产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD11b Monoclonal Antibody (M1/70), APC, eBioscience™
目录 :
17-0112-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
APC
克隆名称 :
M1/70
反应物种 :
小鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 339
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:100; 图 s3-1c
Li J, Zhang L, Zheng Y, Shao R, Liang Q, Yu W, et al. BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 e1a, e1c
Vagnozzi R, Maillet M, Sargent M, Khalil H, Johansen A, Schwanekamp J, et al. An acute immune response underlies the benefit of cardiac stem cell therapy. Nature. 2020;577:405-409 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:10; 图 s3a
Kobayakawa K, Ohkawa Y, Yoshizaki S, Tamaru T, Saito T, Kijima K, et al. Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. Sci Adv. 2019;5:eaav5086 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1e
Lu D, Liao Y, Zhu S, Chen Q, Xie D, Liao J, et al. Bone-derived Nestin-positive mesenchymal stem cells improve cardiac function via recruiting cardiac endothelial cells after myocardial infarction. Stem Cell Res Ther. 2019;10:127 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 3c
Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, et al. Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nat Commun. 2019;10:1365 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 5c
Rosenzweig N, Dvir Szternfeld R, Tsitsou Kampeli A, Keren Shaul H, Ben Yehuda H, Weill Raynal P, et al. PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model. Nat Commun. 2019;10:465 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:300; 图 s7b
Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:1000; 图 s3e
Tsiantoulas D, Sage A, Göderle L, Ozsvar Kozma M, Murphy D, Porsch F, et al. BAFF Neutralization Aggravates Atherosclerosis. Circulation. 2018;: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400; 图 s1a
Zhang Y, Xia F, Liu X, Yu Z, Xie L, Liu L, et al. JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/?-catenin/CCND1 signaling. J Clin Invest. 2018;128:1737-1751 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4b
Zhao B, Mei Y, Cao L, Zhang J, Sumagin R, Yang J, et al. Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms. J Clin Invest. 2018;128:125-140 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Mingay M, Chaturvedi A, Bilenky M, Cao Q, Jackson L, Hui T, et al. Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia. Leukemia. 2018;32:11-20 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:50; 图 s2
Guo W, Liu W, Chen Z, Gu Y, Peng S, Shen L, et al. Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis. Nat Commun. 2017;8:2168 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3a
Medaglia C, Giladi A, Stoler Barak L, De Giovanni M, Salame T, Biram A, et al. Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq. Science. 2017;358:1622-1626 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s5
Hara T, Nakaoka H, Hayashi T, Mimura K, Hoshino D, Inoue M, et al. Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes. Proc Natl Acad Sci U S A. 2017;114:E4416-E4424 pubmed 出版商
  • 流式细胞仪; 小鼠
  • 免疫组化; 小鼠; 图 s3i
Tammela T, Sanchez Rivera F, Cetinbas N, Wu K, Joshi N, Helenius K, et al. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature. 2017;545:355-359 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200
Thomas D, Clare S, Sowerby J, Pardo M, Juss J, Goulding D, et al. Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity. J Exp Med. 2017;214:1111-1128 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3c
Li H, Liu P, Xu S, Li Y, Dekker J, Li B, et al. FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging. J Clin Invest. 2017;127:1241-1253 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Zhang H, Qi Y, Yuan Y, Cai L, Xu H, Zhang L, et al. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation. Sci Rep. 2017;7:41887 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Ishiguro T, Fukawa T, Akaki K, Nagaoka K, Takeda T, Iwakura Y, et al. Absence of DCIR1 reduces the mortality rate of endotoxemic hepatitis in mice. Eur J Immunol. 2017;47:704-712 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Zhou Z, Tang Y, Jin X, Chen C, Lu Y, Liu L, et al. Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NF?B Pathway Suppression. J Diabetes Res. 2016;2016:4847812 pubmed
  • 流式细胞仪; 小鼠; 1:800; 表 1
Jackson Jones L, Duncan S, Magalhaes M, Campbell S, Maizels R, McSorley H, et al. Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nat Commun. 2016;7:12651 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 1
Shiraishi M, Shintani Y, Shintani Y, Ishida H, Saba R, Yamaguchi A, et al. Alternatively activated macrophages determine repair of the infarcted adult murine heart. J Clin Invest. 2016;126:2151-66 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:250; 图 6
Ufimtseva E. Differences between Mycobacterium-Host Cell Relationships in Latent Tuberculous Infection of Mice Ex Vivo and Mycobacterial Infection of Mouse Cells In Vitro. J Immunol Res. 2016;2016:4325646 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Xu J, Zhou L, Ji L, Chen F, Fortmann K, Zhang K, et al. The REGγ-proteasome forms a regulatory circuit with IκBÉ› and NFκB in experimental colitis. Nat Commun. 2016;7:10761 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Atkinson S, Hoffmann U, Hamann A, Bach E, Danneskiold Samsøe N, Kristiansen K, et al. Depletion of regulatory T cells leads to an exacerbation of delayed-type hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade. Dis Model Mech. 2016;9:427-40 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Povinelli B, Kokolus K, Eng J, Dougher C, Curtin L, Capitano M, et al. Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells. PLoS ONE. 2015;10:e0120078 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4e
Hu Lieskovan S, Mok S, Homet Moreno B, Tsoi J, Robert L, Goedert L, et al. Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma. Sci Transl Med. 2015;7:279ra41 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4
Karsten C, Laumonnier Y, Eurich B, Ender F, Bröker K, Roy S, et al. Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse. J Immunol. 2015;194:1841-55 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200
Orre M, Kamphuis W, Osborn L, Jansen A, Kooijman L, Bossers K, et al. Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction. Neurobiol Aging. 2014;35:2746-2760 pubmed 出版商
  • 流式细胞仪; 小鼠; 表 1
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed 出版商
  • 流式细胞仪; 小鼠
Panjwani N, Mulvihill E, Longuet C, Yusta B, Campbell J, Brown T, et al. GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice. Endocrinology. 2013;154:127-39 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Tait E, Jordan K, Dupont C, Harris T, Gregg B, Wilson E, et al. Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells. J Immunol. 2010;185:1502-12 pubmed 出版商
Xu J, Zanvit P, Hu L, Tseng P, Liu N, Wang F, et al. The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching. Immunity. 2020;53:371-383.e5 pubmed 出版商
Wagner J, Wong P, Schappe T, Berrien Elliott M, Cubitt C, Jaeger N, et al. Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity. Cell Rep. 2020;31:107720 pubmed 出版商
Tan Q, Zhou C, Cheng L, Luo M, Liu C, Xu W, et al. Immunotherapy of Bacillus Calmette‑Guérin by targeting macrophages against bladder cancer in a NOD/scid IL2Rg‑/‑ mouse model. Mol Med Rep. 2020;22:362-370 pubmed 出版商
Zhang Z, Dong L, Jia A, Chen X, Yang Q, Wang Y, et al. Glucocorticoids Promote the Onset of Acute Experimental Colitis and Cancer by Upregulating mTOR Signaling in Intestinal Epithelial Cells. Cancers (Basel). 2020;12: pubmed 出版商
