产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD49b (Integrin alpha 2) Monoclonal Antibody (DX5), eBioscience
目录 :
14-5971-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
DX5
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 111
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 s3
Flamini S, Sergeev P, Viana de Barros Z, Mello T, Biagioli M, Paglialunga M, et al. Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment. Cell Death Dis. 2021;12:421 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 s3d, 7b
Asrat S, Kaur N, Liu X, Ben L, Kajimura D, Murphy A, et al. Chronic allergen exposure drives accumulation of long-lived IgE plasma cells in the bone marrow, giving rise to serological memory. Sci Immunol. 2020;5: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:500; 图 5a
Davies A, Kim H, González Cano R, Choi J, Back S, Roh S, et al. Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury. Cell. 2019;176:716-728.e18 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200
Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, et al. LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. Nature. 2018;562:605-609 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1c
Abel A, Tiwari A, Gerbec Z, Siebert J, Yang C, Schloemer N, et al. IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. Front Immunol. 2018;9:1168 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s10d
Billerbeck E, Wolfisberg R, Fahnøe U, Xiao J, Quirk C, Luna J, et al. Mouse models of acute and chronic hepacivirus infection. Science. 2017;357:204-208 pubmed 出版商
  • 流式细胞仪; 小鼠
Schuetz C, Lee K, Scott R, Kojima L, Washburn L, Liu L, et al. Regulatory B Cell-Dependent Islet Transplant Tolerance Is Also Natural Killer Cell Dependent. Am J Transplant. 2017;17:1656-1662 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Bieber K, Witte M, Sun S, Hundt J, Kalies K, Dräger S, et al. T cells mediate autoantibody-induced cutaneous inflammation and blistering in epidermolysis bullosa acquisita. Sci Rep. 2016;6:38357 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2d
Sektioglu I, Carretero R, Bulbuc N, Bald T, Tüting T, Rudensky A, et al. Basophils Promote Tumor Rejection via Chemotaxis and Infiltration of CD8+ T Cells. Cancer Res. 2017;77:291-302 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed 出版商
  • 流式细胞仪; 小鼠
Yoon J, Leyva Castillo J, Wang G, Galand C, Oyoshi M, Kumar L, et al. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016;213:2147-66 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100
Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Lin C, Bradstreet T, Schwarzkopf E, Jarjour N, Chou C, Archambault A, et al. IL-1-induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation. J Exp Med. 2016;213:251-71 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1e
Wilson K, Goding S, Neely H, Harris K, Antony P. Depletion of B220+NK1.1+ cells enhances the rejection of established melanoma by tumor-specific CD4+ T cells. Oncoimmunology. 2015;4:e1019196 pubmed
  • 流式细胞仪; 小鼠; 图 2
Guo L, Huang Y, Chen X, Hu Li J, Urban J, Paul W. Innate immunological function of TH2 cells in vivo. Nat Immunol. 2015;16:1051-9 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
Littwitz Salomon E, Akhmetzyanova I, Vallet C, Francois S, Dittmer U, Gibbert K. Activated regulatory T cells suppress effector NK cell responses by an IL-2-mediated mechanism during an acute retroviral infection. Retrovirology. 2015;12:66 pubmed 出版商
  • 流式细胞仪; 小鼠
