产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Phospho-S6 (Ser235, Ser236) Monoclonal Antibody (cupk43k), eBioscience™
目录 :
14-9007-82
规格 :
100微克
价格 :
美国381
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
cupk43k
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 流式细胞仪
更多信息或购买 :
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 2
Alissafi T, Banos A, Boon L, Sparwasser T, Ghigo A, Wing K, et al. Tregs restrain dendritic cell autophagy to ameliorate autoimmunity. J Clin Invest. 2017;127:2789-2804 pubmed 出版商
Seipel K, Schmitter K, Bacher U, Pabst T. Rationale for a Combination Therapy Consisting of MCL1- and MEK-Inhibitors in Acute Myeloid Leukemia. Cancers (Basel). 2019;11: pubmed 出版商
Farmer J, Allard Chamard H, Sun N, Ahmad M, Bertocchi A, Mahajan V, et al. Induction of metabolic quiescence defines the transitional to follicular B cell switch. Sci Signal. 2019;12: pubmed 出版商
Wilski N, Del Casale C, Purwin T, Aplin A, Snyder C. Murine Cytomegalovirus Infection of Melanoma Lesions Delays Tumor Growth by Recruiting and Repolarizing Monocytic Phagocytes in the Tumor. J Virol. 2019;93: pubmed 出版商
Tanaka S, Pfleger C, Lai J, Roan F, Sun S, Ziegler S. KAP1 Regulates Regulatory T Cell Function and Proliferation in Both Foxp3-Dependent and -Independent Manners. Cell Rep. 2018;23:796-807 pubmed 出版商
Mittal P, Abblett R, Ryan J, Hagymasi A, Agyekum Yamoah A, Svedova J, et al. An Immunotherapeutic CD137 Agonist Releases Eomesodermin from ThPOK Repression in CD4 T Cells. J Immunol. 2018;200:1513-1526 pubmed 出版商
Yuan X, Yang B, Dong Y, Yamamura A, Fu W. CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells. elife. 2017;6: pubmed 出版商
Jastrzebski K, Hannan K, Tchoubrieva E, Hannan R, Pearson R. Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function. Growth Factors. 2007;25:209-26 pubmed
Shah O, Hunter T. Critical role of T-loop and H-motif phosphorylation in the regulation of S6 kinase 1 by the tuberous sclerosis complex. J Biol Chem. 2004;279:20816-23 pubmed
Peterson R, Schreiber S. Translation control: connecting mitogens and the ribosome. Curr Biol. 1998;8:R248-50 pubmed
Flotow H, Thomas G. Substrate recognition determinants of the mitogen-activated 70K S6 kinase from rat liver. J Biol Chem. 1992;267:3074-8 pubmed
产品信息
产品类型 :
抗体
产品名称 :
Phospho-S6 (Ser235, Ser236) Monoclonal Antibody (cupk43k), eBioscience™
目录# :
14-9007-82
规格 :
100微克
价格 :
美国381
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: Assay-Dependent, Western Blot: 1:1000
物种 :
人类, 小鼠
克隆 :
cupk43k
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent, Western Blot: 1:1000
别名 :
(Rp)S6; 40S ribosomal protein S6; air[8]; air8; anon-WO02059370.61; CG10944; CG10944 gene product from transcript CG10944-RB; CG10944-PA; CG10944-PB; Dmel CG10944; Dmel_CG10944; DS6; hemocytes enlarged; hen; l(1)air[8]; l(1)air8; l(1)hen; lethal(1)aberrant immune response[8]; lethal-(1)-haemocytes enlarged; lethal-aberrant-immune-response-8; M(1)7BC; M(1)7C; minute; minute (1) 7BC; OK/SW-cl.2; OTTHUMP00000021121; OTTHUMP00000021122; Phosphoprotein NP33; pp30; ribosomal protein S6; Rp S6; RP11-513M16.6; RPS6; RpS6-PA; RpS6-PB; RS6; S6; S6 ribosomal protein; S6R; Small ribosomal subunit protein eS6; wu:fa92e06; wu:fb64g06; zgc:92237
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国