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NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
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Ki-67 Monoclonal Antibody (SolA15), eBioscience™
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食蟹猴, 人类, 小鼠, 大鼠,
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, mass cytometry
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文章摘录数: 204
  • 免疫组化; 小鼠; 1:200; 图 3b
Ide S, Yahara Y, Kobayashi Y, Strausser S, Ide K, Watwe A, et al. Yolk-sac-derived macrophages progressively expand in the mouse kidney with age. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 8i
Stebegg M, Bignon A, Hill D, Silva Cayetano A, Krueger C, Vanderleyden I, et al. Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:100; 图 3f
Pein M, Insua Rodríguez J, Hongu T, Riedel A, Meier J, Wiedmann L, et al. Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs. Nat Commun. 2020;11:1494 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6s1a
Kumar A, Chamoto K, Chowdhury P, Honjo T. Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 3b
Dause T, KIRBY E. Poor Concordance of Floxed Sequence Recombination in Single Neural Stem Cells: Implications for Cell Autonomous Studies. Eneuro. 2020;7: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3b
Park M, Kim H, Lee H, Zabel B, Bae Y. Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection. Sci Adv. 2020;6:eaax8820 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s7c, s7d
Parisi G, Saco J, Salazar F, Tsoi J, Krystofinski P, Puig Saus C, et al. Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist. Nat Commun. 2020;11:660 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1j
Bell L, Lenhart A, Rosenwald A, Monoranu C, Berberich Siebelt F. Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells. Front Immunol. 2019;10:3090 pubmed 出版商
  • mass cytometry; 小鼠; 0.75 ug/ml; 图 5d
Guo C, Allen B, Hiam K, Dodd D, Van Treuren W, Higginbottom S, et al. Depletion of microbiome-derived molecules in the host using Clostridium genetics. Science. 2019;366: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s6a, s6b
Pei G, Yao Y, Yang Q, Wang M, Wang Y, Wu J, et al. Lymphangiogenesis in kidney and lymph node mediates renal inflammation and fibrosis. Sci Adv. 2019;5:eaaw5075 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 1b
Prior N, Hindley C, Rost F, Meléndez E, Lau W, Gottgens B, et al. Lgr5+ stem and progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool. Development. 2019;146: pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:500; 图 s1c
Shen M, Wang F, Li M, Sah N, Stockton M, Tidei J, et al. Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice. Nat Neurosci. 2019;22:386-400 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3e
Takemoto Y, Inaba S, Zhang L, Tsujikawa K, Uezumi A, Fukada S. Implication of basal lamina dependency in survival of Nrf2-null muscle stem cells via an antioxidative-independent mechanism. J Cell Physiol. 2019;234:1689-1698 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3b
Kiang L, Ross B, Yao J, Shanmugam S, Andrews C, Hansen S, et al. Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment. Invest Ophthalmol Vis Sci. 2018;59:3767-3778 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3c
Baens M, Stirparo R, Lampi Y, Verbeke D, Vandepoel R, Cools J, et al. Malt1 self-cleavage is critical for regulatory T cell homeostasis and anti-tumor immunity in mice. Eur J Immunol. 2018;48:1728-1738 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s5a
  • 免疫组化-石蜡切片; 小鼠; 图 s5a
Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2c
Liu T, Kong W, Tang X, Xu M, Wang Q, Zhang B, et al. The transcription factor Zfp90 regulates the self-renewal and differentiation of hematopoietic stem cells. Cell Death Dis. 2018;9:677 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7a
Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine T, et al. Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression. J Clin Invest. 2018;128:2487-2499 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Huang L, Nazarova E, Tan S, Liu Y, Russell D. Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny. J Exp Med. 2018;215:1135-1152 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Ellestad K, Thangavelu G, Haile Y, Lin J, Boon L, Anderson C. Prior to Peripheral Tolerance, Newly Generated CD4 T Cells Maintain Dangerous Autoimmune Potential: Fas- and Perforin-Independent Autoimmunity Controlled by Programmed Death-1. Front Immunol. 2018;9:12 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Wasiuk A, Testa J, Weidlick J, Sisson C, Vitale L, Widger J, et al. CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy. J Immunol. 2017;199:4110-4123 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 3f
