产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-4 Monoclonal Antibody (MP4-25D2), eBioscience™
目录 :
14-7048-81
规格 :
50µg
价格 :
美国85.75
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
MP4-25D2
反应物种 :
人类
应用 :
流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 37
出版应用/物种/样本/稀释 | 参考文献 |
---|---|
| |
| |
| |
| Yamada H, Nakashima Y, Okazaki K, Mawatari T, Fukushi J, Kaibara N, et al. Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis. Ann Rheum Dis. 2008;67:1299-304 pubmed
|
| De Fanis U, Mori F, Kurnat R, Lee W, Bova M, Adkinson N, et al. GATA3 up-regulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cells. Blood. 2007;109:4343-50 pubmed
|
Yan R, Zhong W, Zhu Y, Zhang X. Trichosanthin-stimulated dendritic cells induce a type 2 helper T lymphocyte response through the OX40 ligand. J Investig Allergol Clin Immunol. 2012;22:491-500 pubmed
| |
Suzukawa M, Iikura M, Koketsu R, Nagase H, Tamura C, Komiya A, et al. An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor. J Immunol. 2008;181:5981-9 pubmed
| |
Hartigan O Connor D, Abel K, McCune J. Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression. J Exp Med. 2007;204:2679-92 pubmed
| |
Soler D, Chapman T, Poisson L, Wang L, Cote Sierra J, Ryan M, et al. CCR8 expression identifies CD4 memory T cells enriched for FOXP3+ regulatory and Th2 effector lymphocytes. J Immunol. 2006;177:6940-51 pubmed
| |
Ramanathan L, Ingram R, Sullivan L, Greenberg R, Reim R, Trotta P, et al. Immunochemical mapping of domains in human interleukin 4 recognized by neutralizing monoclonal antibodies. Biochemistry. 1993;32:3549-56 pubmed
| |
Abrams J, Roncarolo M, Yssel H, Andersson U, Gleich G, Silver J. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev. 1992;127:5-24 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
IL-4 Monoclonal Antibody (MP4-25D2), eBioscience™
目录# :
14-7048-81
规格 :
50µg
价格 :
美国85.75
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent
物种 :
人类
克隆 :
MP4-25D2
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent
别名 :
B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; Binetrakin; BOS_7769; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; Il4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; Interleukin4; Interleukin-4; interleukin-4 precursor; Lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
更多信息或购买 :
公司信息
赛默飞世尔
微博分享
关注我们的微博
- 来邦网
- 英文来邦
产品浏览
问题和意见