产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Podoplanin Monoclonal Antibody (NZ-1.3), Functional Grade, eBioscience
目录 :
16-9381-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
NZ-1.3
反应物种 :
人类
应用 :
免疫组化, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 人类; 图 1e
Croft A, Campos J, Jansen K, Turner J, Marshall J, Attar M, et al. Distinct fibroblast subsets drive inflammation and damage in arthritis. Nature. 2019;570:246-251 pubmed 出版商
  • 流式细胞仪; 人类; 图 4
Harfuddin Z, Dharmadhikari B, Wong S, Duan K, Poidinger M, Kwajah S, et al. Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype. Sci Rep. 2016;6:29712 pubmed 出版商
  • 免疫组化; 人类; 图 2k
Brunner P, Glitzner E, Reininger B, Klein I, Stary G, Mildner M, et al. CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin. Exp Dermatol. 2015;24:522-8 pubmed 出版商
Al Hosni R, Bozec L, Roberts S, Cheema U. Reprogramming bone progenitor identity and potency through control of collagen density and oxygen tension. iScience. 2022;25:104059 pubmed 出版商
Chen W, Ding Y, Liu D, Lu Z, Wang Y, Yuan Y. Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis. PLoS Pathog. 2021;17:e1009600 pubmed 出版商
Wilkus K, Brodaczewska K, Kajdasz A, Kieda C. Distinctive Properties of Endothelial Cells from Tumor and Normal Tissue in Human Breast Cancer. Int J Mol Sci. 2021;22: pubmed 出版商
He J, Yan J, Wang J, Zhao L, Xin Q, Zeng Y, et al. Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses. Cell Res. 2021;31:742-757 pubmed 出版商
Kanagaki S, Ikeo S, Suezawa T, Yamamoto Y, Seki M, Hirai T, et al. Directed induction of alveolar type I cells derived from pluripotent stem cells via Wnt signaling inhibition. Stem Cells. 2021;39:156-169 pubmed 出版商
He N, van Iperen L, de Jong D, Szuhai K, Helmerhorst F, van der Westerlaken L, et al. Human Extravillous Trophoblasts Penetrate Decidual Veins and Lymphatics before Remodeling Spiral Arteries during Early Pregnancy. PLoS ONE. 2017;12:e0169849 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
Podoplanin Monoclonal Antibody (NZ-1.3), Functional Grade, eBioscience
目录# :
16-9381-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
人类
应用 :
Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent
物种 :
人类
克隆 :
NZ-1.3
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight. Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue. Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells. Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC. Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm. Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent
别名 :
29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国