产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
蛋白
产品名称 :
Human IL-6 Recombinant Protein, PeproTech
目录 :
200-06微克
规格 :
100微克
价格 :
美国648.00
更多信息或购买 :
文章摘录数: 645
参考文献
Cruz Lorenzo E, Ramirez N, Lee J, Pandhe S, Wang L, Hernandez Doria J, et al. Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity. Viruses. 2022;14: pubmed 出版商
Zuniga M, Gomes C, Chen Z, Martinez C, Devlin J, Loke P, et al. Plasmodium falciparum and TNF-α Differentially Regulate Inflammatory and Barrier Integrity Pathways in Human Brain Endothelial Cells. MBio. 2022;13:e0174622 pubmed 出版商
Igarashi N, Miyata K, Loo T, Chiba M, Hanyu A, Nishio M, et al. Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells. Nat Commun. 2022;13:4157 pubmed 出版商
Hug N, Aitken S, Longman D, Raab M, Armes H, Mann A, et al. A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation. RNA. 2022;28:1224-1238 pubmed 出版商
Dannenmann B, Skokowa J. Generation, expansion, and drug treatment of hematopoietic progenitor cells derived from human iPSCs. STAR Protoc. 2022;3:101400 pubmed 出版商
Canals Hernaez D, Hughes M, Li Y, Mainero Rocca I, Dean P, Brassard J, et al. Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models. Front Oncol. 2022;12:856424 pubmed 出版商
Wang B, Wang C, Wan Y, Gao J, Ma Y, Zhang Y, et al. Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq. Cell Discov. 2022;8:41 pubmed 出版商
Nystrom S, Li G, Datta S, Soldano K, Silas D, Weins A, et al. JAK inhibitor blocks COVID-19 cytokine-induced JAK/STAT/APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids. JCI Insight. 2022;7: pubmed 出版商
Gil Del Alcazar C, Trinh A, Aleckovic M, Rojas Jimenez E, Harper N, Oliphant M, et al. Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer. Cancer Immunol Res. 2022;10:680-697 pubmed 出版商
Yu Z, Wei X, Liu L, Sun H, Fang T, Wang L, et al. Indirubin-3'-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma. EBioMedicine. 2022;78:103950 pubmed 出版商
Wang Q, Chen Y, Xie Y, Yang D, Sun Y, Yuan Y, et al. Histone H1.2 promotes hepatocarcinogenesis by regulating signal transducer and activator of transcription 3 signaling. Cancer Sci. 2022;113:1679-1692 pubmed 出版商
Wang H, Xie L, Song X, Wang J, Li X, Lin Z, et al. Purine-Induced IFN-γ Promotes Uric Acid Production by Upregulating Xanthine Oxidoreductase Expression. Front Immunol. 2022;13:773001 pubmed 出版商
Niehues H, Rikken G, van Vlijmen Willems I, Rodijk Olthuis D, van Erp P, Zeeuwen P, et al. Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis. JID Innov. 2022;2:100066 pubmed 出版商
Wang Y, Huo T, Tseng Y, Dang L, Yu Z, Yu W, et al. Using Cryo-ET to distinguish platelets during pre-acute myeloid leukemia from steady state hematopoiesis. Commun Biol. 2022;5:72 pubmed 出版商
Al Haq A, Tseng H, Chen L, Wang C, Hsu H. Targeting prooxidant MnSOD effect inhibits triple-negative breast cancer (TNBC) progression and M2 macrophage functions under the oncogenic stress. Cell Death Dis. 2022;13:49 pubmed 出版商
Karpf L, Trichot C, Faucheux L, Legbre I, Grandclaudon M, Lahoute C, et al. A multivariate modeling framework to quantify immune checkpoint context-dependent stimulation on T cells. Cell Discov. 2022;8:1 pubmed 出版商
Oburoglu L, Mansell E, Canals I, Sigurdsson V, Guibentif C, Soneji S, et al. Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence. EMBO Rep. 2022;23:e54384 pubmed 出版商
He Y, Gallman A, Xie C, Shen Q, Ma J, Wolfreys F, et al. P2RY8 variants in lupus patients uncover a role for the receptor in immunological tolerance. J Exp Med. 2022;219: pubmed 出版商
Schneider M, Emmenegger M, Xu C, Condado Morales I, Meisl G, Turelli P, et al. Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma. Life Sci Alliance. 2022;5: pubmed 出版商
Stavast C, van Zuijen I, Karkoulia E, xd6 z xe7 elik A, Van Hoven Beijen A, Leon L, et al. The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis. Leukemia. 2022;36:687-700 pubmed 出版商
Texler B, Zollner A, Reinstadler V, Reider S, Macheiner S, Jelušić B, et al. Tofacitinib-Induced Modulation of Intestinal Adaptive and Innate Immunity and Factors Driving Cellular and Systemic Pharmacokinetics. Cell Mol Gastroenterol Hepatol. 2022;13:383-404 pubmed 出版商
Zhong B, Cheng B, Huang X, Xiao Q, Niu Z, Chen Y, et al. Colorectal cancer-associated fibroblasts promote metastasis by up-regulating LRG1 through stromal IL-6/STAT3 signaling. Cell Death Dis. 2021;13:16 pubmed 出版商
Jugler C, Sun H, Chen Q. SARS-CoV-2 Spike Protein-Induced Interleukin 6 Signaling Is Blocked by a Plant-Produced Anti-Interleukin 6 Receptor Monoclonal Antibody. Vaccines (Basel). 2021;9: pubmed 出版商
Georgolopoulos G, Psatha N, Iwata M, Nishida A, Som T, Yiangou M, et al. Discrete regulatory modules instruct hematopoietic lineage commitment and differentiation. Nat Commun. 2021;12:6790 pubmed 出版商
Tao P, Wang S, Ozen S, Lee P, Zhang J, Wang J, et al. Deubiquitination of proteasome subunits by OTULIN regulates type I IFN production. Sci Adv. 2021;7:eabi6794 pubmed 出版商
Tsui M, Min W, Ng S, Dobbs K, Notarangelo L, Dror Y, et al. The Use of Induced Pluripotent Stem Cells to Study the Effects of Adenosine Deaminase Deficiency on Human Neutrophil Development. Front Immunol. 2021;12:748519 pubmed 出版商
Rink S, Kaiser B, Steiner M, Duerkop A, Baeumner A. Highly sensitive interleukin 6 detection by employing commercially ready liposomes in an LFA format. Anal Bioanal Chem. 2021;: pubmed 出版商
Bent E, Mill xe1 n Barea L, Zhuang I, Goulet D, Fr xf6 se J, Hemann M. Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy. Nat Commun. 2021;12:6218 pubmed 出版商
Rodr xed guez A, Filiatrault J, Flores Guzm xe1 n P, Mayani H, Parmar K, D Andrea A. Isolation of human and murine hematopoietic stem cells for DNA damage and DNA repair assays. STAR Protoc. 2021;2:100846 pubmed 出版商
Chruewkamlow N, Pruekprasert K, Phutthakunphithak P, Acharayothin O, Prapassaro T, Hongku K, et al. Novel culture media enhances mononuclear cells from patients with chronic limb-threatening ischemia to increase vasculogenesis and anti-inflammatory effect. Stem Cell Res Ther. 2021;12:520 pubmed 出版商
Gerosa R, Boettcher S, Kovtonyuk L, Hausmann A, Hardt W, Hidalgo J, et al. CXCL12-abundant reticular cells are the major source of IL-6 upon LPS stimulation and thereby regulate hematopoiesis. Blood Adv. 2021;5:5002-5015 pubmed 出版商
Yun H, Narayan N, Vohra S, Giotopoulos G, Mupo A, Madrigal P, et al. Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression. Nat Genet. 2021;53:1443-1455 pubmed 出版商
Qin L, Cao X, Kaneko T, Voss C, Liu X, Wang G, et al. Dynamic interplay of two molecular switches enabled by the MEK1/2-ERK1/2 and IL-6-STAT3 signaling axes controls epithelial cell migration in response to growth factors. J Biol Chem. 2021;297:101161 pubmed 出版商
Stackowicz J, Gaudenzio N, Serhan N, Conde E, Godon O, Marichal T, et al. Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome. J Exp Med. 2021;218: pubmed 出版商
Pelka K, Hofree M, Chen J, Sarkizova S, Pirl J, Jorgji V, et al. Spatially organized multicellular immune hubs in human colorectal cancer. Cell. 2021;184:4734-4752.e20 pubmed 出版商
Estrada A, Rodriguez A, Rodriguez G, Grant A, Ayala Marín Y, Arrieta A, et al. Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction. Sci Rep. 2021;11:16951 pubmed 出版商
Boutin J, Rosier J, Cappellen D, Prat F, Toutain J, Pennamen P, et al. CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells. Nat Commun. 2021;12:4922 pubmed 出版商
Jankowski J, Lee H, Wilflingseder J, Hennighausen L. JAK inhibitors dampen activation of interferon-activated transcriptomes and the SARS-CoV-2 receptor ACE2 in human renal proximal tubules. iScience. 2021;24:102928 pubmed 出版商
Kim H, Kim J, Seol B, Song C, Jeong J, Cho Y. Directly reprogrammed natural killer cells for cancer immunotherapy. Nat Biomed Eng. 2021;5:1360-1376 pubmed 出版商
Su H, Jiang M, Senevirathne C, Aluri S, Zhang T, Guo H, et al. Methylation of dual-specificity phosphatase 4 controls cell differentiation. Cell Rep. 2021;36:109421 pubmed 出版商
Biavasco R, Lettera E, Giannetti K, Gilioli D, Beretta S, Conti A, et al. Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis. Nat Commun. 2021;12:4559 pubmed 出版商
Malireddi R, Karki R, Sundaram B, Kancharana B, Lee S, Samir P, et al. Inflammatory Cell Death, PANoptosis, Mediated by Cytokines in Diverse Cancer Lineages Inhibits Tumor Growth. Immunohorizons. 2021;5:568-580 pubmed 出版商
Tien P, Lin C, Chen C, Chang C, Ku H, Gan D, et al. Diacerein Inhibits Myopia Progression through Lowering Inflammation in Retinal Pigment Epithelial Cell. Mediators Inflamm. 2021;2021:6660640 pubmed 出版商
Steinberg D, Repudi S, Saleem A, Kustanovich I, Viukov S, Abudiab B, et al. Modeling genetic epileptic encephalopathies using brain organoids. EMBO Mol Med. 2021;13:e13610 pubmed 出版商
Ogishi M, Yang R, Aytekin C, Langlais D, Bourgey M, Khan T, et al. Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child. Nat Med. 2021;: pubmed 出版商
Lee Y, Park E, Park J, Jung K, Lee E. Proinflammatory Features of Stem Cell-like Memory T Cells from Human Patients with Rheumatoid Arthritis. J Immunol. 2021;207:381-388 pubmed 出版商
Yang S, He X, Zhao J, Wang D, Guo S, Gao T, et al. Mitochondrial transcription factor A plays opposite roles in the initiation and progression of colitis-associated cancer. Cancer Commun (Lond). 2021;41:695-714 pubmed 出版商
Zee B, Poels K, Yao C, Kawabata K, Wu G, Duy C, et al. Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia. iScience. 2021;24:102651 pubmed 出版商
Reyes M, Filbin M, Bhattacharyya R, Sonny A, Mehta A, Billman K, et al. Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro. Sci Transl Med. 2021;13: pubmed 出版商
Bhardwaj R, Kumar L, Chhabra D, Mehra N, Sharma A, Mohanty S, et al. In vitro expansion of fetal liver hematopoietic stem cells. Sci Rep. 2021;11:11879 pubmed 出版商
Di Marcantonio D, Martinez E, Kanefsky J, Huhn J, Gabbasov R, Gupta A, et al. ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia. Mol Cell. 2021;81:2752-2764.e6 pubmed 出版商
Lee H, Jung O, Hennighausen L. JAK inhibitors dampen activation of interferon-stimulated transcription of ACE2 isoforms in human airway epithelial cells. Commun Biol. 2021;4:654 pubmed 出版商
Cheng Y, Xie W, Pickering B, Chu K, Savino A, Yang X, et al. N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation. Cancer Cell. 2021;39:958-972.e8 pubmed 出版商
Amit I, Iancu O, Levy Jurgenson A, Kurgan G, McNeill M, Rettig G, et al. CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data. Nat Commun. 2021;12:3042 pubmed 出版商
Cai C, Gu S, Yu Y, Zhu Y, Zhang H, Yuan B, et al. PRMT5 Enables Robust STAT3 Activation via Arginine Symmetric Dimethylation of SMAD7. Adv Sci (Weinh). 2021;8:2003047 pubmed 出版商
Renner K, Schwittay T, Chaabane S, Gottschling J, Muller C, Tiefenböck C, et al. Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes. Nat Commun. 2021;12:3006 pubmed 出版商
Li M, Yan Y, Zhang X, Zhang Y, Xu X, Zhang L, et al. Scaffold compound L971 exhibits anti-inflammatory activities through inhibition of JAK/STAT and NFκB signalling pathways. J Cell Mol Med. 2021;: pubmed 出版商
Mills R, Humphrey S, Fortuna P, Lor M, Foster S, Quaife Ryan G, et al. BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection. Cell. 2021;184:2167-2182.e22 pubmed 出版商
Cunningham S, Hackstein H. Rapid generation of monocyte-derived antigen-presenting cells with dendritic cell-like properties. Transfusion. 2021;61:1845-1855 pubmed 出版商
Ueno T, Yamamoto Y, Kawasaki K. Phagocytosis of microparticles increases responsiveness of macrophage-like cell lines U937 and THP-1 to bacterial lipopolysaccharide and lipopeptide. Sci Rep. 2021;11:6782 pubmed 出版商
Thomas M, Abdelhamed S, Hiltenbrand R, Schwartz J, Sakurada S, Walsh M, et al. Pediatric MDS and bone marrow failure-associated germline mutations in SAMD9 and SAMD9L impair multiple pathways in primary hematopoietic cells. Leukemia. 2021;35:3232-3244 pubmed 出版商
Mishima S, Kashiwakura J, Toyoshima S, Sasaki Sakamoto T, Sano Y, Nakanishi K, et al. Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis. Sci Rep. 2021;11:5738 pubmed 出版商
Stahlhut M, Ha T, Takmakova E, Morgan M, Schwarzer A, Schaudien D, et al. Conditionally immortalised leukaemia initiating cells co-expressing Hoxa9/Meis1 demonstrate microenvironmental adaptation properties ex vivo while maintaining myelomonocytic memory. Sci Rep. 2021;11:5294 pubmed 出版商
Velten L, Story B, Hern xe1 ndez Malmierca P, Raffel S, Leonce D, Milbank J, et al. Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics. Nat Commun. 2021;12:1366 pubmed 出版商
Van Egeren D, Escabi J, Nguyen M, Liu S, Reilly C, Patel S, et al. Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms. Cell Stem Cell. 2021;28:514-523.e9 pubmed 出版商
Xie B, Khoyratty T, Abu Shah E, F Cespedes P, MacLean A, Pirgova G, et al. The Zinc Finger Protein Zbtb18 Represses Expression of Class I Phosphatidylinositol 3-Kinase Subunits and Inhibits Plasma Cell Differentiation. J Immunol. 2021;206:1515-1527 pubmed 出版商
Tanaka R, Ito Hirano R, Fujimura S, Arita K, Hagiwara H, Mita T, et al. Ex vivo conditioning of peripheral blood mononuclear cells of diabetic patients promotes vasculogenic wound healing. Stem Cells Transl Med. 2021;10:895-909 pubmed 出版商
Zhou B, Qin Y, Zhou J, Ruan J, Xiong F, Dong J, et al. Bortezomib suppresses self-renewal and leukemogenesis of leukemia stem cell by NF-ĸB-dependent inhibition of CDK6 in MLL-rearranged myeloid leukemia. J Cell Mol Med. 2021;25:3124-3135 pubmed 出版商
Jung H, Uenishi G, Park M, Liu P, Suknuntha K, Raymond M, et al. SOX17 integrates HOXA and arterial programs in hemogenic endothelium to drive definitive lympho-myeloid hematopoiesis. Cell Rep. 2021;34:108758 pubmed 出版商
Chen Y, Liu Y, Wu J, Li C, Tang M, Bai L, et al. A two-herb formula inhibits hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes. Sci Rep. 2021;11:3850 pubmed 出版商
Simkin D, Marshall K, Vanoye C, Desai R, Bustos B, Piyevsky B, et al. Dyshomeostatic modulation of Ca2+-activated K+ channels in a human neuronal model of KCNQ2 encephalopathy. elife. 2021;10: pubmed 出版商
Zhu X, Sun Q, Tan W, Cai H. Reducing TGF-β1 cooperated with StemRegenin 1 promoted the expansion ex vivo of cord blood CD34+ cells by inhibiting AhR signalling. Cell Prolif. 2021;54:e12999 pubmed 出版商
Dahl M, Smith E, Warsi S, Rothe M, Ferraz M, Aerts J, et al. Correction of pathology in mice displaying Gaucher disease type 1 by a clinically-applicable lentiviral vector. Mol Ther Methods Clin Dev. 2021;20:312-323 pubmed 出版商
Tang H, Fang H, Guo W, Cao S, Guo D, Zhang H, et al. Single nucleotide polymorphisms in interleukin-6 attenuates hepatocytes injury in hypoxia/re-oxygenation via STAT3 signal pathway mediated autophagy. Mol Biol Rep. 2021;48:1687-1695 pubmed 出版商
Vavassori V, Mercuri E, Marcovecchio G, Castiello M, Schiroli G, Albano L, et al. Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome. EMBO Mol Med. 2021;13:e13545 pubmed 出版商
Sharma R, Dever D, Lee C, Azizi A, Pan Y, Camarena J, et al. The TRACE-Seq method tracks recombination alleles and identifies clonal reconstitution dynamics of gene targeted human hematopoietic stem cells. Nat Commun. 2021;12:472 pubmed 出版商
