产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IFN beta Monoclonal Antibody (A1 (IFNb)), Functional Grade, eBioscience
目录 :
16-9978-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
A1(IFNb)
反应物种 :
人类
应用 :
中和反应, 抑制或激活实验
更多信息或购买 :
文章摘录数: 2
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 人类; 图 5a
Decalf J, Desdouits M, Rodrigues V, Gobert F, Gentili M, Marques Ladeira S, et al. Sensing of HIV-1 Entry Triggers a Type I Interferon Response in Human Primary Macrophages. J Virol. 2017;91: pubmed 出版商
Coelho L, Magno de Freitas Almeida G, Mennechet F, Blangy A, Uze G. Interferon-alpha and -beta differentially regulate osteoclastogenesis: role of differential induction of chemokine CXCL11 expression. Proc Natl Acad Sci U S A. 2005;102:11917-22 pubmed
产品信息
产品类型 :
抗体
产品名称 :
IFN beta Monoclonal Antibody (A1 (IFNb)), Functional Grade, eBioscience
目录# :
16-9978-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
物种 :
人类
克隆 :
A1(IFNb)
抗体亚型 :
IgG1, kappa
储存 :
4° C
描述 :
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
格式 :
液体
应用w/稀释 :
Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent
别名 :
Fibroblast interferon; Ifb; IFF; IFN b; IFN ß; IFNB; Ifnb1; IFNbeta; IFN-beta; IFNß; Interferon b; Interferon beta; interferon beta 1; interferon beta 1, fibroblast; interferon beta protein; interferon, beta 1; interferon, beta 1, fibroblast; interferon-beta; RP11-113D19.1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国