产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD3 Monoclonal Antibody (17A2), Functional Grade, eBioscience
目录 :
16-0032-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
17A2
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 305
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 s2b
Fahy N, Palomares Cabeza V, Lolli A, Witte Bouma J, Merino A, Ridwan Y, et al. Chondrogenically Primed Human Mesenchymal Stem Cells Persist and Undergo Early Stages of Endochondral Ossification in an Immunocompetent Xenogeneic Model. Front Immunol. 2021;12:715267 pubmed 出版商
  • 抑制或激活实验; 小鼠
Akgul A, Maddaloni M, Jun S, Nelson A, Odreman V, Hoffman C, et al. Stimulation of regulatory T cells with Lactococcus lactis expressing enterotoxigenic E. coli colonization factor antigen 1 retains salivary flow in a genetic model of Sjögren's syndrome. Arthritis Res Ther. 2021;23:99 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4g
Harbour S, DiToro D, Witte S, Zindl C, Gao M, Schoeb T, et al. TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity. Sci Immunol. 2020;5: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5a
Williams G, Marmion D, Schonhoff A, Jurkuvenaite A, Won W, Standaert D, et al. T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease. Acta Neuropathol. 2020;139:855-874 pubmed 出版商
  • 流式细胞仪; 小鼠
Sanz Ortega L, Rojas J, Portilla Y, Pérez Yagüe S, Barber D. Magnetic Nanoparticles Attached to the NK Cell Surface for Tumor Targeting in Adoptive Transfer Therapies Does Not Affect Cellular Effector Functions. Front Immunol. 2019;10:2073 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 e2n
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 1a
Hu K, Huang Q, Liu C, Li Y, Liu Y, Wang H, et al. c-Jun/Bim Upregulation in Dopaminergic Neurons Promotes Neurodegeneration in the MPTP Mouse Model of Parkinson's Disease. Neuroscience. 2019;399:117-124 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3a
Sharma D, Malik A, Guy C, Vogel P, Kanneganti T. TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy. J Clin Invest. 2019;129:150-162 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Jensen I, Winborn C, Fosdick M, Shao P, Tremblay M, Shan Q, et al. Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections. PLoS Pathog. 2018;14:e1007405 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6c
  • 流式细胞仪; 小鼠; 图 6b
Brun P, Scarpa M, Marchiori C, Conti J, Kotsafti A, Porzionato A, et al. Herpes Simplex Virus Type 1 Engages Toll Like Receptor 2 to Recruit Macrophages During Infection of Enteric Neurons. Front Microbiol. 2018;9:2148 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Cheng Y, Zhu X, Wang X, Zhuang Q, Huyan X, Sun X, et al. Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation. Front Immunol. 2018;9:1566 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 s3b
Baens M, Stirparo R, Lampi Y, Verbeke D, Vandepoel R, Cools J, et al. Malt1 self-cleavage is critical for regulatory T cell homeostasis and anti-tumor immunity in mice. Eur J Immunol. 2018;48:1728-1738 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Abel A, Tiwari A, Gerbec Z, Siebert J, Yang C, Schloemer N, et al. IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. Front Immunol. 2018;9:1168 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Hu X, Majchrzak K, Liu X, Wyatt M, Spooner C, Moisan J, et al. In Vitro Priming of Adoptively Transferred T Cells with a RORγ Agonist Confers Durable Memory and Stemness In Vivo. Cancer Res. 2018;78:3888-3898 pubmed 出版商
  • 流式细胞仪; 人类; 图 5e
Li C, Psatha N, Wang H, Singh M, Samal H, Zhang W, et al. Integrating HDAd5/35++ Vectors as a New Platform for HSC Gene Therapy of Hemoglobinopathies. Mol Ther Methods Clin Dev. 2018;9:142-152 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 1b
Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch S, et al. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018;128:1852-1866 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 5a
