产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD328 (Siglec7) Monoclonal Antibody (eBioQA79 (QA79)), eBioscience™
目录 :
14-5759-37
规格 :
2毫克
价格 :
美国1372
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
eBioQA79(QA79)
反应物种 :
人类
应用 :
免疫沉淀, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 2
参考文献
Kawasaki N, Rillahan C, Cheng T, Van Rhijn I, Macauley M, Moody D, et al. Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation. J Immunol. 2014;193:1560-6 pubmed 出版商
Rillahan C, Schwartz E, Rademacher C, McBride R, Rangarajan J, Fokin V, et al. On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7. ACS Chem Biol. 2013;8:1417-22 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD328 (Siglec7) Monoclonal Antibody (eBioQA79 (QA79)), eBioscience™
目录# :
14-5759-37
规格 :
2毫克
价格 :
美国1372
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 0.5 µg/test, Immunoprecipitation: Assay-Dependent
物种 :
人类
克隆 :
eBioQA79(QA79)
抗体亚型 :
IgG1
储存 :
4° C
描述 :
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test, Immunoprecipitation: Assay-Dependent
别名 :
Adhesion inhibitory receptor molecule 1; adhesion inhibitory receptor molecule 1, siglec-7; AIRM1; AIRM-1; CD328; CDw328; D-siglec; p75; p75/ AIRM-1; p75/AIRM1; QA79; QA79 membrane protein; sialic acid binding Ig like lectin 7; sialic acid binding Ig-like lectin 7; sialic acid binding immunoglobulin-like lectin 7; sialic acid-binding Ig-like lectin 7; Siglec; SIGLEC19P; SIGLEC7; SIGLEC-7; SIGLECP2
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国