产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
蛋白
产品名称 :
Human IL-5 Recombinant Protein, PeproTech
目录 :
200-05微克
规格 :
50微克
价格 :
美国558.00
更多信息或购买 :
文章摘录数: 31
参考文献 |
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Pazdrak K, Straub C, Maroto R, Stafford S, White W, Calhoun W, et al. Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling. J Immunol. 2016;197:3782-3791 pubmed
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Fernandez R, Maecker H. Cytokine-stimulated Phosphoflow of PBMC Using CyTOF Mass Cytometry. Bio Protoc. 2015;5: pubmed
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Sturm E, Schratl P, Schuligoi R, Konya V, Sturm G, Lippe I, et al. Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors. J Immunol. 2008;181:7273-83 pubmed
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Sakuishi K, Oki S, Araki M, Porcelli S, Miyake S, Yamamura T. Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation. J Immunol. 2007;179:3452-62 pubmed
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Munitz A, Bachelet I, Eliashar R, Moretta A, Moretta L, Levi Schaffer F. The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils. Blood. 2006;107:1996-2003 pubmed
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van Beek J, van Meurs M, t Hart B, Brok H, Neal J, Chatagner A, et al. Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation. J Immunol. 2005;174:2353-65 pubmed
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Ferland C, Flamand N, Davoine F, Chakir J, Laviolette M. IL-16 activates plasminogen-plasmin system and promotes human eosinophil migration into extracellular matrix via CCR3-chemokine-mediated signaling and by modulating CD4 eosinophil expression. J Immunol. 2004;173:4417-24 pubmed
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Hemminki A, Kanerva A, Liu B, Wang M, Alvarez R, Siegal G, et al. Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression. Cancer Res. 2003;63:847-53 pubmed
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产品信息
产品类型 :
蛋白
产品名称 :
Human IL-5 Recombinant Protein, PeproTech
目录# :
200-05微克
规格 :
50微克
价格 :
美国558.00
克隆性 :
重组
纯度 :
HPLC, 十二烷基磺酸钠-PAGE
反应物种 :
人类
应用 :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
物种 :
人类
储存 :
-20°C
描述 :
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
格式 :
冻干
应用w/稀释 :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
别名 :
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF
更多信息或购买 :
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赛默飞世尔
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