Guo H, Kazadaeva Y, Ortega F, Manjunath N, Desai T. Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017;430:214-223 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5e
Nikolaidis N, Noel J, Pitstick L, Gardner J, Uehara Y, Wu H, et al. Mitogenic stimulation accelerates influenza-induced mortality by increasing susceptibility of alveolar type II cells to infection. Proc Natl Acad Sci U S A. 2017;114:E6613-E6622 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3d
Lee S, Park H, Suh Y, Yoon E, Kim J, Jang W, et al. Inhibition of acute lethal pulmonary inflammation by the IDO-AhR pathway. Proc Natl Acad Sci U S A. 2017;114:E5881-E5890 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 8c
Barazzuol L, Ju L, Jeggo P. A coordinated DNA damage response promotes adult quiescent neural stem cell activation. PLoS Biol. 2017;15:e2001264 pubmed 出版商
  • 流式细胞仪; 大鼠; 图 1f
Tuncel J, Haag S, Holmdahl R. MHC class II alleles associated with Th1 rather than Th17 type immunity drive the onset of early arthritis in a rat model of rheumatoid arthritis. Eur J Immunol. 2017;47:563-574 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Seifert A, Zeng S, Zhang J, Kim T, Cohen N, Beckman M, et al. PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors. Clin Cancer Res. 2017;23:454-465 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400; 图 s1c
Ohs I, Van Den Broek M, Nussbaum K, MUNZ C, Arnold S, Quezada S, et al. Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun. 2016;7:13708 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Ladle B, Li K, Phillips M, Pucsek A, Haile A, Powell J, et al. De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation. Proc Natl Acad Sci U S A. 2016;113:10631-6 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 表 1
  • 免疫细胞化学; 小鼠; 1:100; 表 1
Jackson Jones L, Duncan S, Magalhaes M, Campbell S, Maizels R, McSorley H, et al. Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nat Commun. 2016;7:12651 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Cheng H, Gaddis D, Wu R, McSkimming C, Haynes L, Taylor A, et al. Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. J Clin Invest. 2016;126:3236-46 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 8b
Hwang S, Cobb D, Bhadra R, Youngblood B, Khan I. Blimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis. J Exp Med. 2016;213:1799-818 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500
Dutta A, Le Magnen C, Mitrofanova A, Ouyang X, Califano A, Abate Shen C. Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science. 2016;352:1576-80 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 s4d
Fox R, Lytle N, Jaquish D, Park F, Ito T, Bajaj J, et al. Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature. 2016;534:407-411 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 1d
Sigl V, Owusu Boaitey K, Joshi P, Kavirayani A, Wirnsberger G, Novatchkova M, et al. RANKL/RANK control Brca1 mutation- . Cell Res. 2016;26:761-74 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 4d
Schulz A, Büttner R, Hagel C, Baader S, Kluwe L, Salamon J, et al. The importance of nerve microenvironment for schwannoma development. Acta Neuropathol. 2016;132:289-307 pubmed 出版商
  • 免疫组化; 人类
Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, et al. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. Nat Commun. 2016;7:11385 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 s14a
Lombardi R, Chen S, Ruggiero A, Gurha P, Czernuszewicz G, Willerson J, et al. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016;119:41-54 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Kabat A, Harrison O, Riffelmacher T, Moghaddam A, Pearson C, Laing A, et al. The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. elife. 2016;5:e12444 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 1
Lanza D, Dawson E, Rao P, Heaney J. Misexpression of cyclin D1 in embryonic germ cells promotes testicular teratoma initiation. Cell Cycle. 2016;15:919-30 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5b
Chandrasekaran U, Yi W, Gupta S, Weng C, Giannopoulou E, Chinenov Y, et al. Regulation of Effector Treg Cells in Murine Lupus. Arthritis Rheumatol. 2016;68:1454-66 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1c
