产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Glucagon Monoclonal Antibody (ICACLS), eBioscience
目录 :
14-9743-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
ICACLS
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 5
参考文献
Norman D, Drott C, Carlsson P, Espes D. Irisin-A Pancreatic Islet Hormone. Biomedicines. 2022;10: pubmed 出版商
Liu Z, Ding Z, Lynch E, McCauley N, Zhou Y, Zhang K, et al. Pregestational diet transition to normal-fat diet avoids the deterioration of pancreatic β-cell function in male offspring induced by maternal high-fat diet. J Nutr Biochem. 2020;86:108495 pubmed 出版商
Taborsky G. The physiology of glucagon. J Diabetes Sci Technol. 2010;4:1338-44 pubmed
Sloop K, Michael M, Moyers J. Glucagon as a target for the treatment of Type 2 diabetes. Expert Opin Ther Targets. 2005;9:593-600 pubmed
Jiang G, Zhang B. Glucagon and regulation of glucose metabolism. Am J Physiol Endocrinol Metab. 2003;284:E671-8 pubmed
产品信息
产品类型 :
抗体
产品名称 :
Glucagon Monoclonal Antibody (ICACLS), eBioscience
目录# :
14-9743-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫组化(石蜡):0.1微克/毫升
物种 :
人类, 小鼠, 大鼠
克隆 :
ICACLS
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
Glucagon is a 29-residue polypeptide hormone (MW 3482), produced in the pancreas. A related hormone, enteroglucagon (or oxyntomodulin), which is produced in the mucosa of the small and large intestine, consists of the 29 amino acid sequence of pancreatic glucagon extended by 8 additional residues at the C-terminus. The biological activities of pancreatic glucagon include glycogenolysis, lipolysis, gluconeogenesis, and ketogensis, which are antagonistic effects to those of insulin action, thus leading to increased blood glucose levels. Immunocytochemical studies have revealed the presence of pancreatic glucagon inside the A or alpha cells, which constitute 15-20% of the islet cell population. These cells are located preferentially at the periphery of the human pancreatic islets. Pathological manifestations of the glucagon-type peptide residue almost exclusively with the exsistence of tumors or glucagonomas, as no states of glucagon-cell deficiency or hyperplasia have been identified. Glucagon-specific antibodies would prove useful as a cell and tumor markers applying immunohistochemical techniques, and as an analytical tool in qualification of the hormone.
格式 :
液体
应用w/稀释 :
免疫组化(石蜡):0.1微克/毫升
别名 :
GCG; Glicentin; Glicentin-related polypeptide; GLP1; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP1/2; GLP2; GLP-2; Glu; glucagon; Glucagon-like peptide 1; Glucagon-like peptide 1(7-36); Glucagon-like peptide 1(7-37); Glucagon-like peptide 2; glucagon-like peptide-1; GRPP; IL12p35; IL12P40; Incretin hormone; OXM; OXY; Oxyntomodulin; porcine proglucagon; PPG; preproglucagon; proglucagon
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国