产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PAR2 Monoclonal Antibody (SAM11), eBioscience
目录 :
14-9699-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SAM11
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 7
参考文献
Sitaras N, Rivera J, Noueihed B, Bien Aimé M, Zaniolo K, Omri S, et al. Retinal neurons curb inflammation and enhance revascularization in ischemic retinopathies via proteinase-activated receptor-2. Am J Pathol. 2015;185:581-95 pubmed 出版商
Adams M, Pagel C, Mackie E, Hooper J. Evaluation of antibodies directed against human protease-activated receptor-2. Naunyn Schmiedebergs Arch Pharmacol. 2012;385:861-73 pubmed 出版商
Arizmendi N, Abel M, Puttagunta L, Asaduzzaman M, Davidson C, Karimi K, et al. Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation. Allergy Asthma Clin Immunol. 2011;7:22 pubmed 出版商
Frateschi S, Camerer E, Crisante G, Rieser S, Membrez M, Charles R, et al. PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin. Nat Commun. 2011;2:161 pubmed
Kaufmann R, Oettel C, Horn A, Halbhuber K, Eitner A, Krieg R, et al. Met receptor tyrosine kinase transactivation is involved in proteinase-activated receptor-2-mediated hepatocellular carcinoma cell invasion. Carcinogenesis. 2009;30:1487-96 pubmed 出版商
Bocheva G, Rattenholl A, Kempkes C, Goerge T, Lin C, D Andrea M, et al. Role of matriptase and proteinase-activated receptor-2 in nonmelanoma skin cancer. J Invest Dermatol. 2009;129:1816-23 pubmed 出版商
Buddenkotte J, Stroh C, Engels I, Moormann C, Shpacovitch V, Seeliger S, et al. Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B. J Invest Dermatol. 2005;124:38-45 pubmed
产品信息
产品类型 :
抗体
产品名称 :
PAR2 Monoclonal Antibody (SAM11), eBioscience
目录# :
14-9699-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1:250
物种 :
人类
克隆 :
SAM11
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
格式 :
液体
应用w/稀释 :
ELISA: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1:250
别名 :
coagulation factor II (thrombin) receptor-like 1; coagulation factor II receptor-like 1; F2R like trypsin receptor 1; F2RL1; Gpcr11; Gpr11; G-protein coupled receptor 11; PAR2; PAR-2; protease-activated receptor 2; Protease-activated receptor-2; proteinase-activated receptor 2; Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2; proteinase-activated receptor-2; Proteinase-activated receptor-2 G protein-coupled receptor 11; Proteinase-activated receptor-2, G protein-coupled receptor 11; thrombin receptor-like 1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国