产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-6 Monoclonal Antibody (MQ2-13A5), eBioscience™
目录 :
14-7069-85
规格 :
500µg
价格 :
美国249
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
MQ2-13A5
反应物种 :
人类
应用 :
酶联免疫吸附测定, 流式细胞仪, 抑制或激活实验, 其他
更多信息或购买 :
文章摘录数: 34
出版应用/物种/样本/稀释 | 参考文献 |
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| De Paoli M, Gogalic S, Sauer U, Preininger C, Pandha H, Simpson G, et al. Multiplatform Biomarker Discovery for Bladder Cancer Recurrence Diagnosis. Dis Markers. 2016;2016:4591910 pubmed
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Barrionuevo P, Cassataro J, Delpino M, Zwerdling A, Pasquevich K, García Samartino C, et al. Brucella abortus inhibits major histocompatibility complex class II expression and antigen processing through interleukin-6 secretion via Toll-like receptor 2. Infect Immun. 2008;76:250-62 pubmed
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Gaines Das R, Poole S. The international standard for interleukin-6. Evaluation in an international collaborative study. J Immunol Methods. 1993;160:147-53 pubmed
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Andersson J, Abrams J, Bjork L, Funa K, Litton M, Agren K, et al. Concomitant in vivo production of 19 different cytokines in human tonsils. Immunology. 1994;83:16-24 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
IL-6 Monoclonal Antibody (MQ2-13A5), eBioscience™
目录# :
14-7069-85
规格 :
500µg
价格 :
美国249
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
人类
应用 :
ELISA:2-8微克/毫升
物种 :
人类
克隆 :
MQ2-13A5
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
Interleukin 6 (IL-6) is a multifunctional 26 kD protein originally discovered in the medium of RNA-stimulated fibroblastoid cells. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be important as IL-1 and TNF-a in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. IL-6 acts upon a variety of cells including myeloid progenitor cells, T cells, B cells, and hepatocytes. In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. Primarily produced at sites of acute and chronic inflammation, IL-6 is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states including diabetes mellitus and systemic juvenile rheumatoid arthritis.
格式 :
液体
应用w/稀释 :
ELISA:2-8微克/毫升
别名 :
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BOS_4106; BSF2; BSF-2; CDF; ChIL-6; CTL differentiation factor; EGM_12696; HGF; H-IL-6; HSF; Hybridoma growth factor; hypothetical protein; IFNB2; IFN-beta-2; IL6; Il-6; ILg6; ILN; Interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin BSF-2; Interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 protein; M-IL-6; R-IL-6
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