产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD127 Monoclonal Antibody (A7R34), Functional Grade, eBioscience
目录 :
16-1271-85
规格 :
500微克
价格 :
美国395
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
A7R34
反应物种 :
人类, 小鼠
应用 :
免疫组化, 中和反应, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 342
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 s1f
Gopal A, Ibrahim R, Fuller M, Umlandt P, Parker J, Tran J, et al. TIRAP drives myelosuppression through an Ifnγ-Hmgb1 axis that disrupts the endothelial niche in mice. J Exp Med. 2022;219: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200
Amoozgar Z, Kloepper J, Ren J, Tay R, Kazer S, Kiner E, et al. Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas. Nat Commun. 2021;12:2582 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Bai L, Lyu Y, Shi G, Li K, Huang Y, Ma Y, et al. Polymerase I and transcript release factor transgenic mice show impaired function of hematopoietic stem cells. Aging (Albany NY). 2020;12:20152-20162 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
Steer C, Mathä L, Shim H, Takei F. Lung group 2 innate lymphoid cells are trained by endogenous IL-33 in the neonatal period. JCI Insight. 2020;5: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Takagaki S, Yamashita R, Hashimoto N, Sugihara K, Kanari K, Tabata K, et al. Galactosyl carbohydrate residues on hematopoietic stem/progenitor cells are essential for homing and engraftment to the bone marrow. Sci Rep. 2019;9:7133 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6a
Visekruna A, Hartmann S, Sillke Y, Glauben R, Fischer F, Raifer H, et al. Intestinal development and homeostasis require activation and apoptosis of diet-reactive T cells. J Clin Invest. 2019;129:1972-1983 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2b
Qian L, Bajana S, Georgescu C, Peng V, Wang H, Adrianto I, et al. Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors. J Exp Med. 2019;216:884-899 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:25; 图 1a
Melo Gonzalez F, Kammoun H, Evren E, Dutton E, Papadopoulou M, Bradford B, et al. Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria. J Exp Med. 2019;216:728-742 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 3d
Olesen M, Christiansen J, Petersen S, Jensen P, Paslawski W, Romero Ramos M, et al. CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology. Heliyon. 2018;4:e00513 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3f
Yang J, Cornelissen F, Papazian N, Reijmers R, Llorian M, Cupedo T, et al. IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes. J Exp Med. 2018;215:1069-1077 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Omilusik K, Nadjsombati M, Shaw L, Yu B, Milner J, Goldrath A. Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8+ T cells. J Exp Med. 2018;215:773-783 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s6a
Huang Y, Mao K, Chen X, Sun M, Kawabe T, Li W, et al. S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense. Science. 2018;359:114-119 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1e
Harly C, Cam M, Kaye J, Bhandoola A. Development and differentiation of early innate lymphoid progenitors. J Exp Med. 2018;215:249-262 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s6b
Danahy D, Anthony S, Jensen I, Hartwig S, Shan Q, Xue H, et al. Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells. PLoS Pathog. 2017;13:e1006569 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Bruce D, Stefanski H, Vincent B, Dant T, Reisdorf S, Bommiasamy H, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. J Clin Invest. 2017;127:1813-1825 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 1a
Katerndahl C, Heltemes Harris L, Willette M, Henzler C, Frietze S, Yang R, et al. Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival. Nat Immunol. 2017;18:694-704 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Szabo P, Goswami A, Mazzuca D, Kim K, O Gorman D, Hess D, et al. Rapid and Rigorous IL-17A Production by a Distinct Subpopulation of Effector Memory T Lymphocytes Constitutes a Novel Mechanism of Toxic Shock Syndrome Immunopathology. J Immunol. 2017;198:2805-2818 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Nish S, Zens K, Kratchmarov R, Lin W, Adams W, Chen Y, et al. CD4+ T cell effector commitment coupled to self-renewal by asymmetric cell divisions. J Exp Med. 2017;214:39-47 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Ladle B, Li K, Phillips M, Pucsek A, Haile A, Powell J, et al. De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation. Proc Natl Acad Sci U S A. 2016;113:10631-6 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Chen S, Miyazaki M, Chandra V, Fisch K, Chang A, Murre C. Id3 Orchestrates Germinal Center B Cell Development. Mol Cell Biol. 2016;36:2543-52 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2c
Wang S, Xia P, Chen Y, Huang G, Xiong Z, Liu J, et al. Natural Killer-like B Cells Prime Innate Lymphocytes against Microbial Infection. Immunity. 2016;45:131-44 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Terashima A, Okamoto K, Nakashima T, Akira S, Ikuta K, Takayanagi H. Sepsis-Induced Osteoblast Ablation Causes Immunodeficiency. Immunity. 2016;44:1434-43 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Saha A, O Connor R, Thangavelu G, Lovitch S, Dandamudi D, Wilson C, et al. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. J Clin Invest. 2016;126:2642-60 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 s3
Li Z, Hodgkinson T, Gothard E, Boroumand S, Lamb R, Cummins I, et al. Epidermal Notch1 recruits RORγ(+) group 3 innate lymphoid cells to orchestrate normal skin repair. Nat Commun. 2016;7:11394 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s18a, s2b
Gomez de Agüero M, Ganal Vonarburg S, Fuhrer T, Rupp S, Uchimura Y, Li H, et al. The maternal microbiota drives early postnatal innate immune development. Science. 2016;351:1296-302 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Tagliamonte M, Petrizzo A, Napolitano M, Luciano A, Rea D, Barbieri A, et al. A novel multi-drug metronomic chemotherapy significantly delays tumor growth in mice. J Transl Med. 2016;14:58 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3e
Lu K, Nakagawa M, Thummar K, RATHINAM C. Slicer Endonuclease Argonaute 2 Is a Negative Regulator of Hematopoietic Stem Cell Quiescence. Stem Cells. 2016;34:1343-53 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1, 2
Kim J, Choi Y, Lee B, Song M, Ban C, Kim J, et al. Programmed cell death ligand 1 alleviates psoriatic inflammation by suppressing IL-17A production from programmed cell death 1-high T cells. J Allergy Clin Immunol. 2016;137:1466-1476.e3 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Moretto M, Khan I. IL-21 Is Important for Induction of KLRG1+ Effector CD8 T Cells during Acute Intracellular Infection. J Immunol. 2016;196:375-84 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Verma S, Weiskopf D, Gupta A, McDonald B, Peters B, Sette A, et al. Cytomegalovirus-Specific CD4 T Cells Are Cytolytic and Mediate Vaccine Protection. J Virol. 2016;90:650-8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Aparicio Domingo P, Romera Hernandez M, Karrich J, Cornelissen F, Papazian N, Lindenbergh Kortleve D, et al. Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage. J Exp Med. 2015;212:1783-91 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Guo L, Huang Y, Chen X, Hu Li J, Urban J, Paul W. Innate immunological function of TH2 cells in vivo. Nat Immunol. 2015;16:1051-9 pubmed 出版商
  • 流式细胞仪; 小鼠
Xin L, Jiang T, Kinder J, Ertelt J, Way S. Infection susceptibility and immune senescence with advancing age replicated in accelerated aging Lmna(Dhe) mice. Aging Cell. 2015;14:1122-6 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Arbelaez C, Glatigny S, Duhen R, Eberl G, Oukka M, Bettelli E. IL-7/IL-7 Receptor Signaling Differentially Affects Effector CD4+ T Cell Subsets Involved in Experimental Autoimmune Encephalomyelitis. J Immunol. 2015;195:1974-83 pubmed 出版商