Zhong L, Yao L, Tower R, Wei Y, Miao Z, Park J, et al. Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment. elife. 2020;9: pubmed 出版商
Sidwell T, Liao Y, Garnham A, Vasanthakumar A, Gloury R, Blume J, et al. Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis. Nat Commun. 2020;11:252 pubmed 出版商
Ren C, Yuan Q, Jian X, Randazzo P, Tang W, Wu D. Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization. J Immunol. 2020;204:1012-1021 pubmed 出版商
Hidalgo San Jose L, Sunshine M, Dillingham C, Chua B, Krutá M, Hong Y, et al. Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal. Cell Rep. 2020;30:69-80.e6 pubmed 出版商
Zhang Y, Li S, Liu Q, Long R, Feng J, Qin H, et al. Mycobacterium tuberculosis Heat-Shock Protein 16.3 Induces Macrophage M2 Polarization Through CCRL2/CX3CR1. Inflammation. 2020;43:487-506 pubmed 出版商
Wang C, Li Q, Lv J, Sun X, Cao Y, Yu K, et al. Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury. Mucosal Immunol. 2019;: pubmed 出版商
Zhang X, Feng J, Chen S, Yang H, Dong Z. Synergized regulation of NK cell education by NKG2A and specific Ly49 family members. Nat Commun. 2019;10:5010 pubmed 出版商
Tuit S, Salvagno C, Kapellos T, Hau C, Seep L, Oestreich M, et al. Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients. Cell Rep. 2019;29:1221-1235.e5 pubmed 出版商
Wettersten H, Weis S, Pathria P, von Schalscha T, Minami T, Varner J, et al. Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression. Cancer Res. 2019;79:5048-5059 pubmed 出版商
Zhou Y, Fu C, Kong Y, Pan D, Wang Y, Huang S, et al. Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models. Anticancer Drugs. 2019;30:909-916 pubmed 出版商
Bartholomew T, Kidd T, Sá Pessoa J, Conde Alvarez R, Bengoechea J. 2-Hydroxylation of Acinetobacter baumannii Lipid A Contributes to Virulence. Infect Immun. 2019;87: pubmed 出版商
Hao X, Gu H, Chen C, Huang D, Zhao Y, Xie L, et al. Metabolic Imaging Reveals a Unique Preference of Symmetric Cell Division and Homing of Leukemia-Initiating Cells in an Endosteal Niche. Cell Metab. 2019;29:950-965.e6 pubmed 出版商
Hirakata T, Lee H, Ohba M, Saeki K, Okuno T, Murakami A, et al. Dietary ω-3 fatty acids alter the lipid mediator profile and alleviate allergic conjunctivitis without modulating Th2 immune responses. FASEB J. 2019;33:3392-3403 pubmed 出版商
Wang X, Zhao Z, Zhang H, Hou J, Feng W, Zhang M, et al. Simultaneous isolation of mesenchymal stem cells and endothelial progenitor cells derived from murine bone marrow. Exp Ther Med. 2018;16:5171-5177 pubmed 出版商
Chaudhury S, O Connor C, Cañete A, Bittencourt Silvestre J, Sarrou E, Prendergast Á, et al. Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias. Nat Commun. 2018;9:5280 pubmed 出版商
Beneke V, Küster F, Neehus A, Hesse C, Lopez Rodriguez E, Haake K, et al. An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages. Sci Rep. 2018;8:16281 pubmed 出版商
Deloch L, Rückert M, Fietkau R, Frey B, Gaipl U. Low-Dose Radiotherapy Has No Harmful Effects on Key Cells of Healthy Non-Inflamed Joints. Int J Mol Sci. 2018;19: pubmed 出版商
Lainez N, Jonak C, Nair M, Ethell I, Wilson E, Carson M, et al. Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice. Front Immunol. 2018;9:1992 pubmed 出版商
Bai Y, Yang Y, Mu X, Lin G, Wang Y, Jin S, et al. Hydrogen Sulfide Alleviates Acute Myocardial Ischemia Injury by Modulating Autophagy and Inflammation Response under Oxidative Stress. Oxid Med Cell Longev. 2018;2018:3402809 pubmed 出版商
Jiang J, Gao Q, Gong Y, Huang L, Lin H, Zhou X, et al. MiR-486 promotes proliferation and suppresses apoptosis in myeloid cells by targeting Cebpa in vitro. Cancer Med. 2018;7:4627-4638 pubmed 出版商
Omata Y, Frech M, Primbs T, Lucas S, Andreev D, Scholtysek C, et al. Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice. Cell Rep. 2018;24:169-180 pubmed 出版商
Hardy R, Fenton C, Croft A, Naylor A, Begum R, Desanti G, et al. 11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis. J Autoimmun. 2018;92:104-113 pubmed 出版商
Hirota K, Hashimoto M, Ito Y, Matsuura M, Ito H, Tanaka M, et al. Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis. Immunity. 2018;48:1220-1232.e5 pubmed 出版商
Mertens B, Cristina de Araujo Nogueira T, Topalis D, Stranska R, Snoeck R, Andrei G. Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice. Oncotarget. 2018;9:21978-22000 pubmed 出版商
Mitchell K, Barreyro L, Todorova T, Taylor S, Antony Debré I, Narayanagari S, et al. IL1RAP potentiates multiple oncogenic signaling pathways in AML. J Exp Med. 2018;215:1709-1727 pubmed 出版商
Lorentsen K, Cho J, Luo X, Zuniga A, Urban J, Zhou L, et al. Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma. Nat Commun. 2018;9:1679 pubmed 出版商
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed 出版商
Wang T, Wang D, Yu H, Feng B, Zhou F, Zhang H, et al. A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors. Nat Commun. 2018;9:1532 pubmed 出版商
Pesaresi M, Bonilla Pons S, Simonte G, Sanges D, Di Vicino U, Cosma M. Endogenous Mobilization of Bone-Marrow Cells Into the Murine Retina Induces Fusion-Mediated Reprogramming of Müller Glia Cells. EBioMedicine. 2018;30:38-51 pubmed 出版商
Noailles A, Maneu V, Campello L, Lax P, Cuenca N. Systemic inflammation induced by lipopolysaccharide aggravates inherited retinal dystrophy. Cell Death Dis. 2018;9:350 pubmed 出版商
Lim D, Kim W, Lee C, Bae H, Kim J. Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung. Front Physiol. 2018;9:47 pubmed 出版商
Kulkarni U, Herrmenau C, Win S, Bauer M, Kamradt T. IL-7 treatment augments and prolongs sepsis-induced expansion of IL-10-producing B lymphocytes and myeloid-derived suppressor cells. PLoS ONE. 2018;13:e0192304 pubmed 出版商
Barnette D, Cahill T, Gunadasa Rohling M, Carr C, Freeman M, Riley P. iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction. JCI Insight. 2018;3: pubmed 出版商
Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172:517-533.e20 pubmed 出版商
Briere D, Sudhakar N, Woods D, Hallin J, Engstrom L, Aranda R, et al. The class I/IV HDAC inhibitor mocetinostat increases tumor antigen presentation, decreases immune suppressive cell types and augments checkpoint inhibitor therapy. Cancer Immunol Immunother. 2018;67:381-392 pubmed 出版商
Liron T, Raphael B, Hiram Bab S, Bab I, Gabet Y. Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes. J Cell Physiol. 2018;233:371-377 pubmed 出版商
Guo X, Chu L, Ke F, Mu L, Li Z, Cai J, et al. Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells. Oncotarget. 2017;8:108981-108988 pubmed 出版商
Mei Y, Feng G, Rahimi N, Zhao B, Zhang J, Cao L, et al. Loss of mDia1 causes neutropenia via attenuated CD11b endocytosis and increased neutrophil adhesion to the endothelium. Blood Adv. 2017;1:1650-1656 pubmed 出版商
Stephen J, Scales H, Benson R, Erben D, Garside P, Brewer J. Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity. NPJ Vaccines. 2017;2:1 pubmed 出版商
Wang Y, Xiao M, Tao C, Chen J, Wang Z, Yang J, et al. Inactivation of mTORC1 Signaling in Osterix-expressing Cells Impairs B-cell Differentiation. J Bone Miner Res. 2017;: pubmed 出版商
Tran M, Hamada M, Jeon H, Shiraishi R, Asano K, Hattori M, et al. MafB is a critical regulator of complement component C1q. Nat Commun. 2017;8:1700 pubmed 出版商
Kim H, Nam S, Mun S, Lee S, Kim H, Park Y, et al. DJ-1 controls bone homeostasis through the regulation of osteoclast differentiation. Nat Commun. 2017;8:1519 pubmed 出版商
Wang X, Zhang Y, Wang Z, Liu X, Zhu G, Han G, et al. Anti?IL?39 (IL?23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus?like mice. Mol Med Rep. 2017;: pubmed 出版商
Zhu D, Tan J, Maleken A, Muljadi R, Chan S, Lau S, et al. Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury. Stem Cell Res Ther. 2017;8:257 pubmed 出版商
Zhang B, Zhang J, Shi H, Mao F, Wang J, Yan Y, et al. A novel method to isolate mesenchymal stem cells from mouse umbilical cord. Mol Med Rep. 2017;: pubmed 出版商
