产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD19 Monoclonal Antibody (eBio1D3 (1D3)), PE-Cyanine7, eBioscience
目录 :
25-0193-81
规格 :
50微克
价格 :
美国119
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE/Cy7
克隆名称 :
eBio1D3(1D3)
反应物种 :
人类, 小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 176
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:100; 图 2s1g
Glassman C, Su L, Majri Morrison S, Winkelmann H, Mo F, Li P, et al. Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist. elife. 2021;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Yen W, Sharma R, Cols M, Lau C, Chaudhry A, Chowdhury P, et al. Distinct Requirements of CHD4 during B Cell Development and Antibody Response. Cell Rep. 2019;27:1472-1486.e5 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400; 图 8c
Glal D, Sudhakar J, Lu H, Liu M, Chiang H, Liu Y, et al. ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases. Front Immunol. 2018;9:2522 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 5a
Vigolo M, Chambers M, Willen L, Chevalley D, Maskos K, Lammens A, et al. A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors. Nat Commun. 2018;9:1199 pubmed 出版商
  • 流式细胞仪; 人类; 图 1e
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  • 流式细胞仪; 小鼠; 1:200; 表 1
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  • 流式细胞仪; 小鼠; 1:200; 图 s5
Haemmerle M, Bottsford Miller J, Pradeep S, Taylor M, Choi H, Hansen J, et al. FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. J Clin Invest. 2016;126:1885-96 pubmed 出版商
  • 流式细胞仪; 小鼠
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  • 流式细胞仪; 小鼠
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  • 流式细胞仪; 小鼠
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  • 流式细胞仪; 小鼠
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Li C, Wang H, Georgakopoulou A, Gil S, Yannaki E, Lieber A. In Vivo HSC Gene Therapy Using a Bi-modular HDAd5/35++ Vector Cures Sickle Cell Disease in a Mouse Model. Mol Ther. 2021;29:822-837 pubmed 出版商
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Shen T, Chen C, Jhan M, Tseng P, Lin C. CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain. Front Cell Infect Microbiol. 2020;10:557610 pubmed 出版商
Zhao A, Shah K, Freitag J, Cromer B, Sumer H. Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia. Stem Cells Int. 2020;2020:8898221 pubmed 出版商
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Wijewarnasuriya D, Bebernitz C, Lopez A, Rafiq S, Brentjens R. Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells. Cancer Immunol Res. 2020;8:732-742 pubmed 出版商
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Schuepbach Mallepell S, Das D, Willen L, Vigolo M, Tardivel A, Lebon L, et al. Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties. J Biol Chem. 2015;290:16330-42 pubmed 出版商
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Wong T, Doyle A, Lee J, Jelinek D. Eosinophils regulate peripheral B cell numbers in both mice and humans. J Immunol. 2014;192:3548-58 pubmed 出版商
Pinhu L, Qin Y, Xiong B, You Y, Li J, Sooranna S. Overexpression of Fas and FasL is associated with infectious complications and severity of experimental severe acute pancreatitis by promoting apoptosis of lymphocytes. Inflammation. 2014;37:1202-12 pubmed 出版商
Racine J, Wang M, Zhang M, Zeng D. Induction of mixed chimerism depletes pre-existing and de novo-developed autoreactive B cells in autoimmune NOD mice. Diabetes. 2014;63:2051-62 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD19 Monoclonal Antibody (eBio1D3 (1D3)), PE-Cyanine7, eBioscience
目录# :
25-0193-81
规格 :
50微克
价格 :
美国119
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test
物种 :
小鼠
克隆 :
eBio1D3(1D3)
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test
别名 :
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国