  • 流式细胞仪; 小鼠
Vuillefroy de Silly R, Ducimetière L, Yacoub Maroun C, Dietrich P, Derouazi M, Walker P. Phenotypic switch of CD8(+) T cells reactivated under hypoxia toward IL-10 secreting, poorly proliferative effector cells. Eur J Immunol. 2015;45:2263-75 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Moguche A, Shafiani S, Clemons C, Larson R, Dinh C, Higdon L, et al. ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis. J Exp Med. 2015;212:715-28 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Rao T, Marks Bluth J, Sullivan J, Gupta M, Chandrakanthan V, Fitch S, et al. High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice. Stem Cell Res. 2015;14:307-22 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Charlton J, Tsoukatou D, Mamalaki C, Chatzidakis I. Programmed death 1 regulates memory phenotype CD4 T cell accumulation, inhibits expansion of the effector memory phenotype subset and modulates production of effector cytokines. PLoS ONE. 2015;10:e0119200 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Wensveen F, Jelenčić V, Valentić S, Å estan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Hu W, Dooley J, Chung S, Chandramohan D, Cimmino L, Mukherjee S, et al. miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 2015;125:2206-16 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Hannani D, Vétizou M, Enot D, Rusakiewicz S, Chaput N, Klatzmann D, et al. Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25. Cell Res. 2015;25:208-24 pubmed 出版商
  • 流式细胞仪; 小鼠
Yuan X, Dee M, Altman N, Malek T. IL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa. J Immunol. 2015;194:1334-46 pubmed 出版商
  • 流式细胞仪; 小鼠
Karamitros D, Patmanidi A, Kotantaki P, Potocnik A, Bähr Ivacevic T, Benes V, et al. Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors. Development. 2015;142:70-81 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Nakamura M, Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, et al. A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice. J Immunol. 2015;194:243-51 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Fahl S, Harris B, Coffey F, Wiest D. Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint. J Immunol. 2015;194:200-9 pubmed
  • 流式细胞仪; 小鼠; 图 1a
Backer R, Helbig C, Gentek R, Kent A, Laidlaw B, Dominguez C, et al. A central role for Notch in effector CD8(+) T cell differentiation. Nat Immunol. 2014;15:1143-51 pubmed 出版商
  • 流式细胞仪; 小鼠
Penaloza MacMaster P, Kamphorst A, Wieland A, Araki K, Iyer S, West E, et al. Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection. J Exp Med. 2014;211:1905-18 pubmed 出版商
  • 流式细胞仪; 小鼠
Denton A, Roberts E, Linterman M, Fearon D. Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells. Proc Natl Acad Sci U S A. 2014;111:12139-44 pubmed 出版商
  • 流式细胞仪; 小鼠
Lee J, Walsh M, Hoehn K, James D, Wherry E, Choi Y. Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity. J Immunol. 2014;192:3190-9 pubmed 出版商
  • 流式细胞仪; 小鼠; 表 1
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Nussbaum J, Van Dyken S, von Moltke J, Cheng L, Mohapatra A, Molofsky A, et al. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature. 2013;502:245-8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Wu X, Satpathy A, Kc W, Liu P, Murphy T, Murphy K. Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo. PLoS ONE. 2013;8:e64800 pubmed 出版商
  • 流式细胞仪; 小鼠
Powell N, Walker A, Stolarczyk E, Canavan J, Gökmen M, Marks E, et al. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity. 2012;37:674-84 pubmed 出版商
  • 流式细胞仪; 小鼠
Randall K, Chan S, Ma C, Fung I, Mei Y, Yabas M, et al. DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice. J Exp Med. 2011;208:2305-20 pubmed 出版商
  • 免疫组化; 小鼠; 图 4
Ota N, Wong K, Valdez P, Zheng Y, Crellin N, Diehl L, et al. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nat Immunol. 2011;12:941-8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Fahl S, Crittenden R, Allman D, Bender T. c-Myb is required for pro-B cell differentiation. J Immunol. 2009;183:5582-92 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Kastenmuller W, Gasteiger G, Stross L, Busch D, Drexler I. Cutting edge: mucosal application of a lyophilized viral vector vaccine confers systemic and protective immunity toward intracellular pathogens. J Immunol. 2009;182:2573-7 pubmed 出版商
  • 流式细胞仪; 小鼠
Maillard I, Chen Y, Friedman A, Yang Y, Tubbs A, Shestova O, et al. Menin regulates the function of hematopoietic stem cells and lymphoid progenitors. Blood. 2009;113:1661-9 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Cooper M, Elliott J, Keyel P, Yang L, Carrero J, Yokoyama W. Cytokine-induced memory-like natural killer cells. Proc Natl Acad Sci U S A. 2009;106:1915-9 pubmed 出版商
  • 流式细胞仪; 小鼠
Rana S, Byrne S, MacDonald L, Chan C, Halliday G. Ultraviolet B suppresses immunity by inhibiting effector and memory T cells. Am J Pathol. 2008;172:993-1004 pubmed 出版商
  • 流式细胞仪; 小鼠
Sridhar S, Reyes Sandoval A, Draper S, Moore A, Gilbert S, Gao G, et al. Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A. J Virol. 2008;82:3822-33 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Ahonen C, Wasiuk A, Fuse S, Turk M, Ernstoff M, Suriawinata A, et al. Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines. Blood. 2008;111:3116-25 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Stemberger C, Huster K, Koffler M, Anderl F, Schiemann M, Wagner H, et al. A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets. Immunity. 2007;27:985-97 pubmed
  • 流式细胞仪; 小鼠
Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood. 2008;111:142-9 pubmed
  • 流式细胞仪; 小鼠; 图 2
Badovinac V, Harty J. Manipulating the rate of memory CD8+ T cell generation after acute infection. J Immunol. 2007;179:53-63 pubmed
  • 流式细胞仪; 小鼠; 图 4
Huster K, Koffler M, Stemberger C, Schiemann M, Wagner H, Busch D. Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells. Eur J Immunol. 2006;36:1453-64 pubmed
  • 流式细胞仪; 小鼠; 图 2
Yang T, Millar J, Groves T, Grinshtein N, Parsons R, Takenaka S, et al. The CD8+ T cell population elicited by recombinant adenovirus displays a novel partially exhausted phenotype associated with prolonged antigen presentation that nonetheless provides long-term immunity. J Immunol. 2006;176:200-10 pubmed
  • 流式细胞仪; 小鼠
Lacombe M, Hardy M, Rooney J, Labrecque N. IL-7 receptor expression levels do not identify CD8+ memory T lymphocyte precursors following peptide immunization. J Immunol. 2005;175:4400-7 pubmed
  • 流式细胞仪; 小鼠
Irwin S, Izzo A, Dow S, Skeiky Y, Reed S, Alderson M, et al. Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein. Infect Immun. 2005;73:5809-16 pubmed
Cannons J, Villarino A, Kapnick S, Preite S, Shih H, Gomez Rodriguez J, et al. PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory. Cell Rep. 2021;37:109804 pubmed 出版商
Yun J, Lee C, Liu T, Liu S, Kim E, Xu S, et al. Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice. JCI Insight. 2021;6: pubmed 出版商
Rana A, de Almeida F, Paico Montero H, Gonzales Carazas M, Bortoluci K, Sad S, et al. RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes. Front Immunol. 2020;11:536 pubmed 出版商
Magen A, Nie J, Ciucci T, Tamoutounour S, Zhao Y, Mehta M, et al. Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells. Cell Rep. 2019;29:3019-3032.e6 pubmed 出版商
Xu W, Cherrier D, Chea S, Vosshenrich C, Serafini N, Petit M, et al. An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials. Immunity. 2019;50:1054-1068.e3 pubmed 出版商
Twohig J, Cardus Figueras A, Andrews R, Wiede F, Cossins B, Derrac Soria A, et al. Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nat Immunol. 2019;20:458-470 pubmed 出版商
Zhang Z, Huang Z, Ong B, Sahu C, Zeng H, Ruan H. Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis. Haematologica. 2019;: pubmed 出版商
Szappanos D, Tschismarov R, Perlot T, Westermayer S, Fischer K, Platanitis E, et al. The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity. PLoS Pathog. 2018;14:e1007397 pubmed 出版商
