产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PAR2 Monoclonal Antibody (SAM11), eBioscience
目录 :
14-9699-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SAM11
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 7
参考文献 |
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Frateschi S, Camerer E, Crisante G, Rieser S, Membrez M, Charles R, et al. PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin. Nat Commun. 2011;2:161 pubmed
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Buddenkotte J, Stroh C, Engels I, Moormann C, Shpacovitch V, Seeliger S, et al. Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B. J Invest Dermatol. 2005;124:38-45 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
PAR2 Monoclonal Antibody (SAM11), eBioscience
目录# :
14-9699-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1:250
物种 :
人类
克隆 :
SAM11
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
格式 :
液体
应用w/稀释 :
ELISA: Assay-Dependent, Functional Assay: Assay-Dependent, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1:250
别名 :
coagulation factor II (thrombin) receptor-like 1; coagulation factor II receptor-like 1; F2R like trypsin receptor 1; F2RL1; Gpcr11; Gpr11; G-protein coupled receptor 11; PAR2; PAR-2; protease-activated receptor 2; Protease-activated receptor-2; proteinase-activated receptor 2; Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2; proteinase-activated receptor-2; Proteinase-activated receptor-2 G protein-coupled receptor 11; Proteinase-activated receptor-2, G protein-coupled receptor 11; thrombin receptor-like 1
更多信息或购买 :
公司信息
赛默飞世尔
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