Vigolo M, Chambers M, Willen L, Chevalley D, Maskos K, Lammens A, et al. A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors. Nat Commun. 2018;9:1199 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine T, et al. Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression. J Clin Invest. 2018;128:2487-2499 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2b
Macdougall C, Wood E, Loschko J, Scagliotti V, Cassidy F, Robinson M, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metab. 2018;27:588-601.e4 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4f
Chennupati V, Veiga D, Maslowski K, Andina N, Tardivel A, Yu E, et al. Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation. J Clin Invest. 2018;128:1597-1614 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400
Mao A, Ishizuka I, Kasal D, Mandal M, Bendelac A. A shared Runx1-bound Zbtb16 enhancer directs innate and innate-like lymphoid lineage development. Nat Commun. 2017;8:863 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 6e
He W, Wang C, Mu R, Liang P, Huang Z, Zhang J, et al. MiR-21 is required for anti-tumor immune response in mice: an implication for its bi-directional roles. Oncogene. 2017;36:4212-4223 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Wang S, Xia P, Chen Y, Huang G, Xiong Z, Liu J, et al. Natural Killer-like B Cells Prime Innate Lymphocytes against Microbial Infection. Immunity. 2016;45:131-44 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s4
  • 免疫组化; 人类; 1:100; 图 s3
Li Z, Hodgkinson T, Gothard E, Boroumand S, Lamb R, Cummins I, et al. Epidermal Notch1 recruits RORγ(+) group 3 innate lymphoid cells to orchestrate normal skin repair. Nat Commun. 2016;7:11394 pubmed 出版商
  • 流式细胞仪; 小鼠
Tagliamonte M, Petrizzo A, Napolitano M, Luciano A, Rea D, Barbieri A, et al. A novel multi-drug metronomic chemotherapy significantly delays tumor growth in mice. J Transl Med. 2016;14:58 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Gallego Ortega D, Ledger A, Roden D, Law A, Magenau A, Kikhtyak Z, et al. ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells. PLoS Biol. 2015;13:e1002330 pubmed 出版商
  • 免疫组化; 小鼠; 图 1
Egan C, Sodhi C, Good M, Lin J, Jia H, Yamaguchi Y, et al. Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis. J Clin Invest. 2016;126:495-508 pubmed
  • 免疫组化; 小鼠; 1:500
Yeung H, Lo P, Ng D, Fong W. Anti-tumor immunity of BAM-SiPc-mediated vascular photodynamic therapy in a BALB/c mouse model. Cell Mol Immunol. 2017;14:223-234 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
Littwitz Salomon E, Akhmetzyanova I, Vallet C, Francois S, Dittmer U, Gibbert K. Activated regulatory T cells suppress effector NK cell responses by an IL-2-mediated mechanism during an acute retroviral infection. Retrovirology. 2015;12:66 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Saulep Easton D, Vincent F, Quah P, Wei A, Ting S, Croce C, et al. The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells. Leukemia. 2016;30:163-72 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 1
Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523:337-41 pubmed 出版商
  • 抑制或激活实验; 小鼠
Sharma S, Chintala N, Vadrevu S, Patel J, Karbowniczek M, Markiewski M. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J Immunol. 2015;194:5529-38 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Wensveen F, Jelenčić V, Valentić S, Å estan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Buchwald Z, Yang C, Nellore S, Shashkova E, Davis J, Cline A, et al. A Bone Anabolic Effect of RANKL in a Murine Model of Osteoporosis Mediated Through FoxP3+ CD8 T Cells. J Bone Miner Res. 2015;30:1508-22 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Evrard M, Chong S, Devi S, Chew W, Lee B, Poidinger M, et al. Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L-/- reporter mouse by multiphoton intravital microscopy. J Leukoc Biol. 2015;97:611-9 pubmed 出版商
  • 流式细胞仪; 小鼠