Zhang W, Li Q, Li D, Li J, Aki D, Liu Y. The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation. J Exp Med. 2018;215:3180-3193 pubmed 出版商
Rao T, Gupta M, Softic S, Wang L, Jang Y, Thomou T, et al. Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors. EMBO J. 2018;37: pubmed 出版商
Grigoryan A, Guidi N, Senger K, Liehr T, Soller K, Marka G, et al. LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells. Genome Biol. 2018;19:189 pubmed 出版商
Cardinez C, Miraghazadeh B, Tanita K, Da Silva E, Hoshino A, Okada S, et al. Gain-of-function IKBKB mutation causes human combined immune deficiency. J Exp Med. 2018;215:2715-2724 pubmed 出版商
Badamchi Zadeh A, Moynihan K, Larocca R, Aid M, Provine N, Iampietro M, et al. Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy. J Immunol. 2018;201:2744-2752 pubmed 出版商
Dickinson G, Levenson E, Walker J, Kearney J, Alugupalli K. IL-7 Enables Antibody Responses to Bacterial Polysaccharides by Promoting B Cell Receptor Diversity. J Immunol. 2018;201:1229-1240 pubmed 出版商
Rogers M, Lamens K, Shafagati N, Johnson M, Oury T, Joyce S, et al. CD4+ Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses. J Immunol. 2018;201:1253-1266 pubmed 出版商
Tejero J, Armand N, Finn C, Dhume K, Strutt T, Chai K, et al. Cigarette smoke extract acts directly on CD4 T cells to enhance Th1 polarization and reduce memory potential. Cell Immunol. 2018;331:121-129 pubmed 出版商
Lam J, van den Bosch M, Wegrzyn J, Parker J, Ibrahim R, Slowski K, et al. miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling. Nat Commun. 2018;9:2418 pubmed 出版商
Kirkling M, Cytlak U, Lau C, Lewis K, Resteu A, Khodadadi Jamayran A, et al. Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells. Cell Rep. 2018;23:3658-3672.e6 pubmed 出版商
Liu T, Kong W, Tang X, Xu M, Wang Q, Zhang B, et al. The transcription factor Zfp90 regulates the self-renewal and differentiation of hematopoietic stem cells. Cell Death Dis. 2018;9:677 pubmed 出版商
Drobek A, Moudra A, Mueller D, Huranová M, Horková V, Pribikova M, et al. Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells. EMBO J. 2018;37: pubmed 出版商
Rothberg J, Maganti H, Jrade H, Porter C, Palidwor G, Cafariello C, et al. Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis. Cell Discov. 2018;4:21 pubmed 出版商
Baba O, Horie T, Nakao T, Hakuno D, Nakashima Y, Nishi H, et al. MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways. Mol Cell Biol. 2018;38: pubmed 出版商
Sumida H, Cyster J. G-Protein Coupled Receptor 18 Contributes to Establishment of the CD8 Effector T Cell Compartment. Front Immunol. 2018;9:660 pubmed 出版商
Jiang L, Han X, Wang J, Wang C, Sun X, Xie J, et al. SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling. J Exp Med. 2018;215:1337-1347 pubmed 出版商
Khong H, Volmari A, Sharma M, Dai Z, Imo C, Hailemichael Y, et al. Peptide Vaccine Formulation Controls the Duration of Antigen Presentation and Magnitude of Tumor-Specific CD8+ T Cell Response. J Immunol. 2018;200:3464-3474 pubmed 出版商
Xia P, Wang S, Ye B, Du Y, Li C, Xiong Z, et al. A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion. Immunity. 2018;48:688-701.e7 pubmed 出版商
Sun C, Lan P, Han Q, Huang M, Zhang Z, Xu G, et al. Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion. Nat Commun. 2018;9:1241 pubmed 出版商
Seike M, Omatsu Y, Watanabe H, Kondoh G, Nagasawa T. Stem cell niche-specific Ebf3 maintains the bone marrow cavity. Genes Dev. 2018;32:359-372 pubmed 出版商
Blass E, Aid M, Martinot A, Larocca R, Kang Z, Badamchi Zadeh A, et al. Adenovirus Vector Vaccination Impacts NK Cell Rheostat Function following Lymphocytic Choriomeningitis Virus Infection. J Virol. 2018;92: pubmed 出版商
Tinoco R, Carrette F, Henriquez M, Fujita Y, Bradley L. Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4+ T Cells. J Immunol. 2018;200:2690-2702 pubmed 出版商
Khan A, Carpenter B, Santos e Sousa P, Pospori C, Khorshed R, Griffin J, et al. Redirection to the bone marrow improves T cell persistence and antitumor functions. J Clin Invest. 2018;128:2010-2024 pubmed 出版商
Lauron E, Yang L, Elliott J, Gainey M, Fremont D, Yokoyama W. Cross-priming induces immunodomination in the presence of viral MHC class I inhibition. PLoS Pathog. 2018;14:e1006883 pubmed 出版商
Luo B, Chen K, Feng Q, Xiao W, Ma D, Yang H, et al. The interplay of BMP4 and IL?7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia?reperfusion. Int J Mol Med. 2018;41:2640-2650 pubmed 出版商
Lu Z, Hong C, Kong G, Assumpção A, Ong I, Bresnick E, et al. Polycomb Group Protein YY1 Is an Essential Regulator of Hematopoietic Stem Cell Quiescence. Cell Rep. 2018;22:1545-1559 pubmed 出版商
Tenno M, Kojo S, Lawir D, Hess I, Shiroguchi K, Ebihara T, et al. Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors. J Exp Med. 2018;215:595-610 pubmed 出版商
Kostrzewski T, Borg A, Meng Y, Filipovic I, Male V, Wack A, et al. Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development. J Immunol. 2018;200:1370-1381 pubmed 出版商
Ibitokou S, Dillon B, Sinha M, Szczesny B, Delgadillo A, Reda Abdelrahman D, et al. Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection. J Immunol. 2018;200:643-656 pubmed 出版商
Milner J, Toma C, Yu B, Zhang K, Omilusik K, Phan A, et al. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. 2017;552:253-257 pubmed 出版商
Wang Y, Xiao M, Tao C, Chen J, Wang Z, Yang J, et al. Inactivation of mTORC1 Signaling in Osterix-expressing Cells Impairs B-cell Differentiation. J Bone Miner Res. 2017;: pubmed 出版商
Bartemes K, Chen C, Iijima K, Drake L, Kita H. IL-33-Responsive Group 2 Innate Lymphoid Cells Are Regulated by Female Sex Hormones in the Uterus. J Immunol. 2018;200:229-236 pubmed 出版商
Wasiuk A, Testa J, Weidlick J, Sisson C, Vitale L, Widger J, et al. CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy. J Immunol. 2017;199:4110-4123 pubmed 出版商
Delpoux A, Lai C, Hedrick S, Doedens A. FOXO1 opposition of CD8+ T cell effector programming confers early memory properties and phenotypic diversity. Proc Natl Acad Sci U S A. 2017;114:E8865-E8874 pubmed 出版商
Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, et al. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32:377-391.e9 pubmed 出版商
Yasunaga M, Manabe S, Matsumura Y. Immunoregulation by IL-7R-targeting antibody-drug conjugates: overcoming steroid-resistance in cancer and autoimmune disease. Sci Rep. 2017;7:10735 pubmed 出版商
Pei W, Feyerabend T, Rössler J, Wang X, Postrach D, Busch K, et al. Polylox barcoding reveals haematopoietic stem cell fates realized in vivo. Nature. 2017;548:456-460 pubmed 出版商
He Z, Chen L, Souto F, Canasto Chibuque C, Bongers G, Deshpande M, et al. Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc Min/+ mice. Sci Rep. 2017;7:5520 pubmed 出版商
Trsan T, Vuković K, Filipović P, Brizić A, Lemmermann N, Schober K, et al. Cytomegalovirus vector expressing RAE-1? induces enhanced anti-tumor capacity of murine CD8+ T cells. Eur J Immunol. 2017;47:1354-1367 pubmed 出版商
Miosge L, Sontani Y, Chuah A, Horikawa K, Russell T, Mei Y, et al. Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion. Proc Natl Acad Sci U S A. 2017;114:E5216-E5225 pubmed 出版商
Xia P, Liu J, Wang S, Ye B, Du Y, Xiong Z, et al. WASH maintains NKp46+ ILC3 cells by promoting AHR expression. Nat Commun. 2017;8:15685 pubmed 出版商
Becattini S, Littmann E, Carter R, Kim S, Morjaria S, Ling L, et al. Commensal microbes provide first line defense against Listeria monocytogenes infection. J Exp Med. 2017;214:1973-1989 pubmed 出版商
Bergmann H, Roth S, Pechloff K, Kiss E, Kuhn S, Heikenwalder M, et al. Card9-dependent IL-1? regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer. Eur J Immunol. 2017;47:1342-1353 pubmed 出版商
Guidi N, Sacma M, Ständker L, Soller K, Marka G, Eiwen K, et al. Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells. EMBO J. 2017;36:840-853 pubmed 出版商
Rogel A, Willoughby J, Buchan S, Leonard H, Thirdborough S, Al Shamkhani A. Akt signaling is critical for memory CD8+ T-cell development and tumor immune surveillance. Proc Natl Acad Sci U S A. 2017;114:E1178-E1187 pubmed 出版商
Cañete A, Carmona R, Ariza L, Sanchez M, Rojas A, Muñoz Chápuli R. A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice. Haematologica. 2017;102:647-655 pubmed 出版商
