产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD2 Monoclonal Antibody (RPA-2.10), PE-Cyanine5, eBioscience™
目录 :
15-0029-42
规格 :
100试验
价格 :
美国330
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE-Cy5
克隆名称 :
RPA-2.10
反应物种 :
baboon , 食蟹猴, 人类, 黑猩猩, pigs , 猕猴
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 5
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类
Park C, Majeti R, Weissman I. In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood. Nat Protoc. 2008;3:1932-40 pubmed 出版商
Wang K, Guzman A, Yan Z, Zhang S, Hu M, Hamaneh M, et al. Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells. Cell Rep. 2019;26:2580-2592.e7 pubmed 出版商
Felce J, MacRae A, Davis S. Constraints on GPCR Heterodimerization Revealed by the Type-4 Induced-Association BRET Assay. Biophys J. 2019;116:31-41 pubmed 出版商
Okoye Okafor U, Bartholdy B, Cartier J, Gao E, Pietrak B, Rendina A, et al. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015;11:878-86 pubmed 出版商
Kap Y, van Meurs M, van Driel N, Koopman G, Melief M, Brok H, et al. A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. J Histochem Cytochem. 2009;57:1159-67 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD2 Monoclonal Antibody (RPA-2.10), PE-Cyanine5, eBioscience™
目录# :
15-0029-42
规格 :
100试验
价格 :
美国330
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human primate, Porcine, Rhesus Monkey
应用 :
Flow Cytometry: 5 µL (0.06 µg)/test
物种 :
Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human primate, Porcine, Rhesus Monkey
克隆 :
RPA-2.10
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells. CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it. The interaction between CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection. Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.06 µg)/test
别名 :
CD2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; Cd2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; Lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国