Vogel A, Brown D. Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells. Front Immunol. 2015;6:327 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Wensveen F, Jelenčić V, Valentić S, Å estan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Krishnamoorthy N, Burkett P, Dalli J, Abdulnour R, Colas R, Ramon S, et al. Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation. J Immunol. 2015;194:863-7 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Wu X, Satpathy A, Kc W, Liu P, Murphy T, Murphy K. Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo. PLoS ONE. 2013;8:e64800 pubmed 出版商
  • 流式细胞仪; 小鼠
Loebbermann J, Schnoeller C, Thornton H, Durant L, Sweeney N, Schuijs M, et al. IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice. PLoS ONE. 2012;7:e32371 pubmed 出版商
  • 流式细胞仪; 小鼠
Liang H, Reinhardt R, Bando J, Sullivan B, Ho I, Locksley R. Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity. Nat Immunol. 2011;13:58-66 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Yan S, Wang L, Liu N, Wang Y, Chu Y. Critical role of interleukin-17/interleukin-17 receptor axis in mediating Con A-induced hepatitis. Immunol Cell Biol. 2012;90:421-8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Zou Y, Chen T, Han M, Wang H, Yan W, Song G, et al. Increased killing of liver NK cells by Fas/Fas ligand and NKG2D/NKG2D ligand contributes to hepatocyte necrosis in virus-induced liver failure. J Immunol. 2010;184:466-75 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Fahl S, Crittenden R, Allman D, Bender T. c-Myb is required for pro-B cell differentiation. J Immunol. 2009;183:5582-92 pubmed 出版商
  • 流式细胞仪; 小鼠
Huntington N, Legrand N, Alves N, Jaron B, Weijer K, Plet A, et al. IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J Exp Med. 2009;206:25-34 pubmed 出版商
  • 流式细胞仪; 小鼠
Zhang J, Kawashima N, Suda H, Nakano Y, Takano Y, Azuma M. The existence of CD11c+ sentinel and F4/80+ interstitial dendritic cells in dental pulp and their dynamics and functional properties. Int Immunol. 2006;18:1375-84 pubmed
  • 流式细胞仪; 小鼠
Rubinstein M, Kovar M, Purton J, Cho J, Boyman O, Surh C, et al. Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}. Proc Natl Acad Sci U S A. 2006;103:9166-71 pubmed
  • 流式细胞仪; 小鼠
Fallon P, Ballantyne S, Mangan N, Barlow J, Dasvarma A, Hewett D, et al. Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med. 2006;203:1105-16 pubmed
Li M, McGhee E, Shinno L, Lee K, Lin Y. Exposure to Microbial Metabolite Butyrate Prolongs the Survival Time and Changes the Growth Pattern of Human Papillomavirus 16 E6/E7-Immortalized Keratinocytes in Vivo. Am J Pathol. 2021;191:1822-1836 pubmed 出版商
Chen S, Chen X, Qiu J, Chen P, Han X, Wu Y, et al. Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment. Oncol Rep. 2021;45:278-290 pubmed 出版商
Kong M, Hashimoto Tane A, Kawashima Y, Sakuma M, Yokosuka T, Kometani K, et al. Inhibition of T cell activation and function by the adaptor protein CIN85. Sci Signal. 2019;12: pubmed 出版商
Ford J, Hughson A, Lim K, Bardina S, Lu W, Charo I, et al. CCL7 Is a Negative Regulator of Cutaneous Inflammation Following Leishmania major Infection. Front Immunol. 2018;9:3063 pubmed 出版商
Yagisawa T, Tanaka T, Miyairi S, Tanabe K, Dvorina N, Yokoyama W, et al. In the absence of natural killer cell activation donor-specific antibody mediates chronic, but not acute, kidney allograft rejection. Kidney Int. 2019;95:350-362 pubmed 出版商
Hansell C, Fraser A, Hayes A, Pingen M, Burt C, Lee K, et al. The Atypical Chemokine Receptor Ackr2 Constrains NK Cell Migratory Activity and Promotes Metastasis. J Immunol. 2018;201:2510-2519 pubmed 出版商
Meroni E, Stakenborg N, Gomez Pinilla P, De Hertogh G, Goverse G, Matteoli G, et al. Functional characterization of oxazolone-induced colitis and survival improvement by vagus nerve stimulation. PLoS ONE. 2018;13:e0197487 pubmed 出版商