Le Q, Yao W, Chen Y, Yan B, Liu C, Yuan M, et al. GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal. Cell Death Dis. 2016;7:e2478 pubmed 出版商
Ramirez Carrozzi V, Sambandam A, Zhou M, Yan D, Kang J, Wu X, et al. Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone. J Allergy Clin Immunol. 2017;139:705-708.e6 pubmed 出版商
Carow B, Gao Y, Coquet J, Reilly M, Rottenberg M. lck-Driven Cre Expression Alters T Cell Development in the Thymus and the Frequencies and Functions of Peripheral T Cell Subsets. J Immunol. 2016;197:2261-8 pubmed 出版商
Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed 出版商
Keil M, Sonner J, Lanz T, Oezen I, Bunse T, Bittner S, et al. General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation. J Neuroimmunol. 2016;297:117-26 pubmed 出版商
Reynaldi A, Smith N, Schlub T, Venturi V, Rudd B, Davenport M. Modeling the dynamics of neonatal CD8+ T-cell responses. Immunol Cell Biol. 2016;94:838-848 pubmed 出版商
Rabacal W, Pabbisetty S, Hoek K, Cendron D, Guo Y, Maseda D, et al. Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival. Proc Natl Acad Sci U S A. 2016;113:5370-5 pubmed 出版商
Pugh J, Foster S, Sukhina A, Petravic J, Uhrlaub J, Padilla Torres J, et al. Acute systemic DNA damage in youth does not impair immune defense with aging. Aging Cell. 2016;15:686-93 pubmed 出版商
Boulter N, Suarez F, Schibeci S, Sunderland T, Tolhurst O, Hunter T, et al. A simple, accurate and universal method for quantification of PCR. BMC Biotechnol. 2016;16:27 pubmed 出版商
Shen W, Hixon J, McLean M, Li W, Durum S. IL-22-Expressing Murine Lymphocytes Display Plasticity and Pathogenicity in Reporter Mice. Front Immunol. 2015;6:662 pubmed 出版商
Morabito K, Erez N, Graham B, Ruckwardt T. Phenotype and Hierarchy of Two Transgenic T Cell Lines Targeting the Respiratory Syncytial Virus KdM282-90 Epitope Is Transfer Dose-Dependent. PLoS ONE. 2016;11:e0146781 pubmed 出版商
Durward Diioia M, Harms J, Khan M, Hall C, Smith J, Splitter G. CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection. Infect Immun. 2015;83:4759-71 pubmed 出版商
Laidlaw B, Cui W, Amezquita R, Gray S, Guan T, Lu Y, et al. Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells. Nat Immunol. 2015;16:871-9 pubmed 出版商
Gaide O, Emerson R, Jiang X, Gulati N, Nizza S, Desmarais C, et al. Common clonal origin of central and resident memory T cells following skin immunization. Nat Med. 2015;21:647-53 pubmed 出版商
Pollizzi K, Patel C, Sun I, Oh M, Waickman A, Wen J, et al. mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation. J Clin Invest. 2015;125:2090-108 pubmed 出版商
Pascutti M, Geerman S, Slot E, van Gisbergen K, Boon L, Arens R, et al. Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection. PLoS Pathog. 2015;11:e1004675 pubmed 出版商
Miyazaki M, Miyazaki K, Chen S, Chandra V, Wagatsuma K, Agata Y, et al. The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis. Genes Dev. 2015;29:409-25 pubmed 出版商
Nakagawa M, Thummar K, Mandelbaum J, Pasqualucci L, RATHINAM C. Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence. J Exp Med. 2015;212:203-16 pubmed 出版商
Xu X, Araki K, Li S, Han J, Ye L, Tan W, et al. Autophagy is essential for effector CD8(+) T cell survival and memory formation. Nat Immunol. 2014;15:1152-61 pubmed 出版商
Lee C, Fulcher D, Whittle B, Chand R, Fewings N, Field M, et al. Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100. Blood. 2014;124:2964-72 pubmed 出版商
Xia P, Wang S, Huang G, Zhu P, Li M, Ye B, et al. WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner. J Exp Med. 2014;211:2119-34 pubmed 出版商
Boulet S, Daudelin J, Labrecque N. IL-2 induction of Blimp-1 is a key in vivo signal for CD8+ short-lived effector T cell differentiation. J Immunol. 2014;193:1847-54 pubmed 出版商
Sojka D, Plougastel Douglas B, Yang L, Pak Wittel M, Artyomov M, Ivanova Y, et al. Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells. elife. 2014;3:e01659 pubmed 出版商
Webster K, Kim H, Kyparissoudis K, Corpuz T, Pinget G, Uldrich A, et al. IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival. Mucosal Immunol. 2014;7:1058-67 pubmed 出版商
Cheng W, Wee K, Kollmann T, Dutz J. Topical CpG adjuvantation of a protein-based vaccine induces protective immunity to Listeria monocytogenes. Clin Vaccine Immunol. 2014;21:329-39 pubmed 出版商
Brinkhoff B, Ostroumov D, Heemcke J, Woller N, Gürlevik E, Manns M, et al. Microsphere priming facilitates induction of potent therapeutic T-cell immune responses against autochthonous liver cancers. Eur J Immunol. 2014;44:1213-24 pubmed 出版商
Mollo S, Zajac A, Harrington L. Temporal requirements for B cells in the establishment of CD4 T cell memory. J Immunol. 2013;191:6052-9 pubmed 出版商
Keating R, Hertz T, Wehenkel M, Harris T, Edwards B, McClaren J, et al. The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus. Nat Immunol. 2013;14:1266-76 pubmed 出版商
Takahara M, Nemoto Y, Oshima S, Matsuzawa Y, Kanai T, Okamoto R, et al. IL-7 promotes long-term in vitro survival of unique long-lived memory subset generated from mucosal effector memory CD4+ T cells in chronic colitis mice. Immunol Lett. 2013;156:82-93 pubmed 出版商
Maina V, Marrella V, Mantero S, Cassani B, Fontana E, Anselmo A, et al. Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration. J Leukoc Biol. 2013;94:1221-30 pubmed 出版商
Fulton R, Weiss K, Pewe L, Harty J, Varga S. Aged mice exhibit a severely diminished CD8 T cell response following respiratory syncytial virus infection. J Virol. 2013;87:12694-700 pubmed 出版商
Mielke L, Groom J, Rankin L, Seillet C, Masson F, Putoczki T, et al. TCF-1 controls ILC2 and NKp46+ROR?t+ innate lymphocyte differentiation and protection in intestinal inflammation. J Immunol. 2013;191:4383-91 pubmed 出版商
Prabhu N, Ho A, Wong K, Hutchinson P, Chua Y, Kandasamy M, et al. Gamma interferon regulates contraction of the influenza virus-specific CD8 T cell response and limits the size of the memory population. J Virol. 2013;87:12510-22 pubmed 出版商
Schjerven H, McLaughlin J, Arenzana T, Frietze S, Cheng D, Wadsworth S, et al. Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros. Nat Immunol. 2013;14:1073-83 pubmed 出版商
Rowe A, Murray S, Raué H, Koguchi Y, Slifka M, Parker D. A cell-intrinsic requirement for NF-?B-inducing kinase in CD4 and CD8 T cell memory. J Immunol. 2013;191:3663-72 pubmed 出版商
Cooney L, Gupta M, Thomas S, Mikolajczak S, Choi K, Gibson C, et al. Short-lived effector CD8 T cells induced by genetically attenuated malaria parasite vaccination express CD11c. Infect Immun. 2013;81:4171-81 pubmed 出版商
Beus J, Hashmi S, Selvaraj S, Duan D, Stempora L, Monday S, et al. Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection. PLoS ONE. 2013;8:e71221 pubmed 出版商
Li G, Yang Q, Zhu Y, Wang H, Chen X, Zhang X, et al. T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells. PLoS ONE. 2013;8:e67401 pubmed 出版商
Bhadra R, Cobb D, Khan I. Donor CD8+ T cells prevent Toxoplasma gondii de-encystation but fail to rescue the exhausted endogenous CD8+ T cell population. Infect Immun. 2013;81:3414-25 pubmed 出版商
Miyazaki Y, Tsumiyama K, Yamane T, Ito M, Shiozawa S. Expansion of PD-1-positive effector CD4 T cells in an experimental model of SLE: contribution to the self-organized criticality theory. Kobe J Med Sci. 2013;59:E64-71 pubmed
Shitara S, Hara T, Liang B, Wagatsuma K, Zuklys S, Hollander G, et al. IL-7 produced by thymic epithelial cells plays a major role in the development of thymocytes and TCR??+ intraepithelial lymphocytes. J Immunol. 2013;190:6173-9 pubmed 出版商
Hamanaka S, Ooehara J, Morita Y, Ema H, Takahashi S, Miyawaki A, et al. Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method. Biochem Biophys Res Commun. 2013;435:586-91 pubmed 出版商
Nemoto Y, Kanai T, Takahara M, Oshima S, Okamoto R, Tsuchiya K, et al. Th1/Th17-mediated interstitial pneumonia in chronic colitis mice independent of intestinal microbiota. J Immunol. 2013;190:6616-25 pubmed 出版商
Masson F, Minnich M, Olshansky M, Bilic I, Mount A, Kallies A, et al. Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation. J Immunol. 2013;190:4585-94 pubmed 出版商
