产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Synuclein alpha/beta Monoclonal Antibody (Syn 202)
目录 :
32-8200
规格 :
100微克
价格 :
美国449.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
同义词202
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
文章摘录数: 2
| 参考文献 |
|---|
Cabin D, Shimazu K, Murphy D, Cole N, Gottschalk W, McIlwain K, et al. Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein. J Neurosci. 2002;22:8797-807 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
Synuclein alpha/beta Monoclonal Antibody (Syn 202)
目录# :
32-8200
规格 :
100微克
价格 :
美国449.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 1-2 µg/mL, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1-3 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
同义词202
抗体亚型 :
IgG2a
储存 :
-20°C
描述 :
Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.
免疫原 :
Recombinant human alpha- and beta-synuclein.
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 1-2 µg/mL, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1-3 µg/mL
别名 :
AI838531; alphaSYN; alpha-synuclein; betaSYN; Beta-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Phosphoneuroprotein 14; PNP 14; SNCA; Sncb; Syn; synuclein alpha; synuclein alpha-140; synuclein beta; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor); synuclein, beta
更多信息或购买 :
公司信息
赛默飞世尔