Zhang W, Yin G, Zhao H, Ling H, Xie Z, Xiao C, et al. Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner. Cell Death Dis. 2021;12:102 pubmed 出版商
Wang Y, Mohseni M, Grauel A, Diez J, Guan W, Liang S, et al. SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms. Sci Rep. 2021;11:1399 pubmed 出版商
Louka E, Povinelli B, Rodriguez Meira A, Buck G, Wen W, Wang G, et al. Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia. J Exp Med. 2021;218: pubmed 出版商
Vecellio M, Chen L, Cohen C, Cortes A, Li Y, Bonham S, et al. Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis. Arthritis Rheumatol. 2021;73:980-990 pubmed 出版商
Almeida L, Dhillon LaBrooy A, Castro C, Adossa N, Carriche G, Guderian M, et al. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis. Immunity. 2021;54:68-83.e6 pubmed 出版商
Rodriguez A, Zhang K, Färkkilä A, Filiatrault J, Yang C, Velázquez M, et al. MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia. Cell Stem Cell. 2021;28:33-47.e8 pubmed 出版商
Masalha M, Gur Wahnon D, Meningher T, Ben Dov I, Kassem R, Sidi Y, et al. IL6R is a target of miR-197 in human keratinocytes. Exp Dermatol. 2021;30:1177-1186 pubmed 出版商
Liu F, Pishesha N, Poon Z, Kaushik T, Van Vliet K. Material Viscoelastic Properties Modulate the Mesenchymal Stem Cell Secretome for Applications in Hematopoietic Recovery. ACS Biomater Sci Eng. 2017;3:3292-3306 pubmed 出版商
Tremblay C, Chiu S, Saw J, McCalmont H, Litalien V, Boyle J, et al. Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells. Nat Commun. 2020;11:6211 pubmed 出版商
Luo B, Zhan Y, Luo M, Dong H, Liu J, Lin Y, et al. Engineering of α-PD-1 antibody-expressing long-lived plasma cells by CRISPR/Cas9-mediated targeted gene integration. Cell Death Dis. 2020;11:973 pubmed 出版商
Liang Y, Liang L, Liu Z, Wang Y, Dong X, Qu L, et al. Inhibition of IRE1/JNK pathway in HK-2 cells subjected to hypoxia-reoxygenation attenuates mesangial cells-derived extracellular matrix production. J Cell Mol Med. 2020;24:13408-13420 pubmed 出版商
Guan X, Wang L, Wang H, Wang H, Dai W, Jiang Y. Good Manufacturing Practice-Grade of Megakaryocytes Produced by a Novel Ex Vivo Culturing Platform. Clin Transl Sci. 2020;13:1115-1126 pubmed 出版商
Crosse E, Gordon Keylock S, Rybtsov S, Binagui Casas A, Felchle H, Nnadi N, et al. Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development. Cell Stem Cell. 2020;27:822-839.e8 pubmed 出版商
Palikuqi B, Nguyen D, Li G, Schreiner R, Pellegata A, Liu Y, et al. Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis. Nature. 2020;585:426-432 pubmed 出版商
Evans R, Antonelou M, Sathiananthamoorthy S, Rega M, Henderson S, Ceron Gutierrez L, et al. Inherited salt-losing tubulopathies are associated with immunodeficiency due to impaired IL-17 responses. Nat Commun. 2020;11:4368 pubmed 出版商
Xia X, Cao G, Sun G, Zhu L, Tian Y, Song Y, et al. GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis. J Clin Invest. 2020;130:5180-5196 pubmed 出版商
Aki A, Tanaka K, Nagaoka N, Kimura T, Baba D, Onodera Y, et al. Anti-ORAI1 antibody DS-2741a, a specific CRAC channel blocker, shows ideal therapeutic profiles for allergic disease via suppression of aberrant T-cell and mast cell activation. FASEB Bioadv. 2020;2:478-488 pubmed 出版商
Frame J, Kubaczka C, Long T, Esain V, Soto R, Hachimi M, et al. Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Dev Cell. 2020;: pubmed 出版商
Wang T, Medynets M, Johnson K, Doucet O Hare T, DiSanza B, Li W, et al. Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway. Proc Natl Acad Sci U S A. 2020;117:17842-17853 pubmed 出版商
Yan P, Liu Z, Song M, Wu Z, Xu W, Li K, et al. Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming. Cell Rep. 2020;32:107870 pubmed 出版商
Li X, Ma X, Chen Y, Peng D, Wang H, Chen S, et al. Coinhibition of activated p38 MAPKα and mTORC1 potentiates stemness maintenance of HSCs from SR1-expanded human cord blood CD34+ cells via inhibition of senescence. Stem Cells Transl Med. 2020;9:1604-1616 pubmed 出版商
Scheller L, Schmollack M, Bertschi A, Mansouri M, Saxena P, Fussenegger M. Phosphoregulated orthogonal signal transduction in mammalian cells. Nat Commun. 2020;11:3085 pubmed 出版商
Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, et al. Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion. Cancer Cell. 2020;38:79-96.e11 pubmed 出版商
Lafleur M, Werner J, Fort M, Lobenhofer E, Balazs M, Goyos A. MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities. J Immunotoxicol. 2020;17:110-121 pubmed 出版商
Shapiro J, Iancu O, Jacobi A, McNeill M, Turk R, Rettig G, et al. Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System. Mol Ther Methods Clin Dev. 2020;17:1097-1107 pubmed 出版商
Blanco Melo D, Nilsson Payant B, Liu W, Uhl S, Hoagland D, Møller R, et al. Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19. Cell. 2020;181:1036-1045.e9 pubmed 出版商
Shen C, Sheng Y, Zhu A, Robinson S, Jiang X, Dong L, et al. RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia. Cell Stem Cell. 2020;27:64-80.e9 pubmed 出版商
Belling J, Heidenreich L, Tian Z, Mendoza A, Chiou T, Gong Y, et al. Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells. Proc Natl Acad Sci U S A. 2020;117:10976-10982 pubmed 出版商
Barbier V, Erbani J, Fiveash C, Davies J, Tay J, Tallack M, et al. Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance. Nat Commun. 2020;11:2042 pubmed 出版商
Di Genua C, Valletta S, Buono M, Stoilova B, Sweeney C, Rodriguez Meira A, et al. C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor. Cancer Cell. 2020;37:690-704.e8 pubmed 出版商
Oberhuber M, Pecoraro M, Rusz M, Oberhuber G, Wieselberg M, Haslinger P, et al. STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer. Mol Syst Biol. 2020;16:e9247 pubmed 出版商
Shang D, Sun D, Shi C, Xu J, Shen M, Hu X, et al. Activation of epidermal growth factor receptor signaling mediates cellular senescence induced by certain pro-inflammatory cytokines. Aging Cell. 2020;19:e13145 pubmed 出版商
Lin K, Rutter J, Xie A, Pardieu B, Winn E, Bello R, et al. Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer. Nat Genet. 2020;52:408-417 pubmed 出版商
Wang Z, Zhao M, Yin J, Liu L, Hu L, Huang Y, et al. E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases. J Clin Invest. 2020;130:3717-3733 pubmed 出版商
Shi W, Ma H, Liu T, Yan D, Luo P, Zhai M, et al. Inhibition of Interleukin-6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice. J Cell Mol Med. 2020;24:4748-4761 pubmed 出版商
Shin J, Abaci H, Herron L, Guo Z, Sallee B, Pappalardo A, et al. Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing. Sci Rep. 2020;10:4123 pubmed 出版商
Cribbs A, Terlecki Zaniewicz S, Philpott M, Baardman J, Ahern D, Lindow M, et al. Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism. Proc Natl Acad Sci U S A. 2020;117:6056-6066 pubmed 出版商
Redondo Monte E, Wilding A, Leubolt G, Kerbs P, Bagnoli J, Hartmann L, et al. ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells. Oncogene. 2020;39:3195-3205 pubmed 出版商
Hansen M. Interleukin-6 signaling requires only few IL-6 molecules: Relation to physiological concentrations of extracellular IL-6. Immun Inflamm Dis. 2020;8:170-180 pubmed 出版商
Niederkorn M, Hueneman K, Choi K, Varney M, Romano L, Pujato M, et al. TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis. Cell Rep. 2020;30:2776-2790.e6 pubmed 出版商
Wang X, Shao X, Gu L, Jiang K, Wang S, Chen J, et al. Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells. J Cell Mol Med. 2020;24:4286-4297 pubmed 出版商
Alshetaiwi H, Pervolarakis N, McIntyre L, Ma D, Nguyen Q, Rath J, et al. Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics. Sci Immunol. 2020;5: pubmed 出版商
Schreurs O, Karatsaidis A, Balta M, Grung B, Hals E, Schenck K. Expression of keratins 8, 18, and 19 in epithelia of atrophic oral lichen planus. Eur J Oral Sci. 2020;128:7-17 pubmed 出版商
Panda S, Wigerblad G, Jiang L, Jiménez Andrade Y, Iyer V, Shen Y, et al. IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints. Proc Natl Acad Sci U S A. 2020;117:3103-3113 pubmed 出版商
Chiu C, Wang B, Yu Y, Shyu K. Hyperbaric oxygen activates visfatin expression and angiogenesis via angiotensin II and JNK pathway in hypoxic human coronary artery endothelial cells. J Cell Mol Med. 2020;24:2434-2443 pubmed 出版商
Themeli M, Chhatta A, Boersma H, Prins H, Cordes M, de Wilt E, et al. iPSC-Based Modeling of RAG2 Severe Combined Immunodeficiency Reveals Multiple T Cell Developmental Arrests. Stem Cell Reports. 2020;14:300-311 pubmed 出版商
Okuyama Y, Nagashima H, Ushio Fukai M, Croft M, Ishii N, So T. IQGAP1 restrains T-cell cosignaling mediated by OX40. FASEB J. 2020;34:540-554 pubmed 出版商
Suzuki T, Sato Y, Sano K, Arashiro T, Katano H, Nakajima N, et al. Severe fever with thrombocytopenia syndrome virus targets B cells in lethal human infections. J Clin Invest. 2020;130:799-812 pubmed 出版商
Huang C, Hedl M, Ranjan K, Abraham C. LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These Outcomes. Cell Rep. 2019;29:4525-4539.e4 pubmed 出版商
Yang Y, Liu P, Li D, Yang Q, Li B, Jiang X. Stat-3 signaling promotes cell proliferation and metastasis of gastric cancer through PDCD4 downregulation. Kaohsiung J Med Sci. 2020;36:244-249 pubmed 出版商
Le Floc h A, Allinne J, Nagashima K, Scott G, Birchard D, Asrat S, et al. Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation. Allergy. 2020;75:1188-1204 pubmed 出版商
Wang Y, Lu T, Sun G, Zheng Y, Yang S, Zhang H, et al. Targeting of apoptosis gene loci by reprogramming factors leads to selective eradication of leukemia cells. Nat Commun. 2019;10:5594 pubmed 出版商
Papaioannou D, Petri A, Dovey O, Terreri S, Wang E, Collins F, et al. The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia. Nat Commun. 2019;10:5351 pubmed 出版商
Luo Z, Su R, Wang W, Liang Y, Zeng X, Shereen M, et al. EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production. PLoS Pathog. 2019;15:e1008142 pubmed 出版商
Tarumoto Y, Lin S, Wang J, Milazzo J, Xu Y, Lu B, et al. Salt-Inducible Kinase inhibition suppresses acute myeloid leukemia progression in vivo. Blood. 2019;: pubmed 出版商
Cunha P, Vern Y, Gitton C, Germon P, Foucras G, Rainard P. Expansion, isolation and first characterization of bovine Th17 lymphocytes. Sci Rep. 2019;9:16115 pubmed 出版商
Zhang R, Liu Q, Peng J, Wang M, Gao X, Liao Q, et al. Pancreatic cancer-educated macrophages protect cancer cells from complement-dependent cytotoxicity by up-regulation of CD59. Cell Death Dis. 2019;10:836 pubmed 出版商
White C, Jayasekara W, Picard D, Chen J, Watkins D, Cain J, et al. A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma. Cancers (Basel). 2019;11: pubmed 出版商
Jia C, Keasey M, Malone H, Lovins C, Hagg T. Vitronectin mitigates stroke-increased neurogenesis only in female mice and through FAK-regulated IL-6. Exp Neurol. 2020;323:113088 pubmed 出版商
Sharon D, Cathelin S, Mirali S, Di Trani J, Yanofsky D, Keon K, et al. Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response. Sci Transl Med. 2019;11: pubmed 出版商
Zeng Y, Liu C, Gong Y, Bai Z, Hou S, He J, et al. Single-Cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos. Immunity. 2019;51:930-948.e6 pubmed 出版商
Grandclaudon M, Perrot Dockès M, Trichot C, Karpf L, Abouzid O, Chauvin C, et al. A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication. Cell. 2019;179:432-447.e21 pubmed 出版商
Zhong B, Shi D, Wu F, Wang S, Hu H, Cheng C, et al. Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma. Cell Death Dis. 2019;10:687 pubmed 出版商
Ko J, Mills T, Huang J, Chen N, Mertens T, Collum S, et al. Transforming growth factor β1 alters the 3'-UTR of mRNA to promote lung fibrosis. J Biol Chem. 2019;294:15781-15794 pubmed 出版商
Magoro T, Dandekar A, Jennelle L, Bajaj R, Lipkowitz G, Angelucci A, et al. IL-1β/TNF-α/IL-6 inflammatory cytokines promote STAT1-dependent induction of CH25H in Zika virus-infected human macrophages. J Biol Chem. 2019;294:14591-14602 pubmed 出版商
Martin G, Roy N, Chakraborty S, Desrichard A, Chung S, Woolthuis C, et al. CD97 is a critical regulator of acute myeloid leukemia stem cell function. J Exp Med. 2019;216:2362-2377 pubmed 出版商
Laudisi F, Cherubini F, Di Grazia A, Dinallo V, Di Fusco D, Franzè E, et al. Progranulin sustains STAT3 hyper-activation and oncogenic function in colorectal cancer cells. Mol Oncol. 2019;13:2142-2159 pubmed 出版商
Shan J, Shen J, Wu M, Zhou H, Feng J, Yao C, et al. Tcf7l1 Acts as a Suppressor for the Self-Renewal of Liver Cancer Stem Cells and Is Regulated by IGF/MEK/ERK Signaling Independent of β-Catenin. Stem Cells. 2019;37:1389-1400 pubmed 出版商
Chan L, Li C, Xia W, Hsu J, Lee H, Cha J, et al. IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion. J Clin Invest. 2019;129:3324-3338 pubmed 出版商
Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, et al. Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Cancer Cell. 2019;36:123-138.e10 pubmed 出版商
Dupont L, Du L, Poulter M, Choi S, McIntosh M, Reeves M. Src family kinase activity drives cytomegalovirus reactivation by recruiting MOZ histone acetyltransferase activity to the viral promoter. J Biol Chem. 2019;294:12901-12910 pubmed 出版商
Hu T, Morita K, Hill M, Jiang Y, Kitano A, Saito Y, et al. PRDM16s transforms megakaryocyte-erythroid progenitors into myeloid leukemia-initiating cells. Blood. 2019;134:614-625 pubmed 出版商
Spencer S, Kostel Bal S, Egner W, Lango Allen H, Raza S, Ma C, et al. Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses. J Exp Med. 2019;: pubmed 出版商
Martínez García J, Martinez Banaclocha H, Angosto Bazarra D, de Torre Minguela C, Baroja Mazo A, Alarcon Vila C, et al. P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis. Nat Commun. 2019;10:2711 pubmed 出版商
Mintz M, Felce J, Chou M, Mayya V, Xu Y, Shui J, et al. The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis. Immunity. 2019;: pubmed 出版商
Dimou P, Wright R, Budge K, Midgley A, Satchell S, Peak M, et al. The human glomerular endothelial cells are potent pro-inflammatory contributors in an in vitro model of lupus nephritis. Sci Rep. 2019;9:8348 pubmed 出版商
Pereira B, Devine O, Vukmanovic Stejic M, Chambers E, Subramanian P, Patel N, et al. Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition. Nat Commun. 2019;10:2387 pubmed 出版商
Pellin D, Loperfido M, Baricordi C, Wolock S, Montepeloso A, Weinberg O, et al. A comprehensive single cell transcriptional landscape of human hematopoietic progenitors. Nat Commun. 2019;10:2395 pubmed 出版商
Sheng Y, Ji Z, Zhao H, Wang J, Cheng C, Xu W, et al. Downregulation of the histone methyltransferase SETD2 promotes imatinib resistance in chronic myeloid leukaemia cells. Cell Prolif. 2019;:e12611 pubmed 出版商
Hsu J, Reilly A, Hayes B, Clough C, Konnick E, Torok Storb B, et al. Reprogramming identifies functionally distinct stages of clonal evolution in myelodysplastic syndromes. Blood. 2019;: pubmed 出版商
Liu M, Xiao C, Sun M, Tan M, Hu L, Yu Q. Xanthatin inhibits STAT3 and NF-κB signalling by covalently binding to JAK and IKK kinases. J Cell Mol Med. 2019;23:4301-4312 pubmed 出版商
Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, et al. Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Cancer Cell. 2019;35:677-691.e10 pubmed 出版商
Kim D, Park H, Park H, Lee J, Ko C, Gye M, et al. Estrogen receptor α in T cells suppresses follicular helper T cell responses and prevents autoimmunity. Exp Mol Med. 2019;51:41 pubmed 出版商