Pongratz G, Anthofer J, Melzer M, Anders S, Grassel S, Straub R. IL-7 receptor ? expressing B cells act proinflammatory in collagen-induced arthritis and are inhibited by sympathetic neurotransmitters. Ann Rheum Dis. 2014;73:306-12 pubmed 出版商
Daudelin J, Mathieu M, Boulet S, Labrecque N. IL-6 production by dendritic cells is dispensable for CD8+ memory T-cell generation. Biomed Res Int. 2013;2013:126189 pubmed 出版商
Jessen B, Bode S, Ammann S, Chakravorty S, Davies G, Diestelhorst J, et al. The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2. Blood. 2013;121:2943-51 pubmed 出版商
Jiang J, Champion C, Wei B, Liu G, Kelly K. CD8?CXCR5? T cells regulate pathology in the genital tract. Infect Dis Obstet Gynecol. 2013;2013:813238 pubmed 出版商
Yamamoto M, Seki Y, Iwai K, Ko I, Martin A, Tsuji N, et al. Ontogeny and localization of the cells produce IL-2 in healthy animals. Cytokine. 2013;61:831-41 pubmed 出版商
Jeannet R, Cai Q, Liu H, Vu H, Kuo Y. Alcam regulates long-term hematopoietic stem cell engraftment and self-renewal. Stem Cells. 2013;31:560-71 pubmed 出版商
Franke K, Kalucka J, Mamlouk S, Singh R, Muschter A, Weidemann A, et al. HIF-1? is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2?-induced excessive erythropoiesis. Blood. 2013;121:1436-45 pubmed 出版商
Hackstein H, Wachtendorf A, Kranz S, Lohmeyer J, Bein G, Baal N. Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains. Respir Res. 2012;13:94 pubmed 出版商
Sato T, Chiba T, Ohno S, Sato C, Sugoh T, Miyashita K, et al. Reciprocal control of G1-phase progression is required for Th-POK/Runx3-mediated CD4/8 thymocyte cell fate decision. J Immunol. 2012;189:4426-36 pubmed 出版商
Krishnamoorthy N, Khare A, Oriss T, Raundhal M, Morse C, Yarlagadda M, et al. Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma. Nat Med. 2012;18:1525-30 pubmed 出版商
Baru A, Untucht C, Ganesh V, Hesse C, Mayer C, Sparwasser T. Optimal isolation of functional Foxp3+ induced regulatory T cells using DEREG mice. PLoS ONE. 2012;7:e44760 pubmed 出版商
Van Belle T, Ling E, Haase C, Bresson D, Ursø B, Von Herrath M. NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes. J Autoimmun. 2013;40:66-73 pubmed 出版商
Guo X, Jie Y, Ren D, Zeng H, Zhang Y, He Y, et al. In vitro-expanded CD4(+)CD25(high)Foxp3(+) regulatory T cells controls corneal allograft rejection. Hum Immunol. 2012;73:1061-7 pubmed 出版商
Le Campion A, Pommier A, Delpoux A, Stouvenel L, Auffray C, Martin B, et al. IL-2 and IL-7 determine the homeostatic balance between the regulatory and conventional CD4+ T cell compartments during peripheral T cell reconstitution. J Immunol. 2012;189:3339-46 pubmed
Xu H, Menendez S, Schlegelberger B, Bae N, Aplan P, Göhring G, et al. Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model. Blood. 2012;120:3089-97 pubmed 出版商
Johnson L, Jameson S. TGF-? sensitivity restrains CD8+ T cell homeostatic proliferation by enforcing sensitivity to IL-7 and IL-15. PLoS ONE. 2012;7:e42268 pubmed 出版商
Ligons D, Tuncer C, Linowes B, Akcay I, Kurtulus S, Deniz E, et al. CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1. J Biol Chem. 2012;287:34386-99 pubmed 出版商
Pattacini L, Mize G, Graham J, Fluharty T, Graham T, Lingnau K, et al. A novel HIV vaccine adjuvanted by IC31 induces robust and persistent humoral and cellular immunity. PLoS ONE. 2012;7:e42163 pubmed 出版商
Do J, Valujskikh A, Vignali D, Fairchild R, Min B. Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo. Proc Natl Acad Sci U S A. 2012;109:12698-703 pubmed 出版商
Chang P, Lee S, Hu X, Davey G, Duan G, Cho J, et al. Breakdown in repression of IFN-? mRNA leads to accumulation of self-reactive effector CD8+ T cells. J Immunol. 2012;189:701-10 pubmed 出版商
Gasparetto M, Sekulovic S, Zakaryan A, Imren S, Kent D, Humphries R, et al. Varying levels of aldehyde dehydrogenase activity in adult murine marrow hematopoietic stem cells are associated with engraftment and cell cycle status. Exp Hematol. 2012;40:857-66.e5 pubmed 出版商
Pham N, Badovinac V, Harty J. Epitope specificity of memory CD8+ T cells dictates vaccination-induced mortality in LCMV-infected perforin-deficient mice. Eur J Immunol. 2012;42:1488-99 pubmed 出版商
Kim G, Ligons D, Hong C, Luckey M, Keller H, Tai X, et al. An in vivo IL-7 requirement for peripheral Foxp3+ regulatory T cell homeostasis. J Immunol. 2012;188:5859-66 pubmed 出版商
Pham N, Badovinac V, Harty J. Differential role of "Signal 3" inflammatory cytokines in regulating CD8 T cell expansion and differentiation in vivo. Front Immunol. 2011;2:4 pubmed 出版商
Florian M, Dörr K, Niebel A, Daria D, Schrezenmeier H, Rojewski M, et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell. 2012;10:520-30 pubmed 出版商
Alari Pahissa E, Vega Ramos J, Zhang J, Castaño A, Turley S, Villadangos J, et al. Differential effect of CD69 targeting on bystander and antigen-specific T cell proliferation. J Leukoc Biol. 2012;92:145-58 pubmed 出版商
Notake T, Horisawa S, Sanjo H, Miyagawa S, Hida S, Taki S. Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors. J Immunol. 2012;188:4838-45 pubmed 出版商
Sharma A, Chen Q, Nguyen T, Yu Q, Sen J. T cell factor-1 and β-catenin control the development of memory-like CD8 thymocytes. J Immunol. 2012;188:3859-68 pubmed 出版商
Wilson J, Pack C, Lin E, Frost E, Albrecht J, Hadley A, et al. CD8 T cells recruited early in mouse polyomavirus infection undergo exhaustion. J Immunol. 2012;188:4340-8 pubmed 出版商
Roberts N, White A, Jenkinson W, Turchinovich G, Nakamura K, Withers D, et al. Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium. Immunity. 2012;36:427-37 pubmed 出版商
Jiang X, Clark R, Liu L, Wagers A, Fuhlbrigge R, Kupper T. Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity. Nature. 2012;483:227-31 pubmed 出版商
Li Q, Rao R, Vazzana J, Goedegebuure P, Odunsi K, Gillanders W, et al. Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity. J Immunol. 2012;188:3080-7 pubmed 出版商
Saran N, Pommerencke J, Witzlau K, Regelin M, Krueger A. Extra-thymic physiological T lineage progenitor activity is exclusively confined to cells expressing either CD127, CD90, or high levels of CD117. PLoS ONE. 2012;7:e30864 pubmed 出版商
Sugiyama M, Nakato G, Jinnohara T, Akiba H, Okumura K, Ohno H, et al. Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development. Int Immunol. 2012;24:369-78 pubmed 出版商
Liu J, Mercher T, Scholl C, Brumme K, Gilliland D, Zhu N. A functional role for the histone demethylase UTX in normal and malignant hematopoietic cells. Exp Hematol. 2012;40:487-98.e3 pubmed 出版商
Mathieu M, Cotta Grand N, Daudelin J, Boulet S, Lapointe R, Labrecque N. CD40-activated B cells can efficiently prime antigen-specific naïve CD8+ T cells to generate effector but not memory T cells. PLoS ONE. 2012;7:e30139 pubmed 出版商
Iseki M, Omori Miyake M, Xu W, Sun X, Takaki S, Rawlings D, et al. Thymic stromal lymphopoietin (TSLP)-induced polyclonal B-cell activation and autoimmunity are mediated by CD4+ T cells and IL-4. Int Immunol. 2012;24:183-95 pubmed 出版商
Ochiai K, Maienschein Cline M, Mandal M, Triggs J, Bertolino E, Sciammas R, et al. A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat Immunol. 2012;13:300-7 pubmed 出版商
Tan J, O Neill H. Myelopoiesis in spleen-producing distinct dendritic-like cells. J Cell Mol Med. 2012;16:1924-33 pubmed 出版商
Gonzaga R, Matzinger P, Perez Diez A. Resident peritoneal NK cells. J Immunol. 2011;187:6235-42 pubmed 出版商
Yoshizawa K, Nakajima S, Notake T, Miyagawa S, Hida S, Taki S. IL-15-high-responder developing NK cells bearing Ly49 receptors in IL-15-/- mice. J Immunol. 2011;187:5162-9 pubmed 出版商
Wainwright D, Sengupta S, Han Y, Lesniak M. Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors. Neuro Oncol. 2011;13:1308-23 pubmed 出版商
Corfe S, Rottapel R, Paige C. Modulation of IL-7 thresholds by SOCS proteins in developing B lineage cells. J Immunol. 2011;187:3499-510 pubmed 出版商
Bertossi A, Aichinger M, Sansonetti P, Lech M, Neff F, Pal M, et al. Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med. 2011;208:1749-56 pubmed 出版商
