PARP1 Monoclonal Antibody (HC2R8), eBioscience | 赛默飞世尔 14-6667-82 产品信息

产品简要

公司名称 :

赛默飞世尔

其他品牌 :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

产品类型 :

抗体

产品名称 :

PARP1 Monoclonal Antibody (HC2R8), eBioscience

14-6667-82

规格 :

100微克

价格 :

美国309.00

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

HC2R8

反应物种 :

人类

应用 :

免疫印迹, 免疫细胞化学

更多信息或购买 :

赛默飞世尔产品网页

文章摘录数: 6

参考文献
Kerr E, Holohan C, McLaughlin K, Majkut J, Dolan S, Redmond K, et al. Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis. Cell Death Differ. 2012;19:1317-27 pubmed 出版商
Patel T, Gores G, Kaufmann S. The role of proteases during apoptosis. FASEB J. 1996;10:587-97 pubmed
Tewari M, Quan L, O Rourke K, Desnoyers S, Zeng Z, Beidler D, et al. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 1995;81:801-9 pubmed
Zahradka P, Ebisuzaki K. Poly(ADP-ribose) polymerase is a zinc metalloenzyme. Eur J Biochem. 1984;142:503-9 pubmed
Lamarre D, Talbot B, de Murcia G, Laplante C, Leduc Y, Mazen A, et al. Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study. Biochim Biophys Acta. 1988;950:147-60 pubmed
Lamarre D, Talbot B, Leduc Y, Muller S, Poirier G. Production and characterization of monoclonal antibodies specific for the functional domains of poly(ADP-ribose) polymerase. Biochem Cell Biol. 1986;64:368-76 pubmed

产品信息

产品类型 :

抗体

产品名称 :

PARP1 Monoclonal Antibody (HC2R8), eBioscience

目录# :

14-6667-82

规格 :

100微克

价格 :

美国309.00

克隆性 :

单克隆

纯度 :

亲和色谱

宿主 :

小鼠

反应物种 :

人类

应用 :

Immunocytochemistry: 5 µg/mL, Western Blot: 0.1 µg/mL

物种 :

人类

克隆 :

HC2R8

抗体亚型 :

IgG2b, kappa

储存 :

4° C

描述 :

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.

格式 :

液体

应用w/稀释 :

Immunocytochemistry: 5 µg/mL, Western Blot: 0.1 µg/mL

别名 :

5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; Adprt; ADPRT 1; Adprt1; AI893648; ARTD1; C80510; DNA ADP-ribosyltransferase PARP1; I79_014850; msPARP; NAD(+) ADP-ribosyltransferase 1; NAD(+) pADPRT-1; pADPRT-1; PARP; PARP1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); poly [ADP-ribose] polymerase 1; poly ADP-ribose polymerase; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein poly-ADP-ribosyltransferase PARP1; sPARP-1; synthetase fragment (AA 67); Unknown (protein for IMAGE:8023736); unnamed protein product

更多信息或购买 :

赛默飞世尔产品网页

公司信息

赛默飞世尔

上海浦东新金桥路27号7号楼

analyze.cn@thermofisher.com

http://www.thermo.com.cn

1084193588

公司总部: 美国