产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
P-cadherin Monoclonal Antibody (12H6), eBioscience™
目录 :
14-9873-82
规格 :
100微克
价格 :
美国350
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
12H6
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 5
参考文献
Brueggmann D, Templeman C, Starzinski Powitz A, Rao N, Gayther S, Lawrenson K. Novel three-dimensional in vitro models of ovarian endometriosis. J Ovarian Res. 2014;7:17 pubmed 出版商
Jacobs K, Feys L, Vanhoecke B, Van Marck V, Bracke M. P-cadherin expression reduces melanoma growth, invasion, and responsiveness to growth factors in nude mice. Eur J Cancer Prev. 2011;20:207-16 pubmed 出版商
Turashvili G, McKinney S, Goktepe O, Leung S, Huntsman D, Gelmon K, et al. P-cadherin expression as a prognostic biomarker in a 3992 case tissue microarray series of breast cancer. Mod Pathol. 2011;24:64-81 pubmed 出版商
Sarrio D, Palacios J, Hergueta Redondo M, Gomez Lopez G, Cano A, Moreno Bueno G. Functional characterization of E- and P-cadherin in invasive breast cancer cells. BMC Cancer. 2009;9:74 pubmed 出版商
Paredes J, Correia A, Ribeiro A, Albergaria A, Milanezi F, Schmitt F. P-cadherin expression in breast cancer: a review. Breast Cancer Res. 2007;9:214 pubmed
产品信息
产品类型 :
抗体
产品名称 :
P-cadherin Monoclonal Antibody (12H6), eBioscience™
目录# :
14-9873-82
规格 :
100微克
价格 :
美国350
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: Assay-Dependent
物种 :
人类
克隆 :
12H6
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily. Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin. Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium. P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle. Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas. Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: Assay-Dependent
别名 :
AI385538; CADH3; cadherin 15, M-cadherin (myotubule); cadherin 3; cadherin 3, type 1, P-cadherin (placental); cadherin-3; Cadp; calcium-dependent adhesion protein, placental; CDH15; CDH3; CDHP; HJMD; PCAD; P-cadherin; Placental cadherin; Placental-cadherin; RPE-specific cadherin
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国