Pavel Dinu M, Wiebking V, Dejene B, Srifa W, Mantri S, Nicolas C, et al. Gene correction for SCID-X1 in long-term hematopoietic stem cells. Nat Commun. 2019;10:1634 pubmed 出版商
Zhang R, Qi F, Zhao F, Li G, Shao S, Zhang X, et al. Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer. Cell Death Dis. 2019;10:273 pubmed 出版商
Aho E, Wang J, Gogliotti R, Howard G, Phan J, Acharya P, et al. Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Rep. 2019;26:2916-2928.e13 pubmed 出版商
Martinez A, Miller W. Enabling Large-Scale Ex Vivo Production of Megakaryocytes from CD34+ Cells Using Gas-Permeable Surfaces. Stem Cells Transl Med. 2019;8:658-670 pubmed 出版商
Halvarsson C, Rörby E, Eliasson P, Lang S, Soneji S, Jönsson J. Putative role of NF-kB but not HIF-1α in hypoxia-dependent regulation of oxidative stress in hematopoietic stem and progenitor cells. Antioxid Redox Signal. 2019;: pubmed 出版商
Chen C, Bhasin S, Khanna P, Joshi M, Joslin P, Saxena R, et al. Study of Cathepsin B inhibition in VEGFR TKI treated human renal cell carcinoma xenografts. Oncogenesis. 2019;8:15 pubmed 出版商
Zou H, Chen Q, Zhang A, Wang S, Wu H, Yuan Y, et al. MPC1 deficiency accelerates lung adenocarcinoma progression through the STAT3 pathway. Cell Death Dis. 2019;10:148 pubmed 出版商
Herviou L, Jourdan M, Martinez A, Cavalli G, Moreaux J. EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation. Leukemia. 2019;: pubmed 出版商
Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed 出版商
Wieser V, Tsibulak I, Degasper C, Welponer H, Leitner K, Parson W, et al. Tumor necrosis factor receptor modulator spermatogenesis-associated protein 2 is a novel predictor of outcome in ovarian cancer. Cancer Sci. 2019;110:1117-1126 pubmed 出版商
Edsbäcker E, Serviss J, Kolosenko I, Palm Apergi C, De Milito A, Tamm K. STAT3 is activated in multicellular spheroids of colon carcinoma cells and mediates expression of IRF9 and interferon stimulated genes. Sci Rep. 2019;9:536 pubmed 出版商
Wimmer R, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, et al. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019;565:505-510 pubmed 出版商
Stephenson S, Care M, Fan I, Zougman A, Westhead D, Doody G, et al. Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells. J Immunol. 2019;202:1287-1300 pubmed 出版商
Harada K, Ihara F, Takami M, Kamata T, Mise N, Yoshizawa H, et al. Soluble factors derived from neuroblastoma cell lines suppress dendritic cell differentiation and activation. Cancer Sci. 2019;110:888-902 pubmed 出版商
Choi H, Chung T, Choi H, Han J, Choi J, Kim C, et al. Increased α2-6 sialylation of endometrial cells contributes to the development of endometriosis. Exp Mol Med. 2018;50:164 pubmed 出版商
Osorio F, Rosendahl Huber A, Oka R, Verheul M, Patel S, Hasaart K, et al. Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis. Cell Rep. 2018;25:2308-2316.e4 pubmed 出版商
Paupert J, Espinosa E, Cenac N, Robert V, Laharrague P, Evrard S, et al. Rapid and Efficient Production of Human Functional Mast Cells through a Three-Dimensional Culture of Adipose Tissue-Derived Stromal Vascular Cells. J Immunol. 2018;201:3815-3821 pubmed 出版商
Petrillo C, Thorne L, Unali G, Schiroli G, Giordano A, Piras F, et al. Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells. Cell Stem Cell. 2018;23:820-832.e9 pubmed 出版商
Yen J, Fiorino M, Liu Y, Paula S, Clarkson S, Quinn L, et al. TRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem Cells. Sci Rep. 2018;8:16304 pubmed 出版商
Lomova A, Clark D, Campo Fernandez B, Flores Bjurström C, Kaufman M, Fitz Gibbon S, et al. Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair. Stem Cells. 2019;37:284-294 pubmed 出版商
Wroblewska A, Dhainaut M, Ben Zvi B, Rose S, Park E, Amir E, et al. Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens. Cell. 2018;175:1141-1155.e16 pubmed 出版商
Otsuka Y, Watanabe E, Shinya E, Okura S, Saeki H, Geijtenbeek T, et al. Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells. J Immunol. 2018;201:3006-3016 pubmed 出版商
Latham S, Ehmke N, Reinke P, Taft M, Eicke D, Reindl T, et al. Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia. Nat Commun. 2018;9:4250 pubmed 出版商
Su S, Zhao J, Xing Y, Zhang X, Liu J, Ouyang Q, et al. Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages. Cell. 2018;175:442-457.e23 pubmed 出版商
Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch L, Eckert D, et al. A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. Nat Commun. 2018;9:4047 pubmed 出版商
Balcerek J, Jiang J, Li Y, Jiang Q, Holdreith N, Singh B, et al. Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia. Nat Commun. 2018;9:3915 pubmed 出版商
Al Maskari M, Care M, Robinson E, Cocco M, Tooze R, Doody G. Site-1 protease function is essential for the generation of antibody secreting cells and reprogramming for secretory activity. Sci Rep. 2018;8:14338 pubmed 出版商
Shastri A, Choudhary G, Teixeira M, Gordon Mitchell S, Ramachandra N, Bernard L, et al. Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells. J Clin Invest. 2018;128:5479-5488 pubmed 出版商
Tusa I, Cheloni G, Poteti M, Gozzini A, DeSouza N, Shan Y, et al. Targeting the Extracellular Signal-Regulated Kinase 5 Pathway to Suppress Human Chronic Myeloid Leukemia Stem Cells. Stem Cell Reports. 2018;11:929-943 pubmed 出版商
Zhang P, He F, Bai J, Yamamoto S, Chen S, Zhang L, et al. Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy. J Clin Invest. 2018;128:5383-5398 pubmed 出版商
Pan Y, Chen C, Chan Y, Wang H, Chien F, Chen Y, et al. STAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas. Nat Commun. 2018;9:3696 pubmed 出版商
Toofan P, Busch C, Morrison H, O Brien S, Jørgensen H, Copland M, et al. Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal. Cell Death Dis. 2018;9:927 pubmed 出版商
Kauts M, De Leo B, Rodríguez Seoane C, Ronn R, Glykofrydis F, Maglitto A, et al. Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells. Stem Cell Reports. 2018;11:1009-1020 pubmed 出版商
Shiozawa Y, Malcovati L, Galli A, Sato Otsubo A, Kataoka K, Sato Y, et al. Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia. Nat Commun. 2018;9:3649 pubmed 出版商
Pearson M, Bik M, Ospelt C, Naylor A, Wehmeyer C, Jones S, et al. Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts. Sci Rep. 2018;8:12887 pubmed 出版商
Minzel W, Venkatachalam A, Fink A, Hung E, Brachya G, Burstain I, et al. Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell. 2018;175:171-185.e25 pubmed 出版商
Zhang H, Xu Z, Lin H, Li M, Xia T, Cui K, et al. TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis. Nat Commun. 2018;9:3441 pubmed 出版商
Tegowski M, Fan C, Baldwin A. Thioridazine inhibits self-renewal in breast cancer cells via DRD2-dependent STAT3 inhibition, but induces a G1 arrest independent of DRD2. J Biol Chem. 2018;293:15977-15990 pubmed 出版商
Jalali S, Price Troska T, Paludo J, Villasboas J, Kim H, Yang Z, et al. Soluble PD-1 ligands regulate T-cell function in Waldenstrom macroglobulinemia. Blood Adv. 2018;2:1985-1997 pubmed 出版商
Muliaditan T, Caron J, Okesola M, Opzoomer J, Kosti P, Georgouli M, et al. Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis. Nat Commun. 2018;9:2951 pubmed 出版商
Pulikkan J, Hegde M, Ahmad H, Belaghzal H, Illendula A, Yu J, et al. CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia. Cell. 2018;174:172-186.e21 pubmed 出版商
Di Domenico E, Cavallo I, Bordignon V, Prignano G, Sperduti I, Gurtner A, et al. Inflammatory cytokines and biofilm production sustain Staphylococcus aureus outgrowth and persistence: a pivotal interplay in the pathogenesis of Atopic Dermatitis. Sci Rep. 2018;8:9573 pubmed 出版商
Jiao J, Zhang R, Li Z, Yin Y, Fang X, Ding X, et al. Nuclear Smad6 promotes gliomagenesis by negatively regulating PIAS3-mediated STAT3 inhibition. Nat Commun. 2018;9:2504 pubmed 出版商
Khanna P, Lee J, Sereemaspun A, Lee H, Baeg G. GRAMD1B regulates cell migration in breast cancer cells through JAK/STAT and Akt signaling. Sci Rep. 2018;8:9511 pubmed 出版商
Chen Z, Huang L, Li M, Meng L, Ying S, Xu A. Inhibitory effects of isocryptotanshinone on gastric cancer. Sci Rep. 2018;8:9307 pubmed 出版商
Corrigan D, Luchsinger L, Justino de Almeida M, Williams L, Strikoudis A, Snoeck H. PRDM16 isoforms differentially regulate normal and leukemic hematopoiesis and inflammatory gene signature. J Clin Invest. 2018;128:3250-3264 pubmed 出版商
Sumide K, Matsuoka Y, Kawamura H, Nakatsuka R, Fujioka T, Asano H, et al. A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells. Nat Commun. 2018;9:2202 pubmed 出版商
Kim M, Yu K, Kenderian S, Ruella M, Chen S, Shin T, et al. Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia. Cell. 2018;173:1439-1453.e19 pubmed 出版商
Razidlo G, Burton K, McNiven M. Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42. J Biol Chem. 2018;293:11143-11153 pubmed 出版商
Derosa B, El Hokayem J, Artimovich E, Garcia Serje C, Phillips A, van Booven D, et al. Convergent Pathways in Idiopathic Autism Revealed by Time Course Transcriptomic Analysis of Patient-Derived Neurons. Sci Rep. 2018;8:8423 pubmed 出版商
Maclean G, McEldoon J, Huang J, Allred J, Canver M, Orkin S. Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells. Sci Rep. 2018;8:8001 pubmed 出版商
Wang W, Li F, Xu Y, Wei J, Zhang Y, Yang H, et al. JAK1-mediated Sirt1 phosphorylation functions as a negative feedback of the JAK1-STAT3 pathway. J Biol Chem. 2018;293:11067-11075 pubmed 出版商
Wu R, Zeng J, Yuan J, Deng X, Huang Y, Chen L, et al. MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation. J Clin Invest. 2018;128:2551-2568 pubmed 出版商
Li Z, Li S, Li R, Zhu H, Liu X, Guo X, et al. Leukaemic alterations of IKZF1 prime stemness and malignancy programs in human lymphocytes. Cell Death Dis. 2018;9:526 pubmed 出版商
Uenishi G, Jung H, Kumar A, Park M, Hadland B, McLeod E, et al. NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells. Nat Commun. 2018;9:1828 pubmed 出版商
Nemoto M, Hattori H, Maeda N, Akita N, Muramatsu H, Moritani S, et al. Compound heterozygous TYK2 mutations underlie primary immunodeficiency with T-cell lymphopenia. Sci Rep. 2018;8:6956 pubmed 出版商
Hyrenius Wittsten A, Pilheden M, Sturesson H, Hansson J, Walsh M, Song G, et al. De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia. Nat Commun. 2018;9:1770 pubmed 出版商
Wang Y, Fu D, Chen Y, Su J, Wang Y, Li X, et al. G3BP1 promotes tumor progression and metastasis through IL-6/G3BP1/STAT3 signaling axis in renal cell carcinomas. Cell Death Dis. 2018;9:501 pubmed 出版商
Biechonski S, Olender L, Zipin Roitman A, Yassin M, Aqaqe N, Marcu Malina V, et al. Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation. Sci Rep. 2018;8:6071 pubmed 出版商
Brown M, Johnson L, Leone D, Májek P, Vaahtomeri K, Senfter D, et al. Lymphatic exosomes promote dendritic cell migration along guidance cues. J Cell Biol. 2018;217:2205-2221 pubmed 出版商
Chen C, Li X, Ge G, Liu J, Biju K, Laing S, et al. GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark mice. Sci Rep. 2018;8:5460 pubmed 出版商
L italien L, Orozco O, Abrams T, Cantagallo L, Connor A, Desai J, et al. Mechanistic Insights of an Immunological Adverse Event Induced by an Anti-KIT Antibody Drug Conjugate and Mitigation Strategies. Clin Cancer Res. 2018;24:3465-3474 pubmed 出版商
Zhang Y, Xia F, Liu X, Yu Z, Xie L, Liu L, et al. JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/?-catenin/CCND1 signaling. J Clin Invest. 2018;128:1737-1751 pubmed 出版商
Tanaka R, Masuda H, Fujimura S, Ito Hirano R, Arita K, Kakinuma Y, et al. Quality-Quantity Control Culture Enhances Vasculogenesis and Wound Healing Efficacy of Human Diabetic Peripheral Blood CD34+ Cells. Stem Cells Transl Med. 2018;7:428-438 pubmed 出版商
Voglis S, Moos S, Kloos L, Wanke F, Zayoud M, Pelczar P, et al. Regulation of IL-22BP in psoriasis. Sci Rep. 2018;8:5085 pubmed 出版商
Jones D, Jenney A, Joughin B, Sorger P, Lauffenburger D. Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition. Sci Signal. 2018;11: pubmed 出版商
Lummertz da Rocha E, Rowe R, Lundin V, Malleshaiah M, Jha D, Rambo C, et al. Reconstruction of complex single-cell trajectories using CellRouter. Nat Commun. 2018;9:892 pubmed 出版商
Yamauchi T, Masuda T, Canver M, Seiler M, Semba Y, Shboul M, et al. Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS. Cancer Cell. 2018;33:386-400.e5 pubmed 出版商
Danziger O, Pupko T, Bacharach E, Ehrlich M. Interleukin-6 and Interferon-α Signaling via JAK1-STAT Differentially Regulate Oncolytic versus Cytoprotective Antiviral States. Front Immunol. 2018;9:94 pubmed 出版商
Shee K, Yang W, Hinds J, Hampsch R, Varn F, Traphagen N, et al. Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. J Exp Med. 2018;215:895-910 pubmed 出版商
Hecht I, Toporik A, Podojil J, Vaknin I, Cojocaru G, Oren A, et al. ILDR2 Is a Novel B7-like Protein That Negatively Regulates T Cell Responses. J Immunol. 2018;200:2025-2037 pubmed 出版商
Zhao M, Tan Y, Peng Q, Huang C, Guo Y, Liang G, et al. IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic regulation. Nat Commun. 2018;9:583 pubmed 出版商
Ritter A, Friemel A, Kreis N, Hoock S, Roth S, Kielland Kaisen U, et al. Primary Cilia Are Dysfunctional in Obese Adipose-Derived Mesenchymal Stem Cells. Stem Cell Reports. 2018;10:583-599 pubmed 出版商
Zhang X, Lu H, Hong W, Liu L, Wang S, Zhou M, et al. Tyrphostin B42 attenuates trichostatin A-mediated resistance in pancreatic cancer cells by antagonizing IL-6/JAK2/STAT3 signaling. Oncol Rep. 2018;39:1892-1900 pubmed 出版商
Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed 出版商
Wang H, Liu C, Liu X, Wang M, Wu D, Gao J, et al. MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1. Stem Cell Reports. 2018;10:447-460 pubmed 出版商
Vo L, Kinney M, Liu X, Zhang Y, Barragan J, Sousa P, et al. Regulation of embryonic haematopoietic multipotency by EZH1. Nature. 2018;553:506-510 pubmed 出版商
Duarte D, Hawkins E, Akinduro O, Ang H, De Filippo K, Kong I, et al. Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML. Cell Stem Cell. 2018;22:64-77.e6 pubmed 出版商
Kunimoto H, Meydan C, Nazir A, Whitfield J, Shank K, Rapaport F, et al. Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity. Cancer Cell. 2018;33:44-59.e8 pubmed 出版商
Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed 出版商
Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y, et al. R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. Cell. 2018;172:90-105.e23 pubmed 出版商
Chen J, Adamiak W, Huang G, Atasoy U, Rostami A, Yu S. Interaction of RNA-binding protein HuR and miR-466i regulates GM-CSF expression. Sci Rep. 2017;7:17233 pubmed 出版商
Zhao B, Mei Y, Cao L, Zhang J, Sumagin R, Yang J, et al. Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms. J Clin Invest. 2018;128:125-140 pubmed 出版商
Mori R, Wauman J, Icardi L, Van der Heyden J, De Cauwer L, Peelman F, et al. TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity. Sci Rep. 2017;7:15919 pubmed 出版商
Angelos M, Abrahante J, Blum R, Kaufman D. Single Cell Resolution of Human Hematoendothelial Cells Defines Transcriptional Signatures of Hemogenic Endothelium. Stem Cells. 2018;36:206-217 pubmed 出版商
Wang S, Liang K, Hu Q, Li P, Song J, Yang Y, et al. JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. J Clin Invest. 2017;127:4498-4515 pubmed 出版商