Zamanian Daryoush M, Lindner D, DiDonato J, Wagner M, Buffa J, Rayman P, et al. Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer. Oncotarget. 2017;8:71965-71980 pubmed 出版商
Xu Y, Wang Y, Yan S, Yang Q, Zhou Y, Zeng X, et al. Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation. Nat Commun. 2017;8:943 pubmed 出版商
Fodil N, Moradin N, Leung V, Olivier J, Radovanovic I, Jeyakumar T, et al. CCDC88B is required for pathogenesis of inflammatory bowel disease. Nat Commun. 2017;8:932 pubmed 出版商
Qin Y, Wu L, Ouyang Y, Zhou P, Zhou H, Wang Y, et al. MiR-125a Is a critical modulator for neutrophil development. PLoS Genet. 2017;13:e1007027 pubmed 出版商
Valanparambil R, Tam M, Gros P, Auger J, Segura M, Gros P, et al. IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection. PLoS Pathog. 2017;13:e1006647 pubmed 出版商
Sato Kaneko F, Yao S, Ahmadi A, Zhang S, Hosoya T, Kaneda M, et al. Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer. JCI Insight. 2017;2: pubmed 出版商
Kersten K, Coffelt S, Hoogstraat M, Verstegen N, Vrijland K, Ciampricotti M, et al. Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages. Oncoimmunology. 2017;6:e1334744 pubmed 出版商
YEKU O, Purdon T, Koneru M, Spriggs D, Brentjens R. Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment. Sci Rep. 2017;7:10541 pubmed 出版商
Lai C, Strange D, Wong T, LEHRER A, Verma S. Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4. Front Microbiol. 2017;8:1571 pubmed 出版商
Wang S, Xia P, Chen Y, Qu Y, Xiong Z, Ye B, et al. Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation. Cell. 2017;171:201-216.e18 pubmed 出版商
Jiao Y, Li Z, Loughran P, Fan E, Scott M, Li Y, et al. Frontline Science: Macrophage-derived exosomes promote neutrophil necroptosis following hemorrhagic shock. J Leukoc Biol. 2017;: pubmed 出版商
Schwartz C, Khan A, Floudas A, Saunders S, Hams E, Rodewald H, et al. ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control. J Exp Med. 2017;214:2507-2521 pubmed 出版商
Ehx G, Fransolet G, de Leval L, D Hondt S, Lucas S, Hannon M, et al. Azacytidine prevents experimental xenogeneic graft-versus-host disease without abrogating graft-versus-leukemia effects. Oncoimmunology. 2017;6:e1314425 pubmed 出版商
Vijay R, Fehr A, Janowski A, Athmer J, Wheeler D, Grunewald M, et al. Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling. Proc Natl Acad Sci U S A. 2017;114:E5444-E5453 pubmed 出版商
Katsura A, Tamura Y, Hokari S, Harada M, Morikawa M, Sakurai T, et al. ZEB1-regulated inflammatory phenotype in breast cancer cells. Mol Oncol. 2017;11:1241-1262 pubmed 出版商
Young C, Rorke E, Adhikary G, Xu W, Eckert R. Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype. Cell Death Dis. 2017;8:e2840 pubmed 出版商
Kawasaki T, Ito K, Miyata H, Akira S, Kawai T. Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice. EMBO J. 2017;36:1707-1718 pubmed 出版商
Friedrich C, Mamareli P, Thiemann S, Kruse F, Wang Z, Holzmann B, et al. MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium. PLoS Pathog. 2017;13:e1006357 pubmed 出版商
Kienhöfer D, Hahn J, Stoof J, Csepregi J, Reinwald C, Urbonaviciute V, et al. Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps. JCI Insight. 2017;2: pubmed 出版商
Aziz M, Cui K, Das M, Brown K, Ardell C, Febbraio M, et al. The Upregulation of Integrin ?D?2 (CD11d/CD18) on Inflammatory Macrophages Promotes Macrophage Retention in Vascular Lesions and Development of Atherosclerosis. J Immunol. 2017;198:4855-4867 pubmed 出版商
De Giorgi M, Enjyoji K, Jiang G, Csizmadia E, Mitsuhashi S, Gumina R, et al. Complete deletion of Cd39 is atheroprotective in apolipoprotein E-deficient mice. J Lipid Res. 2017;58:1292-1305 pubmed 出版商
Westerterp M, Gautier E, Ganda A, Molusky M, Wang W, Fotakis P, et al. Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity. Cell Metab. 2017;25:1294-1304.e6 pubmed 出版商
Schneider R, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, van Strien P, et al. Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target. Cell Stem Cell. 2017;20:785-800.e8 pubmed 出版商
Koh A, Sinder B, Entezami P, Nilsson L, McCauley L. The skeletal impact of the chemotherapeutic agent etoposide. Osteoporos Int. 2017;28:2321-2333 pubmed 出版商
Jatana S, Palmer B, Phelan S, Gelein R, Delouise L. In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation. Part Fibre Toxicol. 2017;14:12 pubmed 出版商
Fabian K, Chi Sabins N, Taylor J, Fecek R, Weinstein A, Storkus W. Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice. Oncoimmunology. 2017;6:e1290035 pubmed 出版商
Hérault A, Binnewies M, Leong S, Calero Nieto F, Zhang S, Kang Y, et al. Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis. Nature. 2017;544:53-58 pubmed 出版商
Zhang B, Wang B, Cao S, Wang Y, Wu D. Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-?B signaling and NLRP3 activation. Int J Mol Med. 2017;39:1111-1118 pubmed 出版商
Peake K, Manning J, Lewis C, Tran K, Rossi F, Krieger C. Bone Marrow-Derived Cell Accumulation in the Spinal Cord Is Independent of Peripheral Mobilization in a Mouse Model of Amyotrophic Lateral Sclerosis. Front Neurol. 2017;8:75 pubmed 出版商
Jin W, Shi S, Li Z, Li M, Wood K, Gonzales R, et al. Depletion of microglia exacerbates postischemic inflammation and brain injury. J Cereb Blood Flow Metab. 2017;37:2224-2236 pubmed 出版商
Hensel J, Khattar V, Ashton R, Lee C, Siegal G, Ponnazhagan S. Location of tumor affects local and distant immune cell type and number. Immun Inflamm Dis. 2017;5:85-94 pubmed 出版商
Bou Nasser Eddine F, Forlani G, Lombardo L, Tedeschi A, Tosi G, Accolla R. CIITA-driven MHC class II expressing tumor cells can efficiently prime naive CD4+ TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells. Oncoimmunology. 2017;6:e1261777 pubmed 出版商
Khameneh H, Ho A, Laudisi F, Derks H, Kandasamy M, Sivasankar B, et al. C5a Regulates IL-1β Production and Leukocyte Recruitment in a Murine Model of Monosodium Urate Crystal-Induced Peritonitis. Front Pharmacol. 2017;8:10 pubmed 出版商
Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed 出版商
Seleme M, Kosmac K, Jonjic S, Britt W. Tumor Necrosis Factor Alpha-Induced Recruitment of Inflammatory Mononuclear Cells Leads to Inflammation and Altered Brain Development in Murine Cytomegalovirus-Infected Newborn Mice. J Virol. 2017;91: pubmed 出版商
Liu J, Xue Y, Dong D, Xiao C, Lin C, Wang H, et al. CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion. Mucosal Immunol. 2017;10:1145-1159 pubmed 出版商
Zhao X, Guo Y, Jiang C, Chang Q, Zhang S, Luo T, et al. JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression. Nat Med. 2017;23:337-346 pubmed 出版商
Xia L, Plachynta M, Liu T, Xiao X, Song J, Li X, et al. Pro-inflammatory effect of a traditional Chinese medicine formula with potent anti-cancer activity in vitro impedes tumor inhibitory potential in vivo. Mol Clin Oncol. 2016;5:717-723 pubmed 出版商
Wang W, Wang H, Zhou X, Li X, Sun W, Dellinger M, et al. Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice. J Bone Miner Res. 2017;32:939-950 pubmed 出版商
Zha Q, Wei H, Li C, Liang Y, Xu L, Bai W, et al. ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages. Front Immunol. 2016;7:597 pubmed 出版商
Owusu Boaitey N, Bauckman K, Zhang T, Mysorekar I. Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner. Immun Inflamm Dis. 2016;4:413-426 pubmed
Wang Y, Golden J, Fritz Y, Zhang X, Diaconu D, Camhi M, et al. Interleukin 6 regulates psoriasiform inflammation-associated thrombosis. JCI Insight. 2016;1:e89384 pubmed 出版商
Monfared M, Minaee B, Rastegar T, Khrazinejad E, Barbarestani M. Sertoli cell condition medium can induce germ like cells from bone marrow derived mesenchymal stem cells. Iran J Basic Med Sci. 2016;19:1186-1192 pubmed
Kuchmiy A, D Hont J, Hochepied T, Lamkanfi M. NLRP2 controls age-associated maternal fertility. J Exp Med. 2016;213:2851-2860 pubmed