Yin Y, Qin T, Wang X, Lin J, Yu Q, Yang Q. CpG DNA assists the whole inactivated H9N2 influenza virus in crossing the intestinal epithelial barriers via transepithelial uptake of dendritic cell dendrites. Mucosal Immunol. 2015;8:799-814 pubmed 出版商
  • 流式细胞仪; 人类; 图 2
Svatek R, Zhao X, Morales E, Jha M, Tseng T, Hugen C, et al. Sequential intravesical mitomycin plus Bacillus Calmette-Guérin for non-muscle-invasive urothelial bladder carcinoma: translational and phase I clinical trial. Clin Cancer Res. 2015;21:303-11 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Fahl S, Harris B, Coffey F, Wiest D. Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint. J Immunol. 2015;194:200-9 pubmed
  • 流式细胞仪; 小鼠
Baptista A, Roozendaal R, Reijmers R, Koning J, Unger W, Greuter M, et al. Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation. elife. 2014;3: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s5
Knoop K, McDonald K, McCrate S, McDole J, Newberry R. Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon. Mucosal Immunol. 2015;8:198-210 pubmed 出版商
  • 流式细胞仪; 小鼠
Boyoglu Barnum S, Chirkova T, Todd S, Barnum T, Gaston K, Jorquera P, et al. Prophylaxis with a respiratory syncytial virus (RSV) anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice. J Virol. 2014;88:10569-83 pubmed 出版商
  • 流式细胞仪; 小鼠
Zhou Q, Ho A, Schlitzer A, Tang Y, Wong K, Wong F, et al. GM-CSF-licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis. J Immunol. 2014;193:496-509 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Dupont C, Christian D, Selleck E, Pepper M, Leney Greene M, Harms Pritchard G, et al. Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii. PLoS Pathog. 2014;10:e1004047 pubmed 出版商
  • 免疫细胞化学; 人类; 表 2
Koga T, Hedrich C, Mizui M, Yoshida N, Otomo K, Lieberman L, et al. CaMK4-dependent activation of AKT/mTOR and CREM-? underlies autoimmunity-associated Th17 imbalance. J Clin Invest. 2014;124:2234-45 pubmed 出版商
  • 流式细胞仪; 小鼠
Murphy K, Erickson J, Johnson C, Seiler C, Bedi J, Hu P, et al. CD8+ T cell-independent tumor regression induced by Fc-OX40L and therapeutic vaccination in a mouse model of glioma. J Immunol. 2014;192:224-33 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Nussbaum J, Van Dyken S, von Moltke J, Cheng L, Mohapatra A, Molofsky A, et al. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature. 2013;502:245-8 pubmed 出版商
  • 流式细胞仪; 人类; 图 s9
Daigneault M, de Silva T, Bewley M, Preston J, Marriott H, Mitchell A, et al. Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. PLoS Pathog. 2012;8:e1002814 pubmed 出版商
  • 流式细胞仪; 小鼠
Loebbermann J, Schnoeller C, Thornton H, Durant L, Sweeney N, Schuijs M, et al. IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice. PLoS ONE. 2012;7:e32371 pubmed 出版商
  • 流式细胞仪; 小鼠
Randall K, Chan S, Ma C, Fung I, Mei Y, Yabas M, et al. DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice. J Exp Med. 2011;208:2305-20 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Galand C, Donnou S, Crozet L, Brunet S, Touitou V, Ouakrim H, et al. Th17 cells are involved in the local control of tumor progression in primary intraocular lymphoma. PLoS ONE. 2011;6:e24622 pubmed 出版商
  • 流式细胞仪; 小鼠
Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood. 2008;111:142-9 pubmed
Elsayed R, Elashiry M, Liu Y, Morandini A, El Awady A, Elashiry M, et al. Microbially-Induced Exosomes from Dendritic Cells Promote Paracrine Immune Senescence: Novel Mechanism of Bone Degenerative Disease in Mice. Aging Dis. 2023;14:136-151 pubmed 出版商
Li H, Hu M, Huang Z, Wang Y, Xu Y, Deng J, et al. A single-cell atlas reveals the heterogeneity of meningeal immunity in a mouse model of Methyl CpG binding protein 2 deficiency. Front Immunol. 2022;13:1056447 pubmed 出版商
Xu Y, Cao L, Ji S, Shen W. LncRNA ANRIL-mediated miR-181b-5p/S1PR1 axis is involved in the progression of uremic cardiomyopathy through activating T cells. Sci Rep. 2022;12:18027 pubmed 出版商
Zhang Y, Chang Y, Han Z, Ma K, Zeng X, Li L. Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance. Dis Markers. 2022;2022:7812099 pubmed 出版商