Zhao H, Wang X, Yi P, Si Y, Tan P, He J, et al. KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression. Nat Commun. 2017;8:1428 pubmed 出版商
Nastasi C, Fredholm S, Willerslev Olsen A, Hansen M, Bonefeld C, Geisler C, et al. Butyrate and propionate inhibit antigen-specific CD8+ T cell activation by suppressing IL-12 production by antigen-presenting cells. Sci Rep. 2017;7:14516 pubmed 出版商
Li Y, Jin C, Bai H, Gao Y, Sun S, Chen L, et al. Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation. Blood. 2017;: pubmed 出版商
Mayer U, Benditz A, Grassel S. miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment. Sci Rep. 2017;7:13297 pubmed 出版商
McCurdy S, Baumer Y, Toulmin E, Lee B, Boisvert W. Macrophage-Specific Expression of IL-37 in Hyperlipidemic Mice Attenuates Atherosclerosis. J Immunol. 2017;199:3604-3613 pubmed 出版商
Malik S, Sadhu S, Elesela S, Pandey R, Chawla A, Sharma D, et al. Transcription factor Foxo1 is essential for IL-9 induction in T helper cells. Nat Commun. 2017;8:815 pubmed 出版商
Eitas T, Stepp W, Sjeklocha L, Long C, Riley C, Callahan J, et al. Differential regulation of innate immune cytokine production through pharmacological activation of Nuclear Factor-Erythroid-2-Related Factor 2 (NRF2) in burn patient immune cells and monocytes. PLoS ONE. 2017;12:e0184164 pubmed 出版商
Lei C, Su H, Ye C, Tang H, GAO P, Wan C, et al. The classic signalling and trans-signalling of interleukin-6 are both injurious in podocyte under high glucose exposure. J Cell Mol Med. 2018;22:251-260 pubmed 出版商
Zitti B, Molfetta R, Fionda C, Quatrini L, Stabile H, Lecce M, et al. Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells. Sci Rep. 2017;7:10445 pubmed 出版商
Xu L, Chen X, Shen M, Yang D, Fang L, Weng G, et al. Inhibition of IL-6-JAK/Stat3 signaling in castration-resistant prostate cancer cells enhances the NK cell-mediated cytotoxicity via alteration of PD-L1/NKG2D ligand levels. Mol Oncol. 2018;12:269-286 pubmed 出版商
Mine S, Hishima T, Suganuma A, Fukumoto H, Sato Y, Kataoka M, et al. Interleukin-6-dependent growth in a newly established plasmablastic lymphoma cell line and its therapeutic targets. Sci Rep. 2017;7:10188 pubmed 出版商
Zeng Z, Li M, Wang M, Wu X, Li Q, Ning Q, et al. Increased expression of Siglec-9 in chronic obstructive pulmonary disease. Sci Rep. 2017;7:10116 pubmed 出版商
Chen Q, Yang D, Zong H, Zhu L, Wang L, Wang X, et al. Growth-induced stress enhances epithelial-mesenchymal transition induced by IL-6 in clear cell renal cell carcinoma via the Akt/GSK-3?/?-catenin signaling pathway. Oncogenesis. 2017;6:e375 pubmed 出版商
Wiśnik E, Płoszaj T, Robaszkiewicz A. Downregulation of PARP1 transcription by promoter-associated E2F4-RBL2-HDAC1-BRM complex contributes to repression of pluripotency stem cell factors in human monocytes. Sci Rep. 2017;7:9483 pubmed 出版商
Cutler S, Doecke J, Ghazawi I, Yang J, Griffiths L, Spring K, et al. Novel STAT binding elements mediate IL-6 regulation of MMP-1 and MMP-3. Sci Rep. 2017;7:8526 pubmed 出版商
Yi L, Shen H, Zhao M, Shao P, Liu C, Cui J, et al. Inflammation-mediated SOD-2 upregulation contributes to epithelial-mesenchymal transition and migration of tumor cells in aflatoxin G1-induced lung adenocarcinoma. Sci Rep. 2017;7:7953 pubmed 出版商
Dahlin J, Ekoff M, Grootens J, Löf L, Amini R, Hagberg H, et al. KIT signaling is dispensable for human mast cell progenitor development. Blood. 2017;130:1785-1794 pubmed 出版商
Schwerd T, Twigg S, Aschenbrenner D, Manrique S, Miller K, Taylor I, et al. A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis. J Exp Med. 2017;214:2547-2562 pubmed 出版商
Tripathi P, Rodríguez Muela N, Klim J, de Boer A, Agrawal S, Sandoe J, et al. Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1. Stem Cell Reports. 2017;9:667-680 pubmed 出版商
Zhang Y, Ma C, Lawrence M, Break T, O Connell M, Lyons J, et al. PD-L1 up-regulation restrains Th17 cell differentiation in STAT3 loss- and STAT1 gain-of-function patients. J Exp Med. 2017;214:2523-2533 pubmed 出版商
Mingay M, Chaturvedi A, Bilenky M, Cao Q, Jackson L, Hui T, et al. Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia. Leukemia. 2018;32:11-20 pubmed 出版商
di Tullio A, Passaro D, Rouault Pierre K, Purewal S, Bonnet D. Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation. Stem Cell Reports. 2017;9:5-11 pubmed 出版商
Karjalainen R, Pemovska T, Popa M, Liu M, Javarappa K, Majumder M, et al. JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML. Blood. 2017;130:789-802 pubmed 出版商
Montoya M, Maul J, Singh P, Pua H, Dahlström F, Wu N, et al. A Distinct Inhibitory Function for miR-18a in Th17 Cell Differentiation. J Immunol. 2017;199:559-569 pubmed 出版商
Peng K, Liu Y, Li Y, Yen B, Yen M. Extracellular matrix protein laminin enhances mesenchymal stem cell (MSC) paracrine function through ?v?3/CD61 integrin to reduce cardiomyocyte apoptosis. J Cell Mol Med. 2017;21:1572-1583 pubmed 出版商
Yang P, Xiao Y, Luo X, Zhao Y, Zhao L, Wang Y, et al. Inflammatory stress promotes the development of obesity-related chronic kidney disease via CD36 in mice. J Lipid Res. 2017;58:1417-1427 pubmed 出版商
Angelos M, Ruh P, Webber B, Blum R, Ryan C, Bendzick L, et al. Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells. Blood. 2017;129:3428-3439 pubmed 出版商
Arumugakani G, Stephenson S, Newton D, Rawstron A, Emery P, Doody G, et al. Early Emergence of CD19-Negative Human Antibody-Secreting Cells at the Plasmablast to Plasma Cell Transition. J Immunol. 2017;198:4618-4628 pubmed 出版商
Pattarini L, Trichot C, Bogiatzi S, Grandclaudon M, Meller S, Keuylian Z, et al. TSLP-activated dendritic cells induce human T follicular helper cell differentiation through OX40-ligand. J Exp Med. 2017;214:1529-1546 pubmed 出版商
Mohr S, Doebele C, Comoglio F, Berg T, Beck J, Bohnenberger H, et al. Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. Cancer Cell. 2017;31:549-562.e11 pubmed 出版商
Cantor J, Abu Remaileh M, Kanarek N, Freinkman E, Gao X, Louissaint A, et al. Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase. Cell. 2017;169:258-272.e17 pubmed 出版商
Dhenge A, Limbkar K, Melinkeri S, Kale V, Limaye L. Arachidonic acid and Docosahexanoic acid enhance platelet formation from human apheresis-derived CD34+ cells. Cell Cycle. 2017;16:979-990 pubmed 出版商
O Brien K, Farrar J, Vlachos A, Anderson S, Tsujiura C, Lichtenberg J, et al. Molecular convergence in ex vivo models of Diamond-Blackfan anemia. Blood. 2017;129:3111-3120 pubmed 出版商
Ueshima C, Kataoka T, Takei Y, Hirata M, Sugimoto A, Hirokawa M, et al. CEACAM1 long isoform has opposite effects on the growth of human mastocytosis and medullary thyroid carcinoma cells. Cancer Med. 2017;6:845-856 pubmed 出版商
Guan X, Qin M, Zhang Y, Wang Y, Shen B, Ren Z, et al. Safety and Efficacy of Megakaryocytes Induced from Hematopoietic Stem Cells in Murine and Nonhuman Primate Models. Stem Cells Transl Med. 2017;6:897-909 pubmed 出版商
Wu J, Yin L, Shi C, Li Q, Duan P, Huang J, et al. MAOA-Dependent Activation of Shh-IL6-RANKL Signaling Network Promotes Prostate Cancer Metastasis by Engaging Tumor-Stromal Cell Interactions. Cancer Cell. 2017;31:368-382 pubmed 出版商
Junk D, Bryson B, Smigiel J, Parameswaran N, Bartel C, Jackson M. Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling. Oncogene. 2017;36:4001-4013 pubmed 出版商
Ho C, Chhabra A, Starkl P, Schnorr P, Wilmes S, Moraga I, et al. Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling. Cell. 2017;168:1041-1052.e18 pubmed 出版商
Chen X, Clark J, Wunderlich M, Fan C, Davis A, Chen S, et al. Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine. Autophagy. 2017;13:955-966 pubmed 出版商
He H, Kuriyan A, Su C, Mahabole M, Zhang Y, Zhu Y, et al. Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3. Sci Rep. 2017;7:43736 pubmed 出版商
Ishizawa J, Sugihara E, Kuninaka S, Mogushi K, Kojima K, Benton C, et al. FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia. Blood. 2017;129:1958-1968 pubmed 出版商
Lyons J, Liu Y, Ma C, Yu X, O Connell M, Lawrence M, et al. ERBIN deficiency links STAT3 and TGF-? pathway defects with atopy in humans. J Exp Med. 2017;214:669-680 pubmed 出版商
Endo S, Nakata K, Ohuchida K, Takesue S, Nakayama H, Abe T, et al. Autophagy Is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice. Gastroenterology. 2017;152:1492-1506.e24 pubmed 出版商
Akoto C, Davies D, Swindle E. Mast cells are permissive for rhinovirus replication: potential implications for asthma exacerbations. Clin Exp Allergy. 2017;47:351-360 pubmed 出版商
Darvin P, Joung Y, Kang D, Sp N, Byun H, Hwang T, et al. Tannic acid inhibits EGFR/STAT1/3 and enhances p38/STAT1 signalling axis in breast cancer cells. J Cell Mol Med. 2017;21:720-734 pubmed 出版商
Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Nakata T, Murano T, et al. PGE2 is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells. Sci Rep. 2016;6:36795 pubmed 出版商
Azad P, Zhao H, Cabrales P, Ronen R, Zhou D, Poulsen O, et al. Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease. J Exp Med. 2016;213:2729-2744 pubmed
Suurmond J, Habets K, Dorjée A, Huizinga T, Toes R. Expansion of Th17 Cells by Human Mast Cells Is Driven by Inflammasome-Independent IL-1?. J Immunol. 2016;197:4473-4481 pubmed
Gu H, Chen C, Hao X, Wang C, Zhang X, Li Z, et al. Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis. J Clin Invest. 2016;126:4537-4553 pubmed 出版商
Gregory M, D Alessandro A, Alvarez Calderon F, Kim J, Nemkov T, Adane B, et al. ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia. Proc Natl Acad Sci U S A. 2016;113:E6669-E6678 pubmed
Serr I, Fürst R, Ott V, Scherm M, Nikolaev A, Gökmen F, et al. miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity. Proc Natl Acad Sci U S A. 2016;113:E6659-E6668 pubmed
Adair J, Waters T, Haworth K, Kubek S, Trobridge G, Hocum J, et al. Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy. Nat Commun. 2016;7:13173 pubmed 出版商
Stevens M, Maire C, Chou N, Murakami M, Knoff D, Kikuchi Y, et al. Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate. Nat Biotechnol. 2016;34:1161-1167 pubmed 出版商
Cheung K, Jarrett R, Subramaniam S, Salimi M, Gutowska Owsiak D, Chen Y, et al. Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a. J Exp Med. 2016;213:2399-2412 pubmed
Wang Y, Ma C, Ling Y, Bousfiha A, Camcioglu Y, Jacquot S, et al. Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. J Exp Med. 2016;213:2413-2435 pubmed
Jin Y, Zhou J, Xu F, Jin B, Cui L, Wang Y, et al. Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia. J Clin Invest. 2016;126:3961-3980 pubmed 出版商
Sykes D, Kfoury Y, Mercier F, Wawer M, Law J, Haynes M, et al. Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. Cell. 2016;167:171-186.e15 pubmed 出版商
Szatmári Tóth M, Kristóf E, Veréb Z, Akhtar S, Facskó A, Fésüs L, et al. Clearance of autophagy-associated dying retinal pigment epithelial cells - a possible source for inflammation in age-related macular degeneration. Cell Death Dis. 2016;7:e2367 pubmed 出版商
Ou Z, Niu X, He W, Chen Y, Song B, Xian Y, et al. The Combination of CRISPR/Cas9 and iPSC Technologies in the Gene Therapy of Human ?-thalassemia in Mice. Sci Rep. 2016;6:32463 pubmed 出版商
Chen J, Lai Y, Tsai H, Kuo C, Yen B, Yeh S, et al. The oncometabolite R-2-hydroxyglutarate activates NF-?B-dependent tumor-promoting stromal niche for acute myeloid leukemia cells. Sci Rep. 2016;6:32428 pubmed 出版商
Aggelakopoulou M, Kourepini E, Paschalidis N, Simoes D, Kalavrizioti D, Dimisianos N, et al. ER?-Dependent Direct Suppression of Human and Murine Th17 Cells and Treatment of Established Central Nervous System Autoimmunity by a Neurosteroid. J Immunol. 2016;197:2598-609 pubmed 出版商
Comte D, Karampetsou M, Kis Toth K, Yoshida N, Bradley S, Mizui M, et al. Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2016;113:9321-6 pubmed 出版商
Sanges D, Simonte G, Di Vicino U, Romo N, Pinilla I, Nicolas M, et al. Reprogramming Müller glia via in vivo cell fusion regenerates murine photoreceptors. J Clin Invest. 2016;126:3104-16 pubmed 出版商
Ma C, Wong N, Rao G, Nguyen A, Avery D, Payne K, et al. Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets. J Exp Med. 2016;213:1589-608 pubmed 出版商
Care M, Stephenson S, Barnes N, Fan I, Zougman A, El Sherbiny Y, et al. Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity. J Immunol. 2016;197:1447-59 pubmed 出版商
Pikman Y, Puissant A, Alexe G, Furman A, Chen L, Frumm S, et al. Targeting MTHFD2 in acute myeloid leukemia. J Exp Med. 2016;213:1285-306 pubmed 出版商
Tuccitto A, Tazzari M, Beretta V, Rini F, Miranda C, Greco A, et al. Immunomodulatory Factors Control the Fate of Melanoma Tumor Initiating Cells. Stem Cells. 2016;34:2449-2460 pubmed 出版商
Guo B, Zhang L, Chiorazzi N, Rothstein T. IL-4 rescues surface IgM expression in chronic lymphocytic leukemia. Blood. 2016;128:553-62 pubmed 出版商
Chen J, Gao X, Yang L, Fu W, Liang L, Li J, et al. Disruption of Notch signaling aggravates irradiation-induced bone marrow injury, which is ameliorated by a soluble Dll1 ligand through Csf2rb2 upregulation. Sci Rep. 2016;6:26003 pubmed 出版商
Nagashima H, Okuyama Y, Hayashi T, Ishii N, So T. TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development. J Immunol. 2016;196:4082-9 pubmed 出版商
Kishton R, Barnes C, Nichols A, Cohen S, Gerriets V, Siska P, et al. AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival. Cell Metab. 2016;23:649-62 pubmed 出版商
Korfi K, Smith M, Swan J, Somervaille T, Dhomen N, Marais R. BIM mediates synergistic killing of B-cell acute lymphoblastic leukemia cells by BCL-2 and MEK inhibitors. Cell Death Dis. 2016;7:e2177 pubmed 出版商
Drujont L, Lemoine A, Moreau A, Bienvenu G, Lancien M, Cens T, et al. RORγt+ cells selectively express redundant cation channels linked to the Golgi apparatus. Sci Rep. 2016;6:23682 pubmed 出版商
Grover A, Sanjuan Pla A, Thongjuea S, Carrelha J, Giustacchini A, Gambardella A, et al. Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells. Nat Commun. 2016;7:11075 pubmed 出版商
Bararia D, Kwok H, Welner R, Numata A, Sárosi M, Yang H, et al. Acetylation of C/EBPα inhibits its granulopoietic function. Nat Commun. 2016;7:10968 pubmed 出版商
Moreno Lorenzana D, Avilés Vazquez S, Sandoval Esquivel M, Alvarado Moreno A, Ortiz Navarrete V, Torres Martínez H, et al. CDKIs p18(INK4c) and p57(Kip2) are involved in quiescence of CML leukemic stem cells after treatment with TKI. Cell Cycle. 2016;15:1276-87 pubmed 出版商
Liu F, Zhang W, Yang F, Feng T, Zhou M, Yu Y, et al. Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling. Sci Rep. 2016;6:21260 pubmed 出版商
Zhu N, Chen M, Eng R, DeJong J, Sinha A, Rahnamay N, et al. MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C. J Clin Invest. 2016;126:997-1011 pubmed 出版商
Sweeney C, Teng R, Wang H, Merling R, Lee J, Choi U, et al. Molecular Analysis of Neutrophil Differentiation from Human Induced Pluripotent Stem Cells Delineates the Kinetics of Key Regulators of Hematopoiesis. Stem Cells. 2016;34:1513-26 pubmed 出版商
Jin K, Su K, Li T, Zhu X, Wang Q, Ge R, et al. Hepatic Premalignant Alterations Triggered by Human Nephrotoxin Aristolochic Acid I in Canines. Cancer Prev Res (Phila). 2016;9:324-34 pubmed 出版商