Cheng H, Ang H, A El Farran C, Li P, Fang H, Liu T, et al. Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors. Nat Commun. 2016;7:13396 pubmed 出版商
Jiang X, Zhou T, Xiao Y, Yu J, Dou S, Chen G, et al. Tim-3 promotes tumor-promoting M2 macrophage polarization by binding to STAT1 and suppressing the STAT1-miR-155 signaling axis. Oncoimmunology. 2016;5:e1211219 pubmed
Chudnovskiy A, Mortha A, Kana V, Kennard A, Ramírez J, Rahman A, et al. Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. Cell. 2016;167:444-456.e14 pubmed 出版商
Perobelli S, Mercadante A, Galvani R, Gonçalves Silva T, Alves A, Pereira Neves A, et al. G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way. J Immunol. 2016;197:3725-3734 pubmed
Sochalska M, Schuler F, Weiss J, Prchal Murphy M, Sexl V, Villunger A. MYC selects against reduced BCL2A1/A1 protein expression during B cell lymphomagenesis. Oncogene. 2017;36:2066-2073 pubmed 出版商
Vila Leahey A, Oldford S, Marignani P, Wang J, Haidl I, Marshall J. Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice. Oncoimmunology. 2016;5:e1151591 pubmed 出版商
Yang M, Chen S, Du J, He J, Wang Y, Li Z, et al. NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nat Commun. 2016;7:12730 pubmed 出版商
Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed 出版商
Veinotte L, Gebremeskel S, Johnston B. CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFN? production and tumor control. Oncoimmunology. 2016;5:e1160979 pubmed 出版商
Di Siena S, Gimmelli R, Nori S, Barbagallo F, Campolo F, Dolci S, et al. Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury. Cell Death Dis. 2016;7:e2317 pubmed 出版商
Gravano D, Al Kuhlani M, Davini D, Sanders P, Manilay J, Hoyer K. CD8+ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure. J Autoimmun. 2016;75:58-67 pubmed 出版商
Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed 出版商
Johnson A, Qin Y, Cozzo A, Freemerman A, Huang M, Zhao L, et al. Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation. Mol Metab. 2016;5:506-526 pubmed 出版商
McCullough L, Mirza M, Xu Y, Bentivegna K, Steffens E, Ritzel R, et al. Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones. Aging (Albany NY). 2016;8:1432-41 pubmed 出版商
Barrett N, Malouf C, Kapeni C, Bacon W, Giotopoulos G, Jacobsen S, et al. Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016;16:1039-1054 pubmed 出版商
Schmidt D, Peterlik D, Reber S, Lechner A, Männel D. Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice. PLoS ONE. 2016;11:e0159059 pubmed 出版商
Ben Shoshan S, Kagan P, Sultan M, Barabash Z, Dor C, Jacob Hirsch J, et al. ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis. RNA Biol. 2017;14:587-602 pubmed 出版商
Zheng H, Zou W, Shen J, Xu L, Wang S, Fu Y, et al. Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth. Stem Cells Transl Med. 2016;5:1216-28 pubmed 出版商
Ochi T, Feng Y, Kitamoto S, Nagao Kitamoto H, Kuffa P, Atarashi K, et al. Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine. Sci Rep. 2016;6:27634 pubmed 出版商
Yan H, Zhou H, Akk A, Hu Y, Springer L, Ennis T, et al. Neutrophil Proteases Promote Experimental Abdominal Aortic Aneurysm via Extracellular Trap Release and Plasmacytoid Dendritic Cell Activation. Arterioscler Thromb Vasc Biol. 2016;36:1660-1669 pubmed 出版商
Xu Y, Liu Y, Yang C, Kang L, Wang M, Hu J, et al. Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses. Immunology. 2016;149:157-71 pubmed 出版商
Möhle L, Mattei D, Heimesaat M, Bereswill S, Fischer A, Alutis M, et al. Ly6C(hi) Monocytes Provide a Link between Antibiotic-Induced Changes in Gut Microbiota and Adult Hippocampal Neurogenesis. Cell Rep. 2016;15:1945-56 pubmed 出版商
Michlmayr D, Bardina S, Rodriguez C, Pletnev A, Lim J. Dual Function of Ccr5 during Langat Virus Encephalitis: Reduction in Neutrophil-Mediated Central Nervous System Inflammation and Increase in T Cell-Mediated Viral Clearance. J Immunol. 2016;196:4622-31 pubmed 出版商
Binsfeld M, Muller J, Lamour V, De Veirman K, De Raeve H, Bellahcène A, et al. Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma. Oncotarget. 2016;7:37931-37943 pubmed 出版商
Collins S, Chan Li Y, Oh M, Vigeland C, Limjunyawong N, Mitzner W, et al. Vaccinia vaccine-based immunotherapy arrests and reverses established pulmonary fibrosis. JCI Insight. 2016;1:e83116 pubmed
Ren K, Jin C, Ma P, Ren Q, Jia Z, Zhu D. Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype. J Ginseng Res. 2016;40:196-202 pubmed 出版商
Yong C, John L, Devaud C, Prince M, Johnstone R, Trapani J, et al. A role for multiple chimeric antigen receptor-expressing leukocytes in antigen-specific responses to cancer. Oncotarget. 2016;7:34582-98 pubmed 出版商
Moradin N, Torre S, Gauthier S, Tam M, Hawari J, Vandercruyssen K, et al. Cysteamine broadly improves the anti-plasmodial activity of artemisinins against murine blood stage and cerebral malaria. Malar J. 2016;15:260 pubmed 出版商
Kober C, Weibel S, Rohn S, Kirscher L, Szalay A. Intratumoral INF-? triggers an antiviral state in GL261 tumor cells: a major hurdle to overcome for oncolytic vaccinia virus therapy of cancer. Mol Ther Oncolytics. 2015;2:15009 pubmed 出版商
Fu A, Hung K, Yuen M, Zhou X, Mak D, Chan I, et al. IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline. Proc Natl Acad Sci U S A. 2016;113:E2705-13 pubmed 出版商
Valanparambil R, Tam M, Jardim A, Geary T, Stevenson M. Primary Heligmosomoides polygyrus bakeri infection induces myeloid-derived suppressor cells that suppress CD4+ Th2 responses and promote chronic infection. Mucosal Immunol. 2017;10:238-249 pubmed 出版商
Jin X, Liu L, Zhou Z, Ge J, Yao T, Shen C. Pioglitazone alleviates inflammation in diabetic mice fed a high-fat diet via inhibiting advanced glycation end-product-induced classical macrophage activation. FEBS J. 2016;283:2295-308 pubmed 出版商
Vandenberk L, Garg A, Verschuere T, Koks C, Belmans J, Beullens M, et al. Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma. Oncoimmunology. 2016;5:e1083669 pubmed
Kuffova L, Knickelbein J, Yu T, Medina C, Amescua G, Rowe A, et al. High-Risk Corneal Graft Rejection in the Setting of Previous Corneal Herpes Simplex Virus (HSV)-1 Infection. Invest Ophthalmol Vis Sci. 2016;57:1578-87 pubmed 出版商
Esterházy D, Loschko J, London M, Jove V, Oliveira T, Mucida D. Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance. Nat Immunol. 2016;17:545-55 pubmed 出版商
Bravo B, Gallego M, Flores A, Bornstein R, Puente Bedia A, Hernandez J, et al. Restrained Th17 response and myeloid cell infiltration into the central nervous system by human decidua-derived mesenchymal stem cells during experimental autoimmune encephalomyelitis. Stem Cell Res Ther. 2016;7:43 pubmed 出版商
Vila Leahey A, Rogers D, Marshall J. The impact of ranitidine on monocyte responses in the context of solid tumors. Oncotarget. 2016;7:10891-904 pubmed 出版商
Wex K, Schmid U, Just S, Wang X, Wurm R, Naumann M, et al. Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages. Front Immunol. 2015;6:650 pubmed 出版商
Ying W, Tseng A, Chang R, Wang H, Lin Y, Kanameni S, et al. miR-150 regulates obesity-associated insulin resistance by controlling B cell functions. Sci Rep. 2016;6:20176 pubmed 出版商
Li W, Zhang X, Chen Y, Xie Y, Liu J, Feng Q, et al. G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers. Protein Cell. 2016;7:130-40 pubmed 出版商
Chu C, Gardner P, Copland D, Liyanage S, Gonzalez Cordero A, Kleine Holthaus S, et al. Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model. Dis Model Mech. 2016;9:473-81 pubmed 出版商
Lakshminarayanan V, Supekar N, Wei J, McCurry D, Dueck A, Kosiorek H, et al. MUC1 Vaccines, Comprised of Glycosylated or Non-Glycosylated Peptides or Tumor-Derived MUC1, Can Circumvent Immunoediting to Control Tumor Growth in MUC1 Transgenic Mice. PLoS ONE. 2016;11:e0145920 pubmed 出版商
