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抗体

Placental Alkaline Phosphatase Monoclonal Antibody (8B6), eBioscience™

14-9870-37

2毫克

1200.00美元

单克隆

小鼠

AP

8B6

酶联免疫吸附测定, 免疫组化, 免疫组化-石蜡切片, 免疫组化-冰冻切片

Placental Alkaline Phosphatase Monoclonal Antibody (8B6), eBioscience™

14-9870-37

2毫克

1200.00美元

单克隆

亲和色谱

小鼠

人类

ELISA:依实验方法而定, 免疫组化(冷冻):5微克/毫升, 免疫组化(石蜡):5微克/毫升

人类

8B6

IgG2a, kappa

4° C

Placental Alkaline Phosphatase plays an important role in the regulation of specific inflammatory disease processes. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney for this form of alkaline phosphatase have been well characterized. Placental Alkaline Phosphatase reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. Placental Alkaline Phosphatase is useful in the identification of testicular germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA). A proposed function of Placental Alkaline Phosphatase is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. Placental Alkaline Phosphatase has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of hypophosphatasia can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.

液体

ELISA:依实验方法而定, 免疫组化(冷冻):5微克/毫升, 免疫组化(石蜡):5微克/毫升

Alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; ALPP; AP-TNAP; DOA1; FLJ11281; FLJ40094; FLJ61142; FLJ93059; glycerophosphatase; HOPS; MGC161443; MGC167935; P PLAP; PALP; PLA2P; PLAA; Placental alkaline phosphatase 1; PLAP; PLAP-1; Regan isozyme; TNAP; TNSALP