Llibre A, López Macías C, Marafioti T, Mehta H, Partridge A, Kanzig C, et al. LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation. J Immunol. 2016;196:2085-94 pubmed 出版商
D Souza S, Maufort J, Kumar A, Zhang J, Smuga Otto K, Thomson J, et al. GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells. Stem Cell Reports. 2016;6:243-56 pubmed 出版商
Abbonante V, Di Buduo C, Gruppi C, Malara A, Gianelli U, Celesti G, et al. Thrombopoietin/TGF-β1 Loop Regulates Megakaryocyte Extracellular Matrix Component Synthesis. Stem Cells. 2016;34:1123-33 pubmed 出版商
Xie X, Yang P, Zhang Y, Zhang P, Wang L, Ding Y, et al. Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci Rep. 2015;5:18115 pubmed 出版商
Dahlin J, Malinovschi A, Öhrvik H, Sandelin M, Janson C, Alving K, et al. Lin- CD34hi CD117int/hi FcεRI+ cells in human blood constitute a rare population of mast cell progenitors. Blood. 2016;127:383-91 pubmed 出版商
Thompson M, Larson M, Vidrine A, Barrios K, Navarro F, Meyers K, et al. FOXO3-NF-κB RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function. J Immunol. 2015;195:5637-47 pubmed 出版商
Doty R, Phelps S, Shadle C, Sanchez Bonilla M, Keel S, Abkowitz J. Coordinate expression of heme and globin is essential for effective erythropoiesis. J Clin Invest. 2015;125:4681-91 pubmed 出版商
Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, et al. MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment. Nat Commun. 2015;6:8755 pubmed 出版商
Wee Z, Yatim S, Kohlbauer V, Feng M, Goh J, Bao Y, et al. IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel. Nat Commun. 2015;6:8746 pubmed 出版商
Kumar K, Pillong M, Kunze J, Burghardt I, Weller M, Grotzer M, et al. Computer-assisted quantification of motile and invasive capabilities of cancer cells. Sci Rep. 2015;5:15338 pubmed 出版商
Yang P, Zhao Y, Zhao L, Yuan J, Chen Y, Varghese Z, et al. Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo. Sci Rep. 2015;5:14959 pubmed 出版商
Lu J, Zeng H, Liang Z, Chen L, Zhang L, Zhang H, et al. Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets. Sci Rep. 2015;5:14739 pubmed 出版商
Mailer R, Joly A, Liu S, Elias S, Tegner J, Andersson J. IL-1β promotes Th17 differentiation by inducing alternative splicing of FOXP3. Sci Rep. 2015;5:14674 pubmed 出版商
Cook K, Shpargel K, Starmer J, Whitfield Larry F, Conley B, Allard D, et al. T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX. Immunity. 2015;43:703-14 pubmed 出版商
Mittelberger F, Meyer C, Waetzig G, Zacharias M, Valentini E, Svergun D, et al. RAID3--An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity. RNA Biol. 2015;12:1043-53 pubmed 出版商
Cohen E, Scott I, Majithiya J, Rapley L, Kemp B, England E, et al. Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation. Nat Commun. 2015;6:8327 pubmed 出版商
Hsu P, Santner Nanan B, Hu M, Skarratt K, Lee C, Stormon M, et al. IL-10 Potentiates Differentiation of Human Induced Regulatory T Cells via STAT3 and Foxo1. J Immunol. 2015;195:3665-74 pubmed 出版商
Liu J, Zhou F, Chen Q, Kang A, Lu M, Liu W, et al. Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice. Sci Rep. 2015;5:13558 pubmed 出版商
Buechele C, Breese E, Schneidawind D, Lin C, Jeong J, Duque Afonso J, et al. MLL leukemia induction by genome editing of human CD34+ hematopoietic cells. Blood. 2015;126:1683-94 pubmed 出版商
Pundir P, MacDonald C, Kulka M. The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production. J Immunol. 2015;195:2774-87 pubmed 出版商
Sahoo A, Alekseev A, Tanaka K, Obertas L, Lerman B, Haymaker C, et al. Batf is important for IL-4 expression in T follicular helper cells. Nat Commun. 2015;6:7997 pubmed 出版商
Hammitzsch A, Tallant C, Fedorov O, O Mahony A, Brennan P, Hay D, et al. CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses. Proc Natl Acad Sci U S A. 2015;112:10768-73 pubmed 出版商
Liu R, Li X, Zhang Z, Zhou M, Sun Y, Su D, et al. Allogeneic mesenchymal stem cells inhibited T follicular helper cell generation in rheumatoid arthritis. Sci Rep. 2015;5:12777 pubmed 出版商
Martin Del Campo S, Levine K, Mundy Bosse B, Grignol V, Fairchild E, Campbell A, et al. The Raf Kinase Inhibitor Sorafenib Inhibits JAK-STAT Signal Transduction in Human Immune Cells. J Immunol. 2015;195:1995-2005 pubmed 出版商
Michailidou M, Melas I, Messinis D, Klamt S, Alexopoulos L, Kolisis F, et al. Network-Based Analysis of Nutraceuticals in Human Hepatocellular Carcinomas Reveals Mechanisms of Chemopreventive Action. CPT Pharmacometrics Syst Pharmacol. 2015;4:350-61 pubmed 出版商
Posch B, Irsara C, Gamper F, Herrmann M, Bindreither D, Fuchs D, et al. Allergenic Can f 1 and its human homologue Lcn-1 direct dendritic cells to induce divergent immune responses. J Cell Mol Med. 2015;19:2375-84 pubmed 出版商
Nayak R, Trump L, Aronow B, Myers K, Mehta P, Kalfa T, et al. Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells. J Clin Invest. 2015;125:3103-16 pubmed 出版商
Lopes J, Stylianou M, Nilsson G, Urban C. Opportunistic pathogen Candida albicans elicits a temporal response in primary human mast cells. Sci Rep. 2015;5:12287 pubmed 出版商
Chadet S, Ivanes F, Benoist L, Salmon Gandonnière C, Guibon R, Velge Roussel F, et al. Hypoxia/Reoxygenation Inhibits P2Y11 Receptor Expression and Its Immunosuppressive Activity in Human Dendritic Cells. J Immunol. 2015;195:651-60 pubmed 出版商
Hong S, Choi J, Lee S, Park Y, Park K, Lee J, et al. A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor β Subunit, Glycoprotein 130. J Immunol. 2015;195:237-45 pubmed 出版商
Guan Y, Zhang L, Li X, Zhang X, Liu S, Gao N, et al. Repression of Mammalian Target of Rapamycin Complex 1 Inhibits Intestinal Regeneration in Acute Inflammatory Bowel Disease Models. J Immunol. 2015;195:339-46 pubmed 出版商
Thakur R, Trivedi R, Rastogi N, Singh M, Mishra D. Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer. Sci Rep. 2015;5:10194 pubmed 出版商
Wilson R, Ives M, Rao G, Lau A, Payne K, Kobayashi M, et al. STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function. J Exp Med. 2015;212:855-64 pubmed 出版商
Li P, Shan J, Chen X, Zhang D, Su L, Huang X, et al. Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment. Cell Res. 2015;25:588-603 pubmed 出版商
Rouzbeh S, Kobari L, Cambot M, Mazurier C, Hebert N, Faussat A, et al. Molecular signature of erythroblast enucleation in human embryonic stem cells. Stem Cells. 2015;33:2431-41 pubmed 出版商
Meldi K, Qin T, Buchi F, Droin N, Sotzen J, Micol J, et al. Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia. J Clin Invest. 2015;125:1857-72 pubmed 出版商
Borkin D, He S, Miao H, Kempińska K, Pollock J, Chase J, et al. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 2015;27:589-602 pubmed 出版商
Zhang J, Jia J, Zhao L, Li X, Xie Q, Chen X, et al. Down-regulation of microRNA-9 leads to activation of IL-6/Jak/STAT3 pathway through directly targeting IL-6 in HeLa cell. Mol Carcinog. 2016;55:732-42 pubmed 出版商
Dasgupta M, Dermawan J, Willard B, Stark G. STAT3-driven transcription depends upon the dimethylation of K49 by EZH2. Proc Natl Acad Sci U S A. 2015;112:3985-90 pubmed 出版商
Lourenço S, Teixeira V, Kalber T, José R, Floto R, Janes S. Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors. J Immunol. 2015;194:3463-74 pubmed 出版商
Jean Gilles L, Braitch M, Latif M, Aram J, Fahey A, Edwards L, et al. Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells. Acta Physiol (Oxf). 2015;214:63-74 pubmed 出版商
Chavele K, Merry E, Ehrenstein M. Cutting edge: circulating plasmablasts induce the differentiation of human T follicular helper cells via IL-6 production. J Immunol. 2015;194:2482-5 pubmed 出版商
Wang Y, Xing F, Ye S, Xiao J, Di J, Zeng S, et al. Jagged-1 signaling suppresses the IL-6 and TGF-β treatment-induced Th17 cell differentiation via the reduction of RORγt/IL-17A/IL-17F/IL-23a/IL-12rb1. Sci Rep. 2015;5:8234 pubmed 出版商
Dai R, Rossello R, Chen C, Kessler J, Davison I, Hochgeschwender U, et al. Maintenance and neuronal differentiation of chicken induced pluripotent stem-like cells. Stem Cells Int. 2014;2014:182737 pubmed 出版商
Philip M, Funkhouser S, Chiu E, Phelps S, Delrow J, Cox J, et al. Heme exporter FLVCR is required for T cell development and peripheral survival. J Immunol. 2015;194:1677-85 pubmed 出版商
Silva J, Vetterlein O, Jose J, Peters S, Kirby H. The S228P mutation prevents in vivo and in vitro IgG4 Fab-arm exchange as demonstrated using a combination of novel quantitative immunoassays and physiological matrix preparation. J Biol Chem. 2015;290:5462-9 pubmed 出版商
Ramos Amaya A, Rodríguez Bayona B, López Blanco R, Andújar E, Pérez Alegre M, Campos Caro A, et al. Survival of human circulating antigen-induced plasma cells is supported by plasma cell-niche cytokines and T follicular helper lymphocytes. J Immunol. 2015;194:1031-8 pubmed 出版商
FLEENOR C, Rozhok A, Zaberezhnyy V, Mathew D, Kim J, Tan A, et al. Contrasting roles for C/EBPα and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects. Stem Cells. 2015;33:1345-58 pubmed 出版商
Bushkin Y, Radford F, Pine R, Lardizabal A, Mangura B, Gennaro M, et al. Profiling T cell activation using single-molecule fluorescence in situ hybridization and flow cytometry. J Immunol. 2015;194:836-41 pubmed 出版商
Bürgler S, Gimeno A, Parente Ribes A, Wang D, Os A, Devereux S, et al. Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism. J Immunol. 2015;194:827-35 pubmed 出版商
Park H, Huang X, Lu C, Cairo M, Zhou X. MicroRNA-146a and microRNA-146b regulate human dendritic cell apoptosis and cytokine production by targeting TRAF6 and IRAK1 proteins. J Biol Chem. 2015;290:2831-41 pubmed 出版商
Mota C, Nunes Silva V, Pires A, Matoso P, Victorino R, Sousa A, et al. Delta-like 1-mediated Notch signaling enhances the in vitro conversion of human memory CD4 T cells into FOXP3-expressing regulatory T cells. J Immunol. 2014;193:5854-62 pubmed 出版商
Belay E, Miller C, Kortum A, Torok Storb B, Blau C, Emery D. A hyperactive Mpl-based cell growth switch drives macrophage-associated erythropoiesis through an erythroid-megakaryocytic precursor. Blood. 2015;125:1025-33 pubmed 出版商
Yang D, Chen W, Xiong J, Sherrod C, Henry D, Dittmer D. Interleukin 1 receptor-associated kinase 1 (IRAK1) mutation is a common, essential driver for Kaposi sarcoma herpesvirus lymphoma. Proc Natl Acad Sci U S A. 2014;111:E4762-8 pubmed 出版商
Balmer M, Schürch C, Saito Y, Geuking M, Li H, Cuenca M, et al. Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling. J Immunol. 2014;193:5273-83 pubmed 出版商
Haemmerle R, Phaltane R, Rothe M, Schr xf6 der S, Schambach A, Moritz T, et al. Clonal Dominance With Retroviral Vector Insertions Near the ANGPT1 and ANGPT2 Genes in a Human Xenotransplant Mouse Model. Mol Ther Nucleic Acids. 2014;3:e200 pubmed 出版商
Stephen T, Rutkowski M, Allegrezza M, Perales Puchalt A, Tesone A, Svoronos N, et al. Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression. Immunity. 2014;41:427-439 pubmed 出版商
Dasgupta M, Unal H, Willard B, Yang J, Karnik S, Stark G. Critical role for lysine 685 in gene expression mediated by transcription factor unphosphorylated STAT3. J Biol Chem. 2014;289:30763-71 pubmed 出版商
Zdzieblo D, Li X, Lin Q, Zenke M, Illich D, Becker M, et al. Pcgf6, a polycomb group protein, regulates mesodermal lineage differentiation in murine ESCs and functions in iPS reprogramming. Stem Cells. 2014;32:3112-25 pubmed 出版商
Burton B, Britton G, Fang H, Verhagen J, Smithers B, Sabatos Peyton C, et al. Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy. Nat Commun. 2014;5:4741 pubmed 出版商
de Simone V, Franzè E, Ronchetti G, Colantoni A, Fantini M, Di Fusco D, et al. Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth. Oncogene. 2015;34:3493-503 pubmed 出版商
Gough D, Marié I, Lobry C, Aifantis I, Levy D. STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation. Blood. 2014;124:2252-61 pubmed 出版商
Yang Z, Augustin J, Chang C, Hu J, Shah K, Chang C, et al. The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells. Blood. 2014;124:2025-33 pubmed 出版商
Yu J, Wang Y, Yan F, Zhang P, Li H, Zhao H, et al. Noncanonical NF-?B activation mediates STAT3-stimulated IDO upregulation in myeloid-derived suppressor cells in breast cancer. J Immunol. 2014;193:2574-86 pubmed 出版商
Epaulard O, Adam L, Poux C, Zurawski G, Salabert N, Rosenbaum P, et al. Macrophage- and neutrophil-derived TNF-? instructs skin langerhans cells to prime antiviral immune responses. J Immunol. 2014;193:2416-26 pubmed 出版商
Wang C, Sather B, Wang X, Adair J, Khan I, Singh S, et al. Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells. Blood. 2014;124:913-23 pubmed 出版商
Genovese P, Schiroli G, Escobar G, Tomaso T, Firrito C, Calabria A, et al. Targeted genome editing in human repopulating haematopoietic stem cells. Nature. 2014;510:235-240 pubmed 出版商
Herr F, Lemoine R, Gouilleux F, Meley D, Kazma I, Heraud A, et al. IL-2 phosphorylates STAT5 to drive IFN-? production and activation of human dendritic cells. J Immunol. 2014;192:5660-70 pubmed 出版商
Ghamlouch H, Ouled Haddou H, Guyart A, Regnier A, Trudel S, Claisse J, et al. Phorbol myristate acetate, but not CD40L, induces the differentiation of CLL B cells into Ab-secreting cells. Immunol Cell Biol. 2014;92:591-604 pubmed 出版商
Wang D, Feng X, Lu L, Konkel J, Zhang H, Chen Z, et al. A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus. Arthritis Rheumatol. 2014;66:2234-45 pubmed 出版商
Nair S, Tomaras G, Sales A, Boczkowski D, Chan C, Plonk K, et al. High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes. Sci Rep. 2014;4:4632 pubmed 出版商
Nagashima H, Okuyama Y, Asao A, Kawabe T, Yamaki S, Nakano H, et al. The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6. Nat Immunol. 2014;15:449-56 pubmed 出版商
Berres M, Lim K, Peters T, Price J, Takizawa H, Salmon H, et al. BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups. J Exp Med. 2014;211:669-83 pubmed 出版商
Fan J, Zhang J, Dong L, Fu W, Du J, Shi H, et al. URI regulates tumorigenicity and chemotherapeutic resistance of multiple myeloma by modulating IL-6 transcription. Cell Death Dis. 2014;5:e1126 pubmed 出版商
Wu J, Yang J, Yang K, Wang H, Gorentla B, Shin J, et al. iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions. J Clin Invest. 2014;124:1685-98 pubmed 出版商
Kruspe S, Meyer C, Hahn U. Chlorin e6 Conjugated Interleukin-6 Receptor Aptamers Selectively Kill Target Cells Upon Irradiation. Mol Ther Nucleic Acids. 2014;3:e143 pubmed 出版商
Keiffer T, Bond J. Meprin metalloproteases inactivate interleukin 6. J Biol Chem. 2014;289:7580-8 pubmed 出版商
Nabekura T, Kanaya M, Shibuya A, Fu G, Gascoigne N, Lanier L. Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection. Immunity. 2014;40:225-34 pubmed 出版商
Bluteau D, Balduini A, Balayn N, Currao M, Nurden P, Deswarte C, et al. Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation. J Clin Invest. 2014;124:580-91 pubmed 出版商
Reichwald K, Jørgensen T, Tougaard P, Skov S. TL1A induces TCR independent IL-6 and TNF-? production and growth of PLZF? leukocytes. PLoS ONE. 2014;9:e85793 pubmed 出版商
Gupta S, Hirota M, Waugh S, Murakami I, Suzuki T, Muraguchi M, et al. Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor. J Biol Chem. 2014;289:8706-19 pubmed 出版商
Bots M, Verbrugge I, Martin B, Salmon J, Ghisi M, Baker A, et al. Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood. 2014;123:1341-52 pubmed 出版商