Watari K, Shibata T, Nabeshima H, Shinoda A, Fukunaga Y, Kawahara A, et al. Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice. Sci Rep. 2016;6:19470 pubmed 出版商
Bazett M, Bergeron M, Haston C. Streptomycin treatment alters the intestinal microbiome, pulmonary T cell profile and airway hyperresponsiveness in a cystic fibrosis mouse model. Sci Rep. 2016;6:19189 pubmed 出版商
Traka M, Podojil J, McCarthy D, Miller S, Popko B. Oligodendrocyte death results in immune-mediated CNS demyelination. Nat Neurosci. 2016;19:65-74 pubmed 出版商
Ribeiro L, Loures F, de Araújo E, Feriotti C, Costa T, Serezani C, et al. Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis. Mediators Inflamm. 2015;2015:852574 pubmed 出版商
Dudek M, Puttur F, Arnold Schrauf C, Kühl A, Holzmann B, Henriques Normark B, et al. Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection. Mucosal Immunol. 2016;9:1288-302 pubmed 出版商
Johnson K, Kong G, Gao X, Chang Y, Hewitt K, Sanalkumar R, et al. Cis-regulatory mechanisms governing stem and progenitor cell transitions. Sci Adv. 2015;1:e1500503 pubmed 出版商
Yu H, Sui Y, Wang Y, Sato N, Frey B, Xia Z, et al. Interleukin-15 Constrains Mucosal T Helper 17 Cell Generation: Influence of Mononuclear Phagocytes. PLoS ONE. 2015;10:e0143001 pubmed 出版商
HENRY C, Casás Selves M, Kim J, Zaberezhnyy V, Aghili L, Daniel A, et al. Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors. J Clin Invest. 2015;125:4666-80 pubmed 出版商
Ghanem L, Kromer A, Silverman I, Chatterji P, Traxler E, Penzo Méndez A, et al. The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development. Mol Cell Biol. 2016;36:304-19 pubmed 出版商
Yong C, Westwood J, Schröder J, Papenfuss A, von Scheidt B, Moeller M, et al. Expression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic Mice. PLoS ONE. 2015;10:e0140543 pubmed 出版商
Tokieda S, Komori M, Ishiguro T, Iwakura Y, Takahara K, Inaba K. Dendritic cell immunoreceptor 1 alters neutrophil responses in the development of experimental colitis. BMC Immunol. 2015;16:64 pubmed 出版商
Olsen D, Goar W, Nichols B, Bailey K, Christensen S, Merriam K, et al. Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model. Biomed Res Int. 2015;2015:975789 pubmed 出版商
Natrajan M, de la Fuente A, Crawford A, Linehan E, Nuñez V, Johnson K, et al. Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination. Brain. 2015;138:3581-97 pubmed 出版商
Soki F, Cho S, Kim Y, Jones J, Park S, Koh A, et al. Bone marrow macrophages support prostate cancer growth in bone. Oncotarget. 2015;6:35782-96 pubmed 出版商
Matthews G, Mehdipour P, Cluse L, Falkenberg K, Wang E, Roth M, et al. Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies. Blood. 2015;126:2392-403 pubmed 出版商
Ying W, Tseng A, Chang R, Morin A, Brehm T, Triff K, et al. MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation. J Clin Invest. 2015;125:4149-59 pubmed 出版商
Hu Z, Pei G, Wang P, Yang J, Zhu F, Guo Y, et al. Biliverdin Reductase A (BVRA) Mediates Macrophage Expression of Interleukin-10 in Injured Kidney. Int J Mol Sci. 2015;16:22621-35 pubmed 出版商
Ofotokun I, Titanji K, Vikulina T, Roser Page S, Yamaguchi M, Zayzafoon M, et al. Role of T-cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss. Nat Commun. 2015;6:8282 pubmed 出版商
Lim S, Kim W, Kim Y, Lee S, Koo J, Lee J, et al. dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis. Nat Commun. 2015;6:8244 pubmed 出版商
Neri T, Muggeo S, Paulis M, Caldana M, Crisafulli L, Strina D, et al. Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts. Stem Cell Reports. 2015;5:558-68 pubmed 出版商
Febinger H, Thomasy H, Pavlova M, Ringgold K, Barf P, George A, et al. Time-dependent effects of CX3CR1 in a mouse model of mild traumatic brain injury. J Neuroinflammation. 2015;12:154 pubmed 出版商
Radjabova V, Mastroeni P, Skjødt K, Zaccone P, de Bono B, Goodall J, et al. TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils. J Immunol. 2015;195:3149-59 pubmed 出版商
Krneta T, Gillgrass A, Chew M, Ashkar A. The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cell Mol Immunol. 2016;13:628-39 pubmed 出版商
Bahnan W, Boettner D, Westermark L, Fällman M, Schesser K. Pathogenic Yersinia Promotes Its Survival by Creating an Acidic Fluid-Accessible Compartment on the Macrophage Surface. PLoS ONE. 2015;10:e0133298 pubmed 出版商
Grosjean F, Nasi S, Schneider P, Chobaz V, Liu A, Mordasini V, et al. Dendritic Cells Cause Bone Lesions in a New Mouse Model of Histiocytosis. PLoS ONE. 2015;10:e0133917 pubmed 出版商
Ray A, Castillo E, Morris K, Nofchissey R, Weston L, Samedi V, et al. Blockade of MK2 is protective in inflammation-associated colorectal cancer development. Int J Cancer. 2016;138:770-5 pubmed 出版商
Jiang C, Hu X, Wang L, Cheng H, Lin Y, Pang Y, et al. Excessive proliferation and impaired function of primitive hematopoietic cells in bone marrow due to senescence post chemotherapy in a T cell acute lymphoblastic leukemia model. J Transl Med. 2015;13:234 pubmed 出版商
Huang J, Meng S, Hong S, Lin X, Jin W, Dong C. IL-17C is required for lethal inflammation during systemic fungal infection. Cell Mol Immunol. 2016;13:474-83 pubmed 出版商
Vogel A, Brown D. Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells. Front Immunol. 2015;6:327 pubmed 出版商
Wahid H, Dorian C, Chin P, Hutchinson M, Rice K, Olson D, et al. Toll-Like Receptor 4 Is an Essential Upstream Regulator of On-Time Parturition and Perinatal Viability in Mice. Endocrinology. 2015;156:3828-41 pubmed 出版商
Jin X, Yao T, Zhou Z, Zhu J, Zhang S, Hu W, et al. Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway. Biomed Res Int. 2015;2015:732450 pubmed 出版商
Vaeth M, Zee I, Concepcion A, Maus M, Shaw P, Portal Celhay C, et al. Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells. J Immunol. 2015;195:1202-17 pubmed 出版商
Huang L, Kong Y, Wang J, Sun J, Shi Q, Qiu Y. Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway. Mol Med Rep. 2015;12:4187-4195 pubmed 出版商
Balasubramani A, Larjo A, Bassein J, Chang X, Hastie R, Togher S, et al. Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex. Nat Commun. 2015;6:7307 pubmed 出版商
Fond A, Lee C, Schulman I, Kiss R, Ravichandran K. Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1. J Clin Invest. 2015;125:2748-58 pubmed 出版商
Ito M, Shichita T, Okada M, Komine R, Noguchi Y, Yoshimura A, et al. Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury. Nat Commun. 2015;6:7360 pubmed 出版商
Erny D, HrabÄ› de Angelis A, Jaitin D, Wieghofer P, Staszewski O, David E, et al. Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci. 2015;18:965-77 pubmed 出版商
Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed 出版商
Draghiciu O, Nijman H, Hoogeboom B, Meijerhof T, Daemen T. Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication. Oncoimmunology. 2015;4:e989764 pubmed
Pamir N, Liu N, Irwin A, Becker L, Peng Y, Ronsein G, et al. Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion. J Biol Chem. 2015;290:14656-67 pubmed 出版商
Tabariès S, Ouellet V, Hsu B, Annis M, Rose A, Meunier L, et al. Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases. Breast Cancer Res. 2015;17:45 pubmed 出版商
Koh H, Chang C, Jeon S, Yoon H, Ahn Y, Kim H, et al. The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia. Nat Commun. 2015;6:6340 pubmed 出版商
Li W, Yu R, Ma B, Yang Y, Jiao X, Liu Y, et al. Core fucosylation of IgG B cell receptor is required for antigen recognition and antibody production. J Immunol. 2015;194:2596-606 pubmed 出版商
Li M, Burns T, Kumar S, Morgan A, Sloan S, Palmer T. Aging-like changes in the transcriptome of irradiated microglia. Glia. 2015;63:754-67 pubmed 出版商
Szulzewsky F, Pelz A, Feng X, Synowitz M, Markovic D, Langmann T, et al. Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1. PLoS ONE. 2015;10:e0116644 pubmed 出版商