Bloodworth M, Rusznak M, Pfister C, Zhang J, Bastarache L, Calvillo S, et al. Glucagon-like peptide-1 receptor signaling attenuates RSV-induced type 2 responses and immunopathology. J Allergy Clin Immunol. 2018;: pubmed 出版商
Dimayuga P, Zhao X, Yano J, Lio W, Zhou J, Mihailovic P, et al. Identification of apoB-100 Peptide-Specific CD8+ T Cells in Atherosclerosis. J Am Heart Assoc. 2017;6: pubmed 出版商
Miletić A, Lenartic M, Popovic B, Brizic I, Trsan T, Miklic K, et al. NCR1-deficiency diminishes the generation of protective murine cytomegalovirus antibodies by limiting follicular helper T-cell maturation. Eur J Immunol. 2017;47:1443-1456 pubmed 出版商
Shan Q, Zeng Z, Xing S, Li F, Hartwig S, Gullicksrud J, et al. The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage. Nat Immunol. 2017;18:931-939 pubmed 出版商
Lehmann C, Baranska A, Heidkamp G, Heger L, Neubert K, Lühr J, et al. DC subset-specific induction of T cell responses upon antigen uptake via Fc? receptors in vivo. J Exp Med. 2017;214:1509-1528 pubmed 出版商
Hidaka T, Ogawa E, Kobayashi E, Suzuki T, Funayama R, Nagashima T, et al. The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. Nat Immunol. 2017;18:64-73 pubmed 出版商
Müller A, Florek M, Kohrt H, Küpper N, Filatenkov A, Linderman J, et al. Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning. J Immunol. 2016;197:4151-4162 pubmed
Henry E, Sy C, Inclan Rico J, Espinosa V, Ghanny S, Dwyer D, et al. Carbonic anhydrase enzymes regulate mast cell-mediated inflammation. J Exp Med. 2016;213:1663-73 pubmed 出版商
Lenac Rovis T, Kucan Brlic P, Kaynan N, Juranic Lisnic V, Brizic I, Jordan S, et al. Inflammatory monocytes and NK cells play a crucial role in DNAM-1-dependent control of cytomegalovirus infection. J Exp Med. 2016;213:1835-50 pubmed 出版商
Wilhelm C, Harrison O, Schmitt V, Pelletier M, Spencer S, Urban J, et al. Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection. J Exp Med. 2016;213:1409-18 pubmed 出版商
Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed 出版商
Chen J, Schlitzer A, Chakarov S, Ginhoux F, Poidinger M. Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development. Nat Commun. 2016;7:11988 pubmed 出版商
Li J, Dong X, Zhao L, Wang X, Wang Y, Yang X, et al. Natural killer cells regulate Th1/Treg and Th17/Treg balance in chlamydial lung infection. J Cell Mol Med. 2016;20:1339-51 pubmed 出版商
Doorduijn E, Sluijter M, Querido B, Oliveira C, Achour A, Ossendorp F, et al. TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors. J Clin Invest. 2016;126:784-94 pubmed 出版商
Oh J, Lee M, Kim Y, Lee H. OASL1 deficiency promotes antiviral protection against genital herpes simplex virus type 2 infection by enhancing type I interferon production. Sci Rep. 2016;6:19089 pubmed 出版商
Fernández Santoscoy M, Wenzel U, Yrlid U, Cardell S, Backhed F, Wick M. The Gut Microbiota Reduces Colonization of the Mesenteric Lymph Nodes and IL-12-Independent IFN-γ Production During Salmonella Infection. Front Cell Infect Microbiol. 2015;5:93 pubmed 出版商
Jabara H, Boyden S, Chou J, Ramesh N, Massaad M, Benson H, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016;48:74-8 pubmed 出版商
Krneta T, Gillgrass A, Chew M, Ashkar A. The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cell Mol Immunol. 2016;13:628-39 pubmed 出版商
Mohapatra A, Van Dyken S, Schneider C, Nussbaum J, Liang H, Locksley R. Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis. Mucosal Immunol. 2016;9:275-86 pubmed 出版商
Freeman B, Raué H, Hill A, Slifka M. Cytokine-Mediated Activation of NK Cells during Viral Infection. J Virol. 2015;89:7922-31 pubmed 出版商
