产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IFN gamma Monoclonal Antibody (R4-6A2), eBioscience™
目录 :
14-7312-85
规格 :
500微克
价格 :
美国272
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
R4-6A2
反应物种 :
小鼠
应用 :
酶联免疫吸附测定, 中和反应, 抑制或激活实验
更多信息或购买 :
文章摘录数: 118
出版应用/物种/样本/稀释参考文献
  • 酶联免疫吸附测定; 小鼠; 图 5
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  • 酶联免疫吸附测定; 小鼠; 图 3a
Li L, Labuda J, Imai D, Griffey S, McSorley S. CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract. J Immunol. 2017;199:2547-2554 pubmed 出版商
  • 酶联免疫吸附测定; 小鼠; 图 s7a
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  • 酶联免疫吸附测定; 小鼠; 图 3D
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  • 酶联免疫吸附测定; 小鼠; 图 7
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  • 抑制或激活实验; 小鼠
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  • 酶联免疫吸附测定; 小鼠
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  • 酶联免疫吸附测定; 小鼠; 图 5
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Mutou Y, Ibuki Y, Kojima S. Immunomodulatory effects of ultraviolet B irradiation on atopic dermatitis in NC/Nga mice. Photodermatol Photoimmunol Photomed. 2007;23:135-44 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
IFN gamma Monoclonal Antibody (R4-6A2), eBioscience™
目录# :
14-7312-85
规格 :
500微克
价格 :
美国272
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Functional assay: Assay-Dependent, Neutralization: Assay-Dependent
物种 :
小鼠
克隆 :
R4-6A2
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines. Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. IFN gamma gene mutations are associated with aplastic anemia.
格式 :
液体
应用w/稀释 :
Functional assay: Assay-Dependent, Neutralization: Assay-Dependent
别名 :
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; Ifg; IFI; IFN gamma; IFN ?; IFNG; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国