An B, Abbonante V, Yigit S, Balduini A, Kaplan D, Brodsky B. Definition of the native and denatured type II collagen binding site for fibronectin using a recombinant collagen system. J Biol Chem. 2014;289:4941-51 pubmed 出版商
Nievergall E, Ramshaw H, Yong A, Biondo M, Busfield S, Vairo G, et al. Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cells. Blood. 2014;123:1218-28 pubmed 出版商
Nold Petry C, Rudloff I, Baumer Y, Ruvo M, Marasco D, Botti P, et al. IL-32 promotes angiogenesis. J Immunol. 2014;192:589-602 pubmed 出版商
Velu C, Chaubey A, Phelan J, Horman S, Wunderlich M, Guzman M, et al. Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity. J Clin Invest. 2014;124:222-36 pubmed 出版商
Do J, Visperas A, Freeman M, Iwakura Y, Oukka M, Min B. Colitogenic effector T cells: roles of gut-homing integrin, gut antigen specificity and ?? T cells. Immunol Cell Biol. 2014;92:90-8 pubmed 出版商
Ho L, Yit P, Ng L, Linn Y, Zhao Y, Sun L, et al. The road to memory: an early rest for the long journey. J Immunol. 2013;191:5603-14 pubmed 出版商
Rodríguez Bayona B, Ramos Amaya A, López Blanco R, Campos Caro A, Brieva J. STAT-3 activation by differential cytokines is critical for human in vivo-generated plasma cell survival and Ig secretion. J Immunol. 2013;191:4996-5004 pubmed 出版商
Laperrousaz B, Jeanpierre S, Sagorny K, Voeltzel T, Ramas S, Kaniewski B, et al. Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression. Blood. 2013;122:3767-77 pubmed 出版商
Gong J, Yu J, Lin H, Zhang X, Yin X, Xiao Z, et al. The role, mechanism and potentially therapeutic application of microRNA-29 family in acute myeloid leukemia. Cell Death Differ. 2014;21:100-12 pubmed 出版商
Fernando J, Faber T, Pullen N, Falanga Y, Kolawole E, Oskeritzian C, et al. Genotype-dependent effects of TGF-?1 on mast cell function: targeting the Stat5 pathway. J Immunol. 2013;191:4505-13 pubmed 出版商
Casucci M, Nicolis Di Robilant B, Falcone L, Camisa B, Norelli M, Genovese P, et al. CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma. Blood. 2013;122:3461-72 pubmed 出版商
Ferreira E, Porter R, Wehling N, O Sullivan R, Liu F, Boskey A, et al. Inflammatory cytokines induce a unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. J Biol Chem. 2013;288:29494-505 pubmed 出版商
Fernandez I, Ooi T, Roy K. Generation of functional, antigen-specific CD8+ human T cells from cord blood stem cells using exogenous Notch and tetramer-TCR signaling. Stem Cells. 2014;32:93-104 pubmed 出版商
Richardson C, Delehanty L, Bullock G, Rival C, Tung K, KIMPEL D, et al. Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response. J Clin Invest. 2013;123:3614-23 pubmed 出版商
Liu Y, Yu S, Li Z, Ma J, Zhang Y, Wang H, et al. TGF-β enhanced IL-21-induced differentiation of human IL-21-producing CD4+ T cells via Smad3. PLoS ONE. 2013;8:e64612 pubmed 出版商
Subramanian H, Gupta K, Lee D, Bayir A, Ahn H, Ali H. β-Defensins activate human mast cells via Mas-related gene X2. J Immunol. 2013;191:345-52 pubmed 出版商
Wang S, Zhang X, Ju Y, Zhao B, Yan X, Hu J, et al. MicroRNA-146a feedback suppresses T cell immune function by targeting Stat1 in patients with chronic hepatitis B. J Immunol. 2013;191:293-301 pubmed 出版商
Kauskot A, Vandenbriele C, Louwette S, Gijsbers R, Tousseyn T, Freson K, et al. PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway. Blood. 2013;121:5208-17 pubmed 出版商
Li J, Wei B, Guo A, Liu C, Huang S, Du F, et al. Deficiency of ?-arrestin1 ameliorates collagen-induced arthritis with impaired TH17 cell differentiation. Proc Natl Acad Sci U S A. 2013;110:7395-400 pubmed 出版商
Long H, Chagoury O, Leese A, Ryan G, James E, Morton L, et al. MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response. J Exp Med. 2013;210:933-49 pubmed 出版商
Bolton Gillespie E, Schemionek M, Klein H, Flis S, Hoser G, Lange T, et al. Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells. Blood. 2013;121:4175-83 pubmed 出版商
Kajahn J, Franz S, Rueckert E, Forstreuter I, Hintze V, Moeller S, et al. Artificial extracellular matrices composed of collagen I and high sulfated hyaluronan modulate monocyte to macrophage differentiation under conditions of sterile inflammation. Biomatter. 2012;2:226-36 pubmed 出版商
McKimmie C, Singh M, Hewit K, Lopez Franco O, Le Brocq M, Rose John S, et al. An analysis of the function and expression of D6 on lymphatic endothelial cells. Blood. 2013;121:3768-77 pubmed 出版商
Harada Y, Inoue D, Ding Y, Imagawa J, Doki N, Matsui H, et al. RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes. Blood. 2013;121:3434-46 pubmed 出版商
Kotlarz D, Zietara N, Uzel G, Weidemann T, Braun C, Diestelhorst J, et al. Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome. J Exp Med. 2013;210:433-43 pubmed 出版商
Sportoletti P, Varasano E, Rossi R, Bereshchenko O, Cecchini D, Gionfriddo I, et al. The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model. Blood. 2013;121:3447-58 pubmed 出版商
Pick M, Azzola L, Osborne E, Stanley E, Elefanty A. Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium. PLoS ONE. 2013;8:e55530 pubmed 出版商
Luger R, Valookaran S, Knapp N, Vizzardelli C, Dohnal A, Felzmann T. Toll-like receptor 4 engagement drives differentiation of human and murine dendritic cells from a pro- into an anti-inflammatory mode. PLoS ONE. 2013;8:e54879 pubmed 出版商
Gao X, Lin J, Ning Q, Gao L, Yao Y, Zhou J, et al. A histone acetyltransferase p300 inhibitor C646 induces cell cycle arrest and apoptosis selectively in AML1-ETO-positive AML cells. PLoS ONE. 2013;8:e55481 pubmed 出版商
Xi J, Zhu H, Liu D, Nan X, Zheng W, Liu K, et al. Infusion of megakaryocytic progenitor products generated from cord blood hematopoietic stem/progenitor cells: results of the phase 1 study. PLoS ONE. 2013;8:e54941 pubmed 出版商
Touboul C, Lis R, Al Farsi H, Raynaud C, Warfa M, Althawadi H, et al. Mesenchymal stem cells enhance ovarian cancer cell infiltration through IL6 secretion in an amniochorionic membrane based 3D model. J Transl Med. 2013;11:28 pubmed 出版商
Currao M, Balduini C, Balduini A. High doses of romiplostim induce proliferation and reduce proplatelet formation by human megakaryocytes. PLoS ONE. 2013;8:e54723 pubmed 出版商
Lobry C, Ntziachristos P, Ndiaye Lobry D, Oh P, Cimmino L, Zhu N, et al. Notch pathway activation targets AML-initiating cell homeostasis and differentiation. J Exp Med. 2013;210:301-19 pubmed 出版商
Nair S, Aldrich A, McDonnell E, Cheng Q, Aggarwal A, Patel P, et al. Immunologic targeting of FOXP3 in inflammatory breast cancer cells. PLoS ONE. 2013;8:e53150 pubmed 出版商
Klco J, Spencer D, Lamprecht T, Sarkaria S, Wylie T, Magrini V, et al. Genomic impact of transient low-dose decitabine treatment on primary AML cells. Blood. 2013;121:1633-43 pubmed 出版商
Steinman R, Robinson A, Feghali Bostwick C. Antifibrotic effects of roscovitine in normal and scleroderma fibroblasts. PLoS ONE. 2012;7:e48560 pubmed 出版商
Braun D, Fribourg M, Sealfon S. Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation. J Biol Chem. 2013;288:2986-93 pubmed 出版商
Alysandratos K, Asadi S, Angelidou A, Zhang B, Sismanopoulos N, Yang H, et al. Neurotensin and CRH interactions augment human mast cell activation. PLoS ONE. 2012;7:e48934 pubmed 出版商
Westerberg C, H xe4 gglund H, Nilsson G. Proteasome inhibition upregulates Bim and induces caspase-3-dependent apoptosis in human mast cells expressing the Kit D816V mutation. Cell Death Dis. 2012;3:e417 pubmed 出版商
Waldmeier L, Meyer Schaller N, Diepenbruck M, Christofori G. Py2T murine breast cancer cells, a versatile model of TGF?-induced EMT in vitro and in vivo. PLoS ONE. 2012;7:e48651 pubmed 出版商
Kashiwakura J, Okayama Y, Furue M, Kabashima K, Shimada S, Ra C, et al. Most Highly Cytokinergic IgEs Have Polyreactivity to Autoantigens. Allergy Asthma Immunol Res. 2012;4:332-40 pubmed 出版商
Molinero L, Cubre A, Mora Solano C, Wang Y, Alegre M. T cell receptor/CARMA1/NF-?B signaling controls T-helper (Th) 17 differentiation. Proc Natl Acad Sci U S A. 2012;109:18529-34 pubmed 出版商
Bauer T, Zagorska A, Jurkin J, Yasmin N, Köffel R, Richter S, et al. Identification of Axl as a downstream effector of TGF-?1 during Langerhans cell differentiation and epidermal homeostasis. J Exp Med. 2012;209:2033-47 pubmed 出版商
Landsberg J, Kohlmeyer J, Renn M, Bald T, Rogava M, Cron M, et al. Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation. Nature. 2012;490:412-6 pubmed 出版商
Roy A, Cowan G, Mead A, Filippi S, Bohn G, Chaidos A, et al. Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21. Proc Natl Acad Sci U S A. 2012;109:17579-84 pubmed 出版商
Thiollier C, Lopez C, Gerby B, Ignacimouttou C, Poglio S, Duffourd Y, et al. Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models. J Exp Med. 2012;209:2017-31 pubmed 出版商
Yang T, Jian W, Luo Y, Fu X, NOGUCHI C, Bungert J, et al. Acetylation of histone deacetylase 1 regulates NuRD corepressor complex activity. J Biol Chem. 2012;287:40279-91 pubmed 出版商
Wang J, Xu K, Wu J, Luo C, Li Y, Wu X, et al. The changes of Th17 cells and the related cytokines in the progression of human colorectal cancers. BMC Cancer. 2012;12:418 pubmed 出版商
Vaeth M, Schliesser U, Müller G, Reissig S, Satoh K, Tuettenberg A, et al. Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A. 2012;109:16258-63 pubmed 出版商
Vatolin S, Khan S, Reu F. Direct chromatin PCR (DC-PCR): hypotonic conditions allow differentiation of chromatin states during thermal cycling. PLoS ONE. 2012;7:e44690 pubmed 出版商
Hodge L, Ziesmer S, Yang Z, Secreto F, Gertz M, Novak A, et al. IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia. Blood. 2012;120:3774-82 pubmed 出版商
Lee M, Lee J, Choi J, Lee C, Sim J, Cho C, et al. Interleukin-6 induces S100A9 expression in colonic epithelial cells through STAT3 activation in experimental ulcerative colitis. PLoS ONE. 2012;7:e38801 pubmed 出版商
Gori J, Chandrasekaran D, Kowalski J, Adair J, Beard B, D Souza S, et al. Efficient generation, purification, and expansion of CD34(+) hematopoietic progenitor cells from nonhuman primate-induced pluripotent stem cells. Blood. 2012;120:e35-44 pubmed
Arcipowski K, Bishop G. Roles of the kinase TAK1 in TRAF6-dependent signaling by CD40 and its oncogenic viral mimic, LMP1. PLoS ONE. 2012;7:e42478 pubmed 出版商
Khanna Gupta A, Abayasekara N, Levine M, Sun H, Virgilio M, Nia N, et al. Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein ? activity: implications in myelodysplastic syndrome and acute myeloid leukemia. J Biol Chem. 2012;287:32728-37 pubmed
Dass xe9 E, Volpe G, Walton D, Wilson N, Del Pozzo W, O Neill L, et al. Distinct regulation of c-myb gene expression by HoxA9, Meis1 and Pbx proteins in normal hematopoietic progenitors and transformed myeloid cells. Blood Cancer J. 2012;2:e76 pubmed 出版商
Tian F, Li J, Li Y, Luo S. Enhancement of myeloma development mediated though myeloma cell-Th2 cell interactions after microbial antigen presentation by myeloma cells and DCs. Blood Cancer J. 2012;2:e74 pubmed 出版商
Hansen N, xc5 gerstam H, Wahlestedt M, Landberg N, Askmyr M, Ehinger M, et al. SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function. Leukemia. 2013;27:130-5 pubmed 出版商
Buggele W, Johnson K, Horvath C. Influenza A virus infection of human respiratory cells induces primary microRNA expression. J Biol Chem. 2012;287:31027-40 pubmed 出版商
Gao H, Wu X, Sun Y, Zhou S, Silberstein L, Zhu Z. Suppression of homeobox transcription factor VentX promotes expansion of human hematopoietic stem/multipotent progenitor cells. J Biol Chem. 2012;287:29979-87 pubmed 出版商
Icardi L, Mori R, Gesellchen V, Eyckerman S, De Cauwer L, Verhelst J, et al. The Sin3a repressor complex is a master regulator of STAT transcriptional activity. Proc Natl Acad Sci U S A. 2012;109:12058-63 pubmed 出版商
Will B, Zhou L, Vogler T, Ben Neriah S, Schinke C, Tamari R, et al. Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations. Blood. 2012;120:2076-86 pubmed 出版商
Ekoff M, Lyberg K, Krajewska M, Arvidsson M, Rak S, Reed J, et al. Anti-apoptotic BFL-1 is the major effector in activation-induced human mast cell survival. PLoS ONE. 2012;7:e39117 pubmed 出版商
Nishishita N, Shikamura M, Takenaka C, Takada N, Fusaki N, Fusak N, et al. Generation of virus-free induced pluripotent stem cell clones on a synthetic matrix via a single cell subcloning in the naïve state. PLoS ONE. 2012;7:e38389 pubmed 出版商
Guo Z, Zhang H, Rao H, Jiang D, Cong X, Feng B, et al. DCs pulsed with novel HLA-A2-restricted CTL epitopes against hepatitis C virus induced a broadly reactive anti-HCV-specific T lymphocyte response. PLoS ONE. 2012;7:e38390 pubmed 出版商
Deng W, Lee J, Wang H, Miller J, Reik A, Gregory P, et al. Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell. 2012;149:1233-44 pubmed 出版商
Dao K, Rotelli M, Petersen C, Kaech S, Nelson W, Yates J, et al. FANCL ubiquitinates ?-catenin and enhances its nuclear function. Blood. 2012;120:323-34 pubmed 出版商
Yang J, Yang X, Li M. Baicalin, a natural compound, promotes regulatory T cell differentiation. BMC Complement Altern Med. 2012;12:64 pubmed 出版商
Asadi S, Theoharides T. Corticotropin-releasing hormone and extracellular mitochondria augment IgE-stimulated human mast-cell vascular endothelial growth factor release, which is inhibited by luteolin. J Neuroinflammation. 2012;9:85 pubmed 出版商
Lee H, Zhang P, Herrmann A, Yang C, Xin H, Wang Z, et al. Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation. Proc Natl Acad Sci U S A. 2012;109:7765-9 pubmed 出版商
Eaton A, Nagy E, Pacault M, Fauconnier J, Bäck M. Cysteinyl leukotriene signaling through perinuclear CysLT(1) receptors on vascular smooth muscle cells transduces nuclear calcium signaling and alterations of gene expression. J Mol Med (Berl). 2012;90:1223-31 pubmed 出版商
Ma C, Avery D, Chan A, Batten M, Bustamante J, Boisson Dupuis S, et al. Functional STAT3 deficiency compromises the generation of human T follicular helper cells. Blood. 2012;119:3997-4008 pubmed 出版商
Koguchi Y, Buenafe A, Thauland T, Gardell J, Bivins Smith E, Jacoby D, et al. Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+ 8- thymocytes and invariant NKT cells but not in Treg cells. PLoS ONE. 2012;7:e31296 pubmed 出版商
Tsuda K, Yamanaka K, Kitagawa H, Akeda T, Naka M, Niwa K, et al. Calcineurin inhibitors suppress cytokine production from memory T cells and differentiation of naïve T cells into cytokine-producing mature T cells. PLoS ONE. 2012;7:e31465 pubmed 出版商
Hulsmans M, Geeraert B, De Keyzer D, Mertens A, Lannoo M, Vanaudenaerde B, et al. Interleukin-1 receptor-associated kinase-3 is a key inhibitor of inflammation in obesity and metabolic syndrome. PLoS ONE. 2012;7:e30414 pubmed 出版商
Sangeetha V, Kadekar D, Kale V, Limaye L. Pharmacological inhibition of caspase and calpain proteases: a novel strategy to enhance the homing responses of cord blood HSPCs during expansion. PLoS ONE. 2012;7:e29383 pubmed 出版商
Kaufmann K, Gründer A, Hadlich T, Wehrle J, Gothwal M, Bogeska R, et al. A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2. J Exp Med. 2012;209:35-50 pubmed 出版商
Mack A, Kroboth S, Rajesh D, Wang W. Generation of induced pluripotent stem cells from CD34+ cells across blood drawn from multiple donors with non-integrating episomal vectors. PLoS ONE. 2011;6:e27956 pubmed 出版商
