产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-12/IL-23 p40 Monoclonal Antibody (C15.6), eBioscience™
目录 :
14-7125-81
规格 :
50µg
价格 :
美国96.5
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
C15.6
反应物种 :
小鼠
应用 :
酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 酶联免疫吸附测定; 小鼠; 1 ug/ml; 图 1e
Roberts A, Popov L, Mitchell G, Ching K, Licht D, Golovkine G, et al. Cas9+ conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond. elife. 2019;8: pubmed 出版商
  • 酶联免疫吸附测定; 小鼠; 图 1c
Napolitano A, van der Veen A, Bunyan M, Borg A, Frith D, Howell S, et al. Cysteine-Reactive Free ISG15 Generates IL-1β-Producing CD8α+ Dendritic Cells at the Site of Infection. J Immunol. 2018;201:604-614 pubmed 出版商
Shin K, Kataru R, Park H, Kwon B, Kim T, Hong Y, et al. TH2 cells and their cytokines regulate formation and function of lymphatic vessels. Nat Commun. 2015;6:6196 pubmed 出版商
Mosconi I, Geuking M, Zaiss M, Massacand J, Aschwanden C, Kwong Chung C, et al. Intestinal bacteria induce TSLP to promote mutualistic T-cell responses. Mucosal Immunol. 2013;6:1157-67 pubmed 出版商
Ricciardelli C, Frewin K, Tan I, Williams E, Opeskin K, Pritchard M, et al. The ADAMTS1 protease gene is required for mammary tumor growth and metastasis. Am J Pathol. 2011;179:3075-85 pubmed 出版商
Freigang S, Ampenberger F, Spohn G, Heer S, Shamshiev A, Kisielow J, et al. Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis. Eur J Immunol. 2011;41:2040-51 pubmed 出版商
Couper K, Blount D, Hafalla J, Van Rooijen N, de Souza J, Riley E. Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia. Infect Immun. 2007;75:5806-18 pubmed
Masek K, Fiore J, Leitges M, Yan S, Freedman B, Hunter C. Host cell Ca2+ and protein kinase C regulate innate recognition of Toxoplasma gondii. J Cell Sci. 2006;119:4565-73 pubmed
Wysocka M, Kubin M, Vieira L, Ozmen L, Garotta G, Scott P, et al. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur J Immunol. 1995;25:672-6 pubmed
产品信息
产品类型 :
抗体
产品名称 :
IL-12/IL-23 p40 Monoclonal Antibody (C15.6), eBioscience™
目录# :
14-7125-81
规格 :
50µg
价格 :
美国96.5
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
ELISA:0.25-1微克/毫升
物种 :
小鼠
克隆 :
C15.6
抗体亚型 :
IgG1
储存 :
4° C
描述 :
IL-12 is an interleukin produced by dendritic cells, neutrophils, macrophages and human lymphoblastoid cells as a result of antigenic stimulation. IL-12 is a heterodimeric cytokine encoded by IL-12A (p35) and IL-12B (p40). IL-23 is a heterodimeric cytokine that shares a subunit with IL-12 (IL-12B) along with an IL-23A (IL-23p19) subunit. Functionally, IL-12 increases the expression of vascular endothelial adhesion molecule-1 on the endothelium, directs leukocytes towards tumors and facilitates the ischemic-hemorrhagic necrosis of the tumor tissue. In comparison, IL-23 plays an important role in stimulating memory T-cells, and is required for the induction, expansion, maintenance and downstream effector functions of Th17 cells, which play a vital role in upregulating neutrophil chemokines and various pro-inflammatory cytokines.
格式 :
液体
应用w/稀释 :
ELISA:0.25-1微克/毫升
别名 :
BOS_5471; BOS_8400; CLMF; CLMF p40; CLMF2; Cytotoxic lymphocyte maturation factor 40 kDa subunit; il 12; IL 12/IL 23p40; il 23; IL 23 p40; Il12; IL-12 subunit p40; IL12, subunit p40; Il12b; IL-12B; Il12p40; Il-12p40; il23; IL-23; IL23 p41; IL-23 subunit alpha; IL23A; IL-23A; IL-23-A; IL23P19; IL-23p19; ILN; IMD28; IMD29; Interleukin; Interleukin 12; interleukin 12 40kDa subunit; interleukin 12, p40; interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin 23 p19 subunit; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; Interleukin12; interleukin-12 beta chain; interleukin-12 p40; interleukin-12 p40 subunit; Interleukin-12 subunit beta; interleukin-23 p19 subunit; Interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; natural killer cell stimulatory factor, 40 kD subunit; NK cell stimulatory factor chain 2; NKSF; NKSF2; P19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国