产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD11b (activation epitope) Monoclonal Antibody (CBRM1/5), PE-Cyanine7, eBioscience™
目录 :
25-0113-42
规格 :
100试验
价格 :
美国333
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE/Cy7
克隆名称 :
CBRM1/5
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 10
参考文献
Kraft J, Blomgran R, Bergstr xf6 m I, Sot xe1 k M, Clark M, Rani A, et al. Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis. FASEB J. 2022;36:e22173 pubmed 出版商
Xu W, Li S, Li M, Zhou H, Yang X. Upregulation of CD3ζ and L-selectin in antigen-specific cytotoxic T lymphocytes by eliminating myeloid-derived suppressor cells with doxorubicin to improve killing efficacy of neuroblastoma cells in vitro. J Clin Lab Anal. 2022;36:e24158 pubmed 出版商
Yao J, Zhong L, Zhong P, Liu D, Yuan Z, Liu J, et al. RAS-Responsive Element-Binding Protein 1 Blocks the Granulocytic Differentiation of Myeloid Leukemia Cells. Oncol Res. 2019;27:809-818 pubmed 出版商
Li D, Liu W, Wang G, Shi X. Impact of combined ischemic preconditioning and remote ischemic perconditioning on ischemia-reperfusion injury after liver transplantation. Sci Rep. 2018;8:17979 pubmed 出版商
He L, Fu Y, Deng J, Shen Y, Wang Y, Yu F, et al. Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development. Arterioscler Thromb Vasc Biol. 2018;38:1616-1631 pubmed 出版商
Song H, Li L, Zhong L, Yang R, Jiang K, Yang X, et al. NLS?RAR? modulates acute promyelocytic leukemia NB4 cell proliferation and differentiation via the PI3K/AKT pathway. Mol Med Rep. 2016;14:5495-5500 pubmed 出版商
Zhu N, Wang H, Wang B, Wei J, Shan W, Feng J, et al. A Member of the Nuclear Receptor Superfamily, Designated as NR2F2, Supports the Self-Renewal Capacity and Pluripotency of Human Bone Marrow-Derived Mesenchymal Stem Cells. Stem Cells Int. 2016;2016:5687589 pubmed 出版商
Chen J, Han L, Xu X, Tang H, Wang H, Wei B. Serum biomarkers VEGF-C and IL-6 are associated with severe human Peripheral Artery Stenosis. J Inflamm (Lond). 2015;12:50 pubmed 出版商
Zeng C, Chen Z, Zhang X, Han B, Lin K, Li X, et al. MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy-lysosomal pathway in acute promyelocytic leukemia. Autophagy. 2014;10:1726-37 pubmed 出版商
Yan T, Li Q, Zhou H, Zhao Y, Yu S, Xu G, et al. Gu-4 suppresses affinity and avidity modulation of CD11b and improves the outcome of mice with endotoxemia and sepsis. PLoS ONE. 2012;7:e30110 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD11b (activation epitope) Monoclonal Antibody (CBRM1/5), PE-Cyanine7, eBioscience™
目录# :
25-0113-42
规格 :
100试验
价格 :
美国333
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µL (0.06 µg)/test
物种 :
人类
克隆 :
CBRM1/5
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.06 µg)/test
别名 :
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); Itgam; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国