产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Lamin A/C Monoclonal Antibody (4A7), eBioscience
目录 :
14-9688-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4A7
反应物种 :
中国人仓鼠, 人类, 小鼠, domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 5
参考文献
Shah S, Molinaro G, Liu B, Wang R, Huber K, Richter J. FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism. Cell Rep. 2020;30:4459-4472.e6 pubmed 出版商
Zuela N, Bar D, Gruenbaum Y. Lamins in development, tissue maintenance and stress. EMBO Rep. 2012;13:1070-8 pubmed 出版商
Jung H, Lee J, Yang S, Young S, Fong L. Nuclear lamins in the brain - new insights into function and regulation. Mol Neurobiol. 2013;47:290-301 pubmed 出版商
Navarro C, De Sandre Giovannoli A, Bernard R, Boccaccio I, Boyer A, Genevieve D, et al. Lamin A and ZMPSTE24 (FACE-1) defects cause nuclear disorganization and identify restrictive dermopathy as a lethal neonatal laminopathy. Hum Mol Genet. 2004;13:2493-503 pubmed
Manilal S, Randles K, Aunac C, Nguyen M, Morris G. A lamin A/C beta-strand containing the site of lipodystrophy mutations is a major surface epitope for a new panel of monoclonal antibodies. Biochim Biophys Acta. 2004;1671:87-92 pubmed
产品信息
产品类型 :
抗体
产品名称 :
Lamin A/C Monoclonal Antibody (4A7), eBioscience
目录# :
14-9688-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
仓鼠, 人类, 小鼠, 兔
应用 :
ELISA: Assay-dependent, Flow Cytometry: 10 µg/mL, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
物种 :
仓鼠, 人类, 小鼠, 兔
克隆 :
4A7
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Flow Cytometry: 10 µg/mL, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
别名 :
70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国