Micanovic R, Chitteti B, Dagher P, Srour E, Khan S, Hato T, et al. Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis. J Am Soc Nephrol. 2015;26:2172-82 pubmed 出版商
Castellana D, Paus R, Perez Moreno M. Macrophages contribute to the cyclic activation of adult hair follicle stem cells. PLoS Biol. 2014;12:e1002002 pubmed 出版商
Burrack K, Montgomery S, Homann D, Morrison T. CD8+ T cells control Ross River virus infection in musculoskeletal tissues of infected mice. J Immunol. 2015;194:678-89 pubmed 出版商
Schaefer K, Brown N, Kaye P, Lacey C. Cervico-vaginal immunoglobulin G levels increase post-ovulation independently of neutrophils. PLoS ONE. 2014;9:e114824 pubmed 出版商
Cusick M, Libbey J, Doty D, Fujinami R. DA virus mutant H101 has altered CNS pathogenesis and causes immunosuppression. J Neuroimmunol. 2014;277:118-26 pubmed 出版商
Anderson E, Kwee B, Lewin S, Raimondo T, Mehta M, Mooney D. Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia. Tissue Eng Part A. 2015;21:1217-27 pubmed 出版商
Deroost K, Lays N, Pham T, Baci D, Van den Eynde K, Komuta M, et al. Hemozoin induces hepatic inflammation in mice and is differentially associated with liver pathology depending on the Plasmodium strain. PLoS ONE. 2014;9:e113519 pubmed 出版商
Pyzik M, Dumaine A, Dumaine A, Charbonneau B, Fodil Cornu N, Jonjic S, et al. Viral MHC class I-like molecule allows evasion of NK cell effector responses in vivo. J Immunol. 2014;193:6061-9 pubmed 出版商
Boross P, van Montfoort N, Stapels D, van der Poel C, Bertens C, Meeldijk J, et al. FcRγ-chain ITAM signaling is critically required for cross-presentation of soluble antibody-antigen complexes by dendritic cells. J Immunol. 2014;193:5506-14 pubmed 出版商
Chen L, Gibbons D, Goswami S, Cortez M, Ahn Y, Byers L, et al. Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression. Nat Commun. 2014;5:5241 pubmed 出版商
Devaud C, Yong C, John L, Westwood J, Duong C, House C, et al. Foxp3 expression in macrophages associated with RENCA tumors in mice. PLoS ONE. 2014;9:e108670 pubmed 出版商
Toso A, Revandkar A, Di Mitri D, Guccini I, Proietti M, Sarti M, et al. Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity. Cell Rep. 2014;9:75-89 pubmed 出版商
Habbeddine M, Verbeke P, Karaz S, Bobé P, Kanellopoulos Langevin C. Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface. PLoS ONE. 2014;9:e107267 pubmed 出版商
Xiao G, Liu I, Cheng C, Chang C, Lee Y, Cheng W, et al. Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy. PLoS ONE. 2014;9:e106538 pubmed 出版商
Graves C, Harden S, LaPato M, Nelson M, Amador B, Sorenson H, et al. A method for high purity intestinal epithelial cell culture from adult human and murine tissues for the investigation of innate immune function. J Immunol Methods. 2014;414:20-31 pubmed 出版商
Singer K, Delproposto J, Morris D, Zamarron B, Mergian T, Maley N, et al. Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells. Mol Metab. 2014;3:664-75 pubmed 出版商
Hanihara Tatsuzawa F, Miura H, Kobayashi S, Isagawa T, Okuma A, Manabe I, et al. Control of Toll-like receptor-mediated T cell-independent type 1 antibody responses by the inducible nuclear protein I?B-?. J Biol Chem. 2014;289:30925-36 pubmed 出版商
Carvalho da Fonseca A, Wang H, Fan H, Chen X, Zhang I, Zhang L, et al. Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages. J Neuroimmunol. 2014;274:71-7 pubmed 出版商
Doloff J, Chen C, Waxman D. Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2. Mol Cancer. 2014;13:158 pubmed 出版商
Shi M, Shi G, Tang J, Kong D, Bao Y, Xiao B, et al. Myeloid-derived suppressor cell function is diminished in aspirin-triggered allergic airway hyperresponsiveness in mice. J Allergy Clin Immunol. 2014;134:1163-74.e16 pubmed 出版商
El Zaatari M, Chang Y, Zhang M, Franz M, Shreiner A, McDermott A, et al. Tryptophan catabolism restricts IFN-?-expressing neutrophils and Clostridium difficile immunopathology. J Immunol. 2014;193:807-16 pubmed 出版商
Demos Davies K, Ferguson B, Cavasin M, Mahaffey J, Williams S, Spiltoir J, et al. HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling. Am J Physiol Heart Circ Physiol. 2014;307:H252-8 pubmed 出版商
Ju J, Lee H, Oh K, Lee D, Choi E. Kinetics of IFN-? and IL-17 Production by CD4 and CD8 T Cells during Acute Graft-versus-Host Disease. Immune Netw. 2014;14:89-99 pubmed 出版商
Gilmour J, Assi S, Jaegle U, Kulu D, van de Werken H, Clarke D, et al. A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification. Development. 2014;141:2391-401 pubmed 出版商
Wang S, Zhang X, Zhang L, Bryant J, Kheradmand T, Hering B, et al. Preemptive Tolerogenic Delivery of Donor Antigens for Permanent Allogeneic Islet Graft Protection. Cell Transplant. 2015;24:1155-65 pubmed 出版商
Cekanaviciute E, Fathali N, Doyle K, Williams A, Han J, Buckwalter M. Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice. Glia. 2014;62:1227-40 pubmed 出版商
Goh A, Bertin Maghit S, Ping Yeo S, Ho A, Derks H, Mortellaro A, et al. A novel human anti-interleukin-1? neutralizing monoclonal antibody showing in vivo efficacy. MAbs. 2014;6:765-73 pubmed 出版商
Nobuhisa I, Osawa M, Uemura M, Kishikawa Y, Anani M, Harada K, et al. Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters. Mol Cell Biol. 2014;34:1976-90 pubmed 出版商
Haldar M, Kohyama M, So A, Kc W, Wu X, Briseño C, et al. Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages. Cell. 2014;156:1223-1234 pubmed 出版商
Wong T, Doyle A, Lee J, Jelinek D. Eosinophils regulate peripheral B cell numbers in both mice and humans. J Immunol. 2014;192:3548-58 pubmed 出版商
Bezbradica J, Rosenstein R, DeMarco R, Brodsky I, Medzhitov R. A role for the ITAM signaling module in specifying cytokine-receptor functions. Nat Immunol. 2014;15:333-42 pubmed 出版商
Paradis M, Mindt B, Duerr C, Rojas O, Ng D, Boulianne B, et al. A TNF-?-CCL20-CCR6 axis regulates Nod1-induced B cell responses. J Immunol. 2014;192:2787-99 pubmed 出版商
Westphalen K, Gusarova G, Islam M, Subramanian M, Cohen T, Prince A, et al. Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity. Nature. 2014;506:503-6 pubmed 出版商
Suga H, Rennert R, Rodrigues M, Sorkin M, Glotzbach J, Januszyk M, et al. Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing. Stem Cells. 2014;32:1347-60 pubmed 出版商
Feuermann Y, Kang K, Gavrilova O, Haetscher N, Jang S, Yoo K, et al. MiR-193b and miR-365-1 are not required for the development and function of brown fat in the mouse. RNA Biol. 2013;10:1807-14 pubmed 出版商
Heizmann B, Kastner P, Chan S. Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals. J Exp Med. 2013;210:2823-32 pubmed 出版商
Wueest S, Mueller R, Bluher M, Item F, Chin A, Wiedemann M, et al. Fas (CD95) expression in myeloid cells promotes obesity?induced muscle insulin resistance. EMBO Mol Med. 2014;6:43-56 pubmed
Zhang Y, Tang W, Zhang H, Niu X, Xu Y, Zhang J, et al. A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils. Dev Cell. 2013;27:215-226 pubmed 出版商
Fleischman A, Maxson J, Luty S, Agarwal A, Royer L, Abel M, et al. The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition. Blood. 2013;122:3628-31 pubmed 出版商
Devaud C, Westwood J, John L, Flynn J, Paquet Fifield S, Duong C, et al. Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy. Mol Ther. 2014;22:18-27 pubmed 出版商
Orre M, Kamphuis W, Osborn L, Melief J, Kooijman L, Huitinga I, et al. Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice. Neurobiol Aging. 2014;35:1-14 pubmed 出版商
Karlsson F, Martinez N, Gray L, Zhang S, Tsunoda I, Grisham M. Therapeutic evaluation of ex vivo-generated versus natural regulatory T-cells in a mouse model of chronic gut inflammation. Inflamm Bowel Dis. 2013;19:2282-94 pubmed 出版商
Yoshida T, Galvez S, Tiwari S, Rezk B, Semprun Prieto L, Higashi Y, et al. Angiotensin II inhibits satellite cell proliferation and prevents skeletal muscle regeneration. J Biol Chem. 2013;288:23823-32 pubmed 出版商
