产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
FOXP3 Monoclonal Antibody (FJK-16s), eBioscience
目录 :
14-5773-37
规格 :
2毫克
价格 :
美国1234
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
FJK-16s
反应物种 :
, 小鼠, 大鼠, , , pigs ,
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 649
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 1b
Kim M, Borcherding N, Ahmed K, Voigt A, Vishwakarma A, Kolb R, et al. CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. Nat Commun. 2021;12:5764 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100
Liu H, Pedros C, Kong K, Canonigo Balancio A, Xue W, Altman A. Leveraging the Treg-intrinsic CTLA4-PKCη signaling pathway for cancer immunotherapy. J Immunother Cancer. 2021;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:40; 图 3f
Lacy M, Burger C, Shami A, Ahmadsei M, Winkels H, Nitz K, et al. Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease. Nat Commun. 2021;12:3754 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s3b
Kemp S, Carpenter E, Steele N, Donahue K, Nwosu Z, Pacheco A, et al. Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1. Cancer Res. 2021;81:4305-4318 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 2c
Zhang S, Li L, Xie D, Reddy S, Sleasman J, Ma L, et al. Regulation of Intrinsic and Bystander T Follicular Helper Cell Differentiation and Autoimmunity by Tsc1. Front Immunol. 2021;12:620437 pubmed 出版商
  • 流式细胞仪; 小鼠
Jhala G, Selck C, Chee J, Kwong C, Pappas E, Thomas H, et al. Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice. Front Immunol. 2021;12:645817 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:50; 图 7a
Borges P, Waclawiak I, Georgii J, Fraga Junior V, Barros J, Lemos F, et al. Adenosine Diphosphate Improves Wound Healing in Diabetic Mice Through P2Y12 Receptor Activation. Front Immunol. 2021;12:651740 pubmed 出版商
  • 流式细胞仪; 小鼠
Nian Y, Iske J, Maenosono R, Minami K, Heinbokel T, Quante M, et al. Targeting age-specific changes in CD4+ T cell metabolism ameliorates alloimmune responses and prolongs graft survival. Aging Cell. 2021;20:e13299 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:50; 图 s17b
Break T, Oikonomou V, Dutzan N, Desai J, Swidergall M, Freiwald T, et al. Aberrant type 1 immunity drives susceptibility to mucosal fungal infections. Science. 2021;371: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Zhao L, Hu S, Davila M, Yang J, Lin Y, Albanese J, et al. Coordinated co-migration of CCR10+ antibody-producing B cells with helper T cells for colonic homeostatic regulation. Mucosal Immunol. 2021;14:420-430 pubmed 出版商
  • 流式细胞仪; 马; 1:10; 图 1
Piszczatowska K, Przybylska D, Sikora E, Mosieniak G. Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells. Antioxidants (Basel). 2020;9: pubmed 出版商
  • 流式细胞仪; 马; 1:10; 图 1
Yasuoka M, Monteiro B, Fantinato Neto P, Paiano R, Fantoni D, Otsuki D, et al. Transient Pulmonary Artery Hypertension in Holstein Neonate Calves. Animals (Basel). 2020;10: pubmed 出版商
  • 流式细胞仪; 马; 1:10; 图 1
Zhang Z, Zheng Q, Liu Y, Sun L, Han P, Wang R, et al. Human CD133-positive hematopoietic progenitor cells enhance the malignancy of breast cancer cells. BMC Cancer. 2020;20:1158 pubmed 出版商
  • 流式细胞仪; 马; 1:10; 图 1
Witkowska Piłaszewicz O, Pingwara R, Winnicka A. The Effect of Physical Training on Peripheral Blood Mononuclear Cell Ex Vivo Proliferation, Differentiation, Activity, and Reactive Oxygen Species Production in Racehorses. Antioxidants (Basel). 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s6-2
Jensen I, Jensen S, Sjaastad F, Gibson Corley K, Dileepan T, Griffith T, et al. Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠
Myers D, Abram C, Wildes D, Belwafa A, Welsh A, Schulze C, et al. Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity. Front Immunol. 2020;11:576310 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100
Fernandes R, Li C, Wang G, Yang X, Savvides C, Glassman C, et al. Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4b