Banerjee A, Li D, Guo Y, Mei Z, Lau C, Chen K, et al. A reengineered common chain cytokine augments CD8+ T cell-dependent immunotherapy. JCI Insight. 2022;7: pubmed 出版商
Yan Q, Gao H, Yao Q, Ling K, Xiao G. Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling. J Biol Chem. 2022;298:101639 pubmed 出版商
Uhl F, Vanherle L, Matthes F, Meissner A. Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure. Int J Mol Sci. 2022;23: pubmed 出版商
Ramavath N, Gadipudi L, Provera A, Gigliotti L, Boggio E, Bozzola C, et al. Inducible T-Cell Costimulator Mediates Lymphocyte/Macrophage Interactions During Liver Repair. Front Immunol. 2021;12:786680 pubmed 出版商
Trofimova O, Korotkaja K, Skrastina D, Jansons J, Spunde K, Isaguliants M, et al. Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model. Vaccines (Basel). 2021;9: pubmed 出版商
Saito T, Sako Y, Sato Kaneko F, Hosoya T, Yao S, Lao F, et al. Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge. Front Immunol. 2021;12:701445 pubmed 出版商
Al Delbany D, Robert V, Dubois Vedrenne I, Del Prete A, Vernimmen M, Radi A, et al. Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis. Cancers (Basel). 2021;13: pubmed 出版商
Fitzgerald B, Connolly K, Cui C, Fagerberg E, Mariuzza D, Hornick N, et al. A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma. Cell Rep Methods. 2021;1: pubmed 出版商
Tello Rubio B, Bugault F, Baudon B, Raynal B, Br xfb l xe9 S, Morel J, et al. Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone. Front Pharmacol. 2021;12:733496 pubmed 出版商
Liu J, Liu Y, Panda S, Liu A, Lei J, Burd I. Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation. Front Immunol. 2021;12:718563 pubmed 出版商
Medina C, Chiu Y, Stremska M, Lucas C, Poon I, Tung K, et al. Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation. Immunity. 2021;54:1715-1727.e7 pubmed 出版商
Ng K, Delaney P, Thenet D, Murtough S, Webb C, Zaman N, et al. Early inflammation precedes cardiac fibrosis and heart failure in desmoglein 2 murine model of arrhythmogenic cardiomyopathy. Cell Tissue Res. 2021;386:79-98 pubmed 出版商
Cheng C, Tan H, Wang N, Chen L, Meng Z, Chen Z, et al. Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression. Clin Transl Med. 2021;11:e467 pubmed 出版商
Jin J, Kim C, Xia Q, Gould T, Cao W, Zhang H, et al. Activation of mTORC1 at late endosomes misdirects T cell fate decision in older individuals. Sci Immunol. 2021;6: pubmed 出版商
Yu X, Zhou G, Shao B, Zhou H, Xu C, Yan F, et al. Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice. Front Microbiol. 2021;12:647304 pubmed 出版商
Peng J, Xiao Y, Yang Q, Liu Q, Chen Y, Shi K, et al. Intracellular aggregation of peptide-reprogrammed small molecule nanoassemblies enhances cancer chemotherapy and combinatorial immunotherapy. Acta Pharm Sin B. 2021;11:1069-1082 pubmed 出版商
Agalave N, Mody P, Szabo Pardi T, Jeong H, Burton M. Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy. Front Immunol. 2021;12:642420 pubmed 出版商
Chen J, Ding Y, Huang F, Lan R, Wang Z, Huang W, et al. Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells. Oncol Lett. 2021;21:409 pubmed 出版商
Vonderhaar E, Barnekow N, McAllister D, McOlash L, Eid M, Riese M, et al. STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer. Cell Mol Gastroenterol Hepatol. 2021;12:41-58 pubmed 出版商
Mardomi A, Limoni S, Rahbarghazi R, Mohammadi N, Khorashadizadeh M, Ranjbaran H, et al. PD-L1 overexpression conveys tolerance of mesenchymal stem cell-derived cardiomyocyte-like cells in an allogeneic mouse model. J Cell Physiol. 2021;236:6328-6343 pubmed 出版商
Pierini S, Tanyi J, Simpkins F, George E, Uribe Herranz M, Drapkin R, et al. Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target. JCI Insight. 2020;5: pubmed 出版商
Lan Q, Chen Y, Dai C, Li S, Fei X, Dong J, et al. Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model. Cancer Sci. 2020;111:3626-3638 pubmed 出版商
Jin J, Li X, Hu B, Kim C, Cao W, Zhang H, et al. FOXO1 deficiency impairs proteostasis in aged T cells. Sci Adv. 2020;6:eaba1808 pubmed 出版商
