产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD80 (B7-1) Monoclonal Antibody (2D10.4), Functional Grade, eBioscience
目录 :
16-0809-85
规格 :
500微克
价格 :
美国393
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2D10.4
反应物种 :
人类, 小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 17
出版应用/物种/样本/稀释 | 参考文献 |
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Bashuda H, Kimikawa M, Seino K, Kato Y, Ono F, Shimizu A, et al. Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates. J Clin Invest. 2005;115:1896-902 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD80 (B7-1) Monoclonal Antibody (2D10.4), Functional Grade, eBioscience
目录# :
16-0809-85
规格 :
500微克
定价 :
美国393
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent
物种 :
人类
克隆 :
2D10.4
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent
别名 :
Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1
更多信息或购买 :
公司信息
赛默飞世尔
产品浏览
- CD81 Monoclonal Antibody (Eat-2 (EAT2)), Functional Grade, eBioscience
- CD86 (B7-2) Monoclonal Antibody (PO3.1), Functional Grade, eBioscience
- CD86 (B7-2) Monoclonal Antibody (PO3.1), Functional Grade, eBioscience
- CD86 (B7-2) Monoclonal Antibody (IT2.2), Functional Grade, eBioscience
- CD90 (Thy-1) Monoclonal Antibody (G7), Functional Grade, eBioscience | 16-0901-85
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