产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
NMDAR1单克隆抗体(54.1)
目录 :
32-0500
规格 :
100微克
价格 :
美国375.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
54.1
反应物种 :
little skate, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 33
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| Li M, Yang S, Xing B, Ferguson B, Gulchina Y, Li Y, et al. LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment. Exp Neurol. 2015;273:190-201 pubmed 出版商
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| Thompson P, Egbufoama S, Vawter M. SNAP-25 reduction in the hippocampus of patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2003;27:411-7 pubmed
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Li M, Gulchina Y, Monaco S, Xing B, Ferguson B, Li Y, et al. Juvenile treatment with a novel mGluR2 agonist/mGluR3 antagonist compound, LY395756, reverses learning deficits and cognitive flexibility impairments in adults in a neurodevelopmental model of schizophrenia. Neurobiol Learn Mem. 2017;140:52-61 pubmed 出版商
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Williams J, Guevremont D, Mason Parker S, Luxmanan C, Tate W, Abraham W. Differential trafficking of AMPA and NMDA receptors during long-term potentiation in awake adult animals. J Neurosci. 2007;27:14171-8 pubmed
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Bigini P, Gardoni F, Barbera S, Cagnotto A, Fumagalli E, Longhi A, et al. Expression of AMPA and NMDA receptor subunits in the cervical spinal cord of wobbler mice. BMC Neurosci. 2006;7:71 pubmed
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Roussignol G, Ango F, Romorini S, Tu J, Sala C, Worley P, et al. Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons. J Neurosci. 2005;25:3560-70 pubmed
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Williams J, Guevremont D, Kennard J, Mason Parker S, Tate W, Abraham W. Long-term regulation of N-methyl-D-aspartate receptor subunits and associated synaptic proteins following hippocampal synaptic plasticity. Neuroscience. 2003;118:1003-13 pubmed
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Morrison B, Janssen W, Gordon J, Morrison J. Light and electron microscopic distribution of the AMPA receptor subunit, GluR2, in the spinal cord of control and G86R mutant superoxide dismutase transgenic mice. J Comp Neurol. 1998;395:523-34 pubmed
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Hof P, Vissavajjhala P, Rosenthal R, Fiskum G, Morrison J. Distribution of glutamate receptor subunit proteins GluR2(4), GluR5/6/7, and NMDAR1 in the canine and primate cerebral cortex: a comparative immunohistochemical analysis. Brain Res. 1996;723:77-89 pubmed
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Siegel S, Brose N, Janssen W, Gasic G, Jahn R, Heinemann S, et al. Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus. Proc Natl Acad Sci U S A. 1994;91:564-8 pubmed
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Jones K, Oblinger M. Androgenic regulation of tubulin gene expression in axotomized hamster facial motoneurons. J Neurosci. 1994;14:3620-7 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
NMDAR1单克隆抗体(54.1)
目录# :
32-0500
规格 :
100微克
价格 :
美国375.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Human, Mouse, Non-human primate, Rat
应用 :
ELISA: 0.1-1 µg/mL, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:10-1:50, Immunoprecipitation: 1-3 µg/mL, Western Blot: 1-5 µg/mL
物种 :
Human, Mouse, Non-human primate, Rat
克隆 :
54.1
抗体亚型 :
IgG2a
储存 :
-20°C
描述 :
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
免疫原 :
Fusion protein containing sequence from the intracellular loop between transmembrane regions III and IV of NMDAR1.
格式 :
液体
应用w/稀释 :
ELISA: 0.1-1 µg/mL, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:10-1:50, Immunoprecipitation: 1-3 µg/mL, Western Blot: 1-5 µg/mL
别名 :
GluN1; GluRdelta1; Glurz1; GluRzeta1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; glutamate ionotropic receptor NMDA type subunit 1; glutamate receptor; glutamate receptor ionotropic, NMDA 1; glutamate receptor subunit zeta 1; glutamate receptor, ionotropic, NMDA1 (zeta 1); glutamate receptor, ionotropic, N-methyl D-aspartate 1; GRIN1; M100174; MRD8; neurotransmitter receptor; NMDA R1 receptor C1 cassette; NMDA receptor 1; NMDA1; Nmdar; NMDAR1; NMD-R1; NMDZ1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMZ1; NR1; NR1C1; NR1C2; NR1C2'; NR1N1; pGluN1; Rgsc174; RP11-350O14.1
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公司信息
赛默飞世尔