产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Insulin Monoclonal Antibody (ICBTACLS), eBioscience™
目录 :
14-9769-82
规格 :
100µg
价格 :
美国345
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
ICBTACLS
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 4
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:400; 图 1a
Anquetil F, Mondanelli G, Gonzalez N, Rodríguez Calvo T, Zapardiel Gonzalo J, Krogvold L, et al. Loss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 Diabetes. Diabetes. 2018;67:1858-1866 pubmed 出版商
Abdelrazek H, Kilany O, Muhammad M, Tag H, Abdelazim A. Black Seed Thymoquinone Improved Insulin Secretion, Hepatic Glycogen Storage, and Oxidative Stress in Streptozotocin-Induced Diabetic Male Wistar Rats. Oxid Med Cell Longev. 2018;2018:8104165 pubmed 出版商
Banks W, Owen J, Erickson M. Insulin in the brain: there and back again. Pharmacol Ther. 2012;136:82-93 pubmed 出版商
Gillespie K. Type 1 diabetes: pathogenesis and prevention. CMAJ. 2006;175:165-70 pubmed
产品信息
产品类型 :
抗体
产品名称 :
Insulin Monoclonal Antibody (ICBTACLS), eBioscience™
目录# :
14-9769-82
规格 :
100µg
价格 :
美国345
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunohistochemistry (Paraffin): 0.25 µg/mL, Western Blot: 5 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
ICBTACLS
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 0.25 µg/mL, Western Blot: 5 µg/mL
别名 :
AA986540; BOS_25069; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2; Ins-2; Ins2-rs1; InsII; Insulin; insulin 1; insulin 2; Insulin A chain; Insulin B chain; insulin I; insulin II; Insulin-1; Insulin-1 A chain; Insulin-1 B chain; Insulin-2; Insulin-2 A chain; Insulin-2 B chain; IRDN; Mody; MODY10; Mody4; preproinsulin; proinsulin
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国