产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
周期蛋白E单克隆抗体(HE12)
目录 :
32-1600
规格 :
200微克
价格 :
375美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
HE12
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:50; 图 2
Duchnowska R, Wysocki P, Korski K, Czartoryska ArÅ‚ukowicz B, NiwiÅ„ska A, Orlikowska M, et al. Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients. Oncotarget. 2016;7:550-64 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Gagou M, Ganesh A, Thompson R, Phear G, Sanders C, Meuth M. Suppression of apoptosis by PIF1 helicase in human tumor cells. Cancer Res. 2011;71:4998-5008 pubmed 出版商
  • 免疫印迹; 人类; 图 9
Korfali N, Srsen V, Waterfall M, Batrakou D, Pekovic V, Hutchison C, et al. A flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal. PLoS ONE. 2011;6:e18762 pubmed 出版商
  • 免疫印迹; 人类; 0.5 ug/ml; 图 s2
Lofmark S, de Klerk N, Aro H. Neisseria gonorrhoeae infection induces altered amphiregulin processing and release. PLoS ONE. 2011;6:e16369 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 6e
Rico Bautista E, Yang C, Lu L, Roth G, Wolf D. Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cells. BMC Biol. 2010;8:153 pubmed 出版商
  • 免疫印迹; 人类; 1 ug/ml; 图 2
Chimploy K, Díaz G, Li Q, Carter O, Dashwood W, Mathews C, et al. E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin. Int J Cancer. 2009;125:2086-94 pubmed 出版商
  • 免疫印迹; 人类
Al Ayyoubi S, Gali Muhtasib H. Differential apoptosis by gallotannin in human colon cancer cells with distinct p53 status. Mol Carcinog. 2007;46:176-86 pubmed
  • 免疫印迹; 人类; 2.6 ug/ml; 图 4
Jones A, Jonsson A, Aro H. Neisseria gonorrhoeae infection causes a G1 arrest in human epithelial cells. FASEB J. 2007;21:345-55 pubmed
  • 免疫印迹; 人类; 1:200
Lu L, Schulz H, Wolf D. The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells. BMC Cell Biol. 2002;3:22 pubmed
Gookin S, Min M, Phadke H, Chung M, Moser J, Miller I, et al. A map of protein dynamics during cell-cycle progression and cell-cycle exit. PLoS Biol. 2017;15:e2003268 pubmed 出版商
Giordano T, Kuick R, Else T, Gauger P, Vinco M, Bauersfeld J, et al. Molecular classification and prognostication of adrenocortical tumors by transcriptome profiling. Clin Cancer Res. 2009;15:668-76 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
周期蛋白E单克隆抗体(HE12)
目录# :
32-1600
规格 :
200微克
价格 :
375美元
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunocytochemistry: Assay Dependent, Immunohistochemistry: Assay Dependent, Immunoprecipitation: 1 µg, Western Blot: 1-2 µg/mL
物种 :
人类
克隆 :
HE12
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
Cyclin E belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available.
免疫原 :
全长, 重组, 人类周期蛋白E蛋白
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay Dependent, Immunohistochemistry: Assay Dependent, Immunoprecipitation: 1 µg, Western Blot: 1-2 µg/mL
别名 :
AW538188; CCNE; Ccne1; CycE1; CYCLE; cyclin E; cyclin E1; cyclin Es; cyclin Et; E-S; G1/S-specific cyclin-E1; pCCNE1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国