Zhao H, Roychoudhury J, Doggett T, Apte R, Ferguson T. Age-dependent changes in FasL (CD95L) modulate macrophage function in a model of age-related macular degeneration. Invest Ophthalmol Vis Sci. 2013;54:5321-31 pubmed 出版商
Zamanian Daryoush M, Lindner D, Tallant T, Wang Z, Buffa J, Klipfell E, et al. The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects. J Biol Chem. 2013;288:21237-52 pubmed 出版商
Lampron A, Pimentel Coelho P, Rivest S. Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration. J Comp Neurol. 2013;521:3863-76 pubmed 出版商
Doyle A, Jacobsen E, Ochkur S, Willetts L, Shim K, Neely J, et al. Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing Cre recombinase exclusively in eosinophils. J Leukoc Biol. 2013;94:17-24 pubmed 出版商
Aulner N, Danckaert A, Rouault Hardoin E, Desrivot J, Helynck O, Commere P, et al. High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery. PLoS Negl Trop Dis. 2013;7:e2154 pubmed 出版商
Schmid M, Franco I, Kang S, Hirsch E, Quilliam L, Varner J. PI3-kinase ? promotes Rap1a-mediated activation of myeloid cell integrin ?4?1, leading to tumor inflammation and growth. PLoS ONE. 2013;8:e60226 pubmed 出版商
Zhang Y, Yang P, Sun T, Li D, Xu X, Rui Y, et al. miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat Cell Biol. 2013;15:284-94 pubmed 出版商
Yang X, Jiang X, Chen G, Xiao Y, Geng S, Kang C, et al. T cell Ig mucin-3 promotes homeostasis of sepsis by negatively regulating the TLR response. J Immunol. 2013;190:2068-79 pubmed 出版商
Thurlow L, Joshi G, Clark J, Spontak J, Neely C, Maile R, et al. Functional modularity of the arginine catabolic mobile element contributes to the success of USA300 methicillin-resistant Staphylococcus aureus. Cell Host Microbe. 2013;13:100-7 pubmed 出版商
Grothusen C, Schuett H, Hillmer A, Lumpe S, Grote K, Ballmaier M, et al. Role of suppressor of cytokine signaling-1 in murine atherosclerosis. PLoS ONE. 2012;7:e51608 pubmed 出版商
Jacobson L, Lima H, Goldberg M, Gocheva V, Tsiperson V, Sutterwala F, et al. Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants. J Biol Chem. 2013;288:7481-91 pubmed 出版商
Fernandez Castaneda A, Arandjelovic S, Stiles T, Schlobach R, Mowen K, Gonias S, et al. Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris. J Biol Chem. 2013;288:4538-48 pubmed 出版商
Monk J, Hou T, Turk H, Weeks B, Wu C, McMurray D, et al. Dietary n-3 polyunsaturated fatty acids (PUFA) decrease obesity-associated Th17 cell-mediated inflammation during colitis. PLoS ONE. 2012;7:e49739 pubmed 出版商
Fuertes Marraco S, Grosjean F, Duval A, Rosa M, Lavanchy C, Ashok D, et al. Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research. Front Immunol. 2012;3:331 pubmed 出版商
Kasler H, Lim H, Mottet D, Collins A, Lee I, Verdin E. Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance. EMBO J. 2012;31:4453-65 pubmed 出版商
Wang S, Cao C, Chen Z, BANKAITIS V, Tzima E, Sheibani N, et al. Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation. PLoS ONE. 2012;7:e45499 pubmed 出版商
Johnson K, Hsu A, Ryu M, Wang J, Gao X, Boyer M, et al. Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity. J Clin Invest. 2012;122:3692-704 pubmed 出版商
Liu J, Hettmer S, Milsom M, Hofmann I, Hua F, Miller C, et al. Induction of histiocytic sarcoma in mouse skeletal muscle. PLoS ONE. 2012;7:e44044 pubmed 出版商
Simmons S, Knoll M, Drewell C, Wolf I, Mollenkopf H, Bouquet C, et al. Biphenotypic B-lymphoid/myeloid cells expressing low levels of Pax5: potential targets of BAL development. Blood. 2012;120:3688-98 pubmed 出版商
He H, Xu J, Warren C, Duan D, Li X, Wu L, et al. Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. Blood. 2012;120:3152-62 pubmed 出版商
Ribot J, deBarros A, Mancio Silva L, Pamplona A, Silva Santos B. B7-CD28 costimulatory signals control the survival and proliferation of murine and human ?? T cells via IL-2 production. J Immunol. 2012;189:1202-8 pubmed 出版商
Thornton E, Looney M, Bose O, Sen D, Sheppard D, Locksley R, et al. Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung. J Exp Med. 2012;209:1183-99 pubmed 出版商
Ryu M, Liu Y, Zhong X, Du J, Peterson N, Kong G, et al. Oncogenic Kras expression in postmitotic neurons leads to S100A8-S100A9 protein overexpression and gliosis. J Biol Chem. 2012;287:22948-58 pubmed 出版商
von Brühl M, Stark K, Steinhart A, Chandraratne S, Konrad I, Lorenz M, et al. Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. J Exp Med. 2012;209:819-35 pubmed 出版商
Baumgartner F, Woess C, Pedit V, Tzankov A, Labi V, Villunger A. Minor cell-death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf. Oncogene. 2013;32:621-30 pubmed 出版商
Weiner Z, Boyer A, Gallegos Candela M, Cardani A, Barr J, Glomski I. Debridement increases survival in a mouse model of subcutaneous anthrax. PLoS ONE. 2012;7:e30201 pubmed 出版商
O Connor R, Li X, Blumerman S, Anderton S, Noelle R, Dalton D. Adjuvant immunotherapy of experimental autoimmune encephalomyelitis: immature myeloid cells expressing CXCL10 and CXCL16 attract CXCR3+CXCR6+ and myelin-specific T cells to the draining lymph nodes rather than the central nervous system. J Immunol. 2012;188:2093-101 pubmed 出版商
BRICKEY W, Neuringer I, Walton W, Hua X, Wang E, JHA S, et al. MyD88 provides a protective role in long-term radiation-induced lung injury. Int J Radiat Biol. 2012;88:335-47 pubmed 出版商
Song M, Kang B, Jeon J, Chang J, Lee S, Min C, et al. In vivo imaging of differences in early donor cell proliferation in graft-versus-host disease hosts with different pre-conditioning doses. Mol Cells. 2012;33:79-86 pubmed 出版商
Siggs O, Li X, Xia Y, Beutler B. ZBTB1 is a determinant of lymphoid development. J Exp Med. 2012;209:19-27 pubmed 出版商
Fujimura T, Ring S, Umansky V, Mahnke K, Enk A. Regulatory T cells stimulate B7-H1 expression in myeloid-derived suppressor cells in ret melanomas. J Invest Dermatol. 2012;132:1239-46 pubmed 出版商
Berda Haddad Y, Robert S, Salers P, Zekraoui L, Farnarier C, Dinarello C, et al. Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1?. Proc Natl Acad Sci U S A. 2011;108:20684-9 pubmed 出版商
de Bruin A, Libregts S, Valkhof M, Boon L, Touw I, Nolte M. IFN? induces monopoiesis and inhibits neutrophil development during inflammation. Blood. 2012;119:1543-54 pubmed 出版商
Chan W, Hannah R, Dawson M, Pridans C, Foster D, Joshi A, et al. The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic stem cells. Mol Cell Biol. 2011;31:5046-60 pubmed 出版商
Schmid M, Avraamides C, Foubert P, Shaked Y, Kang S, Kerbel R, et al. Combined blockade of integrin-?4?1 plus cytokines SDF-1? or IL-1? potently inhibits tumor inflammation and growth. Cancer Res. 2011;71:6965-75 pubmed 出版商
Monticelli L, Sonnenberg G, Abt M, Alenghat T, Ziegler C, Doering T, et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol. 2011;12:1045-54 pubmed 出版商
Muto A, Mizoguchi T, Udagawa N, Ito S, Kawahara I, Abiko Y, et al. Lineage-committed osteoclast precursors circulate in blood and settle down into bone. J Bone Miner Res. 2011;26:2978-90 pubmed 出版商
Hemmers S, Teijaro J, Arandjelovic S, Mowen K. PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection. PLoS ONE. 2011;6:e22043 pubmed 出版商
Verjan Garcia N, Umemoto E, Saito Y, Yamasaki M, Hata E, Matozaki T, et al. SIRP?/CD172a regulates eosinophil homeostasis. J Immunol. 2011;187:2268-77 pubmed 出版商
Duraffour S, Matthys P, van den Oord J, De Schutter T, Mitera T, Snoeck R, et al. Study of camelpox virus pathogenesis in athymic nude mice. PLoS ONE. 2011;6:e21561 pubmed 出版商
Libregts S, Gutierrez L, de Bruin A, Wensveen F, Papadopoulos P, van Ijcken W, et al. Chronic IFN-? production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis. Blood. 2011;118:2578-88 pubmed 出版商
Fuertes Marraco S, Scott C, Bouillet P, Ives A, Masina S, Vremec D, et al. Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo. PLoS ONE. 2011;6:e20189 pubmed 出版商