Luo Z, Liao T, Zhang Y, Zheng H, Sun Q, Han F, et al. Triptolide Attenuates Transplant Vasculopathy Through Multiple Pathways. Front Immunol. 2020;11:612 pubmed 出版商
Gautam J, Xu L, Nirwane A, Nguyen B, Yao Y. Loss of mural cell-derived laminin aggravates hemorrhagic brain injury. J Neuroinflammation. 2020;17:103 pubmed 出版商
Galvani E, Mundra P, Valpione S, García Martínez P, Smith M, Greenall J, et al. Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma. Nat Commun. 2020;11:853 pubmed 出版商
Fang D, Tang Q, Kong Y, Wang Q, Gu J, Fang X, et al. MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment. J Immunother Cancer. 2019;7:327 pubmed 出版商
Tong D, Zhang L, Ning F, Xu Y, Hu X, Shi Y. Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival. Protein Cell. 2020;11:108-123 pubmed 出版商
Fang Y, Zhu L, An N, Jiang G, Qian J, Zhao R, et al. Blood autophagy defect causes accelerated non-hematopoietic organ aging. Aging (Albany NY). 2019;11:4910-4922 pubmed 出版商
Pascual García M, Bonfill Teixidor E, Planas Rigol E, Rubio Perez C, Iurlaro R, Arias A, et al. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy. Nat Commun. 2019;10:2416 pubmed 出版商
Chen L, Gu J, Qian Y, Li M, Qian Y, Xu M, et al. Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity. Cell Mol Gastroenterol Hepatol. 2019;7:623-639 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD3 Monoclonal Antibody (17A2), Functional Grade, eBioscience
目录# :
16-0032-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent
物种 :
小鼠
克隆 :
17A2
抗体亚型 :
IgG2b, kappa
储存 :
4° C
描述 :
The CD3 subunit complex which is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. The genes encoding the CD3 epsilon, gamma and delta polypeptides are located on chromosome 11. Defects in the CD3 gene are associated with CD3 immunodeficiency.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent
别名 :
4930549J05Rik; A430104F18Rik; AI504783; antigen CD3D, delta polypeptide (TiT3 complex); antigen CD3E, epsilon polypeptide (TiT3 complex); antigen CD3G, gamma polypeptide; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; CD3; CD3 antigen delta chain; CD3 antigen delta polypeptide; CD3 antigen gamma chain; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 antigen, epsilon polypeptide; CD3 antigen, gamma polypeptide; CD3 antigen, zeta polypeptide; CD3 delta; CD3 epsilon; CD3 epsilon chain; CD3 epsilon subunit; CD3 epsilon subunit precursor; CD3 gamma-chain; CD3 glycoprotein; CD3 glycoprotein precursor; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3 molecule, epsilon; CD3 molecule, epsilon polypeptide; CD3 molecule, gamma; CD3 molecule, gamma polypeptide; CD3 protein; CD3 TCR complex; CD3 type I transmembrane glycoprotein; CD3 type I transmembrane glycoprotein precursor; CD3 zeta chain; Cd3d; CD3D antigen delta; CD3D antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; Cd3e; CD3E antigen, epsilon polypeptide; CD3E antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3epsilon; CD3-epsilon; Cd3-eta; Cd3g; CD3G antigen, gamma polypeptide; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; Cd3h; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; Ctg3; Ctg-3; FLJ18683; IMD17; IMD18; IMD19; IMD25; Leu-4; OKT3, delta chain; T cell antigen receptor complex epsilon subunit of T3; T3/TCR complex; T3d; T3e; T3g; T3Z; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 epsilon chain; T-cell receptor CD3 epsilon subunit; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 delta chain; T-cell receptor T3 eta chain; T-cell receptor T3 gamma chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain; T-cell surface glycoprotein CD3 zeta chain; T-cell surface protein; TcR CD3 delta-chain; TcR CD3 gamma-chain; TCR zeta chain; TCR zeta chain subunit; TCRE; Tcrk; TCRZ; TCRzeta; TiT3 complex; type I transmembrane protein; T-cell surface molecule CD3
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公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国