Svensson M, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody K, et al. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Sci Adv. 2020;6:eaba4353 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 2j
Stebegg M, Bignon A, Hill D, Silva Cayetano A, Krueger C, Vanderleyden I, et al. Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5c, 5d
Zhang S, Liang W, Luo L, Sun S, Wang F. The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology. BMC Biol. 2020;18:29 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
Lawenius L, Scheffler J, Gustafsson K, Henning P, Nilsson K, Colldén H, et al. Pasteurized Akkermansia muciniphila protects from fat mass gain but not from bone loss. Am J Physiol Endocrinol Metab. 2020;318:E480-E491 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6s1
Canel M, Taggart D, Sims A, Lonergan D, Waizenegger I, Serrels A. T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. elife. 2020;9: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s4p
  • 流式细胞仪; 小鼠; 1:100; 图 4b
Li A, Herbst R, Canner D, Schenkel J, Smith O, Kim J, et al. IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development. Cell Rep. 2019;29:2998-3008.e8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4c
Hang S, Paik D, Yao L, Kim E, Jamma T, Lu J, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019;576:143-148 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2j
Wang L, Shen E, Luo L, Rabe H, Wang Q, Yin J, et al. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor. Cell Rep. 2019;29:1848-1861.e6 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 e8b
Alspach E, Lussier D, Miceli A, Kizhvatov I, DuPage M, Luoma A, et al. MHC-II neoantigens shape tumour immunity and response to immunotherapy. Nature. 2019;574:696-701 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:300; 图 2f
Rosenbaum M, Gewies A, Pechloff K, Heuser C, Engleitner T, Gehring T, et al. Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells. Nat Commun. 2019;10:2352 pubmed 出版商
  • 流式细胞仪; 小鼠
Di Pilato M, Kim E, Cadilha B, Prüßmann J, Nasrallah M, Seruggia D, et al. Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. Nature. 2019;570:112-116 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Kotov J, Kotov D, Linehan J, Bardwell V, Gearhart M, Jenkins M. BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors. J Exp Med. 2019;216:1450-1464 pubmed 出版商
. Withdrawn: Parecoxib inhibits inflammatory responses in a mouse model of sepsis. FEBS Open Bio. 2022;12:332 pubmed 出版商
Harb H, Benamar M, Lai P, Contini P, Griffith J, Crestani E, et al. Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Immunity. 2021;54:1186-1199.e7 pubmed 出版商
Kim J, Lee E, Koo S, Kim C, Kim I. Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats. Biomed Res Int. 2021;2021:6633825 pubmed 出版商
Pang L, Huynh J, Alorro M, Li X, Ernst M, Chand A. STAT3 Signalling via the IL-6ST/gp130 Cytokine Receptor Promotes Epithelial Integrity and Intestinal Barrier Function during DSS-Induced Colitis. Biomedicines. 2021;9: pubmed 出版商
Amend A, Wickli N, Schäfer A, Sprenger D, Manz R, Voll R, et al. Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus. Int J Mol Sci. 2021;22: pubmed 出版商
Huang C, Li Z, Zhu J, Chen X, Hao Y, Yang R, et al. Systems pharmacology dissection of Epimedium targeting tumor microenvironment to enhance cytotoxic T lymphocyte responses in lung cancer. Aging (Albany NY). 2021;13:2912-2940 pubmed 出版商
Bianchi A, Marchetti L, Hall Z, Lemos H, Vacca M, Paish H, et al. Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis. J Immunol. 2021;206:904-916 pubmed 出版商
Permanyer M, Bosnjak B, Glage S, Friedrichsen M, Floess S, Huehn J, et al. Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool. Cell Mol Immunol. 2021;18:398-414 pubmed 出版商
Ebelt N, Zuniga E, Marzagalli M, Zamloot V, Blazar B, Salgia R, et al. Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy. Biomedicines. 2020;8: pubmed 出版商
Torretta S, Scagliola A, Ricci L, Mainini F, Di Marco S, Cuccovillo I, et al. D-mannose suppresses macrophage IL-1β production. Nat Commun. 2020;11:6343 pubmed 出版商