Lindqvist M, Nookaew I, Brinkenberg I, Samuelson E, Thörn K, Nielsen J, et al. Unraveling molecular signatures of immunostimulatory adjuvants in the female genital tract through systems biology. PLoS ONE. 2011;6:e20448 pubmed 出版商
Bennett C, Fallah Arani F, Conlan T, Trouillet C, Goold H, Chorro L, et al. Langerhans cells regulate cutaneous injury by licensing CD8 effector cells recruited to the skin. Blood. 2011;117:7063-9 pubmed 出版商
Choi J, Yoon H, Min C, Choi E. Effects of Pre-conditioning Dose on the Immune Kinetics and Cytokine Production in the Leukocytes Infiltrating GVHD Tissues after MHC-matched Transplantation. Immune Netw. 2011;11:68-78 pubmed 出版商
Stock A, Booth S, Cerundolo V. Prostaglandin E2 suppresses the differentiation of retinoic acid-producing dendritic cells in mice and humans. J Exp Med. 2011;208:761-73 pubmed 出版商
Powolny Budnicka I, Riemann M, Tänzer S, Schmid R, Hehlgans T, Weih F. RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in ?? T cells. Immunity. 2011;34:364-74 pubmed 出版商
Kasler H, Young B, Mottet D, Lim H, Collins A, Olson E, et al. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. J Immunol. 2011;186:4782-93 pubmed 出版商
Birjandi S, Ippolito J, Ramadorai A, Witte P. Alterations in marginal zone macrophages and marginal zone B cells in old mice. J Immunol. 2011;186:3441-51 pubmed 出版商
Kaplan I, Morisot S, Heiser D, Cheng W, Kim M, Civin C. Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence. J Immunol. 2011;186:2826-34 pubmed 出版商
Guarda G, Zenger M, Yazdi A, Schroder K, Ferrero I, Menu P, et al. Differential expression of NLRP3 among hematopoietic cells. J Immunol. 2011;186:2529-34 pubmed 出版商
Ermakova O, Piszczek L, Luciani L, Cavalli F, Ferreira T, Farley D, et al. Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice. EMBO Mol Med. 2011;3:50-66 pubmed 出版商
Zhang Y, Zhou Y, Lou J, Li J, Bo L, Zhu K, et al. PD-L1 blockade improves survival in experimental sepsis by inhibiting lymphocyte apoptosis and reversing monocyte dysfunction. Crit Care. 2010;14:R220 pubmed 出版商
Buhtoiarov I, Sondel P, Wigginton J, Buhtoiarova T, Yanke E, Mahvi D, et al. Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages. Immunology. 2011;132:226-39 pubmed 出版商
Flutter B, Edwards N, Fallah Arani F, Henderson S, Chai J, Sivakumaran S, et al. Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation. J Clin Invest. 2010;120:3855-68 pubmed 出版商
de Bruin A, Buitenhuis M, Van Der Sluijs K, van Gisbergen K, Boon L, Nolte M. Eosinophil differentiation in the bone marrow is inhibited by T cell-derived IFN-gamma. Blood. 2010;116:2559-69 pubmed 出版商
Anthony D, Andrews D, Chow M, Watt S, House C, Akira S, et al. A role for granzyme M in TLR4-driven inflammation and endotoxicosis. J Immunol. 2010;185:1794-803 pubmed 出版商
Colombo M, Sun G, Alugupalli K. T-cell-independent immune responses do not require CXC ligand 13-mediated B1 cell migration. Infect Immun. 2010;78:3950-6 pubmed 出版商
Shriner A, Liu H, Sun G, Guimond M, Alugupalli K. IL-7-dependent B lymphocytes are essential for the anti-polysaccharide response and protective immunity to Streptococcus pneumoniae. J Immunol. 2010;185:525-31 pubmed 出版商
Knickelbein J, Watkins S, McMenamin P, Hendricks R. Stratification of Antigen-presenting Cells within the Normal Cornea. Ophthalmol Eye Dis. 2009;1:45-54 pubmed
Conboy M, Cerletti M, Wagers A, Conboy I. Immuno-analysis and FACS sorting of adult muscle fiber-associated stem/precursor cells. Methods Mol Biol. 2010;621:165-73 pubmed 出版商
Rodriguez Manzanet R, Sanjuan M, Wu H, Quintana F, Xiao S, Anderson A, et al. T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice. Proc Natl Acad Sci U S A. 2010;107:8706-11 pubmed 出版商
Berger M, Krebs P, Crozat K, Li X, Croker B, Siggs O, et al. An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence. Nat Immunol. 2010;11:335-43 pubmed 出版商
Eppert B, Motz G, Wortham B, Flury J, Borchers M. CCR7 deficiency leads to leukocyte activation and increased clearance in response to pulmonary Pseudomonas aeruginosa infection. Infect Immun. 2010;78:2099-107 pubmed 出版商
Larson R, Zimmerli S, Comeau M, Itano A, Omori M, Iseki M, et al. Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses. J Immunol. 2010;184:2974-84 pubmed 出版商
Xie L, Ortega M, Mora S, Chapes S. Interactive changes between macrophages and adipocytes. Clin Vaccine Immunol. 2010;17:651-9 pubmed 出版商
Goodyear A, Jones A, Troyer R, Bielefeldt Ohmann H, Dow S. Critical protective role for MCP-1 in pneumonic Burkholderia mallei infection. J Immunol. 2010;184:1445-54 pubmed 出版商
Xiao X, Zhao P, Rodriguez Pinto D, Qi D, Henegariu O, Alexopoulou L, et al. Inflammatory regulation by TLR3 in acute hepatitis. J Immunol. 2009;183:3712-9 pubmed 出版商
Le Grand F, Jones A, Seale V, Scime A, Rudnicki M. Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells. Cell Stem Cell. 2009;4:535-47 pubmed 出版商
Krivtsov A, Wang Y, Feng Z, Armstrong S. Gene expression profiling of leukemia stem cells. Methods Mol Biol. 2009;538:231-46 pubmed 出版商
Ozao Choy J, Ma G, Kao J, Wang G, Meseck M, Sung M, et al. The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies. Cancer Res. 2009;69:2514-22 pubmed 出版商
Roudaia L, Cheney M, Manuylova E, Chen W, Morrow M, Park S, et al. CBFbeta is critical for AML1-ETO and TEL-AML1 activity. Blood. 2009;113:3070-9 pubmed 出版商
Gongora M, Lob H, Landmesser U, Guzik T, Martin W, Ozumi K, et al. Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air: a potential mechanism underlying adult respiratory distress syndrome. Am J Pathol. 2008;173:915-26 pubmed 出版商
Chen Y, Wang X, Di L, Fu G, Chen Y, Bai L, et al. Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis. J Biol Chem. 2008;283:29593-601 pubmed 出版商
Godek M, Michel R, Chamberlain L, Castner D, Grainger D. Adsorbed serum albumin is permissive to macrophage attachment to perfluorocarbon polymer surfaces in culture. J Biomed Mater Res A. 2009;88:503-19 pubmed 出版商
Cullere X, Lauterbach M, Tsuboi N, Mayadas T. Neutrophil-selective CD18 silencing using RNA interference in vivo. Blood. 2008;111:3591-8 pubmed 出版商
Jerrells T, Pavlik J, Devasure J, Vidlak D, Costello A, Strachota J, et al. Association of chronic alcohol consumption and increased susceptibility to and pathogenic effects of pulmonary infection with respiratory syncytial virus in mice. Alcohol. 2007;41:357-69 pubmed
Lucas M, Schachterle W, Oberle K, Aichele P, Diefenbach A. Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity. 2007;26:503-17 pubmed
Li Y, Brazzell J, Herrera A, Walcheck B. ADAM17 deficiency by mature neutrophils has differential effects on L-selectin shedding. Blood. 2006;108:2275-9 pubmed
Sakamoto H, Dai G, Tsujino K, Hashimoto K, Huang X, Fujimoto T, et al. Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development. Blood. 2006;108:896-903 pubmed
Zhang Y, McCormick L, Desai S, Wu C, Gilliam A. Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation. J Immunol. 2002;168:3088-98 pubmed
Dembic Z, Schenck K, Bogen B. Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4+ T cells. Proc Natl Acad Sci U S A. 2000;97:2697-702 pubmed
Ault K, Springer T. Cross-reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells. J Immunol. 1981;126:359-64 pubmed
Sanchez Madrid F, Simon P, Thompson S, Springer T. Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J Exp Med. 1983;158:586-602 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD11b Monoclonal Antibody (M1/70), APC, eBioscience™
目录# :
17-0112-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.125 µg/test
物种 :
小鼠
克隆 :
M1/70
抗体亚型 :
IgG2b, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.125 µg/test
别名 :
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国