Reyes Sandoval A, Wyllie D, Bauza K, Milicic A, Forbes E, Rollier C, et al. CD8+ T effector memory cells protect against liver-stage malaria. J Immunol. 2011;187:1347-57 pubmed 出版商
Kim S, Han S, Withers D, Gaspal F, Bae J, Baik S, et al. CD117? CD3? CD56? OX40Lhigh cells express IL-22 and display an LTi phenotype in human secondary lymphoid tissues. Eur J Immunol. 2011;41:1563-72 pubmed 出版商
Esplin B, Shimazu T, Welner R, Garrett K, Nie L, Zhang Q, et al. Chronic exposure to a TLR ligand injures hematopoietic stem cells. J Immunol. 2011;186:5367-75 pubmed 出版商
Link A, Hardie D, Favre S, Britschgi M, Adams D, Sixt M, et al. Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans. Am J Pathol. 2011;178:1662-75 pubmed 出版商
Yeo C, Fearon D. T-bet-mediated differentiation of the activated CD8+ T cell. Eur J Immunol. 2011;41:60-6 pubmed 出版商
Divekar A, Dubey S, Gangalum P, Singh R. Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieu. J Immunol. 2011;186:924-30 pubmed 出版商
MacNamara K, Oduro K, Martin O, Jones D, McLaughlin M, Choi K, et al. Infection-induced myelopoiesis during intracellular bacterial infection is critically dependent upon IFN-? signaling. J Immunol. 2011;186:1032-43 pubmed 出版商
Åhsberg J, Tsapogas P, Qian H, Zetterblad J, Zandi S, Mansson R, et al. Interleukin-7-induced Stat-5 acts in synergy with Flt-3 signaling to stimulate expansion of hematopoietic progenitor cells. J Biol Chem. 2010;285:36275-84 pubmed 出版商
Ji H, Ehrlich L, Seita J, Murakami P, Doi A, Lindau P, et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature. 2010;467:338-42 pubmed 出版商
Fowler C, Pao L, Blattman J, Greenberg P. SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells. J Immunol. 2010;185:3256-67 pubmed 出版商
Anraku M, Tagawa T, Wu L, Yun Z, Keshavjee S, Zhang L, et al. Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignant mesothelioma. J Immunol. 2010;185:956-66 pubmed 出版商
Obar J, Lefrancois L. Early signals during CD8 T cell priming regulate the generation of central memory cells. J Immunol. 2010;185:263-72 pubmed 出版商
Furmanov K, Elnekave M, Lehmann D, Clausen B, Kotton D, Hovav A. The role of skin-derived dendritic cells in CD8+ T cell priming following immunization with lentivectors. J Immunol. 2010;184:4889-97 pubmed 出版商
Bivas Benita M, Bar L, Gillard G, Kaufman D, Simmons N, Hovav A, et al. Efficient generation of mucosal and systemic antigen-specific CD8+ T-cell responses following pulmonary DNA immunization. J Virol. 2010;84:5764-74 pubmed 出版商
Fewkes N, Krauss A, Guimond M, Meadors J, Dobre S, Mackall C. Pharmacologic modulation of niche accessibility via tyrosine kinase inhibition enhances marrow and thymic engraftment after hematopoietic stem cell transplantation. Blood. 2010;115:4120-9 pubmed 出版商
Hirata Y, Hamanaka S, Onodera M. Transactivation of the dopamine receptor 3 gene by a single provirus integration results in development of B-cell lymphoma in transgenic mice generated from retrovirally transduced embryonic stem cells. Blood. 2010;115:3930-8 pubmed 出版商
Chappaz S, Finke D. The IL-7 signaling pathway regulates lymph node development independent of peripheral lymphocytes. J Immunol. 2010;184:3562-9 pubmed 出版商
Welner R, Esplin B, Garrett K, Pelayo R, Luche H, Fehling H, et al. Asynchronous RAG-1 expression during B lymphopoiesis. J Immunol. 2009;183:7768-77 pubmed 出版商
Zlotoff D, Sambandam A, Logan T, Bell J, Schwarz B, Bhandoola A. CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus. Blood. 2010;115:1897-905 pubmed 出版商
Onai N, Manz M, Schmid M. Isolation of common dendritic cell progenitors (CDP) from mouse bone marrow. Methods Mol Biol. 2010;595:195-203 pubmed 出版商
Rai D, Pham N, Harty J, Badovinac V. Tracking the total CD8 T cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hosts. J Immunol. 2009;183:7672-81 pubmed 出版商
MacKenzie D, Seroogy C. Sustained expression of GRAIL during hematopoiesis results in dysregulated differentiation. Acta Haematol. 2009;122:230-7 pubmed 出版商
Smith E, von Vietinghoff S, Stark M, Zarbock A, Sanders J, Duley A, et al. T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo. J Immunol. 2009;183:5685-93 pubmed 出版商
Carlens J, Wahl B, Ballmaier M, Bulfone Paus S, Forster R, Pabst O. Common gamma-chain-dependent signals confer selective survival of eosinophils in the murine small intestine. J Immunol. 2009;183:5600-7 pubmed 出版商
Nemoto Y, Kanai T, Kameyama K, Shinohara T, Sakamoto N, Totsuka T, et al. Long-lived colitogenic CD4+ memory T cells residing outside the intestine participate in the perpetuation of chronic colitis. J Immunol. 2009;183:5059-68 pubmed 出版商
Withers D, Jaensson E, Gaspal F, McConnell F, Eksteen B, Anderson G, et al. The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals. J Immunol. 2009;183:5079-84 pubmed 出版商
Cui Y, Zhang H, Meadors J, Poon R, Guimond M, Mackall C. Harnessing the physiology of lymphopenia to support adoptive immunotherapy in lymphoreplete hosts. Blood. 2009;114:3831-40 pubmed 出版商
de Vries V, Wasiuk A, Bennett K, Benson M, Elgueta R, Waldschmidt T, et al. Mast cell degranulation breaks peripheral tolerance. Am J Transplant. 2009;9:2270-80 pubmed 出版商
Pham N, Badovinac V, Harty J. A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation. J Immunol. 2009;183:2337-48 pubmed 出版商
Kutlesa S, Zayas J, Valle A, Levy R, Jurecic R. T-cell differentiation of multipotent hematopoietic cell line EML in the OP9-DL1 coculture system. Exp Hematol. 2009;37:909-23 pubmed 出版商
Cridland S, Keys J, Papathanasiou P, Perkins A. Indian hedgehog supports definitive erythropoiesis. Blood Cells Mol Dis. 2009;43:149-55 pubmed 出版商
Wirth T, Badovinac V, Zhao L, DAILEY M, Harty J. Differentiation of central memory CD8 T cells is independent of CD62L-mediated trafficking to lymph nodes. J Immunol. 2009;182:6195-206 pubmed 出版商
Colombetti S, Lévy F, Chapatte L. IL-7 adjuvant treatment enhances long-term tumor-antigen-specific CD8+ T-cell responses after immunization with recombinant lentivector. Blood. 2009;113:6629-37 pubmed 出版商
Vondenhoff M, Greuter M, Goverse G, Elewaut D, Dewint P, Ware C, et al. LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009;182:5439-45 pubmed 出版商
Esplin B, Welner R, Zhang Q, BORGHESI L, Kincade P. A differentiation pathway for B1 cells in adult bone marrow. Proc Natl Acad Sci U S A. 2009;106:5773-8 pubmed 出版商
Archambaud C, Sansoni A, Mingueneau M, Devilard E, Delsol G, Malissen B, et al. STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells. J Immunol. 2009;182:2680-9 pubmed 出版商
French J, Roark C, Born W, O Brien R. Gammadelta T lymphocyte homeostasis is negatively regulated by beta2-microglobulin. J Immunol. 2009;182:1892-900 pubmed 出版商
Wirth T, Pham N, Harty J, Badovinac V. High initial frequency of TCR-transgenic CD8 T cells alters inflammation and pathogen clearance without affecting memory T cell function. Mol Immunol. 2009;47:71-8 pubmed 出版商
McGeachy M, Chen Y, Tato C, Laurence A, Joyce Shaikh B, Blumenschein W, et al. The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat Immunol. 2009;10:314-24 pubmed 出版商
Leignadier J, Hardy M, Cloutier M, Rooney J, Labrecque N. Memory T-lymphocyte survival does not require T-cell receptor expression. Proc Natl Acad Sci U S A. 2008;105:20440-5 pubmed 出版商
Sheridan B, Cherpes T, Urban J, Kalinski P, Hendricks R. Reevaluating the CD8 T-cell response to herpes simplex virus type 1: involvement of CD8 T cells reactive to subdominant epitopes. J Virol. 2009;83:2237-45 pubmed 出版商
Vondenhoff M, van de Pavert S, Dillard M, Greuter M, Goverse G, Oliver G, et al. Lymph sacs are not required for the initiation of lymph node formation. Development. 2009;136:29-34 pubmed 出版商
Kraus Z, Haring J, Bishop G. TNF receptor-associated factor 5 is required for optimal T cell expansion and survival in response to infection. J Immunol. 2008;181:7800-9 pubmed
Fujii T, Tomita T, Kanai T, Nemoto Y, Totsuka T, Sakamoto N, et al. FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow. Eur J Immunol. 2008;38:3290-303 pubmed 出版商
Adoro S, Erman B, Sarafova S, Van Laethem F, Park J, Feigenbaum L, et al. Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic. J Immunol. 2008;181:6975-83 pubmed