Luo Y, Wang B, Liu J, Ma F, Luo D, Zheng Z, et al. Ginsenoside RG1 enhances the paracrine effects of bone marrow-derived mesenchymal stem cells on radiation induced intestinal injury. Aging (Albany NY). 2020;13:1132-1152 pubmed 出版商
Kløve S, Genger C, Weschka D, Mousavi S, Bereswill S, Heimesaat M. Toll-Like Receptor-4 Is Involved in Mediating Intestinal and Extra-Intestinal Inflammation in Campylobacter coli-Infected Secondary Abiotic IL-10-/- Mice. Microorganisms. 2020;8: pubmed 出版商
Baraibar I, Roman M, Rodriguez Remirez M, Lopez I, Vilalta A, Guruceaga E, et al. Id1 and PD-1 Combined Blockade Impairs Tumor Growth and Survival of KRAS-mutant Lung Cancer by Stimulating PD-L1 Expression and Tumor Infiltrating CD8+ T Cells. Cancers (Basel). 2020;12: pubmed 出版商
Nguyen H, Ticer T, Bastian D, Kuril S, Li H, Du H, et al. Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease. Cell Rep. 2020;33:108316 pubmed 出版商
Ko H, Hong S, Verma R, Jung J, Lee M, Kim N, et al. Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells. Front Immunol. 2020;11:1897 pubmed 出版商
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Heimesaat M, Weschka D, Kløve S, Genger C, Biesemeier N, Mousavi S, et al. Microbiota composition and inflammatory immune responses upon peroral application of the commercial competitive exclusion product Aviguard® to microbiota-depleted wildtype mice. Eur J Microbiol Immunol (Bp). 2020;10:139-146 pubmed 出版商
Clark P, Sriramaneni R, Jin W, Jagodinsky J, Bates A, Jaquish A, et al. In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases. J Immunother Cancer. 2020;8: pubmed 出版商
Harbour S, DiToro D, Witte S, Zindl C, Gao M, Schoeb T, et al. TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity. Sci Immunol. 2020;5: pubmed 出版商
Heimesaat M, Genger C, Biesemeier N, Klove S, Weschka D, Mousavi S, et al. Inflammatory Immune Responses and Gut Microbiota Changes Following Campylobacter coli Infection of IL-10-/- Mice with Chronic Colitis. Pathogens. 2020;9: pubmed 出版商
Wang A, Yang M, Liang R, Zhu F, Zhu F, Liu X, et al. Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function. Front Immunol. 2020;11:1087 pubmed 出版商
Genger C, Kløve S, Mousavi S, Bereswill S, Heimesaat M. The conundrum of colonization resistance against Campylobacter reloaded: The gut microbota composition in conventional mice does not prevent from Campylobacter coli infection. Eur J Microbiol Immunol (Bp). 2020;10:80-90 pubmed 出版商
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Shi Y, Liu Z, Cui X, Zhao Q, Liu T. Intestinal vitamin D receptor knockout protects from oxazolone-induced colitis. Cell Death Dis. 2020;11:461 pubmed 出版商
Friesen L, Gu B, Kim C. A ligand-independent fast function of RARα promotes exit from metabolic quiescence upon T cell activation and controls T cell differentiation. Mucosal Immunol. 2020;: pubmed 出版商
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Kløve S, Genger C, Mousavi S, Weschka D, Bereswill S, Heimesaat M. Toll-Like Receptor-4 Dependent Intestinal and Systemic Sequelae Following Peroral Campylobacter coli Infection of IL10 Deficient Mice Harboring a Human Gut Microbiota. Pathogens. 2020;9: pubmed 出版商
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Kang L, Oh E, Cho C, Kwon H, Lee C, Jeon J, et al. 3'-Sialyllactose prebiotics prevents skin inflammation via regulatory T cell differentiation in atopic dermatitis mouse models. Sci Rep. 2020;10:5603 pubmed 出版商
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Anderson J, Kol A, Bizikova P, Stapelton B, Ford K, Villarreal A, et al. Immunopathogenesis of canine chronic ulcerative stomatitis. PLoS ONE. 2020;15:e0227386 pubmed 出版商
Xiong Y, Wang L, Di Giorgio E, Akimova T, Beier U, Han R, et al. Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity. J Clin Invest. 2020;130:1830-1842 pubmed 出版商
Wu R, Liu C, Deng X, Chen L, Hao S, Ma L. Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells. J Cell Mol Med. 2020;24:1684-1699 pubmed 出版商
