产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GluR2单克隆抗体(6C4)
目录 :
32-0300
规格 :
100微克
价格 :
美国375.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6C4
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 21
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 7
Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2,4,5,6
Hao J, Sun N, Lei L, Li X, Yao B, Sun K, et al. L-Stepholidine rescues memory deficit and synaptic plasticity in models of Alzheimer's disease via activating dopamine D1 receptor/PKA signaling pathway. Cell Death Dis. 2015;6:e1965 pubmed 出版商
  • 免疫组化; 小鼠; 1:75; 图 4
Vazquez Sanroman D, Carbó Gas M, Leto K, Cerezo Garcia M, Gil Miravet I, Sanchis Segura C, et al. Cocaine-induced plasticity in the cerebellum of sensitised mice. Psychopharmacology (Berl). 2015;232:4455-67 pubmed 出版商
  • 免疫细胞化学; 人类
Busskamp V, Lewis N, Guye P, Ng A, Shipman S, Byrne S, et al. Rapid neurogenesis through transcriptional activation in human stem cells. Mol Syst Biol. 2014;10:760 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200
Ho V, Dallalzadeh L, Karathanasis N, Keles M, Vangala S, Grogan T, et al. GluA2 mRNA distribution and regulation by miR-124 in hippocampal neurons. Mol Cell Neurosci. 2014;61:1-12 pubmed 出版商
  • 免疫印迹; 大鼠
Kennard J, Guevremont D, Mason Parker S, Abraham W, Williams J. Redistribution of ionotropic glutamate receptors detected by laser microdissection of the rat dentate gyrus 48 h following LTP induction in vivo. PLoS ONE. 2014;9:e92972 pubmed 出版商
  • 免疫印迹; 大鼠; 图 4
Eckert M, Guevremont D, Williams J, Abraham W. Rapid visual stimulation increases extrasynaptic glutamate receptor expression but not visual-evoked potentials in the adult rat primary visual cortex. Eur J Neurosci. 2013;37:400-6 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7
Gould T, O Donnell K, Dow E, Du J, Chen G, Manji H. Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test. Neuropharmacology. 2008;54:577-87 pubmed
  • 免疫沉淀; 大鼠; 图 6
Shukla K, Kim J, Blundell J, Powell C. Learning-induced glutamate receptor phosphorylation resembles that induced by long term potentiation. J Biol Chem. 2007;282:18100-7 pubmed
Morise J, Yamamoto S, Midorikawa R, Takamiya K, Nonaka M, Takematsu H, et al. Distinct Cell Surface Expression Patterns of N-Glycosylation Site Mutants of AMPA-Type Glutamate Receptor under the Homo-Oligomeric Expression Conditions. Int J Mol Sci. 2020;21: pubmed 出版商
Goldwaser E, Acharya N, Wu H, Godsey G, Sarkar A, DeMarshall C, et al. Evidence that Brain-Reactive Autoantibodies Contribute to Chronic Neuronal Internalization of Exogenous Amyloid-β1-42 and Key Cell Surface Proteins During Alzheimer's Disease Pathogenesis. J Alzheimers Dis. 2020;74:345-361 pubmed 出版商
Mockett B, Guevremont D, Elder M, Parfitt K, Peppercorn K, Morrissey J, et al. Glutamate Receptor Trafficking and Protein Synthesis Mediate the Facilitation of LTP by Secreted Amyloid Precursor Protein-Alpha. J Neurosci. 2019;39:3188-3203 pubmed 出版商
Wall M, Collins D, Chery S, Allen Z, Pastuzyn E, George A, et al. The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility. Neuron. 2018;98:1124-1132.e7 pubmed 出版商
Zhong C, Akmentin W, DU C, Role L, Talmage D. Axonal Type III Nrg1 Controls Glutamate Synapse Formation and GluA2 Trafficking in Hippocampal-Accumbens Connections. Eneuro. 2017;4: pubmed 出版商
Zhou Y, Kaiser T, Monteiro P, Zhang X, Van der Goes M, Wang D, et al. Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects. Neuron. 2016;89:147-62 pubmed 出版商
Kennard J, Guevremont D, Mason Parker S, Abraham W, Williams J. Increased expression, but not postsynaptic localisation, of ionotropic glutamate receptors during the late-phase of long-term potentiation in the dentate gyrus in vivo. Neuropharmacology. 2009;56:66-72 pubmed 出版商
Williams J, Guevremont D, Mason Parker S, Luxmanan C, Tate W, Abraham W. Differential trafficking of AMPA and NMDA receptors during long-term potentiation in awake adult animals. J Neurosci. 2007;27:14171-8 pubmed
Quinlan E, Lebel D, Brosh I, Barkai E. A molecular mechanism for stabilization of learning-induced synaptic modifications. Neuron. 2004;41:185-92 pubmed
Moga D, Janssen W, Vissavajjhala P, Czelusniak S, Moran T, Hof P, et al. Glutamate receptor subunit 3 (GluR3) immunoreactivity delineates a subpopulation of parvalbumin-containing interneurons in the rat hippocampus. J Comp Neurol. 2003;462:15-28 pubmed
Hof P, Lee P, Yeung G, Wang R, Podos S, Morrison J. Glutamate receptor subunit GluR2 and NMDAR1 immunoreactivity in the retina of macaque monkeys with experimental glaucoma does not identify vulnerable neurons. Exp Neurol. 1998;153:234-41 pubmed
Verdoorn T, Burnashev N, Monyer H, Seeburg P, Sakmann B. Structural determinants of ion flow through recombinant glutamate receptor channels. Science. 1991;252:1715-8 pubmed
产品信息
产品类型 :
抗体
产品名称 :
GluR2单克隆抗体(6C4)
目录# :
32-0300
规格 :
100微克
价格 :
美国375.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Human, Mouse, Non-human primate, Rat
应用 :
ELISA: 0.5-5 µg/mL, Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:100, Western Blot: 2 µg/mL
物种 :
Human, Mouse, Non-human primate, Rat
克隆 :
6C4
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD.
免疫原 :
Fusion protein containing amino acids 175-430 from the N-terminal region of GluR2.
格式 :
液体
应用w/稀释 :
ELISA: 0.5-5 µg/mL, Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:100, Western Blot: 2 µg/mL
别名 :
AMPA selective glutamate receptor; AMPA-selective glutamate receptor 2; GluA2; Glur2; GluR-2; GLURB; GluR-B; GluR-K2; glutamate ionotropic receptor AMPA type subunit 2; glutamate receptor; glutamate receptor 2; glutamate receptor B; glutamate receptor B flip isoform; glutamate receptor ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA2 (alpha 2); GRIA2; HBGR2; OTTHUMP00000165324; OTTHUMP00000220942; OTTHUMP00000220943
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国