产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IFNAR1 Monoclonal Antibody (MAR1-5A3), Functional Grade, eBioscience
目录 :
16-5945-85
规格 :
500微克
价格 :
美国534
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MAR1-5A3
反应物种 :
小鼠
应用 :
中和反应, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 小鼠
Gürtler C, Carty M, Kearney J, Schattgen S, Ding A, Fitzgerald K, et al. SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter. J Immunol. 2014;192:4821-32 pubmed 出版商
Olson G, Murray T, Jahn A, Mai D, Diercks A, Gold E, et al. Type I interferon decreases macrophage energy metabolism during mycobacterial infection. Cell Rep. 2021;35:109195 pubmed 出版商
Zhang L, Jiang X, Pfau D, Ling Y, Nathan C. Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death. J Exp Med. 2021;218: pubmed 出版商
Zhou Y, Li M, Lv T, Huang M, Cheng B, Zhang Y, et al. Gastrodin Inhibits Virus Infection by Promoting the Production of Type I Interferon. Front Pharmacol. 2020;11:608707 pubmed 出版商
Ku J, Chen Y, Lim B, Gasser S, Crasta K, Gan Y. Bacterial-induced cell fusion is a danger signal triggering cGAS-STING pathway via micronuclei formation. Proc Natl Acad Sci U S A. 2020;117:15923-15934 pubmed 出版商
Hosseini S, Michaelsen Preusse K, Grigoryan G, Chhatbar C, Kalinke U, Korte M. Type I Interferon Receptor Signaling in Astrocytes Regulates Hippocampal Synaptic Plasticity and Cognitive Function of the Healthy CNS. Cell Rep. 2020;31:107666 pubmed 出版商
Lomakova Y, Londregan J, Maslanka J, Goldman N, Somerville J, Riggs J. PHA eludes macrophage suppression to activate CD8+ T cells. Immunobiology. 2019;224:94-101 pubmed 出版商
Lindqvist R, Kurhade C, Gilthorpe J, Overby A. Cell-type- and region-specific restriction of neurotropic flavivirus infection by viperin. J Neuroinflammation. 2018;15:80 pubmed 出版商
Goldman N, Lomakova Y, Londregan J, Bucknum A, DePierri K, Somerville J, et al. High macrophage PD-L1 expression not responsible for T cell suppression. Cell Immunol. 2018;324:50-58 pubmed 出版商
Gibb D, Liu J, Santhanakrishnan M, Natarajan P, Madrid D, Patel S, et al. B cells require Type 1 interferon to produce alloantibodies to transfused KEL-expressing red blood cells in mice. Transfusion. 2017;57:2595-2608 pubmed 出版商
Troegeler A, Mercier I, Cougoule C, Pietretti D, Colom A, Duval C, et al. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells. Proc Natl Acad Sci U S A. 2017;114:E540-E549 pubmed 出版商
Lindqvist R, Mundt F, Gilthorpe J, Wölfel S, Gekara N, Kröger A, et al. Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects. J Neuroinflammation. 2016;13:277 pubmed
Takagi H, Arimura K, Uto T, Fukaya T, Nakamura T, Choijookhuu N, et al. Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation. Sci Rep. 2016;6:24477 pubmed 出版商
Hotz C, Roetzer L, Huber T, Sailer A, Oberson A, Treinies M, et al. TLR and RLR Signaling Are Reprogrammed in Opposite Directions after Detection of Viral Infection. J Immunol. 2015;195:4387-95 pubmed 出版商
Nakashima C, Otsuka A, Kitoh A, Honda T, Egawa G, Nakajima S, et al. Basophils regulate the recruitment of eosinophils in a murine model of irritant contact dermatitis. J Allergy Clin Immunol. 2014;134:100-7 pubmed 出版商
Grinenko T, Arndt K, Portz M, Mende N, Günther M, Cosgun K, et al. Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells. J Exp Med. 2014;211:209-15 pubmed 出版商
Chen Y, Chen T, Pai L, Wesoly J, Bluyssen H, Lee C. A type I IFN-Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors. J Exp Med. 2013;210:2515-22 pubmed 出版商
Kole A, He J, Rivollier A, Silveira D, Kitamura K, Maloy K, et al. Type I IFNs regulate effector and regulatory T cell accumulation and anti-inflammatory cytokine production during T cell-mediated colitis. J Immunol. 2013;191:2771-9 pubmed 出版商
Rodriguez Gomez M, Talke Y, Goebel N, Hermann F, Reich B, Mack M. Basophils support the survival of plasma cells in mice. J Immunol. 2010;185:7180-5 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
IFNAR1 Monoclonal Antibody (MAR1-5A3), Functional Grade, eBioscience
目录# :
16-5945-85
规格 :
500微克
价格 :
美国534
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
小鼠
应用 :
Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
物种 :
小鼠
克隆 :
MAR1-5A3
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
格式 :
液体
应用w/稀释 :
Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
别名 :
alpha-type antiviral protein; AVP; beta-type antiviral protein; CD118; CRF2-1; cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; H3K1; Ifar; IFN R1; IFNalpha/beta R1; IFN-alpha/beta receptor 1; IFN-alpha/betaR; IFNalpha/betaR1; IFN-alpha/betaR1; IFN-alpha/betaRalpha; IFNalpha/beta-Ralpha; IFN-alpha-REC; IFNAR; Ifnar1; IFNBR; IFNR1; IFN-R-1; Ifrc; INF-a receptor; Infar; interferon (alpha and beta) receptor 1; interferon (alpha, beta and omega) receptor 1; interferon alpha and beta receptor subunit 1; interferon alpha/beta receptor 1; interferon receptor 1; interferon-alpha/beta receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国