Bishehsari F, Engen P, VOIGT R, Swanson G, Shaikh M, Wilber S, et al. Abnormal Eating Patterns Cause Circadian Disruption and Promote Alcohol-Associated Colon Carcinogenesis. Cell Mol Gastroenterol Hepatol. 2020;9:219-237 pubmed 出版商
Kuehlwein J, Borsche M, Korir P, Risch F, Mueller A, Hübner M, et al. Protection of Batf3-deficient mice from experimental cerebral malaria correlates with impaired cytotoxic T-cell responses and immune regulation. Immunology. 2020;159:193-204 pubmed 出版商
McCloskey C, Cook D, Kelly B, Azzi F, Allen C, Forsyth A, et al. Metformin Abrogates Age-Associated Ovarian Fibrosis. Clin Cancer Res. 2020;26:632-642 pubmed 出版商
Saldinger L, Nelson S, Bellone R, Lassaline M, Mack M, Walker N, et al. Horses with equine recurrent uveitis have an activated CD4+ T-cell phenotype that can be modulated by mesenchymal stem cells in vitro. Vet Ophthalmol. 2020;23:160-170 pubmed 出版商
Brichacek A, Benkovic S, Chakraborty S, Nwafor D, Wang W, Jun S, et al. Systemic inhibition of tissue-nonspecific alkaline phosphatase alters the brain-immune axis in experimental sepsis. Sci Rep. 2019;9:18788 pubmed 出版商
Carper M, Troutman S, Wagner B, Byrd K, Selitsky S, Parag Sharma K, et al. An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma. Cell Rep. 2019;29:1660-1674.e7 pubmed 出版商
Kusano T, Ehirchiou D, Matsumura T, Chobaz V, Nasi S, Castelblanco M, et al. Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth. Nat Commun. 2019;10:4904 pubmed 出版商
Wang X, Balaji S, Steen E, Li H, Rae M, Blum A, et al. T Lymphocytes Attenuate Dermal Scarring by Regulating Inflammation, Neovascularization, and Extracellular Matrix Remodeling. Adv Wound Care (New Rochelle). 2019;8:527-537 pubmed 出版商
Zammit N, Walters S, Seeberger K, O Connell P, Korbutt G, Grey S. A20 as an immune tolerance factor can determine islet transplant outcomes. JCI Insight. 2019;4: pubmed 出版商
Abughanam G, Elkashty O, Liu Y, Bakkar M, Tran S. Mesenchymal Stem Cells Extract (MSCsE)-Based Therapy Alleviates Xerostomia and Keratoconjunctivitis Sicca in Sjogren's Syndrome-Like Disease. Int J Mol Sci. 2019;20: pubmed 出版商
Wang P, Qi X, Xu G, Liu J, Guo J, Li X, et al. CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells. Aging (Albany NY). 2019;11:7402-7415 pubmed 出版商
Mousavi S, Lobo de Sá F, Schulzke J, Bücker R, Bereswill S, Heimesaat M. Vitamin D in Acute Campylobacteriosis-Results From an Intervention Study Applying a Clinical Campylobacter jejuni Induced Enterocolitis Model. Front Immunol. 2019;10:2094 pubmed 出版商
Do D, Mu J, Ke X, Sachdeva K, Qin Z, Wan M, et al. miR-511-3p protects against cockroach allergen-induced lung inflammation by antagonizing CCL2. JCI Insight. 2019;4: pubmed 出版商
Chen M, Reed R, Lane A. Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense. Cell Stem Cell. 2019;25:501-513.e5 pubmed 出版商
Wolf Y, Bartok O, Patkar S, Eli G, Cohen S, Litchfield K, et al. UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma. Cell. 2019;179:219-235.e21 pubmed 出版商
Yamada T, Hino S, Iijima H, Genda T, Aoki R, Nagata R, et al. Mucin O-glycans facilitate symbiosynthesis to maintain gut immune homeostasis. EBioMedicine. 2019;48:513-525 pubmed 出版商
Xu J, Pei S, Wang Y, Liu J, Qian Y, Huang M, et al. Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells. Front Immunol. 2019;10:1980 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
FOXP3 Monoclonal Antibody (FJK-16s), eBioscience
目录# :
14-5773-37
规格 :
2毫克
价格 :
美国1234
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
牛, 狗, 猫, 小鼠, 猪, 大鼠
应用 :
Immunohistochemistry (Frozen): 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 5 µg/mL
物种 :
牛, 狗, 猫, 小鼠, 猪, 大鼠
克隆 :
FJK-16s
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome. Transcript variants of FOXP3 encoding different isoforms have been identified. In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Frozen): 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 5 µg/mL
别名 :
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID
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