Subramanian H, Gupta K, Guo Q, Price R, Ali H. Mas-related gene X2 (MrgX2) is a novel G protein-coupled receptor for the antimicrobial peptide LL-37 in human mast cells: resistance to receptor phosphorylation, desensitization, and internalization. J Biol Chem. 2011;286:44739-49 pubmed 出版商
RÃ¥dinger M, Smrž D, Metcalfe D, Gilfillan A. Glycogen synthase kinase-3β is a prosurvival signal for the maintenance of human mast cell homeostasis. J Immunol. 2011;187:5587-95 pubmed 出版商
Jaako P, Flygare J, Olsson K, Quere R, Ehinger M, Henson A, et al. Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia. Blood. 2011;118:6087-96 pubmed 出版商
Sarma N, Yaseen N. Amino-terminal enhancer of split (AES) interacts with the oncoprotein NUP98-HOXA9 and enhances its transforming ability. J Biol Chem. 2011;286:38989-9001 pubmed 出版商
Ortner D, Grabher D, Hermann M, Kremmer E, Hofer S, Heufler C. The adaptor protein Bam32 in human dendritic cells participates in the regulation of MHC class I-induced CD8+ T cell activation. J Immunol. 2011;187:3972-8 pubmed 出版商
Harel E, Rubinstein A, Nissan A, Khazanov E, Nadler Milbauer M, Barenholz Y, et al. Enhanced transferrin receptor expression by proinflammatory cytokines in enterocytes as a means for local delivery of drugs to inflamed gut mucosa. PLoS ONE. 2011;6:e24202 pubmed 出版商
Badr G, Lefevre E, Mohany M. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis. PLoS ONE. 2011;6:e23741 pubmed 出版商
Mali R, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, et al. Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL. Cancer Cell. 2011;20:357-69 pubmed 出版商
Zhao M, Ma J, Zhu H, Zhang X, Du Z, Xu Y, et al. Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90. Mol Cancer. 2011;10:104 pubmed 出版商
Joha S, Nugues A, Hetuin D, Berthon C, Dezitter X, Dauphin V, et al. GILZ inhibits the mTORC2/AKT pathway in BCR-ABL(+) cells. Oncogene. 2012;31:1419-30 pubmed 出版商
Datta S, Hazari S, Chandra P, Samara M, Poat B, Gunduz F, et al. Mechanism of HCV's resistance to IFN-? in cell culture involves expression of functional IFN-? receptor 1. Virol J. 2011;8:351 pubmed 出版商
Sheng Z, Ma L, Sun J, Zhu L, Green M. BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription. Blood. 2011;118:2840-8 pubmed 出版商
Balduini A, Badalucco S, Pugliano M, Baev D, De Silvestri A, Cattaneo M, et al. In vitro megakaryocyte differentiation and proplatelet formation in Ph-negative classical myeloproliferative neoplasms: distinct patterns in the different clinical phenotypes. PLoS ONE. 2011;6:e21015 pubmed 出版商
Roy D, Sin S, Damania B, Dittmer D. Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines. Blood. 2011;118:e32-9 pubmed 出版商
Liang S, Yang X, Trieu Y, Li Z, Zive J, Leung Hagesteijn C, et al. Molecular target characterization and antimyeloma activity of the novel, insulin-like growth factor 1 receptor inhibitor, GTx-134. Clin Cancer Res. 2011;17:4693-704 pubmed 出版商
Melichar H, Li O, Ross J, Haber H, Cado D, Nolla H, et al. Comparative study of hematopoietic differentiation between human embryonic stem cell lines. PLoS ONE. 2011;6:e19854 pubmed 出版商
Ehlting C, Ronkina N, Böhmer O, Albrecht U, Bode K, Lang K, et al. Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulato. J Biol Chem. 2011;286:24113-24 pubmed 出版商
Jham B, Ma T, Hu J, Chaisuparat R, Friedman E, Pandolfi P, et al. Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma. PLoS ONE. 2011;6:e19103 pubmed 出版商
Migita K, Komori A, Torigoshi T, Maeda Y, Izumi Y, Jiuchi Y, et al. CP690,550 inhibits oncostatin M-induced JAK/STAT signaling pathway in rheumatoid synoviocytes. Arthritis Res Ther. 2011;13:R72 pubmed 出版商
von Rossum A, Krall R, Escalante N, Choy J. Inflammatory cytokines determine the susceptibility of human CD8 T cells to Fas-mediated activation-induced cell death through modulation of FasL and c-FLIP(S) expression. J Biol Chem. 2011;286:21137-44 pubmed 出版商
Lundequist A, Boyce J. LPA5 is abundantly expressed by human mast cells and important for lysophosphatidic acid induced MIP-1? release. PLoS ONE. 2011;6:e18192 pubmed 出版商
Elsawa S, Almada L, Ziesmer S, Novak A, Witzig T, Ansell S, et al. GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment. J Biol Chem. 2011;286:21524-34 pubmed 出版商
Hodge L, Novak A, Grote D, Braggio E, Ketterling R, Manske M, et al. Establishment and characterization of a novel Waldenstrom macroglobulinemia cell line, MWCL-1. Blood. 2011;117:e190-7 pubmed 出版商
Zou J, Sweeney C, Chou B, Choi U, Pan J, Wang H, et al. Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting. Blood. 2011;117:5561-72 pubmed 出版商
Yu J, Chau K, Vodyanik M, Jiang J, Jiang Y. Efficient feeder-free episomal reprogramming with small molecules. PLoS ONE. 2011;6:e17557 pubmed 出版商
Gibbs K, Gilbert P, Sachs K, Zhao F, Blau H, Weissman I, et al. Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments. Blood. 2011;117:4226-33 pubmed 出版商
Lu C, Huang X, Zhang X, Roensch K, Cao Q, Nakayama K, et al. miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1. Blood. 2011;117:4293-303 pubmed 出版商
Wang Z, Bishop E, Burke P. Expression profile analysis of the inflammatory response regulated by hepatocyte nuclear factor 4?. BMC Genomics. 2011;12:128 pubmed 出版商
Tanturli M, Giuntoli S, Barbetti V, Rovida E, Dello Sbarba P. Hypoxia selects bortezomib-resistant stem cells of chronic myeloid leukemia. PLoS ONE. 2011;6:e17008 pubmed 出版商
Wu X, Simpson J, Hong J, Kim K, Thavarajah N, Backx P, et al. MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutation. J Clin Invest. 2011;121:1009-25 pubmed 出版商
Chihara N, Aranami T, Sato W, Miyazaki Y, Miyake S, Okamoto T, et al. Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica. Proc Natl Acad Sci U S A. 2011;108:3701-6 pubmed 出版商
Liu F, Zhao X, Perna F, Wang L, Koppikar P, Abdel Wahab O, et al. JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell. 2011;19:283-94 pubmed 出版商
Hu K, Yu J, Suknuntha K, Tian S, Montgomery K, Choi K, et al. Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells. Blood. 2011;117:e109-19 pubmed 出版商
Bock C, Kiskinis E, Verstappen G, Gu H, Boulting G, Smith Z, et al. Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell. 2011;144:439-52 pubmed 出版商
Cheikh M, Magnin J, Gondrexon N, Willison J, Hassen A. Zinc and lead leaching from contaminated industrial waste sludges using coupled processes. Environ Technol. 2010;31:1577-85 pubmed 出版商
Sun H, Kapuria V, Peterson L, Fang D, Bornmann W, Bartholomeusz G, et al. Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis. Blood. 2011;117:3151-62 pubmed 出版商
Lu S, Li F, Yin H, Feng Q, Kimbrel E, Hahm E, et al. Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice. Cell Res. 2011;21:530-45 pubmed 出版商
Valeri A, Alonso Ferrero M, Rio P, Pujol M, Casado J, Perez L, et al. Bcr/Abl interferes with the Fanconi anemia/BRCA pathway: implications in the chromosomal instability of chronic myeloid leukemia cells. PLoS ONE. 2010;5:e15525 pubmed 出版商
Okano S, Yonemitsu Y, Shirabe K, Kakeji Y, Maehara Y, Harada M, et al. Provision of continuous maturation signaling to dendritic cells by RIG-I-stimulating cytosolic RNA synthesis of Sendai virus. J Immunol. 2011;186:1828-39 pubmed 出版商
Yeung J, Esposito M, Gandillet A, Zeisig B, Griessinger E, Bonnet D, et al. ?-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells. Cancer Cell. 2010;18:606-18 pubmed 出版商
Bosco M, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, et al. Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo. Blood. 2011;117:2625-39 pubmed 出版商
Nishimura K, Sano M, Ohtaka M, Furuta B, Umemura Y, Nakajima Y, et al. Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming. J Biol Chem. 2011;286:4760-71 pubmed 出版商
Chen T, Kambal A, Krysiak K, Walshauser M, Raju G, Tibbitts J, et al. Knockdown of Hspa9, a del(5q31.2) gene, results in a decrease in hematopoietic progenitors in mice. Blood. 2011;117:1530-9 pubmed 出版商
Fujimoto M, Nakano M, Terabe F, Kawahata H, Ohkawara T, Han Y, et al. The influence of excessive IL-6 production in vivo on the development and function of Foxp3+ regulatory T cells. J Immunol. 2011;186:32-40 pubmed 出版商
Gilbert L, Hemann M. DNA damage-mediated induction of a chemoresistant niche. Cell. 2010;143:355-66 pubmed 出版商
Bleck B, Tse D, Gordon T, Ahsan M, Reibman J. Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin. J Immunol. 2010;185:6636-45 pubmed 出版商
Berahovich R, Zabel B, Penfold M, Lewén S, Wang Y, Miao Z, et al. CXCR7 protein is not expressed on human or mouse leukocytes. J Immunol. 2010;185:5130-9 pubmed 出版商
Kis L, Gerasimcik N, Salamon D, Persson E, Nagy N, Klein G, et al. STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus-encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma. Blood. 2011;117:165-74 pubmed 出版商
Chessa T, Anderson K, Hu Y, Xu Q, Rausch O, Stephens L, et al. Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase. Blood. 2010;116:6027-36 pubmed 出版商
Zannetti C, Bonnay F, Takeshita F, Parroche P, Menetrier Caux C, Tommasino M, et al. C/EBP{delta} and STAT-1 are required for TLR8 transcriptional activity. J Biol Chem. 2010;285:34773-80 pubmed 出版商
V M S, Sangeetha V, Kale V, Limaye L. Expansion of cord blood CD34 cells in presence of zVADfmk and zLLYfmk improved their in vitro functionality and in vivo engraftment in NOD/SCID mouse. PLoS ONE. 2010;5:e12221 pubmed 出版商
Abdul Nabi A, Yassin E, Varghese N, Deshmukh H, Yaseen N. In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AML. PLoS ONE. 2010;5:e12464 pubmed 出版商
Thacker S, Berthier C, Mattinzoli D, Rastaldi M, Kretzler M, Kaplan M. The detrimental effects of IFN-? on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction. J Immunol. 2010;185:4457-69 pubmed 出版商
Zhang Q, Su W, Shi S, Wilder Smith P, Xiang A, Wong A, et al. Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing. Stem Cells. 2010;28:1856-68 pubmed 出版商
Purvis H, Stoop J, Mann J, Woods S, Kozijn A, Hambleton S, et al. Low-strength T-cell activation promotes Th17 responses. Blood. 2010;116:4829-37 pubmed 出版商
Skorokhod O, Caione L, Marrocco T, Migliardi G, Barrera V, Arese P, et al. Inhibition of erythropoiesis in malaria anemia: role of hemozoin and hemozoin-generated 4-hydroxynonenal. Blood. 2010;116:4328-37 pubmed 出版商
Jensen S, Gad M. Differential induction of inflammatory cytokines by dendritic cells treated with novel TLR-agonist and cytokine based cocktails: targeting dendritic cells in autoimmunity. J Inflamm (Lond). 2010;7:37 pubmed 出版商
Buono M, Visigalli I, Bergamasco R, Biffi A, Cosma M. Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development. J Exp Med. 2010;207:1647-60 pubmed 出版商
Karlberg M, Ekoff M, Huang D, Mustonen P, Harvima I, Nilsson G. The BH3-mimetic ABT-737 induces mast cell apoptosis in vitro and in vivo: potential for therapeutics. J Immunol. 2010;185:2555-62 pubmed 出版商
Grassinger J, Haylock D, Williams B, Olsen G, Nilsson S. Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential. Blood. 2010;116:3185-96 pubmed 出版商
Yeh N, Glosson N, Wang N, Guindon L, McKinley C, Hamada H, et al. Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype. J Immunol. 2010;185:2089-98 pubmed 出版商
Perna F, Gurvich N, Hoya Arias R, Abdel Wahab O, Levine R, Asai T, et al. Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera. Blood. 2010;116:2812-21 pubmed 出版商
Kuang D, Peng C, Zhao Q, Wu Y, Zhu L, Wang J, et al. Tumor-activated monocytes promote expansion of IL-17-producing CD8+ T cells in hepatocellular carcinoma patients. J Immunol. 2010;185:1544-9 pubmed 出版商
Bill M, Fuchs J, Li C, Yui J, Bakan C, Benson D, et al. The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Mol Cancer. 2010;9:165 pubmed 出版商
Felli N, Cianetti L, Pelosi E, Carè A, Liu C, Calin G, et al. Hematopoietic differentiation: a coordinated dynamical process towards attractor stable states. BMC Syst Biol. 2010;4:85 pubmed 出版商
Knipe L, Meli A, Hewlett L, Bierings R, Dempster J, Skehel P, et al. A revised model for the secretion of tPA and cytokines from cultured endothelial cells. Blood. 2010;116:2183-91 pubmed 出版商
Halene S, Gao Y, Hahn K, Massaro S, Italiano J, Schulz V, et al. Serum response factor is an essential transcription factor in megakaryocytic maturation. Blood. 2010;116:1942-50 pubmed 出版商
Zhang Y, Tang W, Jones M, Xu W, Halene S, Wu D. Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils. J Biol Chem. 2010;285:24805-14 pubmed 出版商
Cheng H, Su S, Huang L, Hsieh B, Hu Y, Hung T, et al. Arecoline induces HA22T/VGH hepatoma cells to undergo anoikis - involvement of STAT3 and RhoA activation. Mol Cancer. 2010;9:126 pubmed 出版商
Huang C, Yang G, Jiang T, Huang K, Cao J, Qiu Z. Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro. J Exp Clin Cancer Res. 2010;29:51 pubmed 出版商
Yu L, Ji W, Zhang H, Renda M, He Y, Lin S, et al. SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis. J Exp Med. 2010;207:1183-95 pubmed 出版商
Chang Y, Hua W, Yao C, Hwang S, Hung Y, Kuan C, et al. Protein-arginine methyltransferase 1 suppresses megakaryocytic differentiation via modulation of the p38 MAPK pathway in K562 cells. J Biol Chem. 2010;285:20595-606 pubmed 出版商
Burgler S, Mantel P, Bassin C, Ouaked N, Akdis C, Schmidt Weber C. RORC2 is involved in T cell polarization through interaction with the FOXP3 promoter. J Immunol. 2010;184:6161-9 pubmed 出版商
Yu C, Liu Y, Miao Z, Yin M, Lu W, Lv Y, et al. Retinoic acid enhances the generation of hematopoietic progenitors from human embryonic stem cell-derived hemato-vascular precursors. Blood. 2010;116:4786-94 pubmed 出版商
Chen T, Koga K, Li X, Zhuo M. Spinal microglial motility is independent of neuronal activity and plasticity in adult mice. Mol Pain. 2010;6:19 pubmed 出版商
Jurkin J, Schichl Y, Koeffel R, Bauer T, Richter S, Konradi S, et al. miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation. J Immunol. 2010;184:4955-65 pubmed 出版商
Singbrant S, Karlsson G, Ehinger M, Olsson K, Jaako P, Miharada K, et al. Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture. Blood. 2010;115:4689-98 pubmed 出版商
Giorgetti A, Montserrat N, Rodriguez Piza I, Azqueta C, Veiga A, Izpisua Belmonte J. Generation of induced pluripotent stem cells from human cord blood cells with only two factors: Oct4 and Sox2. Nat Protoc. 2010;5:811-20 pubmed 出版商
Niyonsaba F, Ushio H, Hara M, Yokoi H, Tominaga M, Takamori K, et al. Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells. J Immunol. 2010;184:3526-34 pubmed 出版商
Kataoka T, Kumanogoh A, Bandara G, Metcalfe D, Gilfillan A. CD72 negatively regulates KIT-mediated responses in human mast cells. J Immunol. 2010;184:2468-75 pubmed 出版商
Fratini P, Strauss B. Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector. Virol J. 2010;7:16 pubmed 出版商
Valmas C, Grosch M, Schumann M, Olejnik J, Martinez O, Best S, et al. Marburg virus evades interferon responses by a mechanism distinct from ebola virus. PLoS Pathog. 2010;6:e1000721 pubmed 出版商
Kis L, Salamon D, Persson E, Nagy N, Scheeren F, Spits H, et al. IL-21 imposes a type II EBV gene expression on type III and type I B cells by the repression of C- and activation of LMP-1-promoter. Proc Natl Acad Sci U S A. 2010;107:872-7 pubmed 出版商
