产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD40 Monoclonal Antibody (1C10), APC, eBioscience™
目录 :
17-0401-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
APC
克隆名称 :
1C10
反应物种 :
人类, 小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 96
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 3a
Zhang H, Qi Y, Yuan Y, Cai L, Xu H, Zhang L, et al. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation. Sci Rep. 2017;7:41887 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 2
Schachtner H, Weimershaus M, Stache V, Plewa N, Legler D, Höpken U, et al. Loss of Gadkin Affects Dendritic Cell Migration In Vitro. PLoS ONE. 2015;10:e0143883 pubmed 出版商
  • 流式细胞仪; 人类
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Andersohn A, Garcia M, Fan Y, Thompson M, Akimzhanov A, Abdullahi A, et al. Aggregated and Hyperstable Damage-Associated Molecular Patterns Are Released During ER Stress to Modulate Immune Function. Front Cell Dev Biol. 2019;7:198 pubmed 出版商
Nam J, Son S, Ochyl L, Kuai R, Schwendeman A, Moon J. Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer. Nat Commun. 2018;9:1074 pubmed 出版商
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Pan Y, Yu Y, Lin C, Lanier L, Chu C. Fc?RI ?-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells. Front Immunol. 2017;8:1424 pubmed 出版商
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Collinson Pautz M, Slawin K, Levitt J, Spencer D. MyD88/CD40 Genetic Adjuvant Function in Cutaneous Atypical Antigen-Presenting Cells Contributes to DNA Vaccine Immunogenicity. PLoS ONE. 2016;11:e0164547 pubmed 出版商
Saini A, Mahajan S, Gupta P. Nuclear receptor expression atlas in BMDCs: Nr4a2 restricts immunogenicity of BMDCs and impedes EAE. Eur J Immunol. 2016;46:1842-53 pubmed 出版商
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Wang S, Wu B, Xue J, Wang M, Chen R, Wang B. Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge. Hum Vaccin Immunother. 2014;10:461-8 pubmed 出版商
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van der Merwe M, Abdelsamed H, Seth A, Ong T, Vogel P, Pillai A. Recipient myeloid-derived immunomodulatory cells induce PD-1 ligand-dependent donor CD4+Foxp3+ regulatory T cell proliferation and donor-recipient immune tolerance after murine nonmyeloablative bone marrow transplantation. J Immunol. 2013;191:5764-76 pubmed 出版商
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Tasso R, Ulivi V, Reverberi D, Lo Sicco C, Descalzi F, Cancedda R. In vivo implanted bone marrow-derived mesenchymal stem cells trigger a cascade of cellular events leading to the formation of an ectopic bone regenerative niche. Stem Cells Dev. 2013;22:3178-91 pubmed 出版商
Kayes T, Fang Y, Yu S, Downey E, Wang S, Braley Mullen H. Agonistic anti-CD40 induces thyrocyte proliferation and promotes thyroid autoimmunity by increasing CD40 expression on thyroid epithelial cells. J Immunol. 2013;190:3928-38 pubmed 出版商
Roehrich M, Spicher A, Milano G, Vassalli G. Characterization of cardiac-resident progenitor cells expressing high aldehyde dehydrogenase activity. Biomed Res Int. 2013;2013:503047 pubmed 出版商
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Li G, Smithey M, Rudd B, Nikolich Zugich J. Age-associated alterations in CD8?+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium. Aging Cell. 2012;11:968-77 pubmed 出版商
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Gowda N, Wu X, Gowda D. TLR9 and MyD88 are crucial for the development of protective immunity to malaria. J Immunol. 2012;188:5073-85 pubmed 出版商
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Ribeiro Gomes F, Peters N, Debrabant A, Sacks D. Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-leishmania response. PLoS Pathog. 2012;8:e1002536 pubmed 出版商
Sauma D, Ramirez A, Alvarez K, Rosemblatt M, Bono M. Notch signalling regulates cytokine production by CD8+ and CD4+ T cells. Scand J Immunol. 2012;75:389-400 pubmed 出版商
Rose S, Misharin A, Perlman H. A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytometry A. 2012;81:343-50 pubmed 出版商
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Ferret Bernard S, Castro Borges W, Dowle A, Sanin D, Cook P, Turner J, et al. Plasma membrane proteomes of differentially matured dendritic cells identified by LC-MS/MS combined with iTRAQ labelling. J Proteomics. 2012;75:938-48 pubmed 出版商
Szekeres Z, Herbáth M, Szittner Z, Papp K, Erdei A, Prechl J. Modulation of the humoral immune response by targeting CD40 and Fc?RII/III; delivery of soluble but not particulate antigen to CD40 enhances antibody responses with a Th1 bias. Mol Immunol. 2011;49:155-62 pubmed 出版商
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Gowda N, Wu X, Gowda D. The nucleosome (histone-DNA complex) is the TLR9-specific immunostimulatory component of Plasmodium falciparum that activates DCs. PLoS ONE. 2011;6:e20398 pubmed 出版商
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Buhtoiarov I, Sondel P, Wigginton J, Buhtoiarova T, Yanke E, Mahvi D, et al. Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages. Immunology. 2011;132:226-39 pubmed 出版商
