产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD20 Monoclonal Antibody (2H7), PE-Cyanine7, eBioscience
目录 :
25-0209-42
规格 :
100试验
价格 :
美国346
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE/Cy7
克隆名称 :
2H7
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 7b
Zhu H, Hu F, Sun X, Zhang X, Zhu L, Liu X, et al. CD16+ Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus. Front Immunol. 2016;7:512 pubmed
Chen C, Huang X, Zhu W, Ding C, Huang P, Li R. TRPA1 triggers hyperalgesia and inflammation after tooth bleaching. Sci Rep. 2021;11:17418 pubmed 出版商
Jankeel A, Menicucci A, Woolsey C, Fenton K, Mendoza N, Versteeg K, et al. Early Transcriptional Changes within Liver, Adrenal Gland, and Lymphoid Tissues Significantly Contribute to Ebola Virus Pathogenesis in Cynomolgus Macaques. J Virol. 2020;94: pubmed 出版商
Tian J, Ma K, Pei C, Zhang S, Li X, Zhou Y, et al. Relative safety of various spermatogenic stem cell purification methods for application in spermatogenic stem cell transplantation. Stem Cell Res Ther. 2019;10:382 pubmed 出版商
Havenar Daughton C, Carnathan D, Boopathy A, Upadhyay A, Murrell B, Reiss S, et al. Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization. Cell Rep. 2019;29:1756-1766.e8 pubmed 出版商
Caeser R, Di Re M, Krupka J, Gao J, Lara Chica M, Dias J, et al. Genetic modification of primary human B cells to model high-grade lymphoma. Nat Commun. 2019;10:4543 pubmed 出版商
Colonna L, Peterson C, Schell J, Carlson J, Tkachev V, Brown M, et al. Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation. Nat Commun. 2018;9:4438 pubmed 出版商
Somasundaram R, Zhang G, Fukunaga Kalabis M, Perego M, Krepler C, Xu X, et al. Tumor-associated B-cells induce tumor heterogeneity and therapy resistance. Nat Commun. 2017;8:607 pubmed 出版商
Quast I, Keller C, Maurer M, Giddens J, Tackenberg B, Wang L, et al. Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity. J Clin Invest. 2015;125:4160-70 pubmed 出版商
Bachanova V, Frankel A, Cao Q, Lewis D, Grzywacz B, Verneris M, et al. Phase I study of a bispecific ligand-directed toxin targeting CD22 and CD19 (DT2219) for refractory B-cell malignancies. Clin Cancer Res. 2015;21:1267-72 pubmed 出版商
Matsuda K, Dang Q, Brown C, Keele B, Wu F, Ourmanov I, et al. Characterization of simian immunodeficiency virus (SIV) that induces SIV encephalitis in rhesus macaques with high frequency: role of TRIM5 and major histocompatibility complex genotypes and early entry to the brain. J Virol. 2014;88:13201-11 pubmed 出版商
Jensen K, Brusletto B, Aass H, Olstad O, Kierulf P, Gautvik K. Transcriptional profiling of mRNAs and microRNAs in human bone marrow precursor B cells identifies subset- and age-specific variations. PLoS ONE. 2013;8:e70721 pubmed 出版商
Chicaybam L, Sodré A, Curzio B, Bonamino M. An efficient low cost method for gene transfer to T lymphocytes. PLoS ONE. 2013;8:e60298 pubmed 出版商
Dang Q, Whitted S, Goeken R, Brenchley J, Matsuda K, Brown C, et al. Development of neurological disease is associated with increased immune activation in simian immunodeficiency virus-infected macaques. J Virol. 2012;86:13795-9 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD20 Monoclonal Antibody (2H7), PE-Cyanine7, eBioscience
目录# :
25-0209-42
规格 :
100试验
价格 :
美国346
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µL (0.125 µg)/test
物种 :
人类
克隆 :
2H7
抗体亚型 :
IgG2b, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation. CD20 is expressed on mature and most malignant B cells, in a subpopulation of T lymphocytes and follicular dendritic cells. CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation. CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation. After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface. CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell malignancies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment. Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.125 µg)/test
别名 :
AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国