RÃ¥dinger M, Kuehn H, Kim M, Metcalfe D, Gilfillan A. Glycogen synthase kinase 3beta activation is a prerequisite signal for cytokine production and chemotaxis in human mast cells. J Immunol. 2010;184:564-72 pubmed 出版商
Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, et al. Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property. J Immunol. 2009;183:8176-85 pubmed 出版商
Robert G, Ben Sahra I, Puissant A, Colosetti P, Belhacene N, Gounon P, et al. Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death. PLoS ONE. 2009;4:e7889 pubmed 出版商
Zhang Q, Yamaza T, Kelly A, Shi S, Wang S, Brown J, et al. Tumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axis. PLoS ONE. 2009;4:e7798 pubmed 出版商
Pelletier M, Maggi L, Micheletti A, Lazzeri E, Tamassia N, Costantini C, et al. Evidence for a cross-talk between human neutrophils and Th17 cells. Blood. 2010;115:335-43 pubmed 出版商
Jansson L, Larsson J. W41/W41 blastocyst complementation: a system for genetic modeling of hematopoiesis. Blood. 2010;115:47-50 pubmed 出版商
Aichberger K, Gleixner K, Mirkina I, Cerny Reiterer S, Peter B, Ferenc V, et al. Identification of proapoptotic Bim as a tumor suppressor in neoplastic mast cells: role of KIT D816V and effects of various targeted drugs. Blood. 2009;114:5342-51 pubmed 出版商
McGillicuddy F, Chiquoine E, Hinkle C, Kim R, Shah R, Roche H, et al. Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway. J Biol Chem. 2009;284:31936-44 pubmed 出版商
Zsiros E, Kis Toth K, Hajdu P, Gaspar R, Bielanska J, Felipe A, et al. Developmental switch of the expression of ion channels in human dendritic cells. J Immunol. 2009;183:4483-92 pubmed 出版商
Tsukamoto N, Okada S, Onami Y, Sasaki Y, Umezawa K, Kawakami Y. Impairment of plasmacytoid dendritic cells for IFN production by the ligand for immunoglobulin-like transcript 7 expressed on human cancer cells. Clin Cancer Res. 2009;15:5733-43 pubmed 出版商
Ma C, Suryani S, Avery D, Chan A, Nanan R, Santner Nanan B, et al. Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12. Immunol Cell Biol. 2009;87:590-600 pubmed 出版商
Tian X, Hexum M, Penchev V, Taylor R, Shultz L, Kaufman D. Bioluminescent imaging demonstrates that transplanted human embryonic stem cell-derived CD34(+) cells preferentially develop into endothelial cells. Stem Cells. 2009;27:2675-85 pubmed 出版商
Will B, Kawahara M, Luciano J, Bruns I, Parekh S, Erickson Miller C, et al. Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome. Blood. 2009;114:3899-908 pubmed 出版商
Hatzistavrou T, Micallef S, Ng E, Vadolas J, Stanley E, Elefanty A. ErythRED, a hESC line enabling identification of erythroid cells. Nat Methods. 2009;6:659-62 pubmed 出版商
Oehler V, Guthrie K, Cummings C, Sabo K, Wood B, Gooley T, et al. The preferentially expressed antigen in melanoma (PRAME) inhibits myeloid differentiation in normal hematopoietic and leukemic progenitor cells. Blood. 2009;114:3299-308 pubmed 出版商
Hagn M, Schwesinger E, Ebel V, Sontheimer K, Maier J, Beyer T, et al. Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21. J Immunol. 2009;183:1838-45 pubmed 出版商
Eberhard Y, McDermott S, Wang X, Gronda M, Venugopal A, Wood T, et al. Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells. Blood. 2009;114:3064-73 pubmed 出版商
Schwieger M, Schuler A, Forster M, Engelmann A, Arnold M, Delwel R, et al. Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C. Blood. 2009;114:2476-88 pubmed 出版商
Kandilci A, Grosveld G. Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyperproliferation and restores myeloid differentiation. Blood. 2009;114:1596-606 pubmed 出版商
Zhu P, Liu X, Treml L, Cancro M, Freedman B. Mechanism and regulatory function of CpG signaling via scavenger receptor B1 in primary B cells. J Biol Chem. 2009;284:22878-87 pubmed 出版商
Hegde S, Jankowska Gan E, Roenneburg D, Torrealba J, Burlingham W, Gumperz J. Human NKT cells promote monocyte differentiation into suppressive myeloid antigen-presenting cells. J Leukoc Biol. 2009;86:757-68 pubmed 出版商
Kato A, Chustz R, Ogasawara T, Kulka M, Saito H, Schleimer R, et al. Dexamethasone and FK506 inhibit expression of distinct subsets of chemokines in human mast cells. J Immunol. 2009;182:7233-43 pubmed 出版商
Boehmler A, Drost A, Jaggy L, Seitz G, Wiesner T, Denzlinger C, et al. The CysLT1 ligand leukotriene D4 supports alpha4beta1- and alpha5beta1-mediated adhesion and proliferation of CD34+ hematopoietic progenitor cells. J Immunol. 2009;182:6789-98 pubmed 出版商
Bautista J, Lio C, Lathrop S, Forbush K, Liang Y, Luo J, et al. Intraclonal competition limits the fate determination of regulatory T cells in the thymus. Nat Immunol. 2009;10:610-7 pubmed 出版商
Sundstrom J, Hair G, Ansari A, Secor W, Gilfillan A, Metcalfe D, et al. IgE-FcepsilonRI interactions determine HIV coreceptor usage and susceptibility to infection during ontogeny of mast cells. J Immunol. 2009;182:6401-9 pubmed 出版商
Jin W, Zhou X, Yu J, Cheng X, Sun S. Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK. Blood. 2009;113:6603-10 pubmed 出版商
Chung Y, Chang S, Martinez G, Yang X, Nurieva R, Kang H, et al. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity. 2009;30:576-87 pubmed 出版商
La Rocca R, Fulciniti M, Lakshmikanth T, Mesuraca M, Ali T, Mazzei V, et al. Early hematopoietic zinc finger protein prevents tumor cell recognition by natural killer cells. J Immunol. 2009;182:4529-37 pubmed 出版商
Thompson B, Mazurkiewicz Munoz A, Suttles J, Carter Su C, Bernlohr D. Interaction of adipocyte fatty acid-binding protein (AFABP) and JAK2: AFABP/aP2 as a regulator of JAK2 signaling. J Biol Chem. 2009;284:13473-80 pubmed 出版商
Chong H, Tan M, Philippe V, Tan S, Tan C, Ku C, et al. Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing. J Cell Biol. 2009;184:817-31 pubmed 出版商
Ford A, Palmi C, Bueno C, Hong D, Cardus P, Knight D, et al. The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells. J Clin Invest. 2009;119:826-36 pubmed 出版商
Horiuchi Y, Onodera M, Miyagawa Y, Sato B, Onda K, Katagiri Y, et al. Kinetics and effect of integrin expression on human CD34(+) cells during murine leukemia virus-derived retroviral transduction with recombinant fibronectin for stem cell gene therapy. Hum Gene Ther. 2009;20:777-83 pubmed 出版商
Qu C, Nguyen V, Merad M, Randolph G. MHC class I/peptide transfer between dendritic cells overcomes poor cross-presentation by monocyte-derived APCs that engulf dying cells. J Immunol. 2009;182:3650-9 pubmed 出版商
Nurieva R, Yang X, Chung Y, Dong C. Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts. J Immunol. 2009;182:2565-8 pubmed 出版商
Eberl M, Roberts G, Meuter S, Williams J, Topley N, Moser B. A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections. PLoS Pathog. 2009;5:e1000308 pubmed 出版商
Szeles L, Keresztes G, Torocsik D, Balajthy Z, Krenacs L, Poliska S, et al. 1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype. J Immunol. 2009;182:2074-83 pubmed 出版商
Vagima Y, Avigdor A, Goichberg P, Shivtiel S, Tesio M, Kalinkovich A, et al. MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization. J Clin Invest. 2009;119:492-503 pubmed 出版商
Helmy A, Carpenter K, Skepper J, Kirkpatrick P, Pickard J, Hutchinson P. Microdialysis of cytokines: methodological considerations, scanning electron microscopy, and determination of relative recovery. J Neurotrauma. 2009;26:549-61 pubmed 出版商
Saadatzadeh M, Bijangi Vishehsaraei K, Kapur R, Haneline L. Distinct roles of stress-activated protein kinases in Fanconi anemia-type C-deficient hematopoiesis. Blood. 2009;113:2655-60 pubmed 出版商
Fukushima K, Matsumura I, Ezoe S, Tokunaga M, Yasumi M, Satoh Y, et al. FIP1L1-PDGFRalpha imposes eosinophil lineage commitment on hematopoietic stem/progenitor cells. J Biol Chem. 2009;284:7719-32 pubmed 出版商
Cheng E, Luo Q, Bruscia E, Renda M, Troy J, Massaro S, et al. Role for MKL1 in megakaryocytic maturation. Blood. 2009;113:2826-34 pubmed 出版商
Bauler T, Hendriks W, King P. The FERM and PDZ domain-containing protein tyrosine phosphatases, PTPN4 and PTPN3, are both dispensable for T cell receptor signal transduction. PLoS ONE. 2008;3:e4014 pubmed 出版商
Soriani A, Zingoni A, Cerboni C, Iannitto M, Ricciardi M, Di Gialleonardo V, et al. ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype. Blood. 2009;113:3503-11 pubmed 出版商
Compte M, Cuesta A, Sánchez Martín D, Alonso Camino V, Vicario J, Sanz L, et al. Tumor immunotherapy using gene-modified human mesenchymal stem cells loaded into synthetic extracellular matrix scaffolds. Stem Cells. 2009;27:753-60 pubmed 出版商
Ando T, Mimura K, Johansson C, Hanson M, Mougiakakos D, Larsson C, et al. Transduction with the antioxidant enzyme catalase protects human T cells against oxidative stress. J Immunol. 2008;181:8382-90 pubmed
Bansal G, DiVietro J, Kuehn H, Rao S, Nocka K, Gilfillan A, et al. RGS13 controls g protein-coupled receptor-evoked responses of human mast cells. J Immunol. 2008;181:7882-90 pubmed
Kuehn H, Swindle E, Kim M, Beaven M, Metcalfe D, Gilfillan A. The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells. J Immunol. 2008;181:7706-12 pubmed
Hikata T, Takaishi H, Takito J, Hakozaki A, Furukawa M, Uchikawa S, et al. PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts. Blood. 2009;113:2202-12 pubmed 出版商
Okumura S, Yuki K, Kobayashi R, Okamura S, Ohmori K, Saito H, et al. Hyperexpression of NOD2 in intestinal mast cells of Crohn's disease patients: preferential expression of inflammatory cell-recruiting molecules via NOD2 in mast cells. Clin Immunol. 2009;130:175-85 pubmed 出版商
Moschen A, Geiger S, Krehan I, Kaser A, Tilg H. Interferon-alpha controls IL-17 expression in vitro and in vivo. Immunobiology. 2008;213:779-87 pubmed 出版商
Saeki K, Saeki K, Nakahara M, Matsuyama S, Nakamura N, Yogiashi Y, et al. A feeder-free and efficient production of functional neutrophils from human embryonic stem cells. Stem Cells. 2009;27:59-67 pubmed 出版商
Moldenhauer A, Genter G, Lun A, Bal G, Kiesewetter H, Salama A. Hematopoietic progenitor cells and interleukin-stimulated endothelium: expansion and differentiation of myeloid precursors. BMC Immunol. 2008;9:56 pubmed 出版商
Nelson E, Walker S, Kepich A, Gashin L, Hideshima T, Ikeda H, et al. Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3. Blood. 2008;112:5095-102 pubmed 出版商
Kalwitz G, Endres M, Neumann K, Skriner K, Ringe J, Sezer O, et al. Gene expression profile of adult human bone marrow-derived mesenchymal stem cells stimulated by the chemokine CXCL7. Int J Biochem Cell Biol. 2009;41:649-58 pubmed 出版商
Kirshenbaum A, Swindle E, Kulka M, Wu Y, Metcalfe D. Effect of lipopolysaccharide (LPS) and peptidoglycan (PGN) on human mast cell numbers, cytokine production, and protease composition. BMC Immunol. 2008;9:45 pubmed 出版商
Bradshaw E, Kent S, Tripuraneni V, Orban T, Ploegh H, Hafler D, et al. Concurrent detection of secreted products from human lymphocytes by microengraving: cytokines and antigen-reactive antibodies. Clin Immunol. 2008;129:10-8 pubmed 出版商
Johansson S, Price J, Modo M. Effect of inflammatory cytokines on major histocompatibility complex expression and differentiation of human neural stem/progenitor cells. Stem Cells. 2008;26:2444-54 pubmed 出版商
Ma C, Chew G, Simpson N, Priyadarshi A, Wong M, Grimbacher B, et al. Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3. J Exp Med. 2008;205:1551-7 pubmed 出版商
Takagi R, Higashi T, Hashimoto K, Nakano K, Mizuno Y, Okazaki Y, et al. B cell chemoattractant CXCL13 is preferentially expressed by human Th17 cell clones. J Immunol. 2008;181:186-9 pubmed
Hu Y, Hu X, Boumsell L, Ivashkiv L. IFN-gamma and STAT1 arrest monocyte migration and modulate RAC/CDC42 pathways. J Immunol. 2008;180:8057-65 pubmed
Tanaka Y, Tanaka N, Saeki Y, Tanaka K, Murakami M, Hirano T, et al. c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130. Mol Cell Biol. 2008;28:4805-18 pubmed 出版商
Takayama N, Nishikii H, Usui J, Tsukui H, Sawaguchi A, Hiroyama T, et al. Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors. Blood. 2008;111:5298-306 pubmed 出版商
Seita J, Asakawa M, Ooehara J, Takayanagi S, Morita Y, Watanabe N, et al. Interleukin-27 directly induces differentiation in hematopoietic stem cells. Blood. 2008;111:1903-12 pubmed
Ziesch xe9 E, Bachmann M, Kleinert H, Pfeilschifter J, M xfc hl H. The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells. J Biol Chem. 2007;282:16006-15 pubmed
Rigby R, Simmons J, Greenhalgh C, Alexander W, Lund P. Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon. Oncogene. 2007;26:4833-41 pubmed
Khanna Gupta A, Sun H, Zibello T, Lee H, Dahl R, Boxer L, et al. Growth factor independence-1 (Gfi-1) plays a role in mediating specific granule deficiency (SGD) in a patient lacking a gene-inactivating mutation in the C/EBPepsilon gene. Blood. 2007;109:4181-90 pubmed
Bauer A, Villunger A, Labi V, Fischer S, Strasser A, Wagner H, et al. The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells. Proc Natl Acad Sci U S A. 2006;103:10979-84 pubmed
Wong P, Egan P, Croker B, O Donnell K, Sims N, Drake S, et al. SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis. J Clin Invest. 2006;116:1571-81 pubmed
Gonzalez Garcia I, Ocana E, Jiménez Gómez G, Campos Caro A, Brieva J. Immunization-induced perturbation of human blood plasma cell pool: progressive maturation, IL-6 responsiveness, and high PRDI-BF1/BLIMP1 expression are critical distinctions between antigen-specific and nonspecific plasma cells. J Immunol. 2006;176:4042-50 pubmed
Silverman J, Liu Q, Lu Q, Bakker A, To W, Duguay A, et al. Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains. Nat Biotechnol. 2005;23:1556-61 pubmed
Munitz A, Bachelet I, Eliashar R, Moretta A, Moretta L, Levi Schaffer F. The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils. Blood. 2006;107:1996-2003 pubmed
Weller C, Collington S, Brown J, Miller H, Al Kashi A, Clark P, et al. Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors. J Exp Med. 2005;201:1961-71 pubmed
van Beek J, van Meurs M, t Hart B, Brok H, Neal J, Chatagner A, et al. Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation. J Immunol. 2005;174:2353-65 pubmed
Morris G, Whyte M, Martin G, Jose P, Dower S, Sabroe I. Agonists of toll-like receptors 2 and 4 activate airway smooth muscle via mononuclear leukocytes. Am J Respir Crit Care Med. 2005;171:814-22 pubmed
Lin L, Gerth A, Peng S. Active inhibition of plasma cell development in resting B cells by microphthalmia-associated transcription factor. J Exp Med. 2004;200:115-22 pubmed
Hemminki A, Kanerva A, Liu B, Wang M, Alvarez R, Siegal G, et al. Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression. Cancer Res. 2003;63:847-53 pubmed
Guo X, Chandrasekaran V, Lein P, Kaplan P, Higgins D. Leukemia inhibitory factor and ciliary neurotrophic factor cause dendritic retraction in cultured rat sympathetic neurons. J Neurosci. 1999;19:2113-21 pubmed
产品信息
产品类型 :
蛋白
产品名称 :
Human IL-6 Recombinant Protein, PeproTech
目录# :
200-06微克
规格 :
100微克
价格 :
美国648.00
克隆性 :
重组
纯度 :
HPLC, 十二烷基磺酸钠-PAGE
反应物种 :
人类
应用 :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
物种 :
人类
储存 :
-20°C
描述 :
IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
格式 :
冻干
应用w/稀释 :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
别名 :
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国