产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD317 (BST2, PDCA-1) Monoclonal Antibody (26F8), Functional Grade, eBioscience™
目录 :
16-3179-80
规格 :
25微克
价格 :
美国157
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
26F8
反应物种 :
人类
应用 :
免疫细胞化学, 中和反应, 流式细胞仪
更多信息或购买 :
文章摘录数: 10
出版应用/物种/样本/稀释 | 参考文献 |
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Ishikawa J, Kaisho T, Tomizawa H, Lee B, Kobune Y, Inazawa J, et al. Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth. Genomics. 1995;26:527-34 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD317 (BST2, PDCA-1) Monoclonal Antibody (26F8), Functional Grade, eBioscience™
目录# :
16-3179-80
规格 :
25微克
价格 :
美国157
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 0.125 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent
物种 :
人类
克隆 :
26F8
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
BST2 (CD317, HM1.24 antigen, DAMP-2, tetherin) is an integral membrane protein that is involved in the development and growth of B-cells. The surface expression of BST2 on fibroblast cell lines facilitated the stromal cell-dependent growth of DW34, a pre-B-cell line. BST2 is highly expressed during B-cell development, from pro-B precursors to plasma cells, T-cells, monocytes, NK cells and DCs (at protein level), and myeloma cells. Research studies have shown that BST2 also functions as an inhibitor of retrovirus release from human cells whose activity is antagonized by the HIV-1 accessory protein, Vpu. While BST2 causes retention of virions on cell surfaces or endocytosis into BST2-positive compartments, its depletion abolished the viral requirement for Vpu for virus release, an activity that may represent a potential therapeutic strategy for the treatment of HIV/AIDS. Another disease associated with BST2 dysfunction is stomatitis.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.125 µg/test, Functional assay: Assay-Dependent, Neutralization: Assay-Dependent
别名 :
2310015I10Rik; Bone marrow stromal antigen 2; bone marrow stromal cell antigen 2; Bst2; BST-2; C87040; CD317; Damp1; DAMP-1; DAMP-1 protein homolog; GREG; HM1.24 antigen; NPC-A-7; PDCA-1; protein DAMP-1; TETHERIN
更多信息或购买 :
公司信息
赛默飞世尔
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