产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD278 (ICOS) Monoclonal Antibody (C398.4A), eBioscience™
目录 :
14-9949-82
规格 :
100微克
价格 :
美国204
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
未共轭
克隆名称 :
C398.4A
反应物种 :
小鼠, 大鼠, 猕猴
应用 :
免疫组化, 免疫沉淀, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 40
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| Nakae S, Iwakura Y, Suto H, Galli S. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81:1258-68 pubmed
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| Onlamoon N, Hudson K, Bryan P, Mayne A, Bonyhadi M, Berenson R, et al. Optimization of in vitro expansion of macaque CD4 T cells using anti-CD3 and co-stimulation for autotransfusion therapy. J Med Primatol. 2006;35:178-93 pubmed
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| Smith P, Walsh C, Mangan N, Fallon R, Sayers J, McKenzie A, et al. Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages. J Immunol. 2004;173:1240-8 pubmed
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Li X, Acuff N, Peeks A, Kirkland R, Wyatt K, Nagy T, et al. Tumor Progression Locus 2 (Tpl2) Activates the Mammalian Target of Rapamycin (mTOR) Pathway, Inhibits Forkhead Box P3 (FoxP3) Expression, and Limits Regulatory T Cell (Treg) Immunosuppressive Functions. J Biol Chem. 2016;291:16802-15 pubmed 出版商
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Arimura Y, Shiroki F, Kuwahara S, Kato H, Dianzani U, Uchiyama T, et al. Akt is a neutral amplifier for Th cell differentiation. J Biol Chem. 2004;279:11408-16 pubmed
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Lucia M, Buonfiglio D, Bottarel F, Bensi T, Rutella S, Rumi C, et al. Expression of the novel T cell activation molecule hpH4 in HIV-infected patients: correlation with disease status. AIDS Res Hum Retroviruses. 2000;16:549-57 pubmed
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Buonfiglio D, Bragardo M, Bonissoni S, Redoglia V, Cauda R, Zupo S, et al. Characterization of a novel human surface molecule selectively expressed by mature thymocytes, activated T cells and subsets of T cell lymphomas. Eur J Immunol. 1999;29:2863-74 pubmed
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Redoglia V, Dianzani U, Rojo J, Portoles P, Bragardo M, Wolff H, et al. Characterization of H4: a mouse T lymphocyte activation molecule functionally associated with the CD3/T cell receptor. Eur J Immunol. 1996;26:2781-9 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD278 (ICOS) Monoclonal Antibody (C398.4A), eBioscience™
目录# :
14-9949-82
规格 :
100微克
价格 :
美国204
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
亚美尼亚仓鼠
反应物种 :
小鼠, 大鼠, 猕猴
应用 :
Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent
物种 :
小鼠, 大鼠, 猕猴
克隆 :
C398.4A
抗体亚型 :
IgG
储存 :
4° C
描述 :
CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test, Functional assay: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent
别名 :
Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
更多信息或购买 :
公司信息
赛默飞世尔
产品浏览
- HLA-E Monoclonal Antibody (3D12HLA-E), eBioscience™ | 14-9953-82
- HLA-DR Monoclonal Antibody (LN3), eBioscience™ | 14-9956-80
- HLA-DR Monoclonal Antibody (LN3), eBioscience™ | 14-9956-82
- HLA-G Monoclonal Antibody (87G), eBioscience™ | 14-9957-82
- MHC I Free Chain Monoclonal Antibody (A4), eBioscience™ | 14-9958-82
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