产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD324 (E-Cadherin) Monoclonal Antibody (DECMA-1), Functional Grade, eBioscience™
目录 :
16-3249-85
规格 :
500微克
价格 :
美国368
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
DECMA-1
反应物种 :
人类, 小鼠,
应用 :
免疫组化, 免疫细胞化学, 中和反应, 流式细胞仪
更多信息或购买 :
文章摘录数: 48
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:800; 图 6a
Cetera M, Leybova L, Woo F, Deans M, Devenport D. Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns. Dev Biol. 2017;428:188-203 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:150
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  • 流式细胞仪; 小鼠; 图 6
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Li L, Hu Y, Chen D, Zhu J, Bao W, Xu X, et al. CMTM5 inhibits the development of prostate cancer via the EGFR/PI3K/AKT signaling pathway. Mol Med Rep. 2022;25: pubmed 出版商
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Hsu S, Chou L, Hong C, Chang M, Tsai C, Tian Y, et al. Crosstalk between E-Cadherin/β-Catenin and NF-κB Signaling Pathways: The Regulation of Host-Pathogen Interaction during Leptospirosis. Int J Mol Sci. 2021;22: pubmed 出版商
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Zeng X, Liao H, Wang F. MicroRNA-384 inhibits nasopharyngeal carcinoma growth and metastasis via binding to Smad5 and suppressing the Wnt/β-catenin axis. Cytotechnology. 2021;73:203-215 pubmed 出版商
Kim J, Mahiddine F, Kim G. Leptin Modulates the Metastasis of Canine Inflammatory Mammary Adenocarcinoma Cells Through Downregulation of Lysosomal Protective Protein Cathepsin A (CTSA). Int J Mol Sci. 2020;21: pubmed 出版商
Ramovs V, Krotenberg Garcia A, Kreft M, Sonnenberg A. Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis. J Invest Dermatol. 2020;: pubmed 出版商
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Kim H, Takegahara N, Walsh M, Choi Y. CD44 Can Compensate for IgSF11 Deficiency by Associating with the Scaffold Protein PSD-95 during Osteoclast Differentiation. Int J Mol Sci. 2020;21: pubmed 出版商
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Bornes L, van Scheppingen R, Beerling E, Schelfhorst T, Ellenbroek S, Seinstra D, et al. Fsp1-Mediated Lineage Tracing Fails to Detect the Majority of Disseminating Cells Undergoing EMT. Cell Rep. 2019;29:2565-2569.e3 pubmed 出版商
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Flood B, Manils J, Nulty C, Flis E, Kenealy S, Barber G, et al. Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis. Oncogene. 2019;38:2658-2674 pubmed 出版商
Ostrin E, Little D, Gerner Mauro K, Sumner E, Ríos Corzo R, Ambrosio E, et al. β-Catenin maintains lung epithelial progenitors after lung specification. Development. 2018;145: pubmed 出版商
Chua C, Epsi N, Leung E, Xuan S, Lei M, Li B, et al. Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation. elife. 2018;7: pubmed 出版商
Heck B, Devenport D. Trans-endocytosis of Planar Cell Polarity Complexes during Cell Division. Curr Biol. 2017;27:3725-3733.e4 pubmed 出版商
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed 出版商
Hannezo E, Scheele C, Moad M, Drogo N, Heer R, Sampogna R, et al. A Unifying Theory of Branching Morphogenesis. Cell. 2017;171:242-255.e27 pubmed 出版商
Lyons Cohen M, Thomas S, Cook D, Nakano H. Precision-cut Mouse Lung Slices to Visualize Live Pulmonary Dendritic Cells. J Vis Exp. 2017;: pubmed 出版商
Meinicke H, Bremser A, Brack M, Schrenk K, Pircher H, Izcue A. KLRG1 impairs regulatory T-cell competitive fitness in the gut. Immunology. 2017;152:65-73 pubmed 出版商
Nakano H, Lyons Cohen M, Whitehead G, Nakano K, Cook D. Distinct functions of CXCR4, CCR2, and CX3CR1 direct dendritic cell precursors from the bone marrow to the lung. J Leukoc Biol. 2017;101:1143-1153 pubmed 出版商
Scheele C, Hannezo E, Muraro M, Zomer A, Langedijk N, van Oudenaarden A, et al. Identity and dynamics of mammary stem cells during branching morphogenesis. Nature. 2017;542:313-317 pubmed 出版商
Latil M, Nassar D, Beck B, Boumahdi S, Wang L, Brisebarre A, et al. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition. Cell Stem Cell. 2017;20:191-204.e5 pubmed 出版商
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Kashyap M, Rochman Y, Spolski R, Samsel L, Leonard W. Thymic stromal lymphopoietin is produced by dendritic cells. J Immunol. 2011;187:1207-11 pubmed 出版商
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Liu W, Nelson C, Pirone D, Chen C. E-cadherin engagement stimulates proliferation via Rac1. J Cell Biol. 2006;173:431-41 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD324 (E-Cadherin) Monoclonal Antibody (DECMA-1), Functional Grade, eBioscience™
目录# :
16-3249-85
规格 :
500微克
价格 :
美国368
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
狗, 人类, 小鼠
应用 :
Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Neutralization: Assay-Dependent
物种 :
狗, 人类, 小鼠
克隆 :
DECMA-1
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg/test, Functional assay: Assay-Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Neutralization: Assay-Dependent
别名 :
AA960649; Arc-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; Cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-Cadherin phospho; Epithelial cadherin; hab; half baked; LCAM; L-CAM; phospho cadherin 1; phospho E-Cadherin; phospho LCAM; phospho S838; phospho UVO; S840; S840 E-Cadherin; Ser840; Ser840 E-Cadherin; Um; UVO; Uvomorulin
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国