产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD83 Monoclonal Antibody (HB15e), APC, eBioscience
目录 :
17-0839-42
规格 :
100试验
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
APC
克隆名称 :
HB15e
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 39
出版应用/物种/样本/稀释 | 参考文献 |
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Yan R, Zhong W, Zhu Y, Zhang X. Trichosanthin-stimulated dendritic cells induce a type 2 helper T lymphocyte response through the OX40 ligand. J Investig Allergol Clin Immunol. 2012;22:491-500 pubmed
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Reske A, Pollara G, Krummenacher C, Katz D, Chain B. Glycoprotein-dependent and TLR2-independent innate immune recognition of herpes simplex virus-1 by dendritic cells. J Immunol. 2008;180:7525-36 pubmed
| |
Metharom P, Velten F, Goerdt S. Highly phagocytic, CD4hi, CD14hi and CD16hi antigen-presenting cells modulated by tumour-conditioned media retain the capacity to mature and induce TH1 T-cell proliferation. Mol Immunol. 2006;43:2070-82 pubmed
| |
Amanuma R, Nakajima T, Yoshie H, Yamazaki K. Increased infiltration of CD1d and natural killer T cells in periodontal disease tissues. J Periodontal Res. 2006;41:73-9 pubmed
| |
Roura Mir C, Wang L, Cheng T, Matsunaga I, Dascher C, Peng S, et al. Mycobacterium tuberculosis regulates CD1 antigen presentation pathways through TLR-2. J Immunol. 2005;175:1758-66 pubmed
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Ashton Chess J, Blancho G. An in vitro evaluation of the potential suitability of peripheral blood CD14(+) and bone marrow CD34(+)-derived dendritic cells for a tolerance inducing regimen in the primate. J Immunol Methods. 2005;297:237-52 pubmed
| |
McCully M, Chau T, Luke P, Blake P, Madrenas J. Characterization of human peritoneal dendritic cell precursors and their involvement in peritonitis. Clin Exp Immunol. 2005;139:513-25 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD83 Monoclonal Antibody (HB15e), APC, eBioscience
目录# :
17-0839-42
规格 :
100试验
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µL (0.5 µg)/test
物种 :
人类
克隆 :
HB15e
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD83 cell surface antigen is a 40-45kD glycoprotein expressed by peripheral blood dendritic cells. Peripheral lymphocytes can be induced to express very low levels of CD83 after culture in agents such as Con A or PHA. In immunohistology, CD83 is shown to be expressed strongly by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centres. CD83 is also expressed by Langerhan's cells in the skin. The CD83 antigen is a 186-amino-acid single-chain glycoprotein and this molecule is a member of the immunoglobulin superfamily that is composed of an extracellular V-type Ig-like single domain, a transmembrane region, and a short, 40-amino-acid cytoplasmic tail. CD83 antigen undergoes extensive post-translational glycosylation, since the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immuno-phenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also co-express T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13, CD33, CD36), cytokine receptors as well as other cell surface molecules. Diseases associated with CD83 dysfunction include plague and Rift Valley Fever.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.5 µg)/test
别名 :
B-cell activation protein; BL11; CD antigen CD83; CD83; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; cell surface protein HB15; cell-surface glycoprotein; HB15; hCD83; mCD83
更多信息或购买 :
公司信息
赛默飞世尔
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