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Moretto M, Khan I. IL-21 Is Important for Induction of KLRG1+ Effector CD8 T Cells during Acute Intracellular Infection. J Immunol. 2016;196:375-84 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 3e
Barazzuol L, Rickett N, Ju L, Jeggo P. Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells. J Cell Sci. 2015;128:3597-606 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50; 图 s8b
Kimura W, Xiao F, Canseco D, Muralidhar S, Thet S, Zhang H, et al. Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart. Nature. 2015;523:226-30 pubmed 出版商
  • 流式细胞仪; 小鼠
Evonuk K, Baker B, Doyle R, Moseley C, Sestero C, Johnston B, et al. Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination. J Immunol. 2015;195:450-463 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Moguche A, Shafiani S, Clemons C, Larson R, Dinh C, Higdon L, et al. ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis. J Exp Med. 2015;212:715-28 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Charlton J, Tsoukatou D, Mamalaki C, Chatzidakis I. Programmed death 1 regulates memory phenotype CD4 T cell accumulation, inhibits expansion of the effector memory phenotype subset and modulates production of effector cytokines. PLoS ONE. 2015;10:e0119200 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Povinelli B, Kokolus K, Eng J, Dougher C, Curtin L, Capitano M, et al. Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells. PLoS ONE. 2015;10:e0120078 pubmed 出版商
  • 流式细胞仪; 小鼠
Stoycheva D, Deiser K, Stärck L, Nishanth G, Schlüter D, Uckert W, et al. IFN-γ regulates CD8+ memory T cell differentiation and survival in response to weak, but not strong, TCR signals. J Immunol. 2015;194:553-9 pubmed 出版商
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Mouchacca P, Chasson L, Frick M, Foray C, Schmitt Verhulst A, Boyer C. Visualization of granzyme B-expressing CD8 T cells during primary and secondary immune responses to Listeria monocytogenes. Immunology. 2015;145:24-33 pubmed 出版商
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ZasÅ‚ona Z, Przybranowski S, Wilke C, Van Rooijen N, Teitz Tennenbaum S, Osterholzer J, et al. Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma. J Immunol. 2014;193:4245-53 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100
Meraz I, Savage D, Segura Ibarra V, Li J, Rhudy J, Gu J, et al. Adjuvant cationic liposomes presenting MPL and IL-12 induce cell death, suppress tumor growth, and alter the cellular phenotype of tumors in a murine model of breast cancer. Mol Pharm. 2014;11:3484-91 pubmed 出版商
  • 流式细胞仪; 小鼠
Denton A, Roberts E, Linterman M, Fearon D. Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells. Proc Natl Acad Sci U S A. 2014;111:12139-44 pubmed 出版商
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Cowan J, McCarthy N, Parnell S, White A, Bacon A, Serge A, et al. Differential requirement for CCR4 and CCR7 during the development of innate and adaptive ??T cells in the adult thymus. J Immunol. 2014;193:1204-12 pubmed 出版商
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Mizoguchi T, Pinho S, Ahmed J, Kunisaki Y, Hanoun M, Mendelson A, et al. Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development. Dev Cell. 2014;29:340-9 pubmed 出版商
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Meraz I, Hearnden C, Liu X, Yang M, Williams L, Savage D, et al. Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes. PLoS ONE. 2014;9:e94703 pubmed 出版商
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Joedicke J, Dietze K, Zelinskyy G, Dittmer U. The phenotype and activation status of regulatory T cells during Friend retrovirus infection. Virol Sin. 2014;29:48-60 pubmed 出版商
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Cavnar M, Zeng S, Kim T, Sorenson E, Ocuin L, Balachandran V, et al. KIT oncogene inhibition drives intratumoral macrophage M2 polarization. J Exp Med. 2013;210:2873-86 pubmed 出版商
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Povinelli B, Nemeth M. Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor. Stem Cells. 2014;32:105-15 pubmed 出版商
Mei Y, Han X, Liu Y, Yang J, Sumagin R, Ji P. Diaphanous-related formin mDia2 regulates beta2 integrins to control hematopoietic stem and progenitor cell engraftment. Nat Commun. 2020;11:3172 pubmed 出版商
Hermanova I, Z iga Garc a P, Caro Maldonado A, Fernandez Ruiz S, Salvador F, Mart n Mart n N, et al. Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer. J Exp Med. 2020;217: pubmed 出版商