Dengler H, Baracho G, Omori S, Bruckner S, Arden K, Castrillon D, et al. Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation. Nat Immunol. 2008;9:1388-98 pubmed 出版商
Tang C, Yamada H, Shibata K, Muta H, Wajjwalku W, Podack E, et al. A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection. J Immunol. 2008;181:6316-27 pubmed
MartIn Fontecha A, Baumjohann D, Guarda G, Reboldi A, Hons M, Lanzavecchia A, et al. CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming. J Exp Med. 2008;205:2561-74 pubmed 出版商
Kaufman D, Liu J, Carville A, Mansfield K, Havenga M, Goudsmit J, et al. Trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination. J Immunol. 2008;181:4188-98 pubmed
Liston A, Lu L, O Carroll D, Tarakhovsky A, Rudensky A. Dicer-dependent microRNA pathway safeguards regulatory T cell function. J Exp Med. 2008;205:1993-2004 pubmed 出版商
Zhou X, Jeker L, Fife B, Zhu S, Anderson M, McManus M, et al. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med. 2008;205:1983-91 pubmed 出版商
Rubinstein M, Lind N, Purton J, Filippou P, Best J, McGhee P, et al. IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood. 2008;112:3704-12 pubmed 出版商
Tomita T, Kanai T, Nemoto Y, Fujii T, Nozaki K, Okamoto R, et al. Colitogenic CD4+ effector-memory T cells actively recirculate in chronic colitic mice. Inflamm Bowel Dis. 2008;14:1630-40 pubmed 出版商
Brinkman C, Sheasley O neill S, Ferguson A, Engelhard V. Activated CD8 T cells redistribute to antigen-free lymph nodes and exhibit effector and memory characteristics. J Immunol. 2008;181:1814-24 pubmed
Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, et al. Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis. Inflamm Bowel Dis. 2008;14:1491-503 pubmed 出版商
Lee S, Park Y, So T, Kwon B, Cheroutre H, Mittler R, et al. Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells. Nat Immunol. 2008;9:917-26 pubmed 出版商
Welner R, Pelayo R, Nagai Y, Garrett K, Wuest T, CARR D, et al. Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection. Blood. 2008;112:3753-61 pubmed 出版商
Aerts N, Dombrecht E, Ebo D, Bridts C, Stevens W, De Clerck L. Activated T cells complicate the identification of regulatory T cells in rheumatoid arthritis. Cell Immunol. 2008;251:109-15 pubmed 出版商
Ramsey C, Rubinstein M, Kim D, Cho J, Sprent J, Surh C. The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15. J Immunol. 2008;180:5320-6 pubmed
Hernandez M, Shen L, Rock K. CD40 on APCs is needed for optimal programming, maintenance, and recall of CD8+ T cell memory even in the absence of CD4+ T cell help. J Immunol. 2008;180:4382-90 pubmed
Desanti G, Cumano A, Golub R. Identification of CD4int progenitors in mouse fetal spleen, a source of resident lymphoid cells. J Leukoc Biol. 2008;83:1145-54 pubmed 出版商
Singh P, Yao Y, Weliver A, Broxmeyer H, Hong S, Chang C. Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow. Stem Cells. 2008;26:1009-16 pubmed 出版商
Löhning M, Hegazy A, Pinschewer D, Busse D, Lang K, Hofer T, et al. Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors. J Exp Med. 2008;205:53-61 pubmed 出版商
Carreras E, Turner S, Paharkova Vatchkova V, Mao A, Dascher C, Kovats S. Estradiol acts directly on bone marrow myeloid progenitors to differentially regulate GM-CSF or Flt3 ligand-mediated dendritic cell differentiation. J Immunol. 2008;180:727-38 pubmed
Pongubala J, Northrup D, Lancki D, Medina K, Treiber T, Bertolino E, et al. Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat Immunol. 2008;9:203-15 pubmed 出版商
Hovav A, Panas M, Rahman S, Sircar P, Gillard G, Cayabyab M, et al. Duration of antigen expression in vivo following DNA immunization modifies the magnitude, contraction, and secondary responses of CD8+ T lymphocytes. J Immunol. 2007;179:6725-33 pubmed
Norris H, Martin A, Lybarger L, Andersen H, Chervenak D, Chervenak R. TCRbeta enhancer activation in early and late lymphoid progenitors. Cell Immunol. 2007;247:59-71 pubmed
Withers D, Kim M, Bekiaris V, Rossi S, Jenkinson W, Gaspal F, et al. The role of lymphoid tissue inducer cells in splenic white pulp development. Eur J Immunol. 2007;37:3240-5 pubmed
Menon S, Chi H, Zhang H, Deng X, Flavell R, Wei N. COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence. Nat Immunol. 2007;8:1236-45 pubmed
Liu S, Lizee G, Lou Y, Liu C, Overwijk W, Wang G, et al. IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells. Int Immunol. 2007;19:1213-21 pubmed
Hovav A, Panas M, Osuna C, Cayabyab M, Autissier P, Letvin N. The impact of a boosting immunogen on the differentiation of secondary memory CD8+ T cells. J Virol. 2007;81:12793-802 pubmed
Kohara H, Omatsu Y, Sugiyama T, Noda M, Fujii N, Nagasawa T. Development of plasmacytoid dendritic cells in bone marrow stromal cell niches requires CXCL12-CXCR4 chemokine signaling. Blood. 2007;110:4153-60 pubmed
McKinstry K, Golech S, Lee W, Huston G, Weng N, Swain S. Rapid default transition of CD4 T cell effectors to functional memory cells. J Exp Med. 2007;204:2199-211 pubmed
Fernandez I, Zeiser R, Karsunky H, Kambham N, Beilhack A, Soderstrom K, et al. CD101 surface expression discriminates potency among murine FoxP3+ regulatory T cells. J Immunol. 2007;179:2808-14 pubmed
Wang X, Uto T, Akagi T, Akashi M, Baba M. Induction of potent CD8+ T-cell responses by novel biodegradable nanoparticles carrying human immunodeficiency virus type 1 gp120. J Virol. 2007;81:10009-16 pubmed
Cush S, Anderson K, Ravneberg D, Weslow Schmidt J, Flano E. Memory generation and maintenance of CD8+ T cell function during viral persistence. J Immunol. 2007;179:141-53 pubmed
Yu Q, Xu M, Sen J. Beta-catenin expression enhances IL-7 receptor signaling in thymocytes during positive selection. J Immunol. 2007;179:126-31 pubmed
Meier D, Bornmann C, Chappaz S, Schmutz S, Otten L, Ceredig R, et al. Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells. Immunity. 2007;26:643-54 pubmed
Rossi S, Kim M, Leibbrandt A, Parnell S, Jenkinson W, Glanville S, et al. RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J Exp Med. 2007;204:1267-72 pubmed
Heuser M, Argiropoulos B, Kuchenbauer F, Yung E, Piper J, Fung S, et al. MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML. Blood. 2007;110:1639-47 pubmed
Stewart C, Walzer T, Robbins S, Malissen B, Vivier E, Prinz I. Germ-line and rearranged Tcrd transcription distinguish bona fide NK cells and NK-like gammadelta T cells. Eur J Immunol. 2007;37:1442-52 pubmed
Hurchla M, Sedy J, Murphy K. Unexpected role of B and T lymphocyte attenuator in sustaining cell survival during chronic allostimulation. J Immunol. 2007;178:6073-82 pubmed
Purton J, Tan J, Rubinstein M, Kim D, Sprent J, Surh C. Antiviral CD4+ memory T cells are IL-15 dependent. J Exp Med. 2007;204:951-61 pubmed
Astrakhan A, Omori M, Nguyen T, Becker Herman S, Iseki M, Aye T, et al. Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development. Nat Immunol. 2007;8:522-31 pubmed
Fuxa M, Busslinger M. Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function. J Immunol. 2007;178:3031-7 pubmed
Tabatabaei Zavareh N, Vlasova A, Greenwood C, Takei F. Characterization of developmental pathway of natural killer cells from embryonic stem cells in vitro. PLoS ONE. 2007;2:e232 pubmed
Arrode G, Hegde R, Mani A, Jin Y, Chebloune Y, Narayan O. Phenotypic and functional analysis of immune CD8+ T cell responses induced by a single injection of a HIV DNA vaccine in mice. J Immunol. 2007;178:2318-27 pubmed
Piao J, Yoshida H, Yeh W, Doi T, Xue X, Yagita H, et al. TNF receptor-associated factor 2-dependent canonical pathway is crucial for the development of Peyer's patches. J Immunol. 2007;178:2272-7 pubmed
Krueger A, von Boehmer H. Identification of a T lineage-committed progenitor in adult blood. Immunity. 2007;26:105-16 pubmed
Rossi S, Jeker L, Ueno T, Kuse S, Keller M, Zuklys S, et al. Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells. Blood. 2007;109:3803-11 pubmed