Burks J, Reed R, Desai S. Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective. Oncotarget. 2015;6:7221-31 pubmed
Verma S, Loewendorf A, Wang Q, McDonald B, Redwood A, Benedict C. Inhibition of the TRAIL death receptor by CMV reveals its importance in NK cell-mediated antiviral defense. PLoS Pathog. 2014;10:e1004268 pubmed 出版商
Cao Q, Wang Y, Wang X, Lu J, Lee V, Ye Q, et al. Renal F4/80+ CD11c+ mononuclear phagocytes display phenotypic and functional characteristics of macrophages in health and in adriamycin nephropathy. J Am Soc Nephrol. 2015;26:349-63 pubmed 出版商
Ford L, Cerovic V, Milling S, Graham G, Hansell C, Nibbs R. Characterization of conventional and atypical receptors for the chemokine CCL2 on mouse leukocytes. J Immunol. 2014;193:400-11 pubmed 出版商
Ibrahim M, Barnes J, Osorio E, Anstead G, Jimenez F, Osterholzer J, et al. Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection. Infect Immun. 2014;82:3098-112 pubmed 出版商
Nandagopal N, Ali A, Komal A, Lee S. The Critical Role of IL-15-PI3K-mTOR Pathway in Natural Killer Cell Effector Functions. Front Immunol. 2014;5:187 pubmed 出版商
Bhadra R, Moretto M, Castillo J, Petrovas C, Ferrando Martinez S, Shokal U, et al. Intrinsic TGF-? signaling promotes age-dependent CD8+ T cell polyfunctionality attrition. J Clin Invest. 2014;124:2441-55 pubmed 出版商
Sojka D, Plougastel Douglas B, Yang L, Pak Wittel M, Artyomov M, Ivanova Y, et al. Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells. elife. 2014;3:e01659 pubmed 出版商
Tung H, Plunkett B, Huang S, Zhou Y. Murine mast cells secrete and respond to interleukin-33. J Interferon Cytokine Res. 2014;34:141-7 pubmed 出版商
Kaanta A, Virtanen C, Selfors L, Brugge J, Neel B. Evidence for a multipotent mammary progenitor with pregnancy-specific activity. Breast Cancer Res. 2013;15:R65 pubmed
Bulliard Y, Jolicoeur R, Windman M, Rue S, Ettenberg S, Knee D, et al. Activating Fc ? receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies. J Exp Med. 2013;210:1685-93 pubmed 出版商
Cravens P, Kieseier B, Hussain R, Herndon E, Arellano B, Ben L, et al. The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis. J Neuroinflammation. 2013;10:67 pubmed 出版商
Taketomi Y, Ueno N, Kojima T, Sato H, Murase R, Yamamoto K, et al. Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis. Nat Immunol. 2013;14:554-63 pubmed 出版商
Arpke R, Darabi R, Mader T, Zhang Y, Toyama A, Lonetree C, et al. A new immuno-, dystrophin-deficient model, the NSG-mdx(4Cv) mouse, provides evidence for functional improvement following allogeneic satellite cell transplantation. Stem Cells. 2013;31:1611-20 pubmed 出版商
Leifler K, Svensson S, Abrahamsson A, Bendrik C, Robertson J, Gauldie J, et al. Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer. J Immunol. 2013;190:4420-30 pubmed 出版商
Zhong M, Veillette A. Critical role of SAP in progression and reactivation but not maintenance of T cell-dependent humoral immunity. Mol Cell Biol. 2013;33:1223-32 pubmed 出版商
Cheng L, Hartmann K, Roers A, Krummel M, Locksley R. Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E. Immunity. 2013;38:166-75 pubmed 出版商
van Helden M, Zaiss D, Sijts A. CCR2 defines a distinct population of NK cells and mediates their migration during influenza virus infection in mice. PLoS ONE. 2012;7:e52027 pubmed 出版商
Mizutani T, Neugebauer N, Putz E, Moritz N, Simma O, Zebedin Brandl E, et al. Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance. Oncoimmunology. 2012;1:1027-1037 pubmed
Goulding J, Bogue R, Tahiliani V, Croft M, Salek Ardakani S. CD8 T cells are essential for recovery from a respiratory vaccinia virus infection. J Immunol. 2012;189:2432-40 pubmed 出版商