Satpathy S, Shenoy G, Kaw S, Vaidya T, Bal V, Rath S, et al. Inhibition of terminal differentiation of B cells mediated by CD27 and CD40 involves signaling through JNK. J Immunol. 2010;185:6499-507 pubmed 出版商
Wismar R, Brix S, Laerke H, Frøkiaer H. Comparative analysis of a large panel of non-starch polysaccharides reveals structures with selective regulatory properties in dendritic cells. Mol Nutr Food Res. 2011;55:443-54 pubmed 出版商
Giannattasio G, Fujioka D, Xing W, Katz H, Boyce J, Balestrieri B. Group V secretory phospholipase A2 reveals its role in house dust mite-induced allergic pulmonary inflammation by regulation of dendritic cell function. J Immunol. 2010;185:4430-8 pubmed 出版商
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Marchlik E, Thakker P, Carlson T, Jiang Z, Ryan M, Marusic S, et al. Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality. J Leukoc Biol. 2010;88:1171-80 pubmed 出版商
Ait Oufella H, Herbin O, Bouaziz J, Binder C, Uyttenhove C, Laurans L, et al. B cell depletion reduces the development of atherosclerosis in mice. J Exp Med. 2010;207:1579-87 pubmed 出版商
Matsushita H, Ohta S, Shiraishi H, Suzuki S, Arima K, Toda S, et al. Endotoxin tolerance attenuates airway allergic inflammation in model mice by suppression of the T-cell stimulatory effect of dendritic cells. Int Immunol. 2010;22:739-47 pubmed 出版商
Sugita S, Horie S, Yamada Y, Mochizuki M. Inhibition of B-cell activation by retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2010;51:5783-8 pubmed 出版商
Pearson S, Lancrin C, Lacaud G, Kouskoff V. The sequential expression of CD40 and Icam2 defines progressive steps in the formation of blood precursors from the mesoderm germ layer. Stem Cells. 2010;28:1089-98 pubmed 出版商
Vallerskog T, Martens G, Kornfeld H. Diabetic mice display a delayed adaptive immune response to Mycobacterium tuberculosis. J Immunol. 2010;184:6275-82 pubmed 出版商
Hayashi E, Granato A, Paiva L, Bertho A, Bellio M, Nobrega A. TLR4 promotes B cell maturation: independence and cooperation with B lymphocyte-activating factor. J Immunol. 2010;184:4662-72 pubmed 出版商
Hirata Y, Hamanaka S, Onodera M. Transactivation of the dopamine receptor 3 gene by a single provirus integration results in development of B-cell lymphoma in transgenic mice generated from retrovirally transduced embryonic stem cells. Blood. 2010;115:3930-8 pubmed 出版商
Larson R, Zimmerli S, Comeau M, Itano A, Omori M, Iseki M, et al. Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses. J Immunol. 2010;184:2974-84 pubmed 出版商
Jiang Y, Xue X, Chen X, Zhuang W, Sun J, Shen L, et al. Hemozoin from Schistosoma japonicum does not affect murine myeloid dendritic cell function. Parasitol Res. 2010;106:653-9 pubmed 出版商
Toscano M, Delgado M, Kong W, Martin F, Skarica M, Ganea D. Dendritic cells transduced with lentiviral vectors expressing VIP differentiate into VIP-secreting tolerogenic-like DCs. Mol Ther. 2010;18:1035-45 pubmed 出版商
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Farrand K, Dickgreber N, Stoitzner P, Ronchese F, Petersen T, Hermans I. Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigens. J Immunol. 2009;183:7732-42 pubmed 出版商
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Buhtoiarov I, Rakhmilevich A, Lanier L, Ranheim E, Sondel P. Naive mouse macrophages become activated following recognition of L5178Y lymphoma cells via concurrent ligation of CD40, NKG2D, and CD18 molecules. J Immunol. 2009;182:1940-53 pubmed 出版商
Moniz R, Chan A, Kelly K. Identification of dendritic cell subsets responding to genital infection by Chlamydia muridarum. FEMS Immunol Med Microbiol. 2009;55:226-36 pubmed 出版商
Lencioni K, Seamons A, Treuting P, Maggio Price L, Brabb T. Murine norovirus: an intercurrent variable in a mouse model of bacteria-induced inflammatory bowel disease. Comp Med. 2008;58:522-33 pubmed
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Watanabe C, Shu G, Zheng T, Flavell R, Clark E. Caspase 6 regulates B cell activation and differentiation into plasma cells. J Immunol. 2008;181:6810-9 pubmed
Siracusa M, Reece J, Urban J, Scott A. Dynamics of lung macrophage activation in response to helminth infection. J Leukoc Biol. 2008;84:1422-33 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD40 Monoclonal Antibody (1C10), APC, eBioscience™
目录# :
17-0401-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test
物种 :
小鼠
克隆 :
1C10
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
The CD40 antigen is a single chain glycoprotein that is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin's disease associated antigen, CD30. CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of CD40, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of CD40 encoding distinct isoforms have been reported. Diseases associated with CD40 dysfunction include Type 3 Hyper-Igm immunodeficiency and CD40 ligand deficiency.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test
别名 :
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国