J, Frey J, Wilson C, Moncada Pazos A, Levet C, Freeman M, et al. Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation. Mol Cell Biol. 2018;38: pubmed 出版商
Hsiao H, Fernandez R, Tanaka S, Li W, Spahn J, Chiu S, et al. Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β. J Clin Invest. 2018;128:2833-2847 pubmed 出版商
Jin X, Liu L, Zhang Y, Xiang Y, Yin G, Lu Y, et al. Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling. J Diabetes Res. 2018;2018:2527406 pubmed 出版商
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Wang J, Hodes G, Zhang H, Zhang S, Zhao W, Golden S, et al. Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice. Nat Commun. 2018;9:477 pubmed 出版商
Czimmerer Z, Dániel B, Horvath A, Rückerl D, Nagy G, Kiss M, et al. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity. 2018;48:75-90.e6 pubmed 出版商
Hogstad B, Berres M, Chakraborty R, Tang J, Bigenwald C, Serasinghe M, et al. RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions. J Exp Med. 2018;215:319-336 pubmed 出版商
Menard C, Pfau M, Hodes G, Kana V, Wang V, Bouchard S, et al. Social stress induces neurovascular pathology promoting depression. Nat Neurosci. 2017;20:1752-1760 pubmed 出版商
Caballero S, Kent D, Sengupta N, Li Calzi S, Shaw L, Beli E, et al. Bone Marrow-Derived Cell Recruitment to the Neurosensory Retina and Retinal Pigment Epithelial Cell Layer Following Subthreshold Retinal Phototherapy. Invest Ophthalmol Vis Sci. 2017;58:5164-5176 pubmed 出版商
Burns K, Thomas S, Hamilton K, Young S, Cook D, Korach K. Early Endometriosis in Females Is Directed by Immune-Mediated Estrogen Receptor α and IL-6 Cross-Talk. Endocrinology. 2018;159:103-118 pubmed 出版商
Ebina Shibuya R, Matsumoto M, Kuwahara M, Jang K, Sugai M, Ito Y, et al. Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis. J Biol Chem. 2017;292:18098-18112 pubmed 出版商
Cole C, Russler Germain D, Ketkar S, Verdoni A, Smith A, Bangert C, et al. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies. J Clin Invest. 2017;127:3657-3674 pubmed 出版商
Gilboa D, Haim Ohana Y, Deshet Unger N, Ben Califa N, Hiram Bab S, Reuveni D, et al. Erythropoietin enhances Kupffer cell number and activity in the challenged liver. Sci Rep. 2017;7:10379 pubmed 出版商
Llewellyn R, Thomas K, Gutknecht M, Bouton A. The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state. J Leukoc Biol. 2017;102:1069-1080 pubmed 出版商
Neudecker V, Haneklaus M, Jensen O, Khailova L, Masterson J, Tye H, et al. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. J Exp Med. 2017;214:1737-1752 pubmed 出版商
Liu J, Xiao C, Wang H, Xue Y, Dong D, Lin C, et al. Local Group 2 Innate Lymphoid Cells Promote Corneal Regeneration after Epithelial Abrasion. Am J Pathol. 2017;187:1313-1326 pubmed 出版商
Wall V, Barnhart S, Kramer F, Kanter J, Vivekanandan Giri A, Pennathur S, et al. Inflammatory stimuli induce acyl-CoA thioesterase 7 and remodeling of phospholipids containing unsaturated long (≥C20)-acyl chains in macrophages. J Lipid Res. 2017;58:1174-1185 pubmed 出版商
Liron T, Raphael B, Hiram Bab S, Bab I, Gabet Y. Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes. J Cell Physiol. 2018;233:371-377 pubmed 出版商
Liu J, Xue Y, Dong D, Xiao C, Lin C, Wang H, et al. CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion. Mucosal Immunol. 2017;10:1145-1159 pubmed 出版商
Kandalla P, Sarrazin S, Molawi K, Berruyer C, Redelberger D, Favel A, et al. M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation. J Exp Med. 2016;213:2269-2279 pubmed
Wu X, Briseño C, Durai V, Albring J, Haldar M, Bagadia P, et al. Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells. J Exp Med. 2016;213:2553-2565 pubmed
Henry E, Sy C, Inclan Rico J, Espinosa V, Ghanny S, Dwyer D, et al. Carbonic anhydrase enzymes regulate mast cell-mediated inflammation. J Exp Med. 2016;213:1663-73 pubmed 出版商
Al Sadoun H, Burgess M, Hentges K, Mace K. Enforced Expression of Hoxa3 Inhibits Classical and Promotes Alternative Activation of Macrophages In Vitro and In Vivo. J Immunol. 2016;197:872-84 pubmed 出版商
Ho S, Zhang W, Tan N, Khatoo M, Suter M, Tripathi S, et al. The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells. Immunity. 2016;44:1177-89 pubmed 出版商
Hollmen M, Karaman S, Schwager S, Lisibach A, Christiansen A, Maksimow M, et al. G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer. Oncoimmunology. 2016;5:e1115177 pubmed
Wang T, Wang Z, Yang P, Xia L, Zhou M, Wang S, et al. PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice. Cell Death Dis. 2016;7:e2176 pubmed 出版商
Hey Y, Tan J, O Neill H. Redefining Myeloid Cell Subsets in Murine Spleen. Front Immunol. 2015;6:652 pubmed 出版商
Mandl M, Drechsler M, Jansen Y, Neideck C, Noels H, Faussner A, et al. Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation. PLoS ONE. 2015;10:e0134176 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD115 (c-fms) Monoclonal Antibody (AFS98), eBioscience
目录# :
14-1152-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 1 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Neutralization: Assay-Dependent, Western Blot: Assay-Dependent
物种 :
小鼠
克隆 :
AFS98
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
CSF1R (FMS) is involved in the production, differentiation, and function of macrophages, and is implicated in promyelocytic leukemias. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. CSF1R is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and plays an important role in innate immunity and in inflammatory processes. The first intron of the CSF1R gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Mutations in the CSF1R gene have been associated with a predisposition to myeloid malignancy.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Neutralization: Assay-Dependent, Western Blot: Assay-Dependent
别名 :
AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; CSFIR; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; FMS; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; protein-tyrosine kinase; proto-oncogene c-Fms; proto-oncogene fms
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国