van Helden M, de Graaf N, Boog C, Topham D, Zaiss D, Sijts A. The bone marrow functions as the central site of proliferation for long-lived NK cells. J Immunol. 2012;189:2333-7 pubmed 出版商
Valdez P, Vithayathil P, Janelsins B, Shaffer A, Williamson P, Datta S. Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells. Immunity. 2012;36:668-79 pubmed 出版商
Castro Seoane R, Hummerich H, Sweeting T, Tattum M, Linehan J, Fernández de Marco M, et al. Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection. PLoS Pathog. 2012;8:e1002538 pubmed 出版商
Saran N, Pommerencke J, Witzlau K, Regelin M, Krueger A. Extra-thymic physiological T lineage progenitor activity is exclusively confined to cells expressing either CD127, CD90, or high levels of CD117. PLoS ONE. 2012;7:e30864 pubmed 出版商
Nouri Shirazi M, Guinet E. Exposure to nicotine adversely affects the dendritic cell system and compromises host response to vaccination. J Immunol. 2012;188:2359-70 pubmed 出版商
Kim H, Lee J, Kim J, Cha H, Kim A, Lee S, et al. Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation. Proc Natl Acad Sci U S A. 2012;109:E13-22 pubmed 出版商
Yamashita J, Iwamura C, Mitsumori K, Hosokawa H, Sasaki T, Takahashi M, et al. Murine Schnurri-2 controls natural killer cell function and lymphoma development. Leuk Lymphoma. 2012;53:479-86 pubmed 出版商
Heiber J, Barber G. Vesicular stomatitis virus expressing tumor suppressor p53 is a highly attenuated, potent oncolytic agent. J Virol. 2011;85:10440-50 pubmed 出版商
Sprague L, Muccioli M, Pate M, Meles E, McGinty J, Nandigam H, et al. The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells. BMC Immunol. 2011;12:35 pubmed 出版商
Mkhikian H, Grigorian A, Li C, Chen H, Newton B, Zhou R, et al. Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis. Nat Commun. 2011;2:334 pubmed 出版商
Werner J, Busl E, Farkas S, Schlitt H, Geissler E, Hornung M. DX5+NKT cells display phenotypical and functional differences between spleen and liver as well as NK1.1-Balb/c and NK1.1+ C57Bl/6 mice. BMC Immunol. 2011;12:26 pubmed 出版商
Nakagawa Y, Takamatsu H, Okuno T, Kang S, Nojima S, Kimura T, et al. Identification of semaphorin 4B as a negative regulator of basophil-mediated immune responses. J Immunol. 2011;186:2881-8 pubmed 出版商
Bou Ghanem E, Nelson C, D Orazio S. T cell-intrinsic factors contribute to the differential ability of CD8+ T cells to rapidly secrete IFN-? in the absence of antigen. J Immunol. 2011;186:1703-12 pubmed 出版商
Cheng L, Wang Z, Locksley R. Murine B cells regulate serum IgE levels in a CD23-dependent manner. J Immunol. 2010;185:5040-7 pubmed 出版商
Chuikov S, Levi B, Smith M, Morrison S. Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress. Nat Cell Biol. 2010;12:999-1006 pubmed 出版商
Elliott J, Wahle J, Yokoyama W. MHC class I-deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I-sufficient environment. J Exp Med. 2010;207:2073-9 pubmed 出版商
Freire T, Zhang X, Deriaud E, Ganneau C, Vichier Guerre S, Azria E, et al. Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant. Blood. 2010;116:3526-36 pubmed 出版商
Zhu Y, Ju S, Chen E, Dai S, Li C, MOREL P, et al. T-bet and eomesodermin are required for T cell-mediated antitumor immune responses. J Immunol. 2010;185:3174-83 pubmed 出版商
Cheung T, Oborne L, Steinberg M, Macauley M, Fukuyama S, Sanjo H, et al. T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment. J Immunol. 2009;183:7286-96 pubmed 出版商
Himoudi N, Yan M, Bouma G, Morgenstern D, Wallace R, Seddon B, et al. Migratory and antigen presentation functions of IFN-producing killer dendritic cells. Cancer Res. 2009;69:6598-606 pubmed 出版商