Krieg C, Boyman O, Fu Y, Kaye J. B and T lymphocyte attenuator regulates CD8+ T cell-intrinsic homeostasis and memory cell generation. Nat Immunol. 2007;8:162-71 pubmed
Sheridan B, Khanna K, Frank G, Hendricks R. Latent virus influences the generation and maintenance of CD8+ T cell memory. J Immunol. 2006;177:8356-64 pubmed
Shklovskaya E, Fazekas de St Groth B. Severely impaired clonal deletion of CD4+ T cells in low-dose irradiated mice: role of T cell antigen receptor and IL-7 receptor signals. J Immunol. 2006;177:8320-30 pubmed
Iwasaki H, Mizuno S, Arinobu Y, Ozawa H, Mori Y, Shigematsu H, et al. The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. Genes Dev. 2006;20:3010-21 pubmed
Hovav A, Cayabyab M, Panas M, Santra S, Greenland J, Geiben R, et al. Rapid memory CD8+ T-lymphocyte induction through priming with recombinant Mycobacterium smegmatis. J Virol. 2007;81:74-83 pubmed
Haring J, Harty J. Aberrant contraction of antigen-specific CD4 T cells after infection in the absence of gamma interferon or its receptor. Infect Immun. 2006;74:6252-63 pubmed
Coles M, Veiga Fernandes H, Foster K, Norton T, Pagakis S, Seddon B, et al. Role of T and NK cells and IL7/IL7r interactions during neonatal maturation of lymph nodes. Proc Natl Acad Sci U S A. 2006;103:13457-62 pubmed
Priatel J, Chen X, Dhanji S, Abraham N, Teh H. RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development. J Immunol. 2006;177:1470-80 pubmed
Krueger A, Garbe A, von Boehmer H. Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. J Exp Med. 2006;203:1977-84 pubmed
Badovinac V, Messingham K, Griffith T, Harty J. TRAIL deficiency delays, but does not prevent, erosion in the quality of "helpless" memory CD8 T cells. J Immunol. 2006;177:999-1006 pubmed
Moulton V, Bushar N, Leeser D, Patke D, Farber D. Divergent generation of heterogeneous memory CD4 T cells. J Immunol. 2006;177:869-76 pubmed
Dhanji S, Chow M, Teh H. Self-antigen maintains the innate antibacterial function of self-specific CD8 T cells in vivo. J Immunol. 2006;177:138-46 pubmed
Bagaeva L, Rao P, Powers J, Segal B. CXC chemokine ligand 13 plays a role in experimental autoimmune encephalomyelitis. J Immunol. 2006;176:7676-85 pubmed
Leithäuser F, Meinhardt Krajina T, Fink K, Wotschke B, Moller P, Reimann J. Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis. Am J Pathol. 2006;168:1898-909 pubmed
Ceredig R, Rauch M, Balciunaite G, Rolink A. Increasing Flt3L availability alters composition of a novel bone marrow lymphoid progenitor compartment. Blood. 2006;108:1216-22 pubmed
Dumon S, Heath V, Tomlinson M, Gottgens B, Frampton J. Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6. Exp Hematol. 2006;34:654-63 pubmed
Yu Q, Park J, Doan L, Erman B, Feigenbaum L, Singer A. Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection. J Exp Med. 2006;203:165-75 pubmed
Marquez M, Ellmeier W, Sanchez Guajardo V, Freitas A, Acuto O, Di Bartolo V. CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens. J Immunol. 2005;175:7388-97 pubmed
Masuda K, Kubagawa H, Ikawa T, Chen C, Kakugawa K, Hattori M, et al. Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors. EMBO J. 2005;24:4052-60 pubmed
Lu M, Tayu R, Ikawa T, Masuda K, Matsumoto I, Mugishima H, et al. The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors. J Immunol. 2005;175:5848-56 pubmed
Zhong W, Reinherz E. CD8 alpha alpha homodimer expression and role in CD8 T cell memory generation during influenza virus A infection in mice. Eur J Immunol. 2005;35:3103-10 pubmed
French J, Roark C, Born W, O Brien R. {gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells. Proc Natl Acad Sci U S A. 2005;102:14741-6 pubmed
Kuhl C, Atzberger A, Iborra F, Nieswandt B, Porcher C, Vyas P. GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1. Mol Cell Biol. 2005;25:8592-606 pubmed
Tussiwand R, Onai N, Mazzucchelli L, Manz M. Inhibition of natural type I IFN-producing and dendritic cell development by a small molecule receptor tyrosine kinase inhibitor with Flt3 affinity. J Immunol. 2005;175:3674-80 pubmed
Lawrence H, Christensen J, Fong S, Hu Y, Weissman I, Sauvageau G, et al. Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Blood. 2005;106:3988-94 pubmed
Harfst E, Andersson J, Grawunder U, Ceredig R, Rolink A. Homeostatic and functional analysis of mature B cells in lambda5-deficient mice. Immunol Lett. 2005;101:173-84 pubmed
Fujimura S, Xing Y, Takeya M, Yamashita Y, Ohshima K, Kuwahara K, et al. Increased expression of germinal center-associated nuclear protein RNA-primase is associated with lymphomagenesis. Cancer Res. 2005;65:5925-34 pubmed
Benz C, Bleul C. A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision. J Exp Med. 2005;202:21-31 pubmed
Iwasaki H, Somoza C, Shigematsu H, Duprez E, Iwasaki Arai J, Mizuno S, et al. Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation. Blood. 2005;106:1590-600 pubmed
Erlandsson L, Licence S, Gaspal F, Lane P, Corcoran A, Martensson I. Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo. Eur J Immunol. 2005;35:1969-76 pubmed
Min B, Yamane H, Hu Li J, Paul W. Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms. J Immunol. 2005;174:6039-44 pubmed
Harman B, Jenkinson W, Parnell S, Rossi S, Jenkinson E, Anderson G. T/B lineage choice occurs prior to intrathymic Notch signaling. Blood. 2005;106:886-92 pubmed
Growney J, Shigematsu H, Li Z, Lee B, Adelsperger J, Rowan R, et al. Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype. Blood. 2005;106:494-504 pubmed
Masuda K, Itoi M, Amagai T, Minato N, Katsura Y, Kawamoto H. Thymic anlage is colonized by progenitors restricted to T, NK, and dendritic cell lineages. J Immunol. 2005;174:2525-32 pubmed
Kim S, Cornberg M, Wang X, Chen H, Selin L, Welsh R. Private specificities of CD8 T cell responses control patterns of heterologous immunity. J Exp Med. 2005;201:523-33 pubmed
Sanchez Guajardo V, Borghans J, Marquez M, Garcia S, Freitas A. Different competitive capacities of Stat4- and Stat6-deficient CD4+ T cells during lymphophenia-driven proliferation. J Immunol. 2005;174:1178-87 pubmed
Cobas M, Wilson A, Ernst B, Mancini S, MacDonald H, Kemler R, et al. Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med. 2004;199:221-9 pubmed
Karsunky H, Merad M, Cozzio A, Weissman I, Manz M. Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J Exp Med. 2003;198:305-13 pubmed
Iwasaki Arai J, Iwasaki H, Miyamoto T, Watanabe S, Akashi K. Enforced granulocyte/macrophage colony-stimulating factor signals do not support lymphopoiesis, but instruct lymphoid to myelomonocytic lineage conversion. J Exp Med. 2003;197:1311-22 pubmed
Ohl L, Henning G, Krautwald S, Lipp M, Hardtke S, Bernhardt G, et al. Cooperating mechanisms of CXCR5 and CCR7 in development and organization of secondary lymphoid organs. J Exp Med. 2003;197:1199-204 pubmed
Tan J, Ernst B, Kieper W, LeRoy E, Sprent J, Surh C. Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells. J Exp Med. 2002;195:1523-32 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD127 Monoclonal Antibody (A7R34), Functional Grade, eBioscience
目录# :
16-1271-85
规格 :
500微克
价格 :
美国395
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
物种 :
小鼠
克隆 :
A7R34
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
CD127 (Interleukin-7, IL-7) is a glycoprotein involved in the regulation of lymphopoiesis. The response of cells to CD127 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. CD127 consists of an alpha chain and a gamma chain. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. CD127 promotes the proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells. The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. Diseases associated with CD127 dysfunction include severe combined immunodeficiency and T cell negative/B cell negative/NK positive severe combined immunodeficiency.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
别名 :
CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R a; IL 7Ra; IL 7Ra; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R a; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Ra; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国