产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-12/IL-23 p40 Monoclonal Antibody (C15.6), eBioscience™
目录 :
14-7125-81
规格 :
50µg
价格 :
美国96.5
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
C15.6
反应物种 :
小鼠
应用 :
酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 9
出版应用/物种/样本/稀释 | 参考文献 |
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Couper K, Blount D, Hafalla J, Van Rooijen N, de Souza J, Riley E. Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia. Infect Immun. 2007;75:5806-18 pubmed
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Masek K, Fiore J, Leitges M, Yan S, Freedman B, Hunter C. Host cell Ca2+ and protein kinase C regulate innate recognition of Toxoplasma gondii. J Cell Sci. 2006;119:4565-73 pubmed
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Wysocka M, Kubin M, Vieira L, Ozmen L, Garotta G, Scott P, et al. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur J Immunol. 1995;25:672-6 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
IL-12/IL-23 p40 Monoclonal Antibody (C15.6), eBioscience™
目录# :
14-7125-81
规格 :
50µg
价格 :
美国96.5
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
ELISA:0.25-1微克/毫升
物种 :
小鼠
克隆 :
C15.6
抗体亚型 :
IgG1
储存 :
4° C
描述 :
IL-12 is an interleukin produced by dendritic cells, neutrophils, macrophages and human lymphoblastoid cells as a result of antigenic stimulation. IL-12 is a heterodimeric cytokine encoded by IL-12A (p35) and IL-12B (p40). IL-23 is a heterodimeric cytokine that shares a subunit with IL-12 (IL-12B) along with an IL-23A (IL-23p19) subunit. Functionally, IL-12 increases the expression of vascular endothelial adhesion molecule-1 on the endothelium, directs leukocytes towards tumors and facilitates the ischemic-hemorrhagic necrosis of the tumor tissue. In comparison, IL-23 plays an important role in stimulating memory T-cells, and is required for the induction, expansion, maintenance and downstream effector functions of Th17 cells, which play a vital role in upregulating neutrophil chemokines and various pro-inflammatory cytokines.
格式 :
液体
应用w/稀释 :
ELISA:0.25-1微克/毫升
别名 :
BOS_5471; BOS_8400; CLMF; CLMF p40; CLMF2; Cytotoxic lymphocyte maturation factor 40 kDa subunit; il 12; IL 12/IL 23p40; il 23; IL 23 p40; Il12; IL-12 subunit p40; IL12, subunit p40; Il12b; IL-12B; Il12p40; Il-12p40; il23; IL-23; IL23 p41; IL-23 subunit alpha; IL23A; IL-23A; IL-23-A; IL23P19; IL-23p19; ILN; IMD28; IMD29; Interleukin; Interleukin 12; interleukin 12 40kDa subunit; interleukin 12, p40; interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin 23 p19 subunit; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; Interleukin12; interleukin-12 beta chain; interleukin-12 p40; interleukin-12 p40 subunit; Interleukin-12 subunit beta; interleukin-23 p19 subunit; Interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; natural killer cell stimulatory factor, 40 kD subunit; NK cell stimulatory factor chain 2; NKSF; NKSF2; P19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798
更多信息或购买 :
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赛默飞世尔
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产品浏览
- IL-12/IL-23 p40 Monoclonal Antibody (C15.6), eBioscience™ | 14-7125-85
- IL-12/IL-23 p40 Monoclonal Antibody (C8.3), eBioscience™ | 14-7127-81
- IL-12 p35 Monoclonal Antibody (B-T21 (BT21)), eBioscience™ | 14-7128-82
- IL-12/IL-23 p40 Monoclonal Antibody (C8.6), eBioscience™ | 14-7129-81
- IL-12/IL-23 p40 Monoclonal Antibody (C8.6), eBioscience™ | 14-7129-85
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