Steel C, Hahto S, Ciavarra R. Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system. Virology. 2009;387:117-26 pubmed 出版商
Orr S, Quigley L, McVicar D. In vivo expression of signaling proteins in reconstituted NK cells. J Immunol Methods. 2009;340:158-63 pubmed 出版商
Albu D, Feng D, Bhattacharya D, Jenkins N, Copeland N, Liu P, et al. BCL11B is required for positive selection and survival of double-positive thymocytes. J Exp Med. 2007;204:3003-15 pubmed
Sun C, Hall J, Blank R, Bouladoux N, Oukka M, Mora J, et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med. 2007;204:1775-85 pubmed
Lappas C, Day Y, Marshall M, Engelhard V, Linden J. Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation. J Exp Med. 2006;203:2639-48 pubmed
Garbe A, Krueger A, Gounari F, Zuniga Pflucker J, von Boehmer H. Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate. J Exp Med. 2006;203:1579-90 pubmed
Borchers M, Harris N, Wesselkamper S, Zhang S, Chen Y, Young L, et al. The NKG2D-activating receptor mediates pulmonary clearance of Pseudomonas aeruginosa. Infect Immun. 2006;74:2578-86 pubmed
Tacke F, Ginhoux F, Jakubzick C, Van Rooijen N, Merad M, Randolph G. Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery. J Exp Med. 2006;203:583-97 pubmed
Setoguchi R, Hori S, Takahashi T, Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med. 2005;201:723-35 pubmed
Esplugues E, Sancho D, Vega Ramos J, Martinez C, Syrbe U, Hamann A, et al. Enhanced antitumor immunity in mice deficient in CD69. J Exp Med. 2003;197:1093-106 pubmed
Arase H, Saito T, Phillips J, Lanier L. Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). J Immunol. 2001;167:1141-4 pubmed
Rodewald H, Waskow C, Haller C. Essential requirement for c-kit and common gamma chain in thymocyte development cannot be overruled by enforced expression of Bcl-2. J Exp Med. 2001;193:1431-7 pubmed
Hussell T, Openshaw P. Intracellular IFN-gamma expression in natural killer cells precedes lung CD8+ T cell recruitment during respiratory syncytial virus infection. J Gen Virol. 1998;79 ( Pt 11):2593-601 pubmed
Vos Q, Ortaldo J, Conan Cibotti M, Vos M, Young H, Anderson S, et al. Phenotypic and functional characterization of a panel of cytotoxic murine NK cell clones that are heterogeneous in their enhancement of Ig secretion in vitro. Int Immunol. 1998;10:1093-101 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD49b (Integrin alpha 2) Monoclonal Antibody (DX5), eBioscience
目录# :
14-5971-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test
物种 :
小鼠
克隆 :
DX5
抗体亚型 :
IgM, kappa
储存 :
4° C
描述 :
CD49b (Integrin alpha 2, Integrin alpha 2 chain, VLA-2 alpha chain, HM alpha 2) is a member of the integrin family. It is a glycoprotein with molecular weight of 150 kD, and it complexes with CD29 (Integrin beta 1) to form the heterodimeric integrin VLA-2 (integrin alpha 2 beta 1, or GPIa/IIa) complex. VLA-2 is an extracellular receptor for laminin, collagen, and fibronectin, and interaction with its ligands results in the activation of intracellular signaling pathways. It has reported roles in VEGF-induced angiogenesis in vivo, as well as adhesion and lymphocyte activation. CD49b is expressed by NK cells, NK-T cells, monocytes, platelets, and epithelial cells. It is also expressed on adaptive immune cells such as T and B cells, specifically on a subset of CD4+ T cells in the spleen, on intraepithelial and lamina propria lymphocytes in the intestine, as well as on a population of peripheral CD4+ type 1 T regulatory (Tr1) cells that co-express LAG-3.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test
别名 :
alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国