产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
桥粒芯蛋白2单克隆抗体(6D8)
目录 :
32-6100
规格 :
100微克
价格 :
美国399.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6D8
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫印迹基因敲除验证
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 免疫印迹基因敲除验证; 人类; 1:500; 图 1b
  • 免疫印迹; 人类; 1:500; 图 4a, 4d
Shelton W, Thomas S, Alexander H, Thomes C, Conway D, Dubash A. Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell-cell adhesion. Sci Rep. 2021;11:13295 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
LAW M, Ferreira R, Davis B, Higgins P, Kim J, Castellano R, et al. CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment. Breast Cancer Res. 2016;18:80 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 5b
  • 流式细胞仪; 人类; 图 2c
Ebert L, Tan L, Johan M, Min K, Cockshell M, Parham K, et al. A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis. Angiogenesis. 2016;19:463-86 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Peitsch W, Doerflinger Y, Fischer Colbrie R, Huck V, Bauer A, Utikal J, et al. Desmoglein 2 depletion leads to increased migration and upregulation of the chemoattractant secretoneurin in melanoma cells. PLoS ONE. 2014;9:e89491 pubmed 出版商
  • 免疫组化; 人类; 1:10
Wex T, Kuester D, Monkemuller K, Stahr A, Fry L, Kandulski A, et al. Assessment of desmosomal components (desmoglein 1-3, plakoglobin) in cardia mucosa in relation to gastroesophageal reflux disease and Helicobacter pylori infection. Hum Pathol. 2012;43:1745-54 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Chavez M, Buhr C, Petrie W, Wandinger Ness A, Kusewitt D, Hudson L. Differential downregulation of e-cadherin and desmoglein by epidermal growth factor. Dermatol Res Pract. 2012;2012:309587 pubmed 出版商
  • 免疫组化; 人类; 1:10; 图 1
Wex T, Monkemuller K, Stahr A, Kuester D, Fry L, Völkel S, et al. Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal components in oesophageal mucosa. Histopathology. 2012;60:405-15 pubmed 出版商
Hankir M, Seyfried F, Schellinger I, Schlegel N, Arora T. Leaky Gut as a Potential Culprit for the Paradoxical Dysglycemic Response to Gastric Bypass-Associated Ileal Microbiota. Metabolites. 2021;11: pubmed 出版商
Domke L, Franke W. The cell-cell junctions of mammalian testes: II. The lamellar smooth muscle monolayer cells of the peritubular wall are laterally connected by vertical adherens junctions-a novel architectonic cell-cell junction system. Cell Tissue Res. 2019;375:451-482 pubmed 出版商
Tan L, Mintoff C, Johan M, Ebert B, Fedele C, Zhang Y, et al. Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome. Oncotarget. 2016;7:46492-46508 pubmed 出版商
Silberberg M, Charron A, Bacallao R, Wandinger Ness A. Mispolarization of desmosomal proteins and altered intercellular adhesion in autosomal dominant polycystic kidney disease. Am J Physiol Renal Physiol. 2005;288:F1153-63 pubmed
产品信息
产品类型 :
抗体
产品名称 :
桥粒芯蛋白2单克隆抗体(6D8)
目录# :
32-6100
规格 :
100微克
价格 :
美国399.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunocytochemistry: Assay-dependent, Immunoprecipitation: 5-10 µg, Western Blot: 1-3 µg/mL
物种 :
人类
克隆 :
6D8
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
免疫原 :
人类桥粒芯蛋白2
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay-dependent, Immunoprecipitation: 5-10 µg, Western Blot: 1-3 µg/mL
别名 :
AA408168; ARVC10; ARVD10; Cadherin family member 5; CDHF5; CMD1BB; D18Ertd293e; desmoglein 2; desmoglein-2; DSG2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国