产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-13 Monoclonal Antibody (PVM13-1), eBioscience™
目录 :
14-7139-81
规格 :
50µg
价格 :
美国108
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
PVM13-1
反应物种 :
人类
应用 :
酶联免疫吸附测定, 中和反应, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 5
Simpson L, Patel S, Bhakta N, Choy D, Brightbill H, Ren X, et al. A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production. Nat Immunol. 2014;15:1162-70 pubmed 出版商
Chang H, Liu G, Dwivedi N, Sun B, Okamoto Y, Kinslow J, et al. A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. JCI Insight. 2016;1:e90045 pubmed 出版商
Watkin L, Jessen B, Wiszniewski W, Vece T, Jan M, Sha Y, et al. COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. Nat Genet. 2015;47:654-60 pubmed 出版商
Price J, Haddon D, Kemmer D, Delepine G, Mandelbaum G, Jarrell J, et al. Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus. J Clin Invest. 2013;123:5135-45 pubmed 出版商
Fuschiotti P, Larregina A, Ho J, Feghali Bostwick C, Medsger T. Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis. Arthritis Rheum. 2013;65:236-46 pubmed 出版商
Hansmann L, Schmidl C, Kett J, Steger L, Andreesen R, Hoffmann P, et al. Dominant Th2 differentiation of human regulatory T cells upon loss of FOXP3 expression. J Immunol. 2012;188:1275-82 pubmed 出版商
Divekar A, Khanna D, Abtin F, Maranian P, Saggar R, Saggar R, et al. Treatment with imatinib results in reduced IL-4-producing T cells, but increased CD4(+) T cells in the broncho-alveolar lavage of patients with systemic sclerosis. Clin Immunol. 2011;141:293-303 pubmed 出版商
Medsger T, Ivanco D, Kardava L, Morel P, Lucas M, Fuschiotti P. GATA-3 up-regulation in CD8+ T cells as a biomarker of immune dysfunction in systemic sclerosis, resulting in excessive interleukin-13 production. Arthritis Rheum. 2011;63:1738-47 pubmed 出版商
Fuschiotti P, Medsger T, Morel P. Effector CD8+ T cells in systemic sclerosis patients produce abnormally high levels of interleukin-13 associated with increased skin fibrosis. Arthritis Rheum. 2009;60:1119-28 pubmed 出版商
Ma C, Chew G, Simpson N, Priyadarshi A, Wong M, Grimbacher B, et al. Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3. J Exp Med. 2008;205:1551-7 pubmed 出版商
Yuan L, Wen K, Azevedo M, Gonzalez A, Zhang W, Saif L. Virus-specific intestinal IFN-gamma producing T cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs. Vaccine. 2008;26:3322-31 pubmed 出版商
Schloot N, Meierhoff G, Karlsson Faresjö M, Ott P, Putnam A, Lehmann P, et al. Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop. J Autoimmun. 2003;21:365-76 pubmed
产品信息
产品类型 :
抗体
产品名称 :
IL-13 Monoclonal Antibody (PVM13-1), eBioscience™
目录# :
14-7139-81
规格 :
50µg
价格 :
美国108
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: 1-4 µg/mL, Flow Cytometry: Assay-Dependent, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent
物种 :
人类
克隆 :
PVM13-1
抗体亚型 :
IgG1
储存 :
4° C
描述 :
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
格式 :
液体
应用w/稀释 :
ELISA: 1-4 µg/mL, Flow Cytometry: Assay-Dependent, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent
别名 :
ALRH; ALRH antibody; BHR1; BOS_7773; il 13; Il13; Il-13; ILN; Interleukin; interleukin 13; Interleukin13; Interleukin-13; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国