产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD115 (c-fms) Monoclonal Antibody (AFS98), Functional Grade, eBioscience
目录 :
16-1152-38
规格 :
5毫克
价格 :
美国2750
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
AFS98
反应物种 :
小鼠
应用 :
中和反应, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 6d
Droho S, Cuda C, Perlman H, Lavine J. Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis. Sci Rep. 2021;11:18084 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s9c
Chu C, Murdock M, Jing D, Won T, Chung H, Kressel A, et al. The microbiota regulate neuronal function and fear extinction learning. Nature. 2019;574:543-548 pubmed 出版商
Yan Q, Gao H, Yao Q, Ling K, Xiao G. Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling. J Biol Chem. 2022;298:101639 pubmed 出版商
Oladiran O, Shi X, Fournier S, Zhang J. CX3CR1 But Not CCR2 Expression Is Required for the Development of Autoimmune Peripheral Neuropathy in Mice. Front Immunol. 2021;12:720733 pubmed 出版商
Fu J, Shih L, Yen T. HOXA11 plays critical roles in disease progression and response to cytarabine in AML. Oncol Rep. 2021;46: pubmed 出版商
Serrano López J, Hegde S, Kumar S, Serrano J, Fang J, Wellendorf A, et al. Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics. elife. 2021;10: pubmed 出版商
Oladiran O, Shi X, Yang M, Fournier S, Zhang J. Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy. J Neuroinflammation. 2021;18:77 pubmed 出版商
Wieghofer P, Hagemeyer N, Sankowski R, Schlecht A, Staszewski O, Amann L, et al. Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling. EMBO J. 2021;40:e105123 pubmed 出版商
Christofi M, Le Sommer S, Molzer C, Klaska I, Kuffova L, Forrester J. Low-dose 2-deoxy glucose stabilises tolerogenic dendritic cells and generates potent in vivo immunosuppressive effects. Cell Mol Life Sci. 2021;78:2857-2876 pubmed 出版商
Consiglio C, Gollnick S. Androgen Receptor Signaling Positively Regulates Monocytic Development. Front Immunol. 2020;11:519383 pubmed 出版商
Einw xe4 chter H, Heiseke A, Schlitzer A, Gasteiger G, Adler H, Voehringer D, et al. The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment. Front Immunol. 2020;11:1627 pubmed 出版商
Xiao J, Wang C, Yao J, Alippe Y, Yang T, Kress D, et al. Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells. PLoS Biol. 2020;18:e3000807 pubmed 出版商
Boeck M, Thien A, Wolf J, Hagemeyer N, Laich Y, Yusuf D, et al. Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model. Glia. 2020;68:1859-1873 pubmed 出版商
Wu M, Liu J, Li F, Huang S, He J, Xue Y, et al. Antibiotic-induced dysbiosis of gut microbiota impairs corneal development in postnatal mice by affecting CCR2 negative macrophage distribution. Mucosal Immunol. 2020;13:47-63 pubmed 出版商
Tong Y, Zhou L, Yang L, Guo P, Cao Y, Qin F, et al. Concomitant type I IFN and M-CSF signaling reprograms monocyte differentiation and drives pro-tumoral arginase production. EBioMedicine. 2019;39:132-144 pubmed 出版商
Liu J, Wu M, He J, Xiao C, Xue Y, Fu T, et al. Antibiotic-Induced Dysbiosis of Gut Microbiota Impairs Corneal Nerve Regeneration by Affecting CCR2-Negative Macrophage Distribution. Am J Pathol. 2018;188:2786-2799 pubmed 出版商
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Petvises S, Periasamy P, O Neill H. MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis. BMC Immunol. 2018;19:21 pubmed 出版商
Tang J, Frey J, Wilson C, Moncada Pazos A, Levet C, Freeman M, et al. Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation. Mol Cell Biol. 2018;38: pubmed 出版商
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Liu L, Yang L, Yan W, Zhai J, Pizzo D, Chu P, et al. Chemotherapy Induces Breast Cancer Stemness in Association with Dysregulated Monocytosis. Clin Cancer Res. 2018;24:2370-2382 pubmed 出版商
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Shen L, Yang Y, Ou T, Key C, Tong S, Sequeira R, et al. Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy. J Lipid Res. 2017;58:1808-1821 pubmed 出版商
Liron T, Raphael B, Hiram Bab S, Bab I, Gabet Y. Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes. J Cell Physiol. 2018;233:371-377 pubmed 出版商
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Wang T, Wang Z, Yang P, Xia L, Zhou M, Wang S, et al. PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice. Cell Death Dis. 2016;7:e2176 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD115 (c-fms) Monoclonal Antibody (AFS98), Functional Grade, eBioscience
目录# :
16-1152-38
规格 :
5毫克
价格 :
美国2750
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 1 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
物种 :
小鼠
克隆 :
AFS98
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
CSF1R (colony stimulating factor 1 receptor) is a cytokine that controls the production, differentiation, and function of macrophages. CSF1R mediates most if not all of the biological effects of CSF1. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. CSF1R is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and plays an important role in innate immunity and in inflammatory processes. The first intron of the CSF1R gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Mutations in the CSF1R gene have been associated with a predisposition to myeloid malignancy.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
别名 :
AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; CSFIR; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; FMS; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; protein-tyrosine kinase; proto-oncogene c-Fms; proto-oncogene fms
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国