Vanderleyden I, Fra Bido S, Innocentin S, Stebegg M, Okkenhaug H, Evans Bailey N, et al. Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5. Cell Rep. 2020;30:611-619.e4 pubmed 出版商
Chen C, Yu W, Tober J, Gao P, He B, Lee K, et al. Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells. Cell Rep. 2019;29:4200-4211.e7 pubmed 出版商
Wang L, Shen E, Luo L, Rabe H, Wang Q, Yin J, et al. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor. Cell Rep. 2019;29:1848-1861.e6 pubmed 出版商
Frodermann V, Rohde D, Courties G, Severe N, Schloss M, Amatullah H, et al. Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells. Nat Med. 2019;25:1761-1771 pubmed 出版商
Pietila M, Sahgal P, Peuhu E, Jäntti N, Paatero I, Närvä E, et al. SORLA regulates endosomal trafficking and oncogenic fitness of HER2. Nat Commun. 2019;10:2340 pubmed 出版商
Moon H, Zhu J, Donahue L, Choi E, White A. Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress. Nat Commun. 2019;10:2225 pubmed 出版商
Choi H, Deng J, Li S, Silk T, Dong L, Brea E, et al. Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer. Cell Rep. 2019;27:806-819.e5 pubmed 出版商
Zhou L, Chu C, Teng F, Bessman N, Goc J, Santosa E, et al. Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2. Nature. 2019;568:405-409 pubmed 出版商
Castro Dopico T, Dennison T, Ferdinand J, Mathews R, FLEMING A, Clift D, et al. Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis. Immunity. 2019;50:1099-1114.e10 pubmed 出版商
Silva H, Bafica A, Rodrigues Luiz G, Chi J, Santos P, Reis B, et al. Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges. J Exp Med. 2019;216:786-806 pubmed 出版商
Tan D, Li Y, Yang C, Li J, Tan S, Chin D, et al. PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells. Cell Rep. 2019;26:2316-2328.e6 pubmed 出版商
Arimura N, Dewa K, Okada M, Yanagawa Y, Taya S, Hoshino M. Comprehensive and cell-type-based characterization of the dorsal midbrain during development. Genes Cells. 2019;24:41-59 pubmed 出版商
Zhang Y, Riquier Brison A, Liu T, Huang Y, Carlson N, Peti Peterdi J, et al. Genetic Deletion of P2Y2 Receptor Offers Long-Term (5 Months) Protection Against Lithium-Induced Polyuria, Natriuresis, Kaliuresis, and Collecting Duct Remodeling and Cell Proliferation. Front Physiol. 2018;9:1765 pubmed 出版商
Commerford C, Dieterich L, He Y, Hell T, Montoya Zegarra J, Noerrelykke S, et al. Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes. Cell Rep. 2018;25:3554-3563.e4 pubmed 出版商
Zhang W, Li Q, Li D, Li J, Aki D, Liu Y. The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation. J Exp Med. 2018;215:3180-3193 pubmed 出版商
Glal D, Sudhakar J, Lu H, Liu M, Chiang H, Liu Y, et al. ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases. Front Immunol. 2018;9:2522 pubmed 出版商
Shi H, Liu C, Tan H, Li Y, Nguyen T, Dhungana Y, et al. Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity. Immunity. 2018;49:899-914.e6 pubmed 出版商
Koren E, Yosefzon Y, Ankawa R, Soteriou D, Jacob A, Nevelsky A, et al. ARTS mediates apoptosis and regeneration of the intestinal stem cell niche. Nat Commun. 2018;9:4582 pubmed 出版商
Stratton J, Assinck P, Sinha S, Kumar R, Moulson A, Patrick N, et al. Factors Within the Endoneurial Microenvironment Act to Suppress Tumorigenesis of MPNST. Front Cell Neurosci. 2018;12:356 pubmed 出版商
Bertram K, Narendran N, Tailor P, Jablonski C, Leonard C, Irvine E, et al. 17-DMAG regulates p21 expression to induce chondrogenesis in vitro and in vivo. Dis Model Mech. 2018;11: pubmed 出版商
Yu Z, Jiang K, Xu Z, Huang H, Qian N, Lu Z, et al. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration. Cell Stem Cell. 2018;23:487-500.e6 pubmed 出版商
Yu X, Teng X, Wang F, Zheng Y, Qu G, Zhou Y, et al. Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome. J Exp Med. 2018;215:2463-2476 pubmed 出版商
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产品类型 :
产品名称 :
Ki-67 Monoclonal Antibody (SolA15), eBioscience™
目录# :
规格 :
价格(美元) :
克隆性 :
纯度 :
宿主 :
反应物种 :
Canine, Cynomolgus Monkey, Human, Mouse, Non-human primate, Rat
应用 :
Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Frozen): 5 µg/mL, Immunohistochemistry (Paraffin): 2.5-5 µg/mL
物种 :
Canine, Cynomolgus Monkey, Human, Mouse, Non-human primate, Rat
克隆 :
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
格式 :
应用w/稀释 :
Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Frozen): 5 µg/mL, Immunohistochemistry (Paraffin): 2.5-5 µg/mL
别名 :
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05